Zepbound User Reviews & Ratings (Page 4)

• hel...
• Taken for 6 months to 1 year
• November 20, 2024

For Weight Loss (Obesity/Overweight) "I started taking this in March 2024. I've had some weight loss (about 30 pounds), but not as much as I anticipated. I occasionally experience nausea and stomach pain, but it's usually after a very fatty meal (avoiding those types of foods minimizes this symptom for me). When I reached the 10 ml dose, I began having an itchy, raised red area surrounding the injection site that dissipates by the end of the week. I had one shot that didn't dispense the needle until I held it up to inspect it. I am happy I started this medication because I did lose weight (and hopefully will continue to) and was able to stop taking metformin! The worst thing about taking this medication is trying to get the prescription filled. I have had more issues trying to get my refills for Zepbound than any prescriptions for opioid pain medication (which I have taken in the past post-surgery due to an allergy to acetaminophen). At first, it was supply issues. Now it's preauths and difficulty staying at a certain dose."

• Jen...
• Taken for 1 to 6 months
• May 18, 2025

For Weight Loss (Obesity/Overweight) "I just started Zepbound in March, and I’m on the 2.5. Let me tell you, it’s a miracle drug. I was 190, and I’m down to 181 in three weeks. I’m losing it slow, and that’s how I’m doing it. The nausea sucked, but I got Zofran for it. I include exercise and water and eating a balanced diet. I use monk fruit for sugar because I’m a huge sugar girl. It’s been an amazing journey so far. I plan to stay on 2.5 because I don’t want to lose it too fast. I don’t have far to go! Target weight 170!"

• Dee...
• Taken for 1 to 6 months
• November 4, 2024

For Weight Loss (Obesity/Overweight) "Started on Zepbound 8/16/24. Have concentrated on protein and vegetables, fruit, and occasional treat. Have lost 31 lbs as of 11/2/24. Side effects have been constipation, which was remedied with OTC collagen and senna. Occasional nausea, especially in the beginning of tx. No longer get hungry and, most importantly, no longer get the cravings for unhealthy food. Recently started walking as it is much easier now with 30+ pounds down. Signed up for 2 exercise classes: yoga and weights. Dilkind has been a game changer for me. Presently on 2.5 injections. Easy to use."

• 215...
• Taken for 1 to 6 months
• November 11, 2024

For Weight Loss (Obesity/Overweight) "First things first. I'm a 40-year-old woman. My height is 5'9", and my starting weight was 214. During my first month on Zepbound 2.5 mg, I experienced fatigue, dry mouth, and slight constipation. I'm on my second month dosage of 5 mg now, and I'm experiencing nausea and migraines. This is my sixth injection, and the weight fell off during the first month, and now I'm at a standstill. I'm weighing in at 195 for the last 2 weeks. During my first month, I had no carbs at all. I made sure I had at least 120 g of protein a day, and I weight trained four times a week, getting my goal of 10,000 steps a day. I haven't kept that same training routine these past two weeks, which is why I probably haven't lost any weight. I'd say the medicine really works. I'm not looking to stay on long-term. Since I hit 40, I've struggled with weight, perimenopause, etc. This has been a game changer."

• Ano...
• Taken for 1 to 6 months
• May 4, 2025

For Weight Loss (Obesity/Overweight) "Zepbound has been wonderful. Started at 2.5, now starting 7.5. Working. Side effects: some nausea, constipation, but not bad. Injection site reaction, but within 3 or 4 days, fading away. Really an easy medication to tolerate. Glad I am on Zepbound."

• Mec...
• Taken for 1 to 6 months
• July 28, 2024

For Weight Loss (Obesity/Overweight) "Made my anxiety more intense, bad nausea, lightheaded, dizzy, not feeling like myself, not interested in anything, depressed. The only good thing was I was losing weight, very slowly but was losing. I decided to stop Zepbound because I needed to feel like me again and not a nervous, anxious zombie."

• Mk6...
• Taken for 1 to 6 months
• March 10, 2025

For Weight Loss (Obesity/Overweight) "I started in January 2025 with the 2.5 dose. For the first two weeks, I experienced nausea and diarrhea off and on. For the last two weeks, I was fine. I am on my second week of 5 mg. The first week, I was so sick - I take the shot late Friday afternoon - I was in bed most of the day on Saturday with nausea and fatigue. I did vomit once. Sunday was the same. The rest of the week, I felt fine. Second shot last Friday - I was okay on Saturday - able to function but very nauseous. Woke up on Sunday and spent most of the day in bed due to nausea and fatigue. The anti-nausea medicine helps but not so much for me. Today I am functioning with some nausea. The benefits of this drug are obvious. I don't eat as much as I did before the medicine. I've lost 16 lbs so far. The nausea bothers me. I should be able to function and not get sick every weekend after a shot. I no longer have diarrhea - I am constipated instead. When I take Miralax, I cannot think about it or I get sick."

• jme...
• Taken for 1 to 6 months
• March 13, 2025

For Weight Loss (Obesity/Overweight) "There are pros and cons to every medication that you take. Zepbound does help with weight loss. Your appetite decreases, but you can and will have GI side effects: constipation, gas, abdominal pain with overeating, belching, and nausea. Cutting back on carbonated beverages, eating small meals, and increasing protein and fiber is key. Adding nausea medication and Gas-X helps."

• Hai...
• Taken for 1 to 6 months
• December 6, 2024

For Weight Loss (Obesity/Overweight) "The first couple of weeks, I was nauseous throughout the day. I had a hard time eating more than a couple of bites and didn't want to drink anything. Then I made myself eat a very light breakfast, protein drinks for lunch, a small portion of food for supper. Drinking a bottle of water with each meal and an extra one in the evening. Now on my 11th weekend, all's well. Oh, and I had to give up caffeinated coffee, it was contributing to my nausea in the first two weeks. Started at 239 lbs, 5'9'', 69 yrs. old. Now at 210.4 lbs."

• Use...
• Taken for 6 months to 1 year
• March 5, 2025

For Weight Loss (Obesity/Overweight) "I have been using weekly Zepbound shots since July 23rd, 2025…6-7 months. I have lost 47 lbs., which is 23% of my body weight. I have had occasional waves of nausea, but not so bad that it made me want to quit. My sleep has been disrupted some nights when I can’t go back to sleep after waking up. I’m currently up to 7.5 mg. And I’ve started taking the shots every 10 days instead of 7 days so I can gradually wean myself off of it. I have about 5 lbs. to go to meet my personal goal and about 10 lbs. to be off of the “overweight” BMI chart. I have been seeing my doctor every 3 months for bloodwork and check-ups. I am happy that I decided to try Z, and I’m also pleased that my insurance company paid for all of it except for $25 a month. Totally worth it."

• JoD...
• Taken for less than 1 month
• September 7, 2025

For Weight Loss (Obesity/Overweight) "I started Zepbound with the expected side effects, chills, extreme fatigue, nausea, massive potty dumps. I am now down with days of horrible abdominal intestinal pain. I cannot go to the bathroom! I have stopped this med."

• Lis...
• Taken for 1 to 6 months
• September 8, 2025

For Weight Loss (Obesity/Overweight) "I am 58 years old and in menopause, and I have been on Zepbound for about 3 months now. I know that a lot of people say that they have had a lot of side effects. My experience has been great! I am still on the lowest dosage and have lost 24 lbs. I have been on cloud 9 because I am losing the weight, and with no side effects at all. I only had a very light tummy ache 2 times along with nausea the first week, but it was not bad at all. It was very, very slight and only lasted about 5 minutes each time. Since then, I have not had any side effects at all. I would say yes, that I do recommend Zepbound, but it is not for everyone. You can at least try it and give it about 2 weeks and see how it works for you. I say 2 weeks because it was my second week that I had absolutely no side effects. I honestly don't even want to admit the minor side effects that I had the first week because it was so minor. You never know, you might like it and love it! I would at least give it a try."

• Tri...
• Taken for 1 to 6 months
• September 3, 2025

For Weight Loss (Obesity/Overweight) "I have been on Zepbound for a month now, lowest dosage of 2.5 mg, and today I'm to start my second month with the next dosage up, but personally, I'm done. I've lost 7 pounds this August 2025, and though it may not seem like a lot to most people, it's quite something to those of us who have a very hard time losing weight. The thing is, how can a person be happy with the weight loss when you're miserable all the time? My first week went well, but come the second, the stomach aches/cramps and nausea are too much... every day, all day, through the night... sicker than a dog. I've heard good things about Zepbound, but the side effects are just too much for anyone to feel good about the journey it takes you on, and if the side effects only get worse with the higher dosages, then I might as well not eat at all for what little I can now, when I can. I'm 300+ pounds, and this was my last hope for any type of weight loss help. I don't recommend this product, the side effects outweigh any of the happy."

• Ano...
• Taken for 1 to 6 months
• June 22, 2025

For Weight Loss (Obesity/Overweight) "I started taking Zepbound five weeks ago. I started with 2.5. My first couple of weeks were fine, but by my third week after that shot, I could not eat for 3 days. I tried even sipping on water and couldn't because of the nausea. My throat kind of burnt all the way down to my stomach, it felt like someone was squeezing the top of my throat. I just took my first shot of the 5.0 3 days ago, and I still haven't been able to eat because I'm so nauseous, and again my stomach's hurting. I tried yesterday to take some Rolaids, but that made me throw up. I haven't told my doctor, and I'm still going to continue taking it, but if this keeps up, it's not worth it. But I will continue to try maybe one or two more weeks, but if it just keeps up and is this miserable, I'm going to stop taking it. Hopefully, no one else has this feeling. But I didn't lose 19 lb in one month. I hope everyone does better on it than I am."

• Sus...
• Taken for 1 to 6 months
• April 7, 2024

For Weight Loss (Obesity/Overweight) "Nausea and constipation. I started on 2/22/2024 at 207 pounds, and now on 4/7/2024, I weigh 180 pounds."

• Suz...
• Taken for 1 to 6 months
• January 23, 2025

For Weight Loss (Obesity/Overweight) "Encounter burping, nausea, and can’t fall asleep easily."

• Mys...
• Taken for 1 to 6 months
• August 13, 2025

For Weight Loss (Obesity/Overweight) "I am the third 5 mg injection. There have been some nausea, much more than while on 2.5 mg, some vomiting, and a mild sore throat. My weight loss is pretty consistent at 1.5 lbs a week."

• Ano...
• Taken for less than 1 month
• May 14, 2025

For Weight Loss (Obesity/Overweight) "I have lost 14 lbs in 4 weeks. Extreme fatigue and a little nausea. A little shortness of breath when walking. Feeling weak."

• Den...
• Taken for less than 1 month
• July 14, 2024

For Weight Loss (Obesity/Overweight) "Works for weight loss if you can tolerate it. I went to the ER with nausea, vomiting, severe depression, and anxiety. Won't be continuing."

• Cry...
• Taken for 6 months to 1 year
• February 21, 2025

For Weight Loss (Obesity/Overweight) "I've lost 67 lbs in 10 months. Only side effects have been some constipation and slight nausea. This has been a life changer for sure!"

• Mor...
• Taken for less than 1 month
• July 21, 2025

For Weight Loss (Obesity/Overweight) "So far, so good. I am suffering from the nauseated feeling, burping, fatigue, and muscle cramps. I'm at 2.5 level, week 3. I'm definitely eating a lot less."

• Ano...
• Taken for less than 1 month
• May 27, 2025

For Weight Loss (Obesity/Overweight) "Just got started, currently in my 3rd week. Moderate to severe diarrhea started after the 3rd shot. No nausea at this point. Some stomach pain."

• Vio...
• Taken for 1 to 6 months
• November 24, 2024

For Weight Loss (Obesity/Overweight) "For the most part, my biggest side effect has been burping and nausea. Even before using this medication, I had bouts of reflux."

• Suz...
• Taken for 6 months to 1 year
• April 14, 2025

For Weight Loss (Obesity/Overweight) "Having great success with weight loss but having trouble with nausea and vomiting."

• San...
• Taken for 1 to 6 months
• July 2, 2024

For Weight Loss (Obesity/Overweight) "Had just a little nausea. Love the ease of the shot. Weight loss is great."