Skip to main content

Viibryd for Major Depressive Disorder User Reviews (Page 2)

Viibryd has an average rating of 5.5 out of 10 from a total of 196 reviews for the treatment of Major Depressive Disorder. 45% of reviewers reported a positive experience, while 41% reported a negative experience.

Reviews for Viibryd

  • Rob...
  • Taken for less than 1 month
  • July 17, 2019

"Viibryd is my med, I have major depression and bi polar one and this med has changed my life - plus no sexual side effects, my anxiety is down and I can function and enjoy life again. I am on 20 mg I hope this works out for you and was helpful"

10 / 10
Was this helpful?YesNo
37 Report
  • Sarah
  • July 17, 2019

"Okay so I have MDD and have tried Paxil, Zoloft, and buspar. The Paxil made me aggressively angry all the time like ready to fight, zoloft made me more depressed, buspar was like a sugar pill and didn't do a thing. But this Viibryd has helped so much, I don't have manic episodes anymore, and I can enjoy music again, I'm painting again, I have energy and motivation, the only thing is it kind of has made me have a "wont take any crap from anyone" kind of mind set - I don't know if that's good or bad. I guess good in a way because I wont let people walk all over me anymore. I can finally stand up for myself."

9 / 10
Was this helpful?YesNo
36 Report
  • mrsward
  • November 12, 2019

"I have tried several of the mainstream medications for my MDD that did nothing but cause terrible bruising, hallucinations, insomnia, irritability, increased depression etc. I had given up on finding the right medicine for me. This was my last attempt at trying a medication before I decided to avoid them due to being let down so many times. I took a genetic test that showed I only had three medicines that were compatible with my body. I started on 20mg and only had minor GI tract upset. THAT IS IT! After four weeks, I could tell the medicine was working as I had become MUCH less tearful. After seven weeks, I am raising it to 40mg and know this medicine was the best option for me. I have been able to have an overall sense of happiness, I don't have nearly as many depressing days, and my interest in daily activities has returned. I am SO grateful for the genetic test and this medication. It has given me my life back."

10 / 10
Was this helpful?YesNo
34 Report

Frequently asked questions

  • Kip
  • Taken for less than 1 month
  • April 23, 2023

"Where do I begin? I have struggled with treatment resistant depression and complex ptsd for my whole life. I’ve been on every antidepressant under the sun. In the last decade my depression has been so bad that I’ve been on a combination of two antidepressants, switching one out for another every year or so as nothing worked. The last three years in particular have been awful. Constant anxiety, racing negative thoughts, deep despair and no enjoyment of life at all. I pleaded with my psychiatrist to try something new and he suggest Viibryd. I’ve been taking it for three weeks now and after a few days I felt utterly transformed. I feel positive in outlook. I feel energized, but not in an anxious way. My irritability is so much better. I get out of bed and feel happy to be alive. Socialising (which has been masking for me now for years) feels exciting and rewarding. My creative work is being better. The difference is night and day. So far this medication has changed my life."

10 / 10
Was this helpful?YesNo
11 Report
  • Anonymous
  • Taken for 1 to 6 months
  • January 3, 2015

"I've been taking Viibrid for 5 weeks, and my mood seems to be much more stable. It's nice to not have constant feelings of despair. The one problem it's giving me is extreme nausea and vomiting. Even so, the positive effects from Viibryd are great and I'm more than willing to keep taking it despite all the nausea."

8 / 10
Was this helpful?YesNo
56 Report

Are you taking this medicine?

  • This...
  • Taken for 1 to 6 months
  • September 21, 2016

"Was on Celexa but came off because of horrible side effects such as lack of focus, and EXTREME memory loss. I suffered in class because of this, I could not retain anything I learned and it didn't make me feel happy, just numb. I stopped it a few years ago. Started 10mg Viibryd a couple months ago and I feel happier, more focused and more ambitious than ever, I use it along side Vistaril for anxiety and Its incredible. For how bad of a rep it gets, its been a life changer for me. I am doing amazing in school now and I just generally feel right all the time now. Occasional brain zaps at night but they are infrequent. The payoff of this medicine is just too great to let a couple minor side effects stop me from taking it."

10 / 10
Was this helpful?YesNo
48 Report
  • eyecr...
  • Taken for 1 to 2 years
  • October 19, 2014

"Viibryd has been the best medication I have taken for my depression. I have tried a few others and had terrible results. Viibryd seems balanced. I feel more stable. Although i do have trouble with insurance covering the medication for some reason. I have great insurance."

10 / 10
Was this helpful?YesNo
56 Report
  • Water...
  • Taken for 1 to 2 years
  • March 29, 2017

"I've been battling MDD for 20 years. I'm 32. If you can name it, it's been prescribed to me. I went through a two month period of constant suicidal ideation in 2015 and was put on 40mg Viibryd. It saved my life, career, and sanity. I've been taking it as prescribed for 1 1/2 years and my depression doesn't control my life and thoughts anymore. I still get situational depression, but it doesn't spiral like it always used to. I experienced no side-effects. Highly recommended if you want to try something new."

10 / 10
Was this helpful?YesNo
43 Report
  • lulama
  • February 18, 2016

"I began taking Viibryd at the suggestion of my doc to use in addition to bupropion. After having been prescribed different antidepressants, the one drug that seemed to work to mostly maintain my mood was Wellbutrin. Though it worked well, from time to time crippling depressive episodes would bleed through. I have been taking 10 mg Viibryd with 150 mg bupropion per day and that works very well for me. I haven't had a single episode that I couldn't deal with even having gone through a death in my family and financial upheaval."

10 / 10
Was this helpful?YesNo
47 Report
  • Ellie...
  • February 9, 2016

"I have been taking Viibryd for three weeks now. I started on 10mg with food and instantly had severe diarrhea, dizziness, and just felt a little mentally absent. I went to bed that day, already feeling mental relief from lifelong MDD. My doctor had me reduce to 5mg for two weeks, which I did, and taking the pill with food and reducing the dosage helped tremendously. I am up to 10mg now and I feel absolutely amazing. The happiness that was mine as a child has returned. I am so glad to find this medication. I thought I was managing well enough with natural therapies and meds, but hit rock bottom this season with no unusually difficult things happening in my life. Science can be the miracle."

10 / 10
Was this helpful?YesNo
47 Report
  • KiloT...
  • Taken for 2 to 5 years
  • September 19, 2018

"Best medicine I’ve ever had. Got out of the Marine Corps in 1986. I’ve been on various anti-depressants and this is the best I’ve ever had. Perfect alignment with my misalignment in my cranium. On other meds I’ve had 3 episodes of suicide idealisation. I’m not even concerned about it anymore. I’m level-headed, not screaming at people, not being a total a-hole to my family. This medicine is a blessing to me."

10 / 10
Was this helpful?YesNo
35 Report
  • Mt...
  • August 30, 2016

"Im 37 y/o female and was prescribed this after a suicide attempt. Took just a few days but I feel the best that I have in a very long time. I can't tell you the last time I had the energy, enthusiasm, or Clarity that I have now. I've been on so many different antidepressants & anti-anxiety medications that I've lost track of what all I have been on. Best medication in combination with 5 milligrams of Abilify!!! I feel like I am getting my life back. I truly feel like my life has been saved. I did have loose bowels off and on the first two weeks, but now on week 3 it is getting better. My guess is, like any other antidepressant, some people respond in a positive way, and others respond in a negative way. Nature of the beast of depression!"

10 / 10
Was this helpful?YesNo
44 Report
  • Leni
  • November 16, 2015

"The only reason I gave it a 9 is because I can tell immediately if I miss a dose because it is as if my depression returns full fold as far as crying, irritability, anger and deep sadness. I use something else-Wellbutrin & Xanax bid for my anxiety. I have been on many anti-depressants and have dealt with PTSD and MDD since dx when 19. Probably had it prior but I was dx when I got to college because I was an A student who could not function. I tried this because my alternating Lexapro and Celexa (not at the same time) was no longer working and I am so happy that my NP found it. I had some tummy issues at first but they were gone after the first three weeks and I already have insomnia so that has not changed. I am the young Me again."

9 / 10
Was this helpful?YesNo
45 Report
  • CarrL...
  • Taken for 1 to 6 months
  • November 9, 2014

"I've been on Viibryd for less than 2 months. My depression is gone and I handle my anxiety better, but I feel disconnected and confused 80% of the time. I forgot how to write a cheque and get hot water several times. I also become very shaky and I feel like nothing is real and it takes everything in me to stay sane. It's working and making me worse all at the same time and I'm not sure if these side effects will go away or not, but I work a lot and I can't afford to not function. Viibryd is helpful and harmful to me right now and I'm not sure what to do. I'm going to stick with it for 12 weeks and if the negative side effects don't go away, I'm going to switch."

6 / 10
Was this helpful?YesNo
49 Report
  • bborc...
  • Taken for 1 to 2 years
  • February 20, 2024

"I have been on and off other antidepressants all my life. Some worked, some did not; some made me feel horrible (most of them did). I am really sensitive to side effects. This drug has been awesome for me. I noticed some changes very quickly. I had no side effects at all; I do take it with food. Overall, I really like this drug. It has really helped me to feel somewhat normal. I am a little worried as it doesn't seem to be working as well lately, but I am going to see about going up in dose. I am at 40 mg a day."

8 / 10
Was this helpful?YesNo
3 Report
  • Nymer...
  • November 15, 2014

"I've been on Viibryd (40mg) for a few months now, for major depression/anxiety. Before that, I took Prozac, but I felt like it had stopped working. The Viibryd is working well for me. I have more good days. I don't feel sedated, just more positive and functional. As far as side effects, I get an upset stomach if I don't eat before I take it. I took it right before bed one time and had a really vivid nightmare, so I try to take it early in the day. When I do miss a dose, I feel withdrawal more than I did with Prozac. Overall, it's effective for me, but I have to be more careful to avoid side effects."

7 / 10
Was this helpful?YesNo
48 Report
  • Syano
  • Taken for less than 1 month
  • February 23, 2020

"Within 3 days it gave me paralyzing existential thoughts and induced OCD. Dealt with this and other side effects like paranoia for about 2 weeks after stopping use. Please never take this drug if you don’t have a psychiatrist that can closely monitor you and help you if you have an experience like mine. 2 days on it I saw my therapist she told me to get off of it ASAP because every one of her patients that had taken felt suicidal. I have never had a medication mess me up this badly."

1 / 10
Was this helpful?YesNo
26 Report
  • Quail...
  • Taken for less than 1 month
  • January 29, 2017

"Horrible!l! I'm 36 and have NEVER been like this. I stared at a razor blade for 10-15 minutes before I realized what was going on. I called my doc as soon as they were open. I was a zombie. I was crying for zero reason, this drug did the exact opposite of what it's supposed to do."

1 / 10
Was this helpful?YesNo
39 Report
  • Depre...
  • Taken for 1 to 6 months
  • August 18, 2014

"Was diagnosed with clinical/major depressive disorder when I was a teen. I am now approaching 60 and have battled this all of my life. I had very good luck with Cymbalta starting in 2006 but within the past year the Cymbalta (120 mg/day) lost effectiveness and I had several serious depressive down cycles. My therapist put me on Viibryd (after trying some others) about 2 months ago. I have suffered the previously mentioned side effects: diarrhea, restless-legs, vivid dreams, some insomnia, but I feel much better mentally. My biggest problem has been in weaning myself off of the Cymbalta. Still on 20 mg day, and halving that on a weekly basis. Terrible withdrawal from Cymbalta!"

7 / 10
Was this helpful?YesNo
48 Report
  • MISS...
  • February 16, 2017

"This drug was miraculous!. It was as if I was waking from a 5 year nightmare. I was 'normal' again for the first time in YEARS!....HOWEVER!..Medicare won't let me have it and I certainly can't afford $300 a month on a fixed income. Why do they 'give' you samples, 'free' 30 supply but then rip it out from under you for $$$$$$. Now I'm on a generic Prozac and Lord only knows where THAT was made and "it ain't a workin'!"....I WANT MY VIIBRYD!"

10 / 10
Was this helpful?YesNo
38 Report
  • Drew
  • Taken for less than 1 month
  • August 8, 2019

"I had the gene psychtropic test done. I had been on 14 different antidepressants over the past 28 years and I either couldn't tolerate the side effects or they made my MDD worse. Starting real slowfor Viibryd at just 5mg with breakfast and after just 9 days it's starting to help my energy and I'm not so easily angered. A little GI upset and it makes me sleepy but then I have more energy overall. It was 1 of just 3 that gene test said may work. So far so good!"

9 / 10
Was this helpful?YesNo
28 Report
  • Kmaek
  • October 26, 2020

"This drug Viibryd is AWFUL. I have anxiety, panic disorder, PTSD, and major depression. If I don’t take this medication hours before I’m supposed to take it, I get “brain zaps” They are horrible and make my entire body move almost like a little seizure. I am about to get off this med because this past week had TRAUMATIZED ME. On 10/14/20, I ran out of medicine and the pharmacy was closed. I was experiencing extreme anxiety, paranoia, and when I tried to sleep, I was getting WAVES of EXTREME brain zaps. LISTEN, these brain zaps led me to paralysis. I don’t know if it’s sleep paralysis because I was awake but it happened 4 times in a 4 hour period. I could not move my legs, body, arms, head. But I could move my eyes. This was absolutely terrifying. Two nights ago, it happened again. But I didn’t miss a dose. I felt those same brain zaps and could not move. I hope no one EVER has to experience this."

1 / 10
Was this helpful?YesNo
22 Report
  • Jecc
  • Taken for 2 to 5 years
  • July 13, 2022

"Best thing that happened to me. I was plagued by depression for many years. Hopeless and suicidal. Repeated episodes of crying and unable to get out bed. I tried every antidepressant out there. I felt even worse on them. I had a DNA test for psych meds. I only could take two different brands. Tried the first one, Pristiq and it raised my heart rate. Switch to Viibryd. It was like a the dark cloud lifted after 2 weeks. I have been on this med for 3 years and haven’t had a depressive episode since. I’m on 40mg. The only issue I had the first week was stomach issues."

10 / 10
Was this helpful?YesNo
13 Report
  • RLC
  • October 2, 2019

"I have been on several anti-depressants lexipro, celexa, zoloft, wellbutrin and started taking Viibryd 3 years ago. It worked very well for me and I am taking 40 mg-the highest recommended dose-but now I have developed resistance to it so I am getting tired a lot, sleepy, etc. I will be weaning off with my drs help and starting a new one. I wanted to say, I am sorry to hear from some of you that you have had severe side effects. That was not the case for me. Some mild stomach upset initially...I remember feeling a good feeling, alert even, like someone was shining a flashlight on my brain. It felt good after feeling sooo down. I also take Lamotrigine for anxiety and the 2 worked very well together as well. I would recommend this drug for anyone who has suffered my major depressive disorder. It is worth trying because the results can be so positive! I was able to return to work full time and maintain my job well."

Was this helpful?YesNo
26 Report
  • PDano
  • Taken for less than 1 month
  • August 17, 2019

"I started taking Viibryd after I had the gene test. I was on Viibryd 10 mg for about 3.5 weeks, didn't make it to 20 mg. It helped with the depression but I never had such bad side effects on any other antidepressants. Daily diarrhea, bloating, gas, stomach pain and some shaking. Sexual side effects were negligible which was the only upside. But the insomnia was the worst. I was just never tired. I was taking melatonin and even Benadryl to sleep which gave me a couple hours a night. Don't stick with too long if you have bad side effects because I don't think they go away. No wonder I never heard of this drug before!"

1 / 10
Was this helpful?YesNo
26 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Major Depressive Disorder

Care guides