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Vedolizumab and Nausea: What Users Say

Brand names: Entyvio, Entyvio Pen

Nausea: mentioned by 9 users (4.9%)

Based on user experiences from 185 Vedolizumab reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

fatigue 15.7%
joint pain 13.0%
hair loss 9.2%
headaches 8.6%
tiredness 8.6%
pain 5.9%
diarrhea 4.9%
nausea 4.9%
chills 3.2%
dizziness 3.2%

Reviews for Vedolizumab

Commonly mentioned side effects
  • Pea...
  • March 12, 2021

Vedolizumab for Ulcerative Colitis "I’ve had UC for 37 years. I’ve been on Entyvio for 12 months. I chose to stop due to the debilitating side effects. I am in remission now, however, the side effects are not worth it. After my first infusion, I felt I was having a heart attack. The EMTs said my heart was fine, but I was close to having a stroke. Cortisone injections eliminated this symptom. Over 8 treatments, I developed severe bone and joint pain, some hair loss, major skin dryness and bruising, extreme fatigue, extreme chills and sweats, mouth sores constantly, 24/7 nausea and loss of appetite, some tremors, depression, boils appeared including around my eyes. I developed a serious eye infection after the 8th injection. The ophthalmologist said he’s only seen this type of eye infection in chemo patients. My olfactory senses became affected. Food started tasting different and fragrances seemed off. Entyvio did work, but it’s clearly a toxic drug to where the quality of life is impacted severely in my case."

2 / 10
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  • AKa...
  • Taken for 1 to 6 months
  • June 13, 2019

Vedolizumab for Crohn's Disease "I have struggled with Crohn's disease for many years. I have been able to lead a normal life with Remicade IV every 8 weeks, it was the best med for me until now. Unfortunately, it stopped working. My GI doctor put me on Entyvio. I'm on my second dose and not happy. I'm very concerned. I'm having symptoms that set me back 15 years. I have nausea, vomiting, diarrhea, joint pain, skin lesions, headaches, blurred vision, and fatigue. I had to take off several weeks of work also. I would not recommend this medication. I'm working with my doctor now for a new plan."

1 / 10
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34 Report
  • Cha...
  • December 26, 2017

Vedolizumab for Ulcerative Colitis "DO NOT TAKE ENTYVIO!!! That is, of course, unless you want your immune system to shut down and be unable to fight off even the littlest common cold. Not to mention the crazy amount of debilitating side effects: headaches, sore muscles, major fatigue, restless leg syndrome, feeling like you want to throw up out of the blue, back pain, and coughing. Oh, and if you do happen to get a cold while you're already experiencing these side effects, you might as well multiply the pain by 3 and prepare for a very long recovery as your body is too weak to fight off any disease. As for my colitis symptoms... Entyvio almost TRIPLED my symptoms!! Constant diarrhea, non-stop abdominal discomfort, and literally you are up all night. AVOID BY ALL MEANS!"

2 / 10
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48 Report

Frequently asked questions

  • Anonymous
  • Taken for less than 1 month
  • August 17, 2017

Vedolizumab for Crohn's Disease "Only on my second injection, migraine so bad I get nauseous, ears ringing, hear my heartbeat in ears all the time. It's elevated constantly, light hurts my eyes, dizzy, head goes black for seconds. Only going bathroom every three days. Scared to take my next dose."

2 / 10
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19 Report
  • Lin...
  • February 8, 2018

Vedolizumab for Crohn's Disease "Just had second treatment. My treatments have been every 2 weeks. Crohn's is still the same, no pain relief at all. One hour after infusion, nausea starts, diarrhea, joint and muscle pain, stomach pain, hot flashes, tired but trouble sleeping. Not sure if this is right for me."

2 / 10
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13 Report

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  • Anonymous
  • Taken for 1 to 6 months
  • May 2, 2022

For Crohn's Disease, Maintenance "Started vedolizumab in December 2021, had two infusions and then started using the Entyvio pen every two weeks. Started to get huge injection site reactions where my leg swelled up and was super itchy, hard as a rock, and hot, so was switched back to the infusions. Since this last infusion about 10 days ago, I feel so tired and sleepy, have nausea every day, and feel dizzy. My eyes are sensitive to the daylight, don't have headaches or that, but feel like a weird sensation throughout my body, plus have a lot of joint pain. I feel like I'm going crazy, and people think I'm a hypochondriac :( Gonna see if I can change to something else because this feeling is awful. Was getting flares every couple of months, but I dunno which is worse. Anyone else feeling this?"

5 / 10
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  • Nev...
  • Taken for 1 to 6 months
  • September 30, 2021

For Crohn's Disease "I had my 2nd loading dose. It floored me, constant nausea, a weird popping sensation in my brain. Severe muscle aches and spasms. A year later, I am still the same, no better. That stuff has ruined my life. I'm now waiting in a pandemic (have no clue when I will get seen) to see a neurologist. I saw a rheumatologist and have been diagnosed with fibromyalgia, which the consultant has said is due to vedolizumab. Many people have success. This has ruined my life."

1 / 10
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More FAQ

  • Wor...
  • Taken for 1 to 6 months
  • March 24, 2017

Vedolizumab for Crohn's Disease "Flushing similar to hot flashes, nausea, severe headaches/migraines, increased diarrhea the day of infusion for up to two weeks after."

1 / 10
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  • The...
  • Taken for 1 to 2 years
  • March 8, 2017

Vedolizumab for Crohn's Disease "Stayed on it for over a year. Took in combination with Entocort. Saw little to no improvement. Gave significant side effects such as flushing, fevers, nausea, chills, severe migraines, etc."

3 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.