Zoledronic acid and Chills: What Users Say (Page 3)

• Jin...
• May 14, 2019

For Osteoporosis "I had zoledronic infusion March 19, and oh my days, I felt awful for three days... chills, shaking, sickness, lethargic, and then a month later started having problems with my tongue being dry, patchy, and sore, then problems started with my teeth. I wish to God I had never had zoledronic. One thing is for sure, I will not be attending the next appointment in March 2020."

• AJT...
• Taken for 6 months to 1 year
• March 23, 2023

Zoledronic acid for Osteoporosis "Has been a year since the first infusion. I had a high fever and chills the first night. The next morning, I passed out twice, flat on my back. Then a nosebleed started and lasted one day. Since the morning after, I have had 24/7 nose pain that is unbearable. My new doctor is trying to figure out what is causing it."

• Chi...
• Taken for 5 to 10 years
• December 22, 2019

For Osteoporosis "I had my first zoledronic infusion last March, and a few hours later, felt a bit chilled. Then, at 3 a.m., I woke with pain in every bone, with extreme pain in every past fracture site, almost unbearable in the newest fracture in my ribs. I also had nausea, loss of appetite, blurred vision, and temperature. Severe pain lasted almost 3 1/2 weeks. However, my quality of life has improved so much. For the previous 2 years, I was fracturing even cleaning my teeth-multiple rib, fingers, toes, sternum, and 7 back fractures-all taking up to 12 weeks to heal, then fracturing something within 2 weeks of getting moving again. Whilst I'm not looking forward to the side effects again next time, I will certainly take it again. I'm walking about again, haven't fractured anything since the infusion. Blurred vision still comes occasionally, but it's a small price to pay. Remind me I said this next March."

• Ani...
• Taken for less than 1 month
• November 25, 2019

For Prevention of Osteoporosis "Had my injection at the end of October 2019. That evening, I had severe chills, headache, bone pain, and vomiting with no appetite. Symptoms lasted about 4 days, with bone pain a little better. It’s been a month, I still have bone pain, very weak, and tired. Hate the way I feel, not sure if I’m going to do it again. I also had blurred vision, with my eyelids becoming so dry and itching severely."

• Lin...
• Taken for less than 1 month
• August 22, 2022

Zoledronic acid for Prevention of Osteoporosis "When suggesting Reclast, my APRN said I may feel flu-like for 3-4 days. She strongly encouraged adherence to keeping hydrated and using Tylenol. I had my infusion Friday afternoon with no issues. I continued hydrating and taking Tylenol every 6 hours as instructed. I was fine on Friday but began feeling fatigued Saturday morning. This got progressively worse during the day. I moved slowly and had difficulty staying awake. By night, I had body chills. I had some pain in the area of my bladder, and several of my teeth hurt. I took Tylenol before bed and woke on Sunday feeling better, no chills, no tooth pain. I still felt tired and had some bladder discomfort. I actually slept from 1 to 2:30 pm (I never sleep during the day). I woke up feeling better and even met a friend for dinner out. Today is Monday, and I am feeling pretty normal. Maybe the best thing to do is realize you are going to feel flu-like for a few days, plan to lay low, sleep as needed, hydrate, and take your Tylenol."

• jan...
• Taken for 1 to 6 months
• June 30, 2021

Zoledronic acid for Osteoporosis "I had my first infusion of Reclast in April. The only side effects I encountered were muscle soreness and chills for 2 days, for which I took Tylenol. After that, no problems. It will be about 1.5 years till I have a Dexa to prove whether it does any good. I do resistance exercise, walk, and take calcium and vitamin D, and hope to increase bone density. I am withholding a full rating of 10 until I get my Dexa results."

• MMM...
• Taken for less than 1 month
• February 23, 2023

Zoledronic acid for Osteoporosis "Monday morning was my first Reclast infusion. The infusion process was fine and easy. Took 1 Claritin and 325 mg Tylenol prior to the procedure. Monday night had deep leg pains and a burning sensation. Tuesday had chills, deep leg pain (like growing pains when I was a kid), and a headache. Wednesday had leg and lower back pain. Took Tylenol from Monday through Wednesday. Thursday is much better with lingering leg pain. The doctor’s office said that patients who have never taken osteoporosis meds before might have some pain and flu-like symptoms. In all, better than I expected (I was very anxious after some of the comments here), and hopefully the results will be good on my next bone density test."

• Pat...
• Taken for less than 1 month
• July 19, 2023

For Osteoporosis "I recently had an infusion of Reclast. After reading these reviews, I was never told to drink tons of water and take Tylenol prior. I was told to drink 2 bottles of water afterward. I didn't drink very much that morning. By midnight, I started getting so sick. Pain in my upper back, I could breathe deep, chills, body aches, cold then sweating, nauseous. I wasn't this sick when I had COVID. I barely could eat or drink. By the next night, I felt so weak, I could barely stand. So, maybe if I was advised about the preparation, I could have avoided 2 days of hell. Kind of makes me mad. All these drugs may help osteoporosis, but the side effects, especially long term, are bad. Difficult as we get older, if you don't treat it, it could be a bad thing in the long run, and treating it also has negative side effects."

• 54_...
• Taken for less than 1 month
• July 5, 2022

Zoledronic acid for Osteoporosis "After reading all of the really negative comments, I was very anxious. However, I'm a 54-year-old female diagnosed with the spine of an 80-year-old. I weighed the pros and cons of potentially having a really nasty flu-like several days vs. a potentially shortened and pain-filled, miserable life and decided that Reclast was worth it. I have arthritis in my knees, hips, spine, etc., so I was anticipating a nasty interaction, but that was not the case. I had my infusion at 9:30 on a Thursday morning and felt okay for most of the day. I woke up around 2:00 a.m. on Friday with aches, pains, and chills much like the flu, though the last time I got the flu, it was MUCH worse. I ran a low-grade fever for a few hours, but by Friday afternoon, I was able to go to the grocery store. I took off-brand arthritis-strength acetaminophen throughout and drank as much water as I could. I highly recommend Reclast if you're able to rationally weigh the pros and cons of being sick compared to BROKEN."

• Sed...
• Taken for 1 to 6 months
• July 17, 2021

Zoledronic acid for Osteolytic Bone Lesions of Multiple Myeloma "I was placed on Zometa by my oncologist as a preventive medication to avoid bone lesions and fractures. I was diagnosed with multiple myeloma earlier in the year. I fortunately do not have bone issues at this point, however, my doctor thought it might help with prevention. After my first infusion, I developed severe chills, fever, and terrible calf pain 24 hours later. The fever, chills, and pain fortunately disappeared about a day or two later, but the fatigue lasted for days. Before my second monthly infusion, I drank more water. This did seem to help with avoiding chills and fever, but 24 hours later, I again developed bad calf pain and realized I had edema in my legs. A day later, it is better, but again, I have horrible fatigue and bloating. The side effects of this medicine are worse than those of my cancer meds. I will have to talk to my doctor, as I am not willing to do this every month unless I really have to."

• Pag...
• Taken for 6 months to 1 year
• August 23, 2021

Zoledronic acid for Paget's Disease "I received the Reclast at 3 pm. At midnight, I woke up freezing. It felt like I was in a tub of ice. Took 2 hours to warm up. When I coughed, I had pain all over my chest and stomach. I had THC in my system. Smoking a joint made me extremely dizzy. I’ve smoked for 50 years and never felt dizzy. It is 8 months later and it’s still happening. This drug interacts with THC. Beware!"

• Anonymous
• Taken for less than 1 month
• May 9, 2022

Zoledronic acid for Osteoporosis "I’m an active, fit 69-year-old woman. I still work full time and am a daily gym visitor. Neither Prolia nor Evenity worked. My doctor recommended Reclast. I was simply advised to drink extra water. My infusion was in the morning. The day was uneventful until later in the evening, I had side effects of chills, feverishness, and body aches. A rough night followed by a rough morning. I actually fainted and, thank goodness, didn’t hurt anything. Days of fatigue followed. Lots of Aleve. Weird symptoms like severe pain in both thumbs! Writing now difficult. A bit better each day, but highly doubtful I’d do it again."

• Anonymous
• Taken for less than 1 month
• January 4, 2022

Zoledronic acid for Osteoporosis "I am a 63-year-old woman. I had my first Reclast infusion 5 days ago. I had a fever, chills, and a major headache that lasted all night after the procedure. I was not told to drink water or to take Tylenol prior. Make sure you do both! The next day I felt okay. The next night I had chills, fever, racing heart, and Tylenol helped. I have throbbing discomfort in my hips and a feeling of being 'unwell.' I hope this subsides."

• Anonymous
• Taken for less than 1 month
• February 11, 2022

Zoledronic acid for Osteoporosis "I am an active 56-year-old female with osteoporosis and degenerative bone disease. My dexy scan came back worse than the last one, so my doctor advised me about Reclast, said they thought it would help with my bone loss to help keep from losing any more bone. On Feb. 7, 2022, I went in for the first infusion. I drank 4 glasses of liquid before they did it, and I felt fine. They took blood work and hooked me up to the IV solution, ran it for a little bit, then started Reclast. After 45 minutes, they took the IV out. I went home and wasn't told what to do about any side effects, if any. I felt fine, went to bed at 11 p.m. that night, and by 1:00 a.m. I was shaking all over uncontrollably, freezing like I was taken out of a freezer, my bones were locked and felt like they were breaking. This has lasted 5 days. I can hardly walk, a lot of pain in my bones, swelling, and had a bursting headache I only had before from seizures, and I went to be tested for COVID, they said negative. So now I'm having an EEG to see if the medicine caused seizures. NEVER AGAIN."

• Sha...
• October 22, 2021

Zoledronic acid for Osteoporosis "I had my Reclast infusion on 10-19-21 and will say I was extremely nervous from all the negative reviews. However, my experience wasn’t bad at all. I’m on my 4th day after and feel great. I did, however, after 12 hours, develop fever, chills, body aches, headache, but they weren’t that bad. Very tolerable. The worst was the chills and severe night sweats on the second night. Felt a little tired and headache on the 3rd day, but great after. My Dexa scan was -2.4. I will get another bone density test and pray it’s improved. I will definitely do it again. Trust my doctors."

• Ali...
• Taken for less than 1 month
• August 4, 2022

Zoledronic acid for Osteoporosis "66 y/o female with recent diagnosis of osteoporosis. Have had osteopenia for years but unable to take Fosamax, etc., due to reflux. Took first Reclast July 18. Everything was fine for the first 24 hours, then had chills, fatigue, nausea, achy muscles, headache, and dizziness. All symptoms resolved in 3 days except dizziness, which continued for almost 2 weeks. The flu-like symptoms were bearable, but the prolonged dizziness scared me. I still get dizzy if I turn my head a certain way and have to sleep sitting up. I hope it helps my bones, but I don’t think I will take this drug again."

• Wil...
• Taken for less than 1 month
• March 8, 2022

Zoledronic acid for Osteoporosis "Had Reclast infusion last Thursday. I was fine during the day. I even rode my stationary bike the same night. But oh boy!! At 1:30 am, I woke up with chills and body aches like I had just done a marathon. I could not lift my left arm up, it was so painful. Every part of my body hurt, especially joints and areas that I have arthritis (osteoarthritis). I am at day 5, and the body, muscle, and joint pain are gone, but I have no energy, I am so tired, and I have this headache for 4 days that is bothersome. I called the infusion center, and the nurse stated headaches this far from the infusion date is not the norm to call my primary care doctor. Made an appointment. I would not tell anyone not to take this medication. Each person's reaction can be different. I believe that if this medication works as it is stated, I can deal with the temporary discomfort. But time will tell. All I know is I would rather have these symptoms that are not great than to have the pain of a fracture or, worse, be debilitated."

• Har...
• Taken for less than 1 month
• September 20, 2022

For Osteoporosis "Initially, chills and limb and joint pains, as well as general tiredness. A few days later, noticed I could not lift my left arm where the IV line had been, and stiffness and pain in my neck and upper back. The most awful was sudden swelling and stiffness of my knees. I never had anything like this before."

• Ver...
• Taken for less than 1 month
• January 15, 2022

For Osteoporosis "I can honestly say that this has been one of the worst experiences of my life. I’m 54 and live with regular pain due to rheumatoid arthritis, but the pain caused by this drug was another level. I hydrated before the infusion at 9 am and continued afterwards, went back to my desk to work, and all was fine until around 4:30 pm when I was finishing up a meeting and I realized my lower back was hurting. By 9 pm I had severe chills and every part of my body ached. That first night, the pain was almost unbearable and I could only get to the bathroom by having my wife help me. I must have vomited around 40 times. It really was the night from hell. Day 2 was pretty grim, but my wife got anti-sickness pills and codeine from our family doctor, which helped a little. This is day 3 and I can move about now slowly but still feel like I’ve been run over by a truck which then reversed over me. I have no idea how long it’s going to take to recover fully. I will NOT have this drug again."

• Anonymous
• Taken for less than 1 month
• June 26, 2022

For Prevention of Osteoporosis "On the afternoon of Friday the 24th, I received my first infusion. I have osteopenia, and I am a cancer survivor. I started taking acetaminophen, Gatorade, and water. When I woke up on Saturday, I had a lot of vertigo. The first 24 hours after the infusion, I only had a slight fever and warmth inside my body. After 24 hours, sporadic discomfort began in the bones, such as the knees and arms, moderate tiredness, and headache. On Sunday morning, the strong symptoms of chills began, pain in the bones of the legs, spine, ribs, and arms. I also had very real nightmares. The pains in the early hours of Sunday would go away and come back stronger. Then, I had a strong pain in the bones of my chest, as if they were opening my chest with their hands, for a few seconds, twice-a terrifying and very painful experience. The extreme tiredness continues, my eyes are a little red, very dry, and I have very deep circles under my eyes. Next year, I will not use this infusion again, it has been horrible pain. HORRIBLE."

• Anonymous
• Taken for less than 1 month
• March 4, 2022

Zoledronic acid for Osteoporosis "Within 24 hours, I had a killer headache, chills, muscle pain, bone pain, nausea, and dizziness. It's awful!"

• Pau...
• Taken for less than 1 month
• January 21, 2022

Zoledronic acid for Osteoporosis "After my infusion, I had a couple of days with feeling a little tired and chilled. By day 3, I was back to exercising and feeling good."