Upadacitinib User Reviews & Ratings (Page 3)

• Ton...
• Taken for 1 to 6 months
• December 19, 2021

For Rheumatoid Arthritis "Developed RA in April 2020. I'm a maintenance fitter, and it knocked me about terribly. The first doctor gave me Celebrex, which basically did nothing. Went to doctor No. 2, and he diagnosed the RA properly. Put me straight on to prednisolone 25 mg and booked me in with a specialist. I felt 20 years younger within a few days. I began taking Methotrexate and cutting back 5 mg of the prednisolone every 6 weeks. The pain and swelling started increasing, so I stopped reducing the steroids. After 3 months, he put me on Plaquenil, and I resumed cutting back on the prednisolone. It got to a point where the pain was controllable after a few hours each day. I'm sero positive, so there are good days and not so good days. My job is quite physical generally, so the RA had been quite debilitating at times. By about May this year, things weren't great again, so the doc suggested Rinvoq as an alternative. I've been on it for 2.5 months. I'm loving the results. No real side effects yet."

• Bre...
• Taken for 1 to 2 years
• October 10, 2021

For Rheumatoid Arthritis "I have been on RINVOQ for about a year and a half. It was working great for the pain and stiffness, and then I started getting short of breath and a cough. It wasn’t too bad at first, but it has progressively gotten so bad that I cough all day, and the least little thing I do, I’m short of breath. I have stopped taking the medication, but I have still not improved. Does anyone know how long it takes for this medication to leave your system?"

• Mir...
• Taken for 1 to 6 months
• January 5, 2023

For Atopic Dermatitis "I have lived with severe atopic dermatitis for my entire life (62). The last decade has been debilitating despite cyclosporine, CellCept, methotrexate, Imuran, buckets of topical steroids, and prednisone. Dupixent helped a lot but still severe. I just started Rinvoq 15 mg 1 month ago, and my severe rash, itch, and pain have 75% cleared. The physical and psychological effects of decades of rash and relentless itch are indescribable. I am jumping for joy and have not felt this good for pretty much my entire life. I am hopeful for the future. Side effects are simply some acne, which I can manage with over-the-counter creams and cleansers."

• Nev...
• Taken for 1 to 6 months
• August 28, 2022

For Rheumatoid Arthritis "I was on this medication for several months and had a stroke at 42! I stayed in the hospital for over a month and had over 13 doctors during this time. 11 out of 13 doctors said that Covid shots and this medication were a bomb waiting to happen! Causing a major stroke! I had very little signs and symptoms but enough to know something wasn’t good. I suffered with dizziness, headaches, chest pain, shortness of breath, and all of this made me always think I had Covid! The same symptoms for Covid are pretty much the same symptoms for every medication in the world that you take! It’s really hard to determine what symptom goes with what diagnosis this day and age! Don’t wait until it’s too late, just stop taking this medication and try something else. It’s not worth it!"

• Pau...
• Taken for 2 to 5 years
• July 2, 2023

For Ulcerative Colitis "This is an amazing drug that I have now used for about two years. My UC was so bad, I could not leave the house. I have tried all the others with no success, including Entyvio and Stelar. I have my life back! The only side effects are folliculitis on the scalp and possible weight gain. For me, it's a godsend. I'm on the maintenance dose of 30 mg."

• Cha...
• Taken for 2 to 5 years
• December 23, 2021

For Rheumatoid Arthritis "I was in a clinical trial for Rinvoq for five (5) years. Never again. In September 2021, the FDA issued a 'boxed' warning (the most serious kind of warning) to be put on Rinvoq regarding the possibility of heart attack and stroke. The research lab conducting the study never informed me of this, and they had to have known because the FDA does not issue boxed warnings overnight. Thank God the trial ended in October 2021. In addition, the research lab did not tell me about side effects such as horrible acne with large whiteheads on my face and back pain. I would not sign up for a clinical trial again because I would not know if they were telling the whole truth and nothing but the truth. No more Rinvoq for me. The research lab also told me that Rinvoq would be available at the end of the 5-year trial if I wanted to continue taking it (I don't). Yes, available at the retail cost of $5,969.00 per month. Yes, per month. I don't know anyone who can afford that except the very wealthy."

• Jul...
• Taken for 6 months to 1 year
• November 17, 2021

For Rheumatoid Arthritis "Been on Rinvoq about 8 months. Shortness of breath couldn't walk to the mailbox. All heart tests negative. Sitting here and realized these symptoms coordinated with taking this drug. Starting tomorrow, no more Rinvoq."

• Col...
• Taken for 1 to 2 years
• November 28, 2023

For Rheumatoid Arthritis "I have been using Rinvoq now for almost 2 years. I have absolutely no side effects. I feel normal again. I am 60 years old and I work full time. When I was diagnosed with RA, I could barely walk or get out of bed."

• BEW...
• Taken for 1 to 6 months
• April 22, 2023

For Ankylosing Spondylitis "I have tried Enbrel, Humira, methotrexate, etc., and finally Rinvoq. At first, I had a positive response and started to feel much better, but then after 8-10 weeks, the 3-4+ pitting edema became unbearable, and the shortness of breath was downright frightening, coupled with total exhaustion. I was unable to maintain my daily routine and functioning. I had all of the signs and symptoms of congestive heart failure. It finally got to the point that I had such labored breathing my cardiologist and others were very concerned - and this was two weeks post-stopping Rinvoq. My afib was having a field day, and I felt awful all of the time. At this point, I am three weeks out from stopping the Rinvoq and am wondering how long this will continue until my system has cleared this medication. It is black-boxed for cardiac, amongst other things, and this warning should be seriously taken under consideration before starting this medication. I felt like I was dying - think long and hard before you take it."

• Mom...
• Taken for 1 to 6 months
• January 14, 2021

For Rheumatoid Arthritis "I have tried many meds for RA. Was very successful with Xeljanz but had continual sinusitis. Now Rinvoq is not as successful for pain/RA, but I get less sinusitis. Also developed very oily skin and acne about my neck, face, and shoulders. I am 58 and on HRT as well and MRX 10 mg."

• Anonymous
• Taken for 1 to 6 months
• January 4, 2023

For Ulcerative Colitis "Been on medication for 2 months and going on a maintenance dose now. It has so far kept my UC under control after an 8-month flare-up. However, the last 3 weeks I have been suffering with dermatitis on my face, neck, and chest. I’m struggling to get rid of it with topical treatment and don’t know if it's caused by Rinvoq. Also, I feel like I have unexplained weight gain but not sure yet if it’s caused by Rinvoq."

• Lua...
• Taken for less than 1 month
• September 7, 2020

For Rheumatoid Arthritis "I have taken methotrexate, prednisone, Humira, and Xeljanz for rheumatoid arthritis. Due to inflammation, I have been put on Rinvoq for 2 weeks now. I’m nauseous, have dry eyes, blurred vision, and fibromyalgia. I also have Type 1 diabetes, pancreatitis on Fiasp/Toujeo, and ulcerative colitis."

• bar...
• Taken for 2 to 5 years
• March 7, 2022

For Rheumatoid Arthritis "I have had RA for 3 years, nothing worked except Rinvoq. I was almost normal, almost no pain, and could do normal activities. I am a 61-year-old woman. I have always had a cough, but it worsened with Rinvoq, but I continued with the drug. Went for a routine lung test, and they found fatty tissue on my lungs, did more X-rays and CT scans. Now they have found that my lymph nodes are abnormal, going for a biopsy next week. Seems this could be a side effect of Rinvoq, now I am scared."

• Mol...
• December 26, 2022

For Atopic Dermatitis "Been taking this Rinvoq for 3 weeks, and it is nothing short of a miracle. Went from being so itchy that I couldn’t sleep to having everything cleared in just a few days. No more itching. I haven’t felt this good in years."

• ess...
• Taken for 1 to 6 months
• November 27, 2022

For Atopic Dermatitis "I've only been on Rinvoq for a month to treat atopic dermatitis, but am calling my dermatologist tomorrow. The dermatitis has cleared up, but at the expense of severe nausea, headaches, chills, cold sores, and acne. I'm typically very active with running, biking, and hiking, but in the last month of taking this, I feel so bad all I want to do is sleep. In Rinvoq's defense, my body does not react well to most drugs, so maybe it is just me, but I've never had this bad of a reaction to any drug."

• Sci...
• Taken for 1 to 6 months
• July 14, 2022

For Ulcerative Colitis "So far, so good - it's keeping my UC in check after about 1 month of taking 3x/day. I will be dropping down to the maintenance dose after 2 months, assuming all continues to go well. The only side effect has been some pretty noticeable fatigue from time to time."

• Kat...
• October 12, 2023

For Rheumatoid Arthritis "I have had RA for 10 years. I was on a new drug every 6 months because nothing was working. I have had countless surgeries to remove nodules on my hands, elbows, and arms. I have been hospitalized twice for acute pain. I have been diagnosed with a severe and aggressive form of RA. I have been on Rinvoq for nine months. The drug started working right away and I am currently in remission. I used to take Prednisone like it was candy. In 9 months, I have taken 2 Prednisones. My quality of life went from poor to fantastic. This has been a miracle drug for me."

• Dec...
• Taken for 1 to 2 years
• November 16, 2023

For Rheumatoid Arthritis "At one point I had to use a walker and wheelchair. My mobility was so bad I sold my drums and boat because I couldn't use them. I started Rinvoq and after three months, I was doing yard work and almost anything I wanted to do. It's been almost two years now and I'm playing drums again, cutting trees, yard work, cement, and pavers. No side effects, no issues. Thank you, Rinvoq."

• San...
• Taken for 6 months to 1 year
• September 16, 2021

For Rheumatoid Arthritis "I have been taking Rinvoq for 11.5 months now. This drug has changed my life. I noticed a big improvement in my pain symptoms about four weeks in. I am 95% pain-free, and most days I forget I have RA. I do get flares and bad pain every once in a while. The cons of this drug are that it gives me bad fatigue. The fatigue was very disruptive to my life for the first 6-7 months. I have a constant lingering feeling that I am getting sick but never actually get sick. I have also started breaking out around my chin and forehead. I am in my 20s, and during puberty, I did not suffer from any acne. Overall, this is a great drug for managing my RA and has given me a lot of my life back."

• RBM...
• Taken for 1 to 6 months
• May 24, 2022

For Rheumatoid Arthritis "I was taking methotrexate ($67 a month) for 14 years. I still had a little pain and inflammation in my joints. My rheumatologist prescribed Rinvoq ($6,300 a month). I took it for 3 months. The first 3 weeks, it worked because I still had methotrexate in my body, but after that, my pain came back a lot stronger! Finally, I went back to methotrexate, but for some reason, methotrexate did not work as good anymore as it worked before I started taking Rinvoq. I am totally disabled to the point that I can’t even do simple things I used to do before I took Rinvoq. I think Rinvoq changed something in my body that is not repairable. This is a very bad drug."

• mis...
• Taken for 6 months to 1 year
• September 7, 2021

For Rheumatoid Arthritis "I have been on Rinvoq for about 9 months on and off. I have dry eyes, constant runny nose. Now I have pins and needles in my hands 90% of the time, ulcers in my mouth, and when I don't take the Rinvoq for a week or more, the pins and needles are rare. I think I'm gonna stop it before it stops me."

• Col...
• November 4, 2023

For Rheumatoid Arthritis "My improvement was both astonishing and quick. Within 4 days of taking Rinvoq, the 'me' I was before RA was coming back. As seven medicines had already failed me, I began Rinvoq, as usual, optimistic but fatalistic. Even if it worked, my RA history made me only cautiously optimistic—one previous Rx had worked but sent my liver enzymes high, forcing me to stop. So, when I started to feel immensely better by that first weekend, with more energy, with pain & swelling reduced to almost nothing, I was incredulous. I could not believe the difference. Five months later, I am a huge fan. My energy is almost all back (hurray!), I've had only one very, very minor flare, and after two blood tests my ALT remains only mildly elevated. So, yes, I am an enthusiastic fan with a close-to-normal schedule of life. I take a daily 15mg pill, easy to do. For me, this medicine has results that I'd lost hope for. I have 'me' back."

• Liz...
• Taken for 1 to 2 years
• July 4, 2022

For Rheumatoid Arthritis "I have RA and Ménière’s (inner ear problem). Rinvoq worsens my inner ear problem, causing increased vertigo. Stopped Rinvoq temporarily for another reason. Vertigo episodes disappeared! Restarted Rinvoq: vertigo returned a week later. Stopped the Rinvoq for 3 weeks again: vertigo disappeared. Restarted Rinvoq: vertigo returned. When I take Rinvoq every other day instead of daily, vertigo episodes are +/- one per month. When I take Rinvoq daily, vertigo episodes are 1 or 2 per day. Rinvoq exacerbates my inner ear problem, making Ménière’s more difficult to control, resulting in more frequent vertigo. Several reviews mention vertigo and dizziness on Rinvoq, but vertigo doesn’t show up in the official side effects list. If you’re having vertigo, spinning sensation, dizziness on Rinvoq, please post here, tell MD, and tell specialty pharmacy. They won’t list it as an uncommon side effect if they don’t know about it. They won’t know about it unless we tell them."

• Swe...
• Taken for 1 to 6 months
• June 7, 2023

For Ulcerative Colitis "I have been suffering from colitis for the last 7 years. I have been using Rinvoq for the last 2 months. It’s working well for me, but I have had a large hair loss. Don't know if it's because of Rinvoq. However, it looks like my life is back, thanks to Rinvoq."

• J-S...
• Taken for 1 to 6 months
• November 8, 2023

For Ulcerative Colitis "My body has been rejecting biological meds, so this is my first time trying this. I'm on 45mg. I'm having crazy side effects like throat dryness and skin itching and bubbling with open sores. But I will start maintenance dose in Dec, 30mg, and the doctor says side effects will ease up. First time in six years, body inflammation is almost zero. I hope this will work long term, like 20+ years for me."