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Triamcinolone for Osteoarthritis User Reviews

Brand names: Kenalog-40, Zilretta, Kenalog-10, Aristospan Clinacort Aristospan Intra-Articular Aristospan Intralesional

Rating: 5.7

Triamcinolone has an average rating of 5.7 out of 10 from a total of 86 reviews for the treatment of osteoarthritis. 44% of reviewers reported a positive experience, while 43% reported a negative experience.

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Reviews for Triamcinolone

Commonly mentioned side effects
  • Kat...
  • Taken for less than 1 month
  • October 27, 2020

"This is the first and last time using this injection. I'm 8 weeks in and still having panic attacks, insomnia, increased hunger, and anxiety. How long does this last? Please avoid at all costs, you will regret it."

1 / 10
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  • ATa...
  • Taken for 1 to 2 years
  • April 14, 2021

"For years, my pain management doctor tried different medicines, but all worked about 1 to 2 weeks. When a new pain management doctor entered the practice, she suggested that we try Zilretta. Pain was almost immediately gone, and it lasts for 2 months. Then I can manage the pain with Aleve for the next month. Zilretta has changed my life. I have been having the injections in my right knee for almost 2 years now. Have noticed no side effects."

9 / 10
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  • Swa...
  • November 10, 2020

"I am in the last stages of osteoarthritis in both knees. I’m pretty young to have knees as bad as I do (so my doctor says). I’m 52 and have been fighting osteoarthritis for 12 years now. I had Zilretta injections in January 2020, and it was amazing for the pain. I was pain-free for 3 months. My range of motion stayed the same, but I had no pain! The only negative thing is when the injections wore off, I had no warning of the pain coming back, it came back with a vengeance. I scheduled knee surgery for August and canceled because of the coronavirus. So today, I had Zilretta injections again to buy time until I feel safe to have surgery! These injections have been the only thing that works for me, and I’m so grateful to be pain-free even if it is only for 3 months!"

10 / 10
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Frequently asked questions

  • Nan...
  • Taken for less than 1 month
  • October 7, 2022

"I had a Kenalog 80 injection in my cervical spine on 7/29/22. Thirteen days later, severe internal shakiness and tremor (which is the worst side effect of all, in my opinion). It is worse than anxiety, and it is never-ending all day long. Abnormal uterine bleeding for six weeks until the gyno put me on meds to stop the bleeding because I became anemic and had to have an iron infusion. Palpitations, shortness of breath, terrible indigestion, my legs and arms feel heavy all the time, multiple daily hot flushes, and I ended up in the ER. Oh, did I mention the internal shaking that is relentless, and Xanax didn't even help them? It is 2 1/2 months since the injection, and the side effects are still awful. I had to take time off of work. I've seen eight different doctors to no avail. No one can help. Beware!!"

1 / 10
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31 Report
  • DJA...
  • Taken for 1 to 6 months
  • November 3, 2019

"I have tried all available types of injections for my right knee, and I have had less and less effectiveness with each injection. Zilretta has been a miracle drug, as it has given me pain and swelling relief for two months. I am very active. I jog about 15-20 miles a week and walk about another 5 miles per week. Before Zilretta, I did it with pain and a limp - not now!"

10 / 10
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  • Kat...
  • Taken for less than 1 month
  • October 6, 2018

"One day I was hobbling at work, walking with a cane. I was done! Some days I couldn’t get up out of a chair. My Dr. told me about Zilretta injections for both my knees. I was shocked my insurance covered it! Only $50 for both knees. Had both knees drained and injections with Zilretta. WOW! After 2 days of ice, I stood up and walked normally for the first time in 12 years, I had no knee pain at all. I had little to no swelling from the knees down. I have told everyone I know about Zilretta! So happy to be pain-free! Thank you!"

10 / 10
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  • Sca...
  • Taken for 1 to 6 months
  • December 9, 2018

"Do not get this injection! I got mine about 6 1/2 weeks ago. The first week was okay, no side effects, but no pain relief either. Side effects for me started at week 2 and are still going. Burning mouth/throat, worse anxiety than I already had, extreme nausea, no appetite. I’ve lost 8 lbs, and I cannot afford to lose weight. I’m terrified how long this will go on."

1 / 10
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More FAQ

  • WOR...
  • Taken for less than 1 month
  • November 2, 2021

"I should have read the reviews before getting an injection of Kenalog in my knee. Almost immediately, I started feeling dizzy, and as the day and night went on, my heart started racing. I haven’t slept for one minute. I have extreme anxiety, and my blood pressure shot up to 159/95 with a pulse of 95, and that is even on my blood pressure medicine. I had the worst heartburn and just feel dread. I am hoping these side effects subside over the next few days, but the reviews say not. Also, it has made my asthma a lot worse over the last 24 hours. This is the second injection I have gotten, and I said I would never do it again, but this time I mean it. It never did help my pain, what a waste."

1 / 10
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32 Report
  • Anonymous
  • Taken for 1 to 6 months
  • June 24, 2019

"Since getting an injection of Zilretta after years of cortisone injections for bone on bone in my knees, my worse knee has gotten unbearable. I now not only have knee pain, but it feels like a rubber band breaking behind my kneecap and excruciating nerve pain down my whole left leg, even while sleeping. I don't recommend getting this shot. Because of it, I now will have to have my knee replaced sooner rather than later."

2 / 10
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43 Report
  • Anonymous
  • March 26, 2019

"I have bone on bone in both knees and have been in horrible pain for about a year. I have had cortisone injections in the past, with the last one only getting relief for a week. I was completely at my wits' end. I am only 58 years old and am trying to hold off on knee replacement surgery for as long as possible. My prayers have been answered with Zilretta, I had an injection in both knees 8 days ago and I feel like a new person. I pray the relief continues. I would recommend this to everyone suffering from knee pain."

9 / 10
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40 Report
  • Sus...
  • Taken for 6 months to 1 year
  • September 13, 2018

"I have had Zilretta injections in both of my knees. It is absolutely fantastic! I was pain-free the 1st day after my injection. I did not have any side effects. I can do things I haven't been able to do for years. Going up and down stairs is so much easier now. I can stand in one place for an extended period of time. I can kneel on the floor and play with my grandkids. I feel like a new person being pain-free. I would recommend anyone with osteoarthritis try Zilretta."

10 / 10
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36 Report
  • nuk...
  • Taken for 1 to 6 months
  • January 23, 2019

"I've had medial left knee pain for a while and tried different avenues of pain management, including hyaluronic acid injections. Zilretta is awesome! It took a good week for it to kick in, but I am now at one month, and the pain has subsided immensely. No side effects at all. I'm very active and play a lot of pickleball, so I'm a true test to the effectiveness of this drug."

10 / 10
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33 Report
  • Hel...
  • Taken for less than 1 month
  • September 16, 2017

"Had an injection into my knee due to osteoarthritis. I am scheduled for knee replacement, but there is a 1-year wait for surgery. Before the injection, I could not sleep due to throbbing pain, and after the injection, this is gone. My overall pain is significantly reduced. I had no adverse reaction to the drug."

8 / 10
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36 Report
  • NeN...
  • Taken for 6 months to 1 year
  • May 3, 2019

"MAN!!! Where do I start? Both knees are shot, but I’m unable to do surgery at this time because of mother-in-law's broken hip and recent major surgery on my son, so we’re taking care of them. Zilretta is fantastic for my osteoarthritis, it works, and it lasts for about 3 months. I have been taking the injections for about 9 months. Before that, the doctor was doing steroid injections that lasted almost 2-3 weeks. Greatest product."

10 / 10
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29 Report
  • Tag...
  • Taken for 1 to 6 months
  • September 19, 2019

"I also have bone-on-bone in my knee. I was using cortisone injections, and then the doctor told me about Zilretta. I got the injection in May, and by August, it was wearing off. I am in more pain now than ever before. It felt great at first, but WOW. I do not recommend this."

2 / 10
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28 Report
  • Hav...
  • Taken for 6 months to 1 year
  • May 26, 2019

"The first set of injections kept me in pain and off of my feet for over a week. I've had to get the injections every 3 months instead of every 6 like my last medication. Every time it is the same thing, both knees end up swollen and painful for a week or longer. The effects of Zilretta are semi-beneficial for about 8 weeks. I've had a lot more pain, stiffness, and swelling in my knees since taking Zilretta. There are days that I can't fully straighten or bend my legs. The inflammation is bad, and my symptoms are becoming worse than they were before I started Zilretta. This is a serious concern. I'm glad that it is helping some people, but for me, the short 8 weeks of slight relief is not worth the pain and worsening of symptoms that I have for the rest of the time between injections."

4 / 10
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29 Report
  • Mar...
  • Taken for less than 1 month
  • February 6, 2019

"I've had every knee shot for knee osteoarthritis, with no results. I've had moderate to severe knee pain for five years. I had my left knee injected two weeks ago and got immediate results. Pain-free! Yesterday, I had my right knee injected with the same results. Zilretta is amazing! Curious to see how long the shots will last."

10 / 10
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28 Report
  • Sty...
  • September 2, 2015

"No one warned me that there were any side effects to worry about. I was given 2 injections into my left hip of Kenalog-40. Later, the first evening, my face was hot and turned scarlet red. The red swelling went into my right eye and felt like sand. Then I started getting dizzy. My blood pressure was off the charts, and my blood sugar doubled! I had to lay down, and all I did was sweat. I thought I was having a heart attack! The next day, the facial rash was better, but the dizziness turned into violent shaking! When sitting very still, it felt like my whole body was on top of a paint shaker. I got horrible diarrhea that lasted for days. My OLP flared into a bloody mess. It took 12 to 15 weeks to even feel kind of normal again."

2 / 10
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40 Report
  • M m...
  • Taken for 1 to 6 months
  • February 10, 2020

"I have had two shots of Zilretta in my right knee. The shot lasts exactly 90 days. About 48 hours after receiving this shot, all pain is gone, and I feel like I have a brand new knee. But I have to fight with my Federal Blue Cross Blue Shield to pay for this shot. It is a great shot if you can schedule the shot exactly every 90 days. The company that manufactures this drug offers no discounts and no coupons or financial help. Even with insurance, this shot costs 240 dollars."

10 / 10
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21 Report
  • Tci...
  • Taken for less than 1 month
  • March 12, 2022

"I had an injection of Kenalog 3 days ago in my left thumb joint at the base of my thumb. I am miserable, pain, swelling, redness up my arm, and burning itch and blisters. Some type of allergic reaction, which apparently is not common, however, I got this reaction. I’m scared since my symptoms are similar to a skin infection (cellulitis), so I just started antibiotics and an anti-inflammatory. Terrible drug. I was so happy to relieve my arthritis pain, and this has happened. How long until this drug is out of my system?"

1 / 10
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13 Report
  • Lov...
  • Taken for less than 1 month
  • January 10, 2019

"I am 74 years young, an active person. Had pain in my jaw for about three weeks, could hardly talk or eat. Thinking it was something awful, I went to the E.R., and the MD there ordered a CAT scan of the mandible, etc. Finally, the report came in as osteoarthritis of the jaw area and inflammation, etc. Well, I was given 2 injections: one of Toradol for pain and Kenalog for the inflammation. Amazingly, after about one hour, I felt much better. Hardly any pain. The doctor told me to see my own MD for follow-up and to take Aleve for pain until then. I will be making an appt. ASAP since I was good for three whole weeks, but now the pain is starting again. I don't want to take Aleve too much as it irritates the stomach and could be harmful if taken consistently. No side effects from either drug."

8 / 10
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20 Report
  • nee...
  • Taken for less than 1 month
  • June 14, 2022

"70 years, was given Kenalog-40/Lidocaine 10% injection in knee. 2 days later, stomach problems started; queasy, cramps, partial loss of appetite, burping constantly, and not feeling well. I am into a week since the injection. Called the doctor's office and was told this is one of the common side effects. Lasting time varies on individuals. Please be informed of side effects before receiving injections. I will not take it again; I will endure knee pain. I have stomach cramps all day/every day. Pray and hope side effects end soon. Please be informed about what a doctor is administering."

2 / 10
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12 Report
  • ano...
  • Taken for 6 months to 1 year
  • April 2, 2019

"I had high hopes for this injection after failed cortisone and other injections. I iced my knee several times a day. I have a bit of relief in my knee, but by the end of the day, I'm 'toast.' It has been one week since my injection. I'm glad others had success, however, it is not working for me."

3 / 10
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19 Report
  • Jil...
  • Taken for 1 to 6 months
  • May 12, 2018

"I got an injection in my right knee a month ago today (Dr. had a sample). I was a little worried about it containing steroids because I've previously had them worsen my mental health symptoms, but I didn't have too many problems with that this time. Of course, after the injection, my knee was sore and swollen, making it difficult to walk right for a few days. I noticed nasal congestion, which is one of the side effects. Since it's extended release, I expected the osteoarthritis pain and swelling in my knee to go down, at least a little bit over time. To date, it hasn't and has actually gotten worse. I've also noticed increased knee stiffness and leg spasms (feels like they're behind the knee cap) that I didn't have before. I was looking forward to this med providing much-needed relief, not causing issues. At this point, I'm not planning to get my left knee done. Just not the results I expected. Although I don't believe it's at all related, I will be fair and mention I also have fibromyalgia."

3 / 10
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26 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • June 6, 2019

"Some mild pain and inflammation relief, but that lasted just a little while. It's supposed to last a long time, but my knee is pretty much worse than before I started the Zilretta injection. I can't say if that's the natural progression or the cortisone sped it up. But I can say that the regular cortisone shot I got before Zilretta was way more effective. I would not recommend Zilretta."

3 / 10
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21 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.