Upadacitinib User Reviews & Ratings (Page 4)

• Joe...
• Taken for 1 to 6 months
• July 17, 2023

For Ankylosing Spondylitis "I have been on Rinvoq for 5 months. I noticed relief as soon as 4 weeks on this medication and I have continued to slowly get better and better. I'm hoping and praying it continues to work for me. My only complaint is a lot of depression, which is something I have never experienced in my whole life and I am 58 years old, so I'm certain it is Rinvoq. The only reason I have been determined to tolerate it is because I have gotten such good relief from the symptoms of ankylosing spondylitis."

• Anonymous
• Taken for 1 to 2 years
• May 10, 2023

For Rheumatoid Arthritis "Rinvoq is a life-changing medication. I have had RA for 31 years. I have been on every treatment available, but none gave me the relief this one pill has. Not any infusion or injection could produce the life this has given me back. No more morning stiffness, no more swollen joints, no more nodules developing on my hands or wrists. I highly recommend this treatment for those who are struggling."

• gam...
• Taken for 1 to 2 years
• October 30, 2024

For Ulcerative Colitis "39-year-old man. I was in a flare for over 3 years, and after taking every infusion available to me, I met with the surgeons to remove my bowel and have a bag fitted until I started Rinvoq. Complete turnaround, and now in remission (confirmed by biopsy) over a year. No side effects for me. Found it best to take before bedtime. Changed my life, but I'm hoping to be drug-free by 2025."

• Eva...
• Taken for 1 to 2 years
• November 3, 2021

For Rheumatoid Arthritis "I was using Plaquenil alone, then they added methotrexate, but it gave me headaches. So they eliminated it for sulfasalazine. It makes it less painful. But the doctor said I better use Rinvoq. I have been taking Rinvoq for a year now with Plaquenil and sulfasalazine. This addition makes me feel like I'm gaining my normal life back. The problem is that I started to have continuous UTI infections in the last 8 months. It is very painful. So I am considering changing meds."

• Jhu...
• Taken for 1 to 6 months
• May 2, 2023

For Atopic Dermatitis "This drug is an absolute lifesaver! Prior to taking it, I had no quality of life. I had severe itching, which resulted in approximately 3 hours of sleep a night. The itching was driving me insane to the point it seemed too hard. No medications, creams, or lotions worked. I was using a fork to scratch my skin as my nails couldn't relieve the itch. Within about 4 weeks after starting Rinvoq, I started getting significant relief. I have been on it for 6 months, and the itch issue is 100% gone. The horrendous eczema on my hands that was cracked and bleeding has cleared up as well, and an added bonus is I was spontaneously bruising very significantly. I could be sitting, watching TV, or sleeping at night, and I would be covered daily in severe large purple bruises on my body and face. I had no trauma to my body, but they spontaneously appeared. I looked like I had been in a bad accident when I was doing nothing to warrant bruising. They have progressively improved to only a few bruises."

• Rob...
• Taken for 1 to 6 months
• October 21, 2021

For Rheumatoid Arthritis "I have severe chronic RA and was diagnosed when I was 30 years old. I have suffered with this disease for 20 years. I'm amazed! I just can't believe the difference this medication has made. I've been on a 4-week trial and after 2 weeks, I have not had one flare. I can move my wrists freely and my knuckles and fingers are pain-free. So far, I haven't noticed any side effects. I am also taking methotrexate in conjunction with Rinvoq once a week. I find taking Rinvoq daily is a big chore and would like to have it in a weekly or monthly dose!"

• Nig...
• Taken for 1 to 6 months
• June 3, 2023

For Rheumatoid Arthritis "Many failed attempts from over six drugs for my RA, from oral to self-injections paired with methotrexate injections. I was put on Rinvoq in February 2023. Over time, headaches began, and I noticed elevated blood pressure. My PCP would tell me it's my OSA (obstructive sleep apnea). A couple of months later, the headaches and full-body pain became excruciating. Nothing I took would help. My blood pressure would not go down and even reached as high as 190/104. I also experienced a fast heartbeat. I was a miserable soul and wanted to dig a hole and jump in. An ER visit did nothing to alleviate my symptoms. I finally had to figure this out for myself. I decided to stop taking Rinvoq for a couple of days to see what would happen. I noticed a little improvement after day three, so I continued not taking it. I flushed the medication out with nothing but water. By day five, I felt so much better, and one week later, everything had stopped. All I was going through were my normal day-to-day struggles from RA, osteoarthritis, and fibromyalgia."

• AxP...
• Taken for less than 1 month
• November 20, 2023

For Ankylosing Spondylitis "Within one day, I felt less pain and less stiffness. I can finally walk, and walking the stairs and standing up from a chair is much easier now! It works really fast. Before starting Rinvoq, I had a huge flare-up of AS and Crohn's disease (IBD). I could barely walk. Do others also have mood drops after taking this med? Feeling jittery, sad, almost depressed. I tapered down my dosage to one pill every two days to measure the side effects. Both times, my mood dropped. If it continues, I'll have to switch to another drug. Depression is a no-go for me."

• meg...
• Taken for 1 to 2 years
• August 19, 2021

For Rheumatoid Arthritis "I have been on Rinvoq for over a year. I previously tried Xeljanz and Olumiant. I have had many problems with dizziness and vertigo. Has anyone else experienced these problems while on this class of drugs? I would appreciate any information on this debilitating problem. Thanks."

• jam...
• Taken for less than 1 month
• September 14, 2022

For Rheumatoid Arthritis "I started this medicine after Enbrel and Humira failed me. Within a week of taking this medicine, I got shingles, rashes, mouth sores, awful stomach pain, back pain, and my heart was racing at 120 beats a minute. I tried to reason with my Dr, she said the benefits outweigh the risks. I say not, so I am quitting the med and hoping for the best."

• Oli...
• Taken for 2 to 5 years
• September 6, 2022

For Rheumatoid Arthritis "I started this medication 5 yrs after my RA diagnosis. Went through and failed all the others from methotrexate to Humira and Enbrel. I was a shell of my former self when I started Rinvoq. Much to my surprise, it worked immediately. With it came abdominal pain and gastric distress, several bouts of diverticulitis, UTI, and kidney infection. That being said, I went from immobile to mobile, which is a huge consideration. Due to the many infections, my rheumatologist recommended 3 x a week dosing, 15 mg. Much to my dismay, the infections continue. I was just off this med entirely for 6 weeks and returned due to the onset of pain and stiffness in my joints. I do plan on using half my prescribed dose from here on out. If infections persist, I'm gonna have to call it quits. There are side effects to antibiotics (Levofloxacin), such as spontaneous tendon rupture, that pale in comparison to my worst RA day. Do my best to eat right, stay in a normal weight range, and walk, and hope for the best."

• Sti...
• Taken for 1 to 6 months
• November 3, 2022

For Atopic Dermatitis "Severe atopic dermatitis popped up out of nowhere a year ago (reaction to 3rd Pfizer vaccine remains suspect). Outbreak had started to taper off at the beginning of 15 mg/day Rinvoq regimen. Continued progress through 2.5 months when I got a 4th Pfizer vaccine, at which point itchy spots started appearing again. Still, nothing like my initial outbreak but the jury's still out as to Rinvoq's effectiveness after 3.5 months. 68-year-old male. No side effects."

• joh...
• Taken for 1 to 6 months
• April 14, 2023

For Atopic Dermatitis "I had uncontrollable itching and tried all sorts of things to help and was finally prescribed Rinvoq. With no insurance, I was able to sign up for a free Rx. Rinvoq gave me my life back. The itching was gone!!! Then I started seeing the side effects of shortness of breath, my legs breaking out in what appeared to be massive acne, and I am getting headaches and a slight cough. I have taken it for 3 months and a little of the itching has come back, I am definitely looking for an alternative."

• Dav...
• Taken for 2 to 5 years
• August 24, 2022

For Rheumatoid Arthritis "Five years ago, I got diagnosed with rheumatoid arthritis. I was 32 years old, and it was crippling. Considering my second son was just born, it was not good timing. I tried every medicine. I felt like a guinea pig. Nothing really worked. My rheumatologist was getting a little desperate, and that scared me for sure. I tried all types of diets, the carnivore diet definitely worked the best, and getting rid of carbs was big. Some days, I still could barely walk. Rinvoq was amazing, I've been on it for about two years, and I'm 92% better. I can't say much about many side effects. I have an eczema sun rash, but nobody really knows if that's from the medicine. Small price to pay if it is. I wish I knew more diet stuff earlier. The best for me was the carnivore diet (no carbs), but I didn't really try the full vegan diet long enough to tell. In any case, diets really help, but they have to be strict! Overall, Rinvoq was the game changer. Hopefully, no long-term side effects."

• Tom...
• Taken for 6 months to 1 year
• January 6, 2024

For Atopic Dermatitis "It's not a miracle cure like they say. I believe there is a 60% improvement in my eczema after being on it for about half a year. No side effects that I've noticed, which is good. Overall, I suppose it's better than nothing, but it's just a little sad to realize there is still no medication that can cure eczema by at least 90% or more, though I realize that biologics work almost fully for some people. I'm just not one of them."

• Jen...
• Taken for 1 to 2 years
• January 4, 2024

For Rheumatoid Arthritis "Two and a half years ago, I was diagnosed with RA. Over a little more than a year and a half ago, the doctor tried methotrexate, Humira (2 shots monthly), and Inflectra infusions (every 2 months). I would improve a bit early on (from bad pain and stiffness) after the treatments, then I’d fall apart. Flare-ups, allergic reactions, bad pain & sadness would creep in. Within 2 days of taking Rinvoq, I felt great! I’m sorry to read the other reviews, as my experience has been very positive. Any infections I’ve gotten can be explained - and stopping Rinvoq for a few days helps my immune system catch up. Knock on wood it keeps working for me! I respond well to taking Rinvoq every day! Thank you for inventing and investing in Rinvoq!!"

• UCo...
• Taken for less than 1 month
• March 18, 2023

For Ulcerative Colitis "I was given Rinvoq for the treatment of my ulcerative colitis by my gastroenterologist. Unfortunately, after only my first induction dose of 45 mg, I suffered an allergic reaction with the following symptoms: headache, constricted nasal passages, difficulty breathing, pain in my upper back, pain in my lungs, my lungs felt like they were burning, lightheadedness, blurry/fuzzy vision, numbness in my left arm, pain in my left arm, cold sweats, and pain in my abdomen. Ended in the ER, and the ER doctor said to stop taking this medication."

• Pat...
• Taken for 1 to 6 months
• May 22, 2023

For Psoriatic Arthritis "I’ve been searching for relief of psoriatic arthritis in fingers, wrists, knees, ankles, toes, neck, and spine, along with major scalp inflammation and intense itching and burning. After 9 weeks of the 15 mg dose, my arthritis has improved by about 30%. No adverse side effects. This Rinvoq is the most helpful of all that I’ve tried."

• Sue...
• Taken for 6 months to 1 year
• April 21, 2023

For Atopic Dermatitis "I've been taking Rinvoq for almost a year now and had to increase from 15 mg to 30 mg because the itching and inflammation came back after about 20 hours of taking it. I've gained almost 15 kg!!! and I can't get it off without starving myself. The cholesterol and kidney values are also noticeable but not yet worrying. All in all, a completely new life and wouldn't want to have to vegetate without this effect anymore!"

• Kch...
• Taken for 1 to 6 months
• July 6, 2023

For Rheumatoid Arthritis "I have been on Rinvoq for 1 month. I had my labs drawn today and my results of my CBC are alarming! Low WBC, RBC, Platelets and more. I'm stopping this med and calling my Dr first thing in the morning."

• Tad...
• Taken for 1 to 2 years
• February 2, 2024

For Rheumatoid Arthritis "Rinvoq has been the only medicine that has helped, minus steroids, in my 3-year battle with severe RA. It has come with its fair share of side effects, with the most prominent one being dizziness and vertigo spells lasting long periods of time daily. Mild cases of heart discomfort and acne. It's hard to weigh in if it's worth it, as it's the only medication, minus steroids, as mentioned before, that has worked. I've tried just about all besides one more, so it's alarming that I'm on my last two options, so I'm continuing for now."

• Yog...
• Taken for 1 to 6 months
• July 21, 2023

For Ankylosing Spondylitis "I have HLA-B27 marker. Been on Sulfasalazine, Enbrel, and Cimzia during the last 15 years. During the last few years, the pain had become unbearable. My rheumatologist suggested RINVOQ. Been on it for the last four weeks. Pain has now become bearable and feel much, much better the way I used to feel a few years back. I do not know of its long-term impact, but am happy with it now."

• Cam...
• Taken for 1 to 6 months
• March 19, 2024

For Ankylosing Spondylitis "I have gotten sick regularly with this drug. It helped my arthritis, but I stopped taking it for 3 days when I started to get a fever and night sweats. After three days of stopping the medication, my arthritis came back with a vengeance, and I started taking it again even though I was sick. I still have back pain and joint pain."

• Rob...
• Taken for 1 to 6 months
• June 29, 2023

For Ankylosing Spondylitis "I was on TNF blockers, and after a while, they stopped working. I switched to Rinvoq, and I've been much happier. I still have stiffness and pain, but on a way smaller scale than before. It went from an 8 down to a 4, which makes me happy. I did have a shingles problem which is clearing up. I also had a plugged tear duct problem. I had to have it drained four times. The other thing is I'm really tired, but I'm not sure if it's the medication or stress from work. I've been slowly losing weight, but I'm able to walk and exercise, so I think it's from that more than the medication. Overall, I'm really happy with it."

• Anonymous
• Taken for 1 to 2 years
• July 1, 2022

For Rheumatoid Arthritis "Been on Rinvoq for nearly two years. I started at 67 when I couldn't walk from bad rheumatoid arthritis. Both knees had cysts and shooting pain from a fall off my bike several years ago woke me up at night. Rinvoq worked miracles for me. Started gardening and cooking again. Only take every other day as I am about 120 lbs, 5 ft 6 inches tall. Also, as an elderly person, meds don't metabolize as quickly. However, I do stop taking it whenever I feel a scratchy throat or run down from cold symptoms. Also stop if I get a mouth sore from biting myself when chewing."