Comparing 5-HTP vs Melatonin
5-HTP (5-hydroxytryptophan) | Melatonin |
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5-HTP (5-hydroxytryptophan) | Melatonin |
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Over-the-counter
Used for Anxiety, ADHD, Insomnia, Headache. 5-HTP may also be used for purposes not listed in this medication guide. |
Prescription and OTC
Supplemental melatonin is very effective at reducing symptoms of jet lag, particularly that brought about by eastward travel across five or more time zones. Melatonin may also be used to treat sleep... View more |
Related suggestions Insomnia
Popular comparisons
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More about 5-HTP (5-hydroxytryptophan) | More about Melatonin | |
Ratings & Reviews | ||
5-HTP has an average rating of 6.6 out of 10 from a total of 155 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 23% reported a negative effect. |
Melatonin has an average rating of 5.8 out of 10 from a total of 239 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 36% reported a negative effect. |
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Drug Class | ||
Side Effects | ||
Generic Availability | ||
N/A |
N/A |
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Pricing and Coupons * Prices are without insurance | ||
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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Dosage Forms Available | ||
N/A |
N/A |
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Brand Names | ||
N/A |
Bio-Melatonin, Melatonin Time Release, SGard, Sleep3 | |
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||
4 hours |
N/A |
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CSA Schedule ** View glossary of terms | ||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||
Category N
Not classified
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Category N
Not classified
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Drug Interactions | ||
A total of 98 drugs are known to interact with 5-HTP:
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A total of 319 drugs are known to interact with Melatonin:
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Alcohol/Food/Lifestyle Interactions | ||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||
No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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First Approval Date | ||
N/A |
N/A |
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WADA Class View World Anti-Doping Agency classifications. | ||
N/A |
N/A |
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More Information | ||
Patient resources | ||
Professional Resources | ||
Related Treatment Guide | ||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.