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Zoledronic acid for Osteoporosis User Reviews (Page 3)

Brand names: Reclast, Zometa, Aclasta

Reviews for Zoledronic acid

Commonly mentioned side effects
  • Anonymous
  • Taken for 1 to 6 months
  • June 19, 2023

"I took one infusion six months ago. After taking it, I woke up in the middle of the night with nausea, and my whole body was crippled up. I got to the bathroom and took ibuprofen. Was able to get back to the bed. Better the next day. A few days later, I had trouble walking, and my toes were numb. I still suffer from lower back pain and other side effects. Never again. I won’t know for a while if it was effective. This was much worse than the flu-like symptoms I read about."

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  • Ste...
  • Taken for less than 1 month
  • September 11, 2019

"Had my first Reclast infusion on 9/9/19. I was petrified after reading several reviews. The nurses reassured me they do this 5 days a week. The drug has been out for years. Glad to report no side effects yet. Think of it as a coating on your bones to keep you from breaking a bone. Will come back next year."

9 / 10
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  • Rec...
  • Taken for 2 to 5 years
  • September 5, 2015

"Had my second infusion three days ago and had absolutely no side effects both times. Experienced a dramatic 7-1/2% increase in bone density from the treatment after 8 straight DEXA scans reflecting consistent bone loss. Could not be more pleased."

10 / 10
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Frequently asked questions

  • Des...
  • Taken for 1 to 6 months
  • March 17, 2016

"After having osteopenia progress to osteoporosis and not tolerating oral medications, my doctor suggested Reclast. I had my first infusion on Dec 26, 2015 and within days suffered incapacitating pain in my hands. It was so bad, I couldn't hold a toothbrush without tears due to the pain. Additionally, I started to have severe upper jaw pain. The hand pain has improved but not gone away entirely. The jaw pain has not resolved at all, making it hard to chew. I would not recommend this drug to anyone and would NEVER, NEVER use it again."

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  • She...
  • April 12, 2015

"I have osteoporosis at age 49. I had Reclast on March 5, 2015. The side effects that I have experienced have been extreme. About 4 hours after the treatment, I felt a crushing sensation from shoulders to hips, difficulty breathing. Movement made it worse. Went to the ER, doctors administered IV Benadryl and steroid. I have experienced bone pain throughout my body, at times not able to move without pain. That has passed after 2 1/2 weeks. I have extreme tingling, itching, and redness in my entire body. The doctor put me on prednisone and hydroxyzine. This has not helped me. I am unable to sleep due to the itching. Has anyone else had these side effects? If so, what did you do to take care of it."

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  • Deb...
  • Taken for less than 1 month
  • August 23, 2019

"I had a Reclast infusion on 8/20/2019 for the first time. It took about 30 minutes to receive all of the medication. I was given water to drink while there. I left, did some errands, and felt fine. I had dinner with a friend and still felt great. I went to bed and woke up about 12 hours after receiving my dose with severe clavicle and neck pain. I took 500mg of Acetaminophen and started drinking water. I was concerned that I hadn’t consumed enough water prior to taking the treatment. I probably consumed close to 64 ounces of water during this time. The pain subsided enough for me to fall asleep around 8:00 am, and when I woke up later, my body felt achy, and I had a low-grade fever. Those symptoms were uncomfortable but tolerable compared to the severe pain earlier. I continued to take Acetaminophen to help with the aches and fever and woke up on day two feeling fine. In summation, my negative symptoms only lasted 24 hours."

7 / 10
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  • No...
  • Taken for 2 to 5 years
  • November 5, 2019

"I went from osteoporosis to osteopenia after the 2nd year infusion. No side effects, but they gave me Benadryl and Tylenol just before infusion. I am on year 4 and getting infusion tomorrow. I get one more year and then they say I will take a drug vacation."

10 / 10
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  • Bar...
  • September 29, 2019

"I just got this a month ago so I can't comment on the results. I do want to say I had NO side effects at all after getting the infusion. In fact, I went straight to work, did fine all day, and all the days afterwards."

10 / 10
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  • Mar...
  • May 25, 2019

"I chose Reclast over Prolia because of the cost savings. The infusion was given at 9 am and 7 pm. On that night, I was experiencing severe bone pain, fever, sweats, and blurred vision. The pain was so great that all I could do was moan and cry. This lasted for two days, and then the pain lessened. By early morning of day 3, I began to have chest pain. The pain came and went every few minutes for 15 hours. When I called to ask for pain medication, his response was, 'I’m not actively treating you for cancer, go to your primary care doctor.' My oncologist prescribed me this poison, and he didn’t want to help me. When the chest pain started, I begged to come into his office just to check me out. I felt like I was going to die, and their response was 'we can’t do anything for you, go to the ER.' Absolutely no empathy for his patient and clearly did not care for my well-being, physically or mentally. I will never take this drug again! Beware of taking Reclast."

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  • unh...
  • Taken for 2 to 5 years
  • April 26, 2018

"I had two infusions during a two-year period. One day, suddenly, I had so much pain in my upper leg. I had no trauma prior to the pain. A bone scan shows I had a typical fracture on my femur. The doctor didn't tell me about the side effects of the drug. I am so disappointed. I thought the drug was supposed to strengthen my bones but does the opposite."

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  • Slv...
  • December 13, 2015

"At age 54, failed my bone density had lost 20% of my bone mass in one year. I participated in two blind studies and increased calcium and intake. At the end of studies, I found I had the placebos but had some positive results but not enough. Had my first Reclast yearly infusion in 2012, no side effects, and regained 10% of lost bone at bone scan. Had the second yearly infusion this past October again no side effects, hoping for another positive scan in May."

9 / 10
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  • Pea...
  • Taken for less than 1 month
  • April 25, 2020

"I just got my infusion yesterday, and about 4 hours later, I got a terrible headache. I woke up this morning and felt so awful! The pain is terrible, all over my body, and I get terrible shooting pains in my shins, thumb, and hips. My back feels like it's been crushed! Hope this goes away soon! I don't know about getting this next year."

2 / 10
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  • Anonymous
  • Taken for less than 1 month
  • May 21, 2019

"Severe dizziness and muscle pain after 8 hours of having Reclast infusion. I could barely walk to my car after shopping at Costco. When I got home, I threw up, my hands shaking from holding my body up from throwing up. My ankles had severe shooting pains, ribs were also hurting. I would never have this done again!!! My identical twin sister opted not to have it done. Her bone density is slightly better than mine. She exercises and does resistance training three days a week. She lifts weights and feels great. I, on the other hand, sit and watch TV, read books, and play on my iPhone, but can’t do any of these things because of the severe pain. I think I am going to start and do strength training to increase bone density like my identical sister before I ever use this drug again! It is poison!!!"

4 / 10
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  • nom...
  • Taken for less than 1 month
  • June 19, 2023

"Ten days after getting this, I had flu-like side effects briefly, and my whole body was itchy with hives. Went to UCLA urgent care last night, I was put in a room with a burning and dying sensation, and I waited and waited. I finally ran out asking for Benadryl, and unfortunately was disapproved. I ended up walking out, thinking I could do better at home. The rash looks like Shingle hives, which I am vaccinated against. An antihistamine saved the unbearable itchiness on Sunday. Will never take this in my life and never go to urgent care."

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  • Anonymous
  • September 29, 2014

"I am 52 years old with no other medical problems. After having a Reclast treatment, I have had very few side effects. I took 1200 mg a day of Calcium Citrate and Vitamin D for about two weeks before my treatment and drank lots of water the day of the treatment, before and after. I was able to go back to work the day after my treatment with no pain."

9 / 10
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  • Gra...
  • December 11, 2016

"I had an anaphylactic reaction, and a week later still have muscle pains in every muscle, chest pain, 'blocked' ears, metallic taste in my mouth, grey tongue covering, constipation, and extremely painful feet, hands, and chest. This drug is POISON to my system. It will be in my body for over a year. Will these symptoms eventually ease?"

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  • Fir...
  • Taken for less than 1 month
  • May 6, 2020

"I am 60 years old, and I was also very worried about the Reclast infusion after seeing many reviews. I got my first Reclast infusion today at 2 pm. I drank lots of water the night before and throughout the day. I haven't experienced any side effects, but I will post an update in a few days!"

9 / 10
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  • Fat...
  • Taken for 1 to 2 years
  • December 12, 2015

"I was diagnosed with osteoporosis at age 47. After completing 2 years of Forteo treatment, I had an infusion of Reclast in Oct. 2014. I didn't experience any side effects from the drug. I walk five to seven times a week, take a monthly RX Vitamin D tablet, and ensure enough daily calcium with almond milk and supplements. My bone scan of 12/2015 shows a -1.3 T Score. I'm back in the osteopenic range - and very happy."

9 / 10
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  • Awa...
  • November 5, 2016

"Reclast is a bad drug. It made my wife terribly ill! All side effects were devastating! It should be removed from use! She is lifeless in bed. Had to take her to the ER for morphine and nausea meds and calcium. This drug is dangerous, and the FDA should be held responsible for its end results and its allowing of doctors to use it in the USA."

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  • Dia...
  • Taken for less than 1 month
  • March 24, 2020

"I had Aclasta 10 days ago and had quite a severe reaction where my body ached terribly all over, and I could barely walk for 24 hours. The next 2 days, I was left with my body feeling dull pain all over. Since the infusion, I’ve had the worst pain in my thoracic area, like I have a knife stabbing me, and it won’t budge. I had an X-ray, no broken rib. Had a massage, nothing will fix it. So hard sleeping. I had no idea I’d be left like this."

3 / 10
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  • mcv...
  • Taken for less than 1 month
  • December 17, 2023

"I am 72, and my last Dexascan showed that my bone density was now osteoporosis. My choices were Reclast or Prolia. I had taken Actonel and Fosamax for a number of years and was taken off of Fosamax due to acid reflux. I hadn’t had any osteoporosis medication for the past four years. After discussing this with my doctor, I decided to try the Reclast first. I was mostly concerned with side effects reported from each drug, so I was anxious about getting the treatment. I read the reviews and followed the advice from others about drinking plenty of water to stay hydrated and taking Tylenol. The nurse who administered my medication said that she had been giving this med for years now, and very few patients had reported any problems, and most of those were muscle pain that lasted a few days. I am happy to report that I have had no side effects from the Reclast. I will find out in a year if my bone density improves, but do not be afraid of this med if you need to take it."

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  • Luc...
  • November 22, 2016

"Hard to tell if this drug worked yet or not but it definitely made me sick. Got the infusion Friday and on Saturday I had a 102 Fever and could barely get out of bed. I had chills, I'm sweating all over the place, and my husband literally had to help me to the bathroom. I was dizzy and every bone in my body ached. By Sunday afternoon, I was a little bit better but four days later I'm still feeling achy and have diarrhea. I won't be doing another infusion."

2 / 10
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  • Eff...
  • Taken for 1 to 6 months
  • March 3, 2021

"Had an Aclasta infusion in June 2018, and I am still having adverse reactions. These are severe shivers, sweats, extreme tiredness, severe itching, loss of appetite, and nausea. Immediately after the infusion, I was unable to get out of bed for three days and had severe backaches. I have read that it can take up to 24 months to get it out of your system. I have gone past that time frame and am still suffering. I am so over it and will NEVER EVER have another infusion."

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  • Gra...
  • Taken for 1 to 2 years
  • August 27, 2020

"I’m 58 years old and had my first infusion in 2018 and then again in 2019. I just had another bone scan and found out my score is exactly the same. Luckily, not any worse, but it did not improve after 2 transfusions. I did have flu-like symptoms for 24 hours after the first infusion, but was fine after the second one. I take a daily calcium supplement plus D3. I was just curious if it’s normal for no improvement after two treatments. My score was -2.6."

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  • gra...
  • Taken for less than 1 month
  • September 30, 2018

"74 years old, has back pain, tests identified 2 compression spine fxs. Conservative treatment failed to give relief, had 2 ESIs (epidural steroid injections), then 2-level kyphoplasty (Vertebral Augmentation for Compression Fractures), next Reclast infusion, felt okay for about 5 hours but later back pain intensified, went to bed, started shaking like chills all over, finally fell asleep. The next morning was so weak, unable to get out of bed, husband rolled me on a rolling walker into the bathroom, assisted me on and off the commode, stayed the same the next day. On Monday felt a little stronger but severe neck and right thumb pain, mostly laying and sleeping in a recliner. Checked with the doctor and received no specific recommendations. The next day was able to go out to lunch but extremely weak, had another ESI 6 days after Reclast, got relief for that day and the next, but pain returned with a vengeance the following day and back in the recliner now 9 days post infusion. Never again."

2 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

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