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User Reviews for Venlafaxine

Also known as: Effexor, Effexor XR

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Learn more about Venlafaxine.

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Venlafaxine Rating Summary

User Ratings
10
   
23%(26)
9
   
20%(22)
8
   
20%(22)
7
   
7%(7)
6
   
3%(3)
5
   
7%(8)
4
   
6%(6)
3
   
5%(5)
2
   
4%(4)
1
   
11%(12)
7.0/10 Average Rating
115 Ratings with 111 User Reviews

What next? Compare all 61 medications used in the treatment of Major Depressive Disorder.

Reviews for Venlafaxine to treat Major Depressive Disorder

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"Effects: None Side effects: EXCESSIVE sweating, constant fatigue, low energy, HBP, 2 stone weight gain, increased anxiety, irritability and mood swings, memory loss/fog. Withdrawal effects: Brain Zaps (sometimes just in the head but strong ones radiate down my limbs and make me twitch) which mean I can no longer drive, effects vision too. Dizziness, memory loss/fog, hallucinations, painful skin, migraines with such sensitivity to light and sound I have to sit in the dark in virtual silence. Nausea, nightmares bad enough that I wet the bed, insomnia, flu like symptoms, itching all over skin, bad chest, terrible fatigue (fit 25 year old struggling to get to my upstairs toilet) and lastly RAGE. Extremely volatile rage. What they don't tell you about Venlafaxine in particular is that is works by acting on OPIOID RECEPTORS in the brain. So while it isn't an opioid as such, with no typical opioid effects, coming off this drug isn't anything like the others. Venlafaxine withdrawal is Heroin withdrawal. Look it up yourself if you don't believe me. Currently going through withdrawals of this medicine and honestly if I didn't have the amazing family I do, I'd be dead. I cannot believe I can't find any venlafaxine withdrawal related deaths or suicides. Drs shouldn't be allowed to prescribe this, its dangerous."

   
1.0

Terrible Drug. (taken for 2 to 5 years) December 19, 2017

1 users found this comment helpful.
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Effexor XR (venlafaxine): "I started Effexor after not being able to take Paxil due to headaches, and felt like trash after a week on Paxil, sexual side effects from Paxil as well. On Effexor 37.5 mg I feel better, less depressed, don't have alot of energy, but have less depressive thoughts after a week my dose was upped to 75 mg. After a week on 37.5 mg I noticed it was almost impossible to orgasm. On 75 mg it is impossible for me to orgasm. This is making me want to stop it, and try to find something else that may not effect me in this way. I don't have an issue with getting an erection and performing, it's just I can't orgasm. I have even tried generic viagra "sildenafil" which does improve the erection but still can't orgasm."

   
5.0

Deppressor (taken for less than 1 month) December 18, 2017

5 users found this comment helpful.
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Effexor (venlafaxine): "I have fibromyalgia and the doctors also diagnosed major depressive disorder. After a few attempts, I was prescribed Effexor, but I was never warned of the side effects or the horrible withdrawal symptoms if you ever want to stop. Research it first, I wish I had. I could not get my prescription for 4 days once and I felt like a drug addict, throwing up, sweating, headache, chest pains. It was severe. I think dying would have been a welcome option at one point. All because I had not realized I was out of refills. Anything that severe is not safe for your body. Now, I am stuck on a medication that has made me feel worse until I can do slowly wean off that it may take a year plus because it impacts your entire body when you cut back slightly."

Purduegoddess (taken for 2 to 5 years) November 20, 2017

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"The things you have to go through if you stop taking this drug are awful. I would never of started taking it if I knew how bad it is when you stop"

   
3.0

Anonymous November 15, 2017

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"I've been more than 5 years on this medications, there's a lot of true facts about this drug. It works, great in fibromialgya, I works better than a pure serotoninergic compound, or compares with escitalopram, that made my teeth a bit tight. Is true, if you want to get off this drug, you can have a hard time at the beginning so, better is to do it with a doctor, doing gradual reductions. For me is a good drug base treatment. With drive and motivation, try to use it in combination with Wellbutrin or rocket fuel as known in combination with Mirtrazapine 30mg has a very good synergic if you need a power effect. Or a guided treatment for ADHD."

   
8.0

Kusanovic (taken for 5 to 10 years) October 27, 2017

1 users found this comment helpful.
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Effexor XR (venlafaxine): "I've been on 75mg of venlafaxine for 6 or 7 years. It is good for me. Before Effexor, my emotions felt like being hit by a truck. After Effexor, it gives me a moment to THINK about things, rather than just disintegrating into a puddle on the floor. I still have feelings, but they're not as overwhelming and I don't feel like I HAVE to react to them. Side effects: sweating and tiredness. I take a lot of naps! Missing a dose: About an hour or two after my time to take my pill, if I forget to, I'd get tingly and dizzy. Withdrawal: I recently tried to stop taking Effexor cold turkey. I lasted 6 days. Intense anger, bursting into tears, a static feeling in my head, like a TV set on no channel, and a tingly feeling in my lips."

   
8.0

AfternoonMocha (taken for 5 to 10 years) October 22, 2017

9 users found this comment helpful.
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Effexor XR (venlafaxine): "I have been battling with major depression/anxiety since I was 12. I’ve been admitted in a mental institution twice. I’m now 18 yrs old, I’ve literally been on every med you can name. I was put on a type of B/P med to calm me down. It has, but I’ve still been so utterly depressed I can’t even function correctly. I saw my doctor yesterday and he put me on Effexor 37.5mg once a day. I took it around 4:00 pm (I couldn’t wait, things have to get better) and now here I am lying on the couch at 5:09am, I’ve been up since 11, with a little bit of nausea. Cannot go back to sleep..BUT I already feel better.. the heaviness and sad dwelling feeling is gone. It hasn’t even been 24 hours and I can breathe again.. Taking it in the morning instead."

Anonymous October 5, 2017

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Effexor XR (venlafaxine): "After an escalating two year psychotic depression I finally sought help- I was suicidal and believed I was beyond help. Olanzapine eased the psychosis but the deep dark depression I was in was relentless. It took a year of finding the right fit, prozac and citalopram didn't help me at all. Finally I was put on Effexor at 225mg and have been on it for 3 months. It has made a massive difference in a short amount of time. Don't take as long as I did to find the right combo, I assumed these drugs were more or less the same so thought they just couldn't help me. Effexor saved the day, and with olanzapine, my life!"

   
9.0

BPGirl40 (taken for 1 to 6 months) September 21, 2017

5 users found this comment helpful.
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Effexor XR (venlafaxine): "It was alright and helped a bit however being on one of the highest doses, missing a dosage was abysmal, one of the worst experiences ever. Try to find something else."

   
4.0

Anonymous (taken for 2 to 5 years) September 16, 2017

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"Prevents dwelling on missed loved ones, crying, irritability, feeling left out, self-pity, resentment, bitterness. Has either hurt or failed to help low energy level, motivation, task initiation, and focus Worth it and would not want to try to live without it. If I miss a dose all that first paragraph stuff comes back but the worst is the physical brain zaps and dizziness upon standing & walking. If I miss it for 2 days or more, I get a fever and flu symptoms."

   
8.0

Anonymous (taken for 10 years or more) September 9, 2017

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Effexor XR (venlafaxine): "37.5mg makes life liveable again. The experience of missing a dose is not fun. Otherwise, this drug saved my marriage and my job."

   
9.0

RibbledyDabbleFrabbit (taken for 2 to 5 years) August 22, 2017

13 users found this comment helpful.
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Effexor (venlafaxine): "I have a significant loss of motivation but this is not new. Effexor has not helped this symptom."

Kjs1216 (taken for 6 months to 1 year) August 17, 2017

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"Effexor saved my life and marriage. I have major depression due to PTSD related issues. I had a really nasty childhood, then went into the Army and I am now a police officer. I also was an addict who was badly addicted to pain meds for about 12 years (on and off). No joke. I was really bad and I easily put away heaps and Tramadol with it. Yep, I was bad. I was "self medicating" to cover up the PTSD depression. Well, I did a lot of reading on psych meds and I saw that Effexor is structured similiar to Tramadol without the narcotic aspect. Well, I went to my doc, told her about it and I've been on it for about 9 months now and I feel wonderful. I also pair 225mg XR with 150mg of Wellbutrin."

   
9.0

Mike Bon Bon August 10, 2017

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"This is the only medication I have ever taken that I completely regret. I have been on at least six different medications for major depression. I gradually went up to a 225mg dose. I had horrible withdrawals from a missed dose, I would become dizzy and light headed half way through the day I missed a dose. I could barely leave my bed with how sick I would feel from withdrawals. I have moderate anxiety that became amplified on this drug. I became paranoid and had major anxiety attacks. I also started to have uncontrollable tics that interfered with my daily routine. And lastly, I gained more weight and I'm having difficulty loosing it. Now I am slowly being taken off the drug and I am miserable, I am so sick from the withdrawals."

   
2.0

Girltryingtofindtherightmeds (taken for 6 months to 1 year) August 2, 2017

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"The generic versions are inconsistent so I have stuck to the original Effexor 150mg and also the Sandoz equivalent. It's a very good treatment for depression and also alleviates the symptoms of ADHD to some degree. Assume it's the effect of the anti anxiety that helps me get my work done. I tried to "fool" the meds by consciously thinking about depression and the sad thoughts disappeared quickly so it has a very strong and positive effect on my life."

   
9.0

Delicious Monster July 10, 2017

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Effexor (venlafaxine): "Makes me very fatigued. Almost zombie like. I have a hard time concentrating on anything. Hoping it just takes some time to get in my system and work correctly. If not, going to see if I can get in something different."

   
6.0

Anonymous (taken for 1 to 6 months) July 6, 2017

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Effexor (venlafaxine): "Effexor I have tried many drugs but found that "in my case" they are not necessary. I went for an ultrasound on my carotid vein. The doctors said the flow was in the normal range but you could see that they were narrow. I went out of country to have them widened... No more anxiety and depression....drugs are cheaper and more profitable than minor surgery. I will return for stents. "

   
8.0

Bunsdad (taken for 1 to 2 years) June 21, 2017

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"Extremely effective and few side effects, which unfortunately include impotence."

   
9.0

AngryNeurotic (taken for 10 years or more) June 3, 2017

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Effexor (venlafaxine): "I've taken Duloxetine for years for major depression/osteoarthritis, but it never did much. My new psychologist wanted me to go off duloxetine and try a different A.D. **(Pro-tip - duloxetine can be titrated off of QUICKLY (within 2 weeks) if concurrent, temporary therapy of low-dose Prozac is performed at the same time. 10mg Prozac sufficient to prevent brain zaps and withdrawal syndrome from Duloxetine). I started with 75mg of Venlafaxine the first week. I didn't feel quite right, but not so bad that I felt I needed to report anything. After one week at 75mg per day, I began taking 150mg, a doubling. One day at 150mg was nearly the end of me. Immediately after it "hit" I became hostile, aggressive, suicidal, and unable to calm down."

   
1.0

Badkittym (taken for less than 1 month) May 12, 2017

9 users found this comment helpful.
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Effexor XR (venlafaxine): "I am currently on 150 mg of effexor XR. It isn't the greatest but I noticed that I don't have random crying spells anymore and my depression eased a bit."

   
8.0

DaynaS (taken for 1 to 2 years) April 30, 2017

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Effexor (venlafaxine): "Made me sick"

   
1.0

smiley2 (taken for less than 1 month) April 19, 2017

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"I suffer from severe leg pain and all over body pain that Dr says it is fibromylgia. Anyway I started taking 75.Mg. Venlafaxine from last few days and feeling kind of good. Pain is little so I feel good. But all the people's reviews are scary. I don't know what to do. but this medicine is good for anxiety and pain. it helps a lot."

   
9.0

Union square March 13, 2017

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"If I had to choose which medication to stop taking, either my heart medicine or my Venlafaxine/Effexor, I would rather go without my heart med! For years I went from doctor to doctor trying to get someone to do something about the depression that I had experienced since puberty. Everyone just blew me off. The doctor that finally put me on Effexor XR saved my life. This is not one of those meds that you have to wait forever to see results. I felt better right away! The crying spells stopped. I was talking to people again. I was getting my life back! It has caused weight gain, about 10 pounds per year. Just be aware of that. They have tried to take me off of it for that reason but nothing else helps nearly as much."

   
10

Sherry Lea March 13, 2017

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"I've been on this for over ten years. I don't recommend it to anyone who will ever want to get off it as withdrawal is HORRIFIC. No exaggeration. Has it helped the depression well enough so I'm functional? Absolutely. Has it "cured" me? No. It just makes life bearable. I should add that I also have BPD, so not being uselessly depressed all the time didn't solve everything. All that said, I have most recently stopped it (again ) thanks to my angry, destructive nature. I'd been on 300mg and did a quick lowering of dosage to get off it. I just want to be myself as a mess instead of a drugged-up version of myself as a mess. Isn't there something wrong when a drug so greatly changes your brain? Doesn't its bad withdrawal mean it's dangerous?"

   
9.0

Lopki (taken for 10 years or more) March 7, 2017

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Effexor XR (venlafaxine): "I am sure Effexor has helped many people over the years. I was one of the first patients to take Prozac I was given ever increasing doses as my depression increased. At first, I was HEALED! I wound up in hospital with psychotic break, due to SSRI's. Effexor was given to me a few years later ( Doctors still did not correlate medication as possible issue ) and again I got more depressed. At this point I was taking a bi-polar med Lithium. The Dr. abruptly stopped Effexor from a high dose., and I do not remember the next month. I was on the payphone in a psych- ward talking to my Mom and came back. The nurses said I do not want to know what happened. I take my meds everyday, at the same time, see my Dr. every 3 months, and am well."

   
1.0

Experimental One (taken for 6 months to 1 year) February 25, 2017

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