Vedolizumab and Rash: What Users Say

• Gum...
• December 19, 2019

For Ulcerative Colitis "I have been taking Entyvio for a year now, and I am doing great. I had UC (ulcerative colitis) for 22 years now. I have tried every medicine out there, nothing worked for long, but with this medicine, I’m fine. The only side effect I experience is fatigue and a rash once in a while, but I love this medicine. I feel human again."

• Ale...
• March 15, 2017

For Ulcerative Colitis "I just wanted to write to thank everyone for their feedback and advice. My gut feeling was to not go in this even though drs told me Entyvio is the best, safest thing (apparently not). I have a friend who's decided to go on it about 3 infusions now and not well. Severe joint pain and sore bones throughout, as well as dealing with a rash and possible other autoimmune conditions that have not been verified yet if it's drug-related. All symptoms are since being on Entyvio. I'm so glad that I followed my instincts and not the drug's/Dr. Hoping for some better options that are safer for all of us!"

• Sti...
• Taken for 1 to 6 months
• November 16, 2016

For Ulcerative Colitis "After being allergic to all mesalamine drugs, Remicade, and built up antibodies against Humira, I was hopeful after my 4th treatment that I was finally in remission. Then, the morning of my 5th treatment, I go into the doctor's office. About 15 minutes after my IV started, I began to feel really lightheaded. I had a tight chest, and my whole body felt heavy. This out-of-body feeling came over me, and I was fixated on one spot of the room. Next thing I know, I wake up to EMTs over me saying I had unresponsive pupils with hives. They said I was unresponsive to everyone around. I don't remember anything else until I got to the ER. If you start to feel dizzy, tell the nurse right away! Good luck to everyone."

• Sha...
• Taken for 1 to 6 months
• April 26, 2023

For Crohn's Disease "Entyvio has not improved my symptoms and is a really harsh medication. I am having serious side effects, including high blood pressure, blurred vision, back and throat pain, confusion and inability to concentrate, rash on my face, fatigue, and several others. I would not recommend this drug to anyone. I am meeting with my doctor tomorrow to discuss alternative treatment."

• Tra...
• Taken for 1 to 2 years
• September 9, 2023

"Entyvio has changed my life, so please understand that any of my side effects or experiences are 100% worth it for me. I have had this disease my whole life. I was finally diagnosed at 25. I’ve had on-and-off bouts of active, severe disease and long stretches of remission. In 2021, I had the absolute worst flare of disease in my life. I was severely anemic, I could not function due to weakness, diarrhea, and pain. I’m 55 and work hard to not let my health rule my life, but I felt like I was dying. I didn’t want to start a med like Entyvio because I figured I would need to stay on it forever if I did. I had some long conversations and decided it was the best option. I hate the steroids, and I was really too sick to decline the new meds. Within three infusions, I was so much better. I have continued to improve. My side effects are this: flushed skin and rash 1-2 hours after my appointment, I take Benadryl. Headache, body pain, gas, bloating, exhaustion for 48 hours. Entirely worth it."

• Deb...
• Taken for 1 to 6 months
• September 25, 2021

For Ulcerative Colitis "Had serum sickness on Remicade due to an extended gap in treatment, after failed treatment to conventional therapy. Rash and fever to Humira. I did very well on SYMPHONI. But... insurance refused to pay for the monthly injections (Medicare/supplement) 3 doses in. So I had fatigue, hot flashes, minimal joint pain. Good results so far. I don't like going to the office for infusions when self-injection was going well. The company that produces this drug refused financial assistance. I retired from nursing after 46 years in a hospital setting."

• sue...
• Taken for 1 to 2 years
• July 26, 2025

For Ulcerative Colitis "Started Entyvio about a year and a half ago after I started getting horrible site reactions with Humira. I've had UC for 35 years. The Entyvio worked pretty well at first but with pretty bad fatigue and fogginess. Started getting a sporadic rash on my legs about 3 months ago. Getting ready to do blood work, stool studies, and another colonoscopy before switching to either Tremfya or Skyrizi. Doctor thinks the Entyvio is no longer controlling the UC, which has actually spread and is now considered pancolitis and has also moved up to my stomach esophageal area. I'm just so tired at this point and trying to remain positive that something will control the disease this soon."