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Ultram and Headaches: What Users Say

Headaches: mentioned by 12 users (5.2%)

Based on user experiences from 229 Ultram reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 8.7%
drowsiness 6.6%
withdrawal 6.6%
headaches 5.2%
constipation 2.6%
dizziness 2.6%
fatigue 2.6%
itching 2.6%
irritability 2.2%
sweating 2.2%

Reviews for Ultram

Commonly mentioned side effects
  • Mya...
  • March 27, 2008

For Pain "I have been diagnosed with fibromyalgia and osteoarthritis, so I am in fairly constant pain. Ultram has really been a lifesaver, allowing me to work and play. Headache is sometimes a problem, but I think almost always in combination with caffeine."

8 / 10
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147 Report
  • Reb...
  • Taken for less than 1 month
  • October 4, 2019

For Pain "Years ago, I used Ultram for migraines, and one day took more than 2 in a smaller period of time and had a seizure. Scariest thing ever. Thankfully, I had a great neurologist who knew it was this medication, and I stopped immediately. Never had another. The medicine was decent, though, while I had taken it, and it didn’t make me feel like I was taking a prescription pain reliever. (If anything, it has the feeling of too much caffeine.) Just be careful on dosage."

7 / 10
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27 Report
  • Maj...
  • July 9, 2015

For Pain "I just started this med yesterday for osteoarthritis and fibromyalgia. After reading the other comments, my experience is pretty normal. I'm itching like crazy, had a bad night-no rest, nausea, and mild headache. With all those side effects, it appears to have knocked off the edge of the pain. I will continue using it for a few days if I can handle the itching. I want to give it some time because I cannot use narcotics. I end up in the hospital with dehydration from vomiting when I use any narcotics."

7 / 10
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34 Report

Frequently asked questions

  • Anonymous
  • May 11, 2009

For Pain "I am a long-term Ultram user (maybe 5 or 6 years). I have osteoarthritis. Now I feel like I am taking the medicine just to get rid of the headache and runny nose that I get when I do NOT take it. I am trying to STOP taking it and maybe switch to arthritis strength Tylenol. At least I won't have a headache and a runny nose. I think it addressed my pain very well some years ago, but now it's not working because I still have arthritis pain."

5 / 10
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37 Report
  • sto...
  • March 27, 2008

For Pain "I am now on my first refill of tramadol and recognize it does decrease the pain level. The prescription is written for two pills per day, but I have done that only twice. Each time getting a headache, so I continue to take it only at night just before bedtime. My next trip to the doctor, I will ask if it has anything to do with the stomach pain which I have begun to experience and originally thought the pain had to do with consuming wheat (bread), but eliminated all wheat from my diet."

7 / 10
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35 Report

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  • all...
  • July 26, 2009

For Pain "A doctor gave me Ultram with Trazodone for a sprained wrist and insomnia/anxiety. I took them both at bedtime, and by morning, I was throwing up with one of the worst headaches of my life, on my birthday. I threw up all day."

1 / 10
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23 Report
  • Anonymous
  • December 25, 2010

For Pain "I was prescribed tramadol for a severe sore throat. I couldn't eat anything or take my other medicines before taking it and was only able to drink enough to keep me hydrated. Although I have experienced headaches and nausea since taking it, I can at least eat soft foods and soup and take my other medications. The headaches and nausea aren't pleasant, but, after losing 6 lbs in 2 days because I couldn't eat, the benefits definitely outweighed the side effects."

8 / 10
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17 Report

More FAQ

  • Anonymous
  • Taken for less than 1 month
  • November 21, 2020

For Pain "I was given Ultram after an eye surgery that repaired a blown-out eye socket. Originally given Tylenol #3 but found I reacted to it with a rash and severe itching. I only used two doses of the Ultram and experienced worse headache than not taking it. It's useless for post-op pain. Doctors nowadays are careful (as they should be) when prescribing opiates, however, not all patients are seeking a high. It's frustrating to be put into a fishbowl with drug users. If a patient is seeking any kind of medication for a 'high,' then any class of opiates should not be prescribed. The possible side effects of Ultram, in my opinion, are scary, just as the side effects of Norco and such. That's why you listen to your body and watch for any side effects. For those who are increasing the dose, it is stupid as well as dangerous. But if taken as directed, although like me after 2 doses I knew it was pointless, there shouldn't be any real problems."

1 / 10
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7 Report
  • Anonymous
  • July 12, 2009

For Pain "I have used Ultram at night along with Xanax. It does allow me more sleep than before, usually around 4 hours. I do notice a headache, especially if I take a second dose later at night. I will wake with a headache. I've been taking it for about a year but do not notice any withdrawal if I miss any doses."

6 / 10
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11 Report
  • Anonymous
  • April 11, 2010

For Pain "Little, if any, pain relief. Stomach aches, headaches, and lethargic."

1 / 10
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14 Report
  • Dak...
  • Taken for 1 to 2 years
  • October 6, 2021

For Back Pain "Ultram is totally different from the generic tramadol. Much, much better. I had to switch as it was giving me headaches. I take more than 2x the tramadol than what I take of Ultram."

10 / 10
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2 Report
  • Anonymous
  • October 23, 2009

For Pain "I hurt my knee and was given this for pain. Gives me a headache and doesn't really curb the pain."

5 / 10
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7 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.