St. john's wort Interactions
There are 633 drugs known to interact with st. john's wort, along with 1 alcohol/food interaction. Of the total drug interactions, 283 are major, 322 are moderate, and 28 are minor.
- View all 633 medications that may interact with st. john's wort
- View st. john's wort alcohol/food interactions (1)
Most frequently checked interactions
View interaction reports for st. john's wort and the medicines listed below.
- 5-HTP (5-hydroxytryptophan)
- Adderall (amphetamine / dextroamphetamine)
- Alcohol (contained in alcoholic beverages) (ethanol)
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- CoQ10 (ubiquinone)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Ginkgo Biloba (ginkgo)
- Glucosamine & Chondroitin with MSM (chondroitin / glucosamine / methylsulfonylmethane)
- Iron Sulfate (ferrous sulfate)
- Lexapro (escitalopram)
- Omega-3 (omega-3 polyunsaturated fatty acids)
- Probiotic Formula (bifidobacterium infantis / lactobacillus acidophilus)
- Prozac (fluoxetine)
- SAMe (s-adenosylmethionine)
- Super B Complex (multivitamin)
- Synthroid (levothyroxine)
- Tylenol (acetaminophen)
- Valerian Root (valerian)
- Vitamin B Complex 100 (multivitamin)
- Vitamin B12 (cyanocobalamin)
- Vitamin B6 (pyridoxine)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Xanax (alprazolam)
- Zinc (zinc sulfate)
- Zyrtec (cetirizine)
St. john's wort alcohol/food interactions
There is 1 alcohol/food interaction with st. john's wort.
Report options
QR code containing a link to this page
More about st. john's wort
- st. john's wort consumer information
- Compare alternatives
- Reviews (144)
- Side effects
- Drug class: herbal products
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.