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User Reviews for Venlafaxine

Also known as: Effexor, Effexor XR

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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Venlafaxine Rating Summary

User Ratings
10
   
23%(29)
9
   
19%(24)
8
   
17%(22)
7
   
7%(8)
6
   
3%(3)
5
   
7%(9)
4
   
5%(6)
3
   
5%(6)
2
   
4%(4)
1
   
16%(20)
6.6/10 Average Rating
131 Ratings with 127 User Reviews

What next? Compare all 61 medications used in the treatment of Major Depressive Disorder.

Reviews for Venlafaxine to treat Major Depressive Disorder

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Effexor XR (venlafaxine): "It helped a little bit with my depression but the response was not enough. My doctor added other antidepressants and a mood stabilizer but the efficacy remained at the same level. My first days on it were not easy, and I noticed a significant weight again right on the next day. It was crazy to see how much weight gain you can have on antidepressants SO QUICKLY. After 6 months, my body fat went from 4% to 18%."

   
5.0

gcarvalhomaciel September 11, 2018

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"Been taking it for like a week now. Feel like I have a lot of energy and insomnia but I still feel like I have suicidal feelings. Idk I’m debating on sticking with it. I just need a break from these feelings."

805Pegasus (taken for less than 1 month) September 3, 2018

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Effexor XR (venlafaxine): "This has worked really well for me. I'd recommend it but I think with any of these type of drugs, everybody is different. There's some trial and error involved. Took about 2 years and a trip to a psyche ward before I found the right medication. I take this, busiprone, and remeron and it works for me. My only advice is if you take effexor, don't ever run out of it. I went 5 days without it and it's a pretty freaky withdrawal."

   
10

Some guy (taken for 1 to 6 months) August 29, 2018

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Effexor XR (venlafaxine): "STAY AWAY! RUN! For the years I was on this I was told by this new psychiatrist that I had schizophrenia, when my other psychiatrist had diagnosed me with major depression which is what I have. I was just going through a lot but effexor made me hear voices, and gave me the worst side effects. I couldn't even walk and I was so scared it was the most traumatic experience in my life. I am still trying to get back to normal I feel very disconnected."

   
1.0

Eyeball August 17, 2018

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Effexor (venlafaxine): "Horrible experience that I feel left me permanently damaged. Prescribed 37mg for panic disorder, social anxiety disorder, and major depressive disorder. Every symptom it was intended to treat got worse. I got so drowsy that I fell asleep through a 12 hour work shift as a caregiver, client had a fall and I did not wake up. I could not open my eyes no matter how badly I tried. Detoxing was worse. Unbearable body aches that made me more suicidal than I’d ever been because nothing relieved it. The brain zaps made me breakdown into a full panic attack crying every time because they were so painful and agitating. I’m 3 weeks off of it and having bizarre behaviors that I NEVER had before, even in my worst depression. I’ve had to give up my car keys from trying to drive off a cliff/into a wall suddenly with no warning and for no reason, I am unable to work because of my mental state that is NOT going back to baseline with time."

   
1.0

Jess (taken for 1 to 6 months) August 12, 2018

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Effexor XR (venlafaxine): "I switched to this from Prozac after trying many different SSRIs. Some didn't do anything, some helped quite a bit. Effexor XR being an SNRI made a world of difference compared to Prozac. At first I did get some mild headaches and was a little jittery, but once I got used to it after a few weeks the side-effects abated. Just stick with it and don't let the side-effects at first deter you."

   
9.0

Breezy (taken for less than 1 month) August 4, 2018

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Effexor (venlafaxine): "I was prescribed 37.5 mg of Effexor at the beginning then to 75 mg, then up to 150 mg. At that time I started having nausea. My dose was raised up to 225 mg, and there it got real bad. Strong nausea, vomit, brain zaps, anxiety so strong I could rip off my skin with my hands, stomach problems. I wasn't suicidal for a good time, until now. I thought my harsh past was the worst time of my life no. This so much worse. I was not able to see my psychiatrist so I had to deal with it alone, I lowered the dose, but I still had all these effects. Right now it's a day I'm off. I'm feeling brain zaps, fever feeling, can't do hard work, can't walk fast, difficulty eating and digesting, and anxiety. I've read some people responded well to this antidepressant, but if you are about to start taking this, don't. You either take it and it works OR it will bring you down, it's not worth it. Stay away from this, please."

   
1.0

anon23 (taken for 1 to 6 months) June 15, 2018

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Effexor XR (venlafaxine): "I'm on the Effexor 50mg dose. You can get a bead form or a tablet form. Well when I'm on the bead form it acts like I haven't taken it at all - I get dizzy, feel sick, often vomit but when I'm on the tablet form I'm fine."

   
1.0

becca (taken for 2 to 5 years) May 28, 2018

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"This was the first psych drug I ever tried, well before I developed a full blown disorder, and just the 37.5mg helped me get moving and focused on my work projects after suffering from a life loss that left me bed bound. It allowed me to return to everyday activities. I am now on 150 mg for MDD and have noticed an increase in positive mood...not in a bubbly, effervescent kind of way, just in a normal way. The only side effect I have from this particular medication (I take 2 others...Zyprexa and Anafranil) is tiredness. All in all, do not listen to all the horror stories about this medication and give just a small dose a try. You may like it. :)"

   
10

Nonaraza May 14, 2018

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Effexor (venlafaxine): "Within the first week of trying Effexor, I noticed it made me go to the bathroom excessively and I lost all of my sexual sensation. I did stay on it for another month+ to see if these symptoms would level out with time. They did not. So after 8 weeks, I am back to the drawing board to see if something else can work better."

   
3.0

Diane457 (taken for 1 to 6 months) April 24, 2018

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"Took one 37.5mg pill yesterday morning, and whammo!! Dizzy, nauseous, dry heaves, head felt like a football, disorientated, upset stomach, couldn't sleep......HORRIBLE drug for my system! Here it is the next morning & I'm still feeling wacked out! Will dump these pills back at the pharmacy..."

   
1.0

maniccanuck (taken for less than 1 month) April 7, 2018

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"I have been taking venlafaxine for 4 months, I am fatigued with a dry mouth, am very sleepy, especially in the morning."

   
1.0

Dee (taken for 1 to 6 months) April 4, 2018

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"Stay away from this drug. I have taken a lot of antidepressants but nothing came close to its side effects and withdrawal symptoms. First, it did not help with my depression. When I decided to stop it then it was hell on earth The doctor doesn't believe it is withdrawal. I went down from 300 mg to 37.5 mg in 2 months although the doctor said to do it in 3 weeks. The last 37.5 took me 2 weeks but since I stopped I have nausea and migraine everyday. The price is too high to pay for so little."

   
1.0

capaula (taken for 2 to 5 years) March 7, 2018

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Effexor (venlafaxine): "I was 17 years old when I was put on effexor (a few years ago) after many medications weren't working for my major depressive disorder. First month it didn't feel like it was doing anything but I didn't think much about it, I think a lot of people aren't aware of how common this drug makes people actually try commit suicide. I was told by one of my friends to not start taking this medication because it is known to make people go over the edge but I didn't listen and in the end this medication made all my symptoms worse after being on it for 4 months. I felt VERY suicidal and felt as though I was living in a dream or in a trance. I did end up trying to commit suicide while being on this medication I suggest everyone to NOT start this medication."

   
1.0

Lilbaby March 4, 2018

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Effexor XR (venlafaxine): "This is the best medication I have been given. It gave me my life back"

   
9.0

Sarah (taken for 10 years or more) March 3, 2018

5 users found this comment helpful.
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Effexor XR (venlafaxine): "I have been taking lamotragine but find it ineffective for depression. I was misdiagnosed as bipolar. I am considering taking venlaflazine again which worked to treat the depression for 12 years. I am a little wary though, realising now that all medications have bad side effects that at the time we tolerate. The down sides of venlaflaxine were irritability and unable to really relax. Tooth grinding, I lost and cracked 2 teeth and an inability to think or talk about my problems, armoured and ignoring them. Is it better to live calmly with some depression than none?"

PPOd (taken for 10 years or more) February 22, 2018

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"Effects: None Side effects: EXCESSIVE sweating, constant fatigue, low energy, HBP, 2 stone weight gain, increased anxiety, irritability and mood swings, memory loss/fog. Withdrawal effects: Brain Zaps (sometimes just in the head but strong ones radiate down my limbs and make me twitch) which mean I can no longer drive, effects vision too. Dizziness, memory loss/fog, hallucinations, painful skin, migraines with such sensitivity to light and sound I have to sit in the dark in virtual silence. Nausea, nightmares bad enough that I wet the bed, insomnia, flu like symptoms, itching all over skin, bad chest, terrible fatigue (fit 25 year old struggling to get to my upstairs toilet) and lastly RAGE. Extremely volatile rage. What they don't tell you about Venlafaxine in particular is that is works by acting on OPIOID RECEPTORS in the brain. So while it isn't an opioid as such, with no typical opioid effects, coming off this drug isn't anything like the others. Venlafaxine withdrawal is Heroin withdrawal. Look it up yourself if you don't believe me. Currently going through withdrawals of this medicine and honestly if I didn't have the amazing family I do, I'd be dead. I cannot believe I can't find any venlafaxine withdrawal related deaths or suicides. Drs shouldn't be allowed to prescribe this, its dangerous."

   
1.0

Terrible Drug. (taken for 2 to 5 years) December 19, 2017

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Effexor XR (venlafaxine): "I started Effexor after not being able to take Paxil due to headaches, and felt like trash after a week on Paxil, sexual side effects from Paxil as well. On Effexor 37.5 mg I feel better, less depressed, don't have alot of energy, but have less depressive thoughts after a week my dose was upped to 75 mg. After a week on 37.5 mg I noticed it was almost impossible to orgasm. On 75 mg it is impossible for me to orgasm. This is making me want to stop it, and try to find something else that may not effect me in this way. I don't have an issue with getting an erection and performing, it's just I can't orgasm. I have even tried generic viagra "sildenafil" which does improve the erection but still can't orgasm."

   
5.0

Deppressor (taken for less than 1 month) December 18, 2017

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Effexor (venlafaxine): "I have fibromyalgia and the doctors also diagnosed major depressive disorder. After a few attempts, I was prescribed Effexor, but I was never warned of the side effects or the horrible withdrawal symptoms if you ever want to stop. Research it first, I wish I had. I could not get my prescription for 4 days once and I felt like a drug addict, throwing up, sweating, headache, chest pains. It was severe. I think dying would have been a welcome option at one point. All because I had not realized I was out of refills. Anything that severe is not safe for your body. Now, I am stuck on a medication that has made me feel worse until I can do slowly wean off that it may take a year plus because it impacts your entire body when you cut back slightly."

Purduegoddess (taken for 2 to 5 years) November 20, 2017

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"The things you have to go through if you stop taking this drug are awful. I would never of started taking it if I knew how bad it is when you stop"

   
3.0

Anonymous November 15, 2017

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"I've been more than 5 years on this medications, there's a lot of true facts about this drug. It works, great in fibromialgya, I works better than a pure serotoninergic compound, or compares with escitalopram, that made my teeth a bit tight. Is true, if you want to get off this drug, you can have a hard time at the beginning so, better is to do it with a doctor, doing gradual reductions. For me is a good drug base treatment. With drive and motivation, try to use it in combination with Wellbutrin or rocket fuel as known in combination with Mirtrazapine 30mg has a very good synergic if you need a power effect. Or a guided treatment for ADHD."

   
8.0

Kusanovic (taken for 5 to 10 years) October 27, 2017

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Effexor XR (venlafaxine): "I've been on 75mg of venlafaxine for 6 or 7 years. It is good for me. Before Effexor, my emotions felt like being hit by a truck. After Effexor, it gives me a moment to THINK about things, rather than just disintegrating into a puddle on the floor. I still have feelings, but they're not as overwhelming and I don't feel like I HAVE to react to them. Side effects: sweating and tiredness. I take a lot of naps! Missing a dose: About an hour or two after my time to take my pill, if I forget to, I'd get tingly and dizzy. Withdrawal: I recently tried to stop taking Effexor cold turkey. I lasted 6 days. Intense anger, bursting into tears, a static feeling in my head, like a TV set on no channel, and a tingly feeling in my lips."

   
8.0

AfternoonMocha (taken for 5 to 10 years) October 22, 2017

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Effexor XR (venlafaxine): "I have been battling with major depression/anxiety since I was 12. I’ve been admitted in a mental institution twice. I’m now 18 yrs old, I’ve literally been on every med you can name. I was put on a type of B/P med to calm me down. It has, but I’ve still been so utterly depressed I can’t even function correctly. I saw my doctor yesterday and he put me on Effexor 37.5mg once a day. I took it around 4:00 pm (I couldn’t wait, things have to get better) and now here I am lying on the couch at 5:09am, I’ve been up since 11, with a little bit of nausea. Cannot go back to sleep..BUT I already feel better.. the heaviness and sad dwelling feeling is gone. It hasn’t even been 24 hours and I can breathe again.. Taking it in the morning instead."

Anonymous October 5, 2017

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Effexor XR (venlafaxine): "After an escalating two year psychotic depression I finally sought help- I was suicidal and believed I was beyond help. Olanzapine eased the psychosis but the deep dark depression I was in was relentless. It took a year of finding the right fit, prozac and citalopram didn't help me at all. Finally I was put on Effexor at 225mg and have been on it for 3 months. It has made a massive difference in a short amount of time. Don't take as long as I did to find the right combo, I assumed these drugs were more or less the same so thought they just couldn't help me. Effexor saved the day, and with olanzapine, my life!"

   
9.0

BPGirl40 (taken for 1 to 6 months) September 21, 2017

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Effexor XR (venlafaxine): "It was alright and helped a bit however being on one of the highest doses, missing a dosage was abysmal, one of the worst experiences ever. Try to find something else."

   
4.0

Anonymous (taken for 2 to 5 years) September 16, 2017

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