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Venlafaxine for Depression User Reviews (Page 5)

Brand names: Effexor, Effexor XR

Reviews for Venlafaxine

Commonly mentioned side effects
  • Fin...
  • September 16, 2019

Venlafaxine "Effexor almost ruined my life. When I was 13 and didn't fit in with my peers, my doctor decided that I must need antidepressants. This medication was useless in treating my depression as I was not actually clinically depressed. I was just a teenager going through teenage crap. I tried to go off the medications but would get sick with seizures when I tried. One day at age 26, I decided enough was enough and went off cold turkey. It was rough. I could not go to work, was getting seizures daily, and living with constant nausea. But after 3 months, I started to get better. The seizures became fewer and farther between, and the nausea stopped. Fast forward 10 years and I'm in a good career, am in great physical shape, have a stable mood, good self-esteem, an excellent credit score, and live the life I used to dream of living. Getting off Effexor was the best thing I have ever done for myself. It cleared my mind and allowed me to find myself."

1 / 10
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  • Jax...
  • Taken for 6 months to 1 year
  • September 13, 2022

Venlafaxine "I've tried several different meds for my lifelong depression. None worked. They made me sleep mostly. Effexor has been a miracle for me. Four days after I began taking it, I began to feel hopeful. After one week, I noticed I didn't want to give up anymore. I felt at peace. I'm so grateful for this medication. It's changed my life. Too bad I didn't have it 35 years ago when I was diagnosed. Thank you, Effexor."

10 / 10
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  • kam...
  • August 8, 2009

Venlafaxine "I gave this a high score because I got lucky. I went for years struggling with depression, weary of Big Pharma, self-medicating. Finally, a friend took me to a doctor. The first drug she prescribed was Effexor. I was prescribed the 75mg capsules. I found it to be too much for me, so I take one every other day. The only side effects I feel are from withdrawals if I skip a few days, and 'ditziness' if you will. Other than that, managing my depression has changed my life. My weight has even dropped because I used to self-medicate with food. I do recommend taking only the lowest dose possible for your symptoms. I am not a big fan of prescription drugs, but this was a lifesaver for me."

10 / 10
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Frequently asked questions

  • And...
  • March 13, 2012

Venlafaxine "I have been on Effexor for 15 years, 150mg per day, except for a 1-year period ending about 6 months ago. It is very effective for me. It made me tired when I first started it, but it was worth sticking through that. For my time not taking it, I was on Zoloft which didn't work as well. Effexor has kept me from depression, but it does other things for me. First, it reduces my inattentiveness to near nothing. Therefore, I am very productive at whatever I do. Second, it greatly reduces anxiety. Stress does not cripple me any longer while on this medication. Going off the medication has a weird withdrawal symptom that isn't painful, it's just odd. Do not go off the medication without a doctor assisting."

9 / 10
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  • Mar...
  • October 24, 2013

Venlafaxine "I entered the beginning stages of menopause, and my mood changed dramatically. I was getting very concerned as I had never felt so sad and hopeless. I could not stop crying, and things that normally I would not let bother me were becoming huge issues. I did not recognize myself. I am known as a glass-half-full kind of person, so the change was dramatic. I was put on 35mg of Effexor, and wow - what a difference. Surprise, surprise, my hot flashes stopped (I have since read it helps with that), my mood back to normal, and strangely my joints don't hurt so much, and I have more energy. The few negatives are I yawn a lot, and though I still enjoy sex, I cannot have an orgasm. I consider both minor due to feeling so much better."

10 / 10
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  • Ale...
  • Taken for 1 to 2 years
  • September 1, 2019

Venlafaxine "I’ve been on Effexor for about a year. I take 75 mg ER a day for depression associated with bipolar disorder and anxiety/panic attacks, which were at such a high level that it led to pseudo seizures. I have had amazing results. I had my first winter without a major depressive episode, and the episodes that I have now are nowhere near as intense. My anxiety is at all-time lows as well, and I am able to hold a job for the first time. This is all in conjunction with cognitive behavioral therapy and lifestyle changes. But the withdrawal symptoms from missing a dose are HORRIBLE! You get brain zaps, which are similar to vertigo, and flu-like symptoms such as aches/pains and upset stomach. This is in addition to your depression and anxiety levels skyrocketing. When I first started the med, I had some nausea and dry mouth for a couple of weeks, but it passed quickly. Overall, I have had amazing results."

10 / 10
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  • Lin...
  • Taken for 5 to 10 years
  • January 24, 2024

"It saved my life. Full stop. I've been on Venlafaxine (called Enlafax-XR in New Zealand) 150mg dose since 2017. It has cut my depressive episodes from basically every day to once a year. My anxiety has improved 80%, I still do experience it slightly, but not close to the extent I used to. Panic attacks went from once a month to NEVER. I hadn't had one since starting venlafaxine. Rather than feeling like a shell of a human, nauseous and sick from crippling anxiety and depression, I now feel normal and experience normal emotions. Nothing overwhelms me anymore. Give it a go. That first week of feeling weird is a drop in the ocean compared to the rest of your life. Don't give up because of a very temporary odd start. You'll forget about that as soon as you start feeling epic!!!"

10 / 10
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  • hol...
  • Taken for less than 1 month
  • May 29, 2019

Venlafaxine "After being admitted to the hospital following a panic attack and suicide attempt, I was prescribed Effexor because I had tried four different SSRIs and none worked, so the doctor thought I should try an SNRI. My first dose was 30 mg, and half an hour after taking it, I started to feel really weird-terrible headache, blurred vision, anxious/uneasy, jittery, and kept spacing out. The next day, they moved me up to 75 mg, and the headache went away, but the other symptoms remained. The next few days were awful. It gave me horrible social anxiety (which I don't normally have), and I couldn't get any work done because my eyes wouldn't focus and I would stare off into the distance for minutes at a time, sort of dissociating. Also made me SUPER lazy. It made me just want to sit on my couch and stare into space."

1 / 10
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  • kra...
  • August 19, 2013

Venlafaxine "I am a 23-year-old male suffering from extreme MDD and GAD. I have been taking 150 mg of Effexor XR and 15 mg of Remeron for two months. I have tried Celexa, Lexapro, Wellbutrin XL, Zoloft, Paxil, and Prozac, and this is by far the best medication! I have been lifted from the darkness and have had no side effects, including sexual dysfunction. Yay!"

10 / 10
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  • Eri...
  • Taken for 1 to 6 months
  • April 8, 2015

Venlafaxine "One of the best responses I have had to any antidepressant medication. At 150mg and I have suffered with depression for over 20 years. Within a week, I noticed a drastic improvement in my mood. Has far surpassed Prozac, Lexapro, and Cymbalta. Definitely recommend trying to someone suffering from depression, MDD, etc."

10 / 10
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  • pea...
  • May 23, 2016

Venlafaxine "I suffered depression and anxiety at a very difficult time in my life 5 years ago and have been on Effexor 75 mg since then. It took the edge off highly stressful situations and helped me to cope in a calm and positive way. :) Life has been good since then, even though family problems have endured (thankfully to a lesser extent). The side effect of nausea was to be expected during the first few weeks, but after that, no problems at all. Effexor has been a wonder for me. :) :) :)"

10 / 10
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  • Not...
  • September 28, 2015

Venlafaxine "After a suicide attempt that landed me in the hospital's psych ward for three weeks, I was put on Effexor XR and Lamotrigine as a mood stabilizer. This combo has changed my life. It took a few months to get the dosage right (yes, MONTHS), but I'm coming up on two years since I've been hospitalized with little to no problems. I'm 21 and finishing my post-secondary education, hold a part-time job, live on my own, and have loving and supportive relationships. I never thought it would get better until Effexor came around."

9 / 10
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  • Anonymous
  • September 22, 2008

Venlafaxine "I was on Effexor XR for 8 years and I recently went off. I gave the drug 8 out of 10 because overall my anxiety and depression were greatly improved. I didn't have any sexual side effects and only felt dizzy when I did not take the medication at exactly the same time every night. I did lose a lot of my energy and was prescribed Wellbutrin to help out with that. However, the withdrawal, as others have mentioned, is terrible. My doctor prescribed a low dose of Prozac (20mg) to ease the withdrawal, and it really helped. If you are going off Effexor, do it with Prozac. I tried without it twice before, and it was such a horrible experience that I went right back on."

8 / 10
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  • Isa...
  • Taken for 10 years or more
  • July 21, 2018

Venlafaxine "I had suffered for years with anxiety/depression back in the '80s and '90s. Back then, there was very little medication to help. In the late '90s, my doctor put me on Prozac, which helped profoundly until it stopped working after 10 years. Then Effexor XR was introduced, this medication was a godsend, and I still take it daily for the last 18 years. Now, I'm able to concentrate when I read and enjoy a happy and fulfilled life!"

10 / 10
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  • Bra...
  • Taken for 1 to 6 months
  • December 5, 2014

Venlafaxine "This medicine literally saved my life. I took 75mg and the first day I took it, I noticed a difference in my mood. I woke up in the morning and actually felt like getting out of bed. I smiled and enjoyed being around people and was in a pleasant mood. I was getting my life back! The only side effect I noticed was that I was pretty nauseous the first week and lost my appetite. But, it wasn't bad at all! I stopped taking the medicine suddenly when I found out I was pregnant and the only side effect I noticed when I stopped was being dizzy for about a week. But that could've been because I was pregnant too. Unfortunately, I had a miscarriage, and started taking Effexor again. Looking forward to being happy again."

10 / 10
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  • Gin...
  • October 20, 2013

Venlafaxine "I have been on Venlafaxine XR for 8 years (first Effexor XR then generic without problems). Started at 150, then plateaued after about a year, went up to 225 and plateaued again. I have been on 300mg dose for over 5 years. I like this prescription a lot. I haven't tried other antidepressants, I was started on this because it worked for other family members. I know it's a high dose and some people are shocked, but I find this offensive and more or less stigma about mental illness and meds. I started Adderall about 4 years ago and that combination has been incredible for my depression (and ADHD). My sex drive recovered 3 months into VFX. The only complaint is when I miss a dose, in which case I have a lot of complaints: migraines, dizzy, tremor, hypersomnia"

9 / 10
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  • sel...
  • Taken for 1 to 6 months
  • July 25, 2025

"Fastest acting antidepressant I've ever been on. It alleviated my depression within one week and, after an increase to 150 mg, totally obliterated my tiredness/lethargy. Fantastic. On the other hand, it destroyed my sleep - I typically got 3-4 hours of fragmented sleep, and only after taking a sleeping pill. I had to go off the medication because of that after two months. Don't be afraid of the withdrawals, do a cross-taper with an SSRI (I used Lexapro). Apart from some tiredness for about a week I didn't have any problems."

8 / 10
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  • her...
  • September 8, 2007

Venlafaxine "My girlfriend has been on Effexor XR for almost seven years now. We just found out two weeks ago she is pregnant. The doctor told her to lower doses from the 300mg she has been on to 150mg, then three days later drop to 75mg, then three days to 37.5mg, then you're done. The doctor said that there might not even be any withdrawals if it is done this way. I wouldn't wish these bad withdrawals on anyone."

4 / 10
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  • Reg...
  • Taken for 6 months to 1 year
  • June 2, 2015

Venlafaxine "Effexor has been the most effective antidepressant for me. I've tried 5 SSRIs. Effexor doesn't make me lazy or spaced out. I feel it helps my cognitive functioning, as well as focus, motivation, and memory. I will go off Effexor for periods of time, plenty of time for my brain/body to reset, but I keep finding it better to be on Effexor. It's helped me to not be so negative, irritable, and just miserable overall. I can feel its slight pain-killing effects as well. It keeps me doing things instead of laying in bed ruminating negative thoughts. Side effects for me are constipation and lower libido. Miralax fixes the first one. As for the second one, before Effexor, I wasn't socializing at all anyways, so I can handle that side effect."

9 / 10
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  • Wan...
  • Taken for 2 to 5 years
  • November 2, 2019

Venlafaxine "Effexor ruined my life. After 3 years, I am in complete agony. Pain all over, and it stopped working. I tried to switch to another drug, and the withdrawals are much worse than heroin. My body is crunching all over. Haven't slept in months. Can't use my brain. Stay away from this!!! I can't work, I am on my own and will be homeless soon! The withdrawals are unbearable! Doctors' tapering is wrong!"

1 / 10
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  • Aus...
  • Taken for 6 months to 1 year
  • January 10, 2016

Venlafaxine "Awesome! Changed my life for the better completely. Side effects are minimal, but my mood has stabilized like never before. I wish I was medically compliant earlier. This stuff has changed my life for the better!"

9 / 10
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  • The...
  • October 23, 2014

Venlafaxine "I started this medicine in nursing school. Very much so needed. I started seeing myself with less worry, and a more 'whatever' type of mentality. I figured that worked for me. However, my biggest problem has been the weight gain. Before I knew it, I gained at least 25 lbs. I'm a very active person and I watch what I eat, especially since I am a cardiac nurse. Also, make sure you NEVER miss a day of the medication. My side effects would be vertigo and shooting nerve pains in my head. I just upped my dosage to 150mg hoping it will increase my energy and help with weight loss. I was really bad off emotionally before, so besides everything above, I have my life back."

6 / 10
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  • jan...
  • Taken for 10 years or more
  • August 26, 2013

Venlafaxine "Been on this for over 10 years. I take 2 different doses every morning - 75 mg and 37.5 mg (which was added about 3 years ago). While no drug is perfect, it has saved my life - both figuratively and literally. I've had great success with this medicine. Be forewarned though about missing a day: loopy feeling, lightheaded or a weird feeling in your head (not pain), like a short buzzer effect. Over the years, if I missed a day, I actually did not feel comfortable driving. If you miss 2 days you'll experience heart palpitations and will definitely feel bad. These are the reasons why this medicine should never be suddenly stopped. The dose should gradually be lowered. Conversely, the medicine should be started on a low dose, working up as needed."

10 / 10
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  • Tay...
  • Taken for 1 to 6 months
  • November 3, 2016

Venlafaxine "I've been taking Effexor for 5 months now, and I can say it definitely has worked for me. It can take time to actually start working, though, so give it some time. The only downfall is if I forget to take it for a day, I start getting dizzy, brain zaps, and headaches. I am now waiting to refill it, and haven't taken it for about a week, and the symptoms are still occurring. Even with that said, I would recommend this medicine for depression/anxiety. I no longer cry all the time for no reason. Definitely has changed my life (:"

9 / 10
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  • Sof...
  • Taken for 1 to 6 months
  • April 30, 2015

Venlafaxine "I take the drug in the morning when I wake up. The first thing is eating, then 75 mg with a bottle of water, and I make sure during the day to drink plenty of water because this drug affects your renal and hepatic system. Every three months, or according to your MD, you should do routine labs. Remember, the drug won't take effect fast; it is going to be two weeks to check out how you are tolerating the dose. During these first two weeks, you may feel somnolence, dizziness, tiredness, and an urge to sleep. That's normal, but you can also feel like you can't control your life, not being focused, and unhappy. That can also occur in the starting period, as it did for me. The maximum effect of the drug/dose will take effect in three months. Monitor your suicidal thoughts with any anti-depression medication."

10 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.