Zepbound User Reviews & Ratings (Page 3)

• agm...
• Taken for 1 to 6 months
• December 18, 2024

For Weight Loss (Obesity/Overweight) "I have been on Zepbound for 16 weeks. I have lost 23 lb. I am a 6'3" 74-year-old man. I wanted a kick start to get to my goal, which I am at. Except for three weeks at 5 mg, I have been on 2.5 and am now after a brief go at 5 mg. My experience has been generally acceptable, but nausea and fatigue are a real challenge. No vomiting or diarrhea. I have had some acid reflux. The key has been to eat good clean food and stay away from fried or greasy. I have reduced my alcohol intake, but they are empty calories, and why do it? It just makes it tougher. The reason I drink some is usually social, but I have found it easier to abstain than I expected. Here's the deal: I think people lose weight on these drugs because they don't want to get sick and choose to behave and stay at a calorie deficit, and bingo, the math kicks in. It's not rocket science. I have taken a week off while on an overseas trip. Again, I didn't want to get sick. I am about to take another week off."

• Pau...
• April 23, 2024

For Weight Loss (Obesity/Overweight) "I am a 72-year-old female, 5'7", and 204 lbs. I started Zepbound 3 weeks ago. I don't have the nausea, diarrhea, and other ailments that I've read about, but I've had a problem with itching. From the top of my thighs, up my back and my front and my arms all itch a lot. My doctor told me to quit the injections for 3 weeks to see if it helped. For the first time, I didn't do what he recommended because at this point, I've lost 7 lbs and I'm very happy about that. Hopefully the itching will die down with time. I'm very optimistic about my success and I will continue. It's only costing me $245 a month which is very doable. Taking Benadryl and using cortisone cream seems to help."

• 123...
• Taken for 1 to 6 months
• September 16, 2024

For Weight Loss (Obesity/Overweight) "I began this treatment in April. It is now mid-September. I have lost 20 pounds. It is very easy to use, which is a big deal for those who have a needle phobia. In the beginning, I had very few side effects. After going to the 7.5 mg dose, I started to experience constipation and nausea. To combat this, I began a small fiber intake routine and requested Zofran from my doctor. Both are very effective for those side effects. I am now on a 12.5 mg dose and doing well. I feel I am close to a maintenance dose. This medication was quite effective. I am a small person, menopausal, and struggled with losing weight. Losing 20 lbs for my size is a very big deal. Through this process, I have learned better eating habits, keeping my portions small to maintain a healthy weight and continuing my exercise routine even if I am not losing weight. All in all, this was a win-win for me."

• San...
• Taken for 1 to 6 months
• May 2, 2024

For Weight Loss (Obesity/Overweight) "I am African American, age 54, weight 225 lbs. I started Zepbound a month ago after previously trying to lose weight with Wegovy in 2023 but ran into demand issues with Wegovy. Wegovy also gave me extreme nausea and vomiting but amazing weight loss results. Zepbound's needles leave bruises, and I get tension headaches on the 1st and 2nd day after injection. I also feel tired on the 2nd and 3rd day, but I am not as hungry. I do notice that when I eat poorly, I have explosive BMs, and when I eat clean, I feel constipated. I do notice the weight loss on the 2.5 mg dose but can't move into 5.0 due to shortages, and I am hoping it's not like my experience with Wegovy, and I'll have to stop the progress due to the shortage of dosages."

• dfx...
• Taken for less than 1 month
• January 12, 2025

For Weight Loss (Obesity/Overweight) "I started May 2024 with a compounded GLP-1, which worked great (some nausea), 186lbs down to 147lbs. However, I stopped working, so I switched to trizepitide 2.5 this week. Absolutely no side effects. I've already lost a pound. Once I get below 140, I'm going to go to only 2 shots a month for maintenance. I'm doing this through a clinic. I can't say enough how great I feel. I've done every diet in the book. It's the best gift you'll give yourself ever. I pay $300 for 4 shots."

• jme...
• Taken for 1 to 6 months
• March 13, 2025

For Weight Loss (Obesity/Overweight) "There are pros and cons to every medication that you take. Zepbound does help with weight loss. Your appetite decreases, but you can and will have GI side effects: constipation, gas, abdominal pain with overeating, belching, and nausea. Cutting back on carbonated beverages, eating small meals, and increasing protein and fiber is key. Adding nausea medication and Gas-X helps."

• Whi...
• Taken for 1 to 6 months
• August 17, 2024

For Weight Loss (Obesity/Overweight) "I have been taking this medication now approaching the 6-month marker, and it has been wonderful for weight loss in my experience so far! I did my starter 2.5 mg dose for the first month and then went to the 5 mg and stayed there for 4 months before deciding to go up to the 7.5 mg, which is what I am currently on. I have definitely experienced some of the side effects, but they are pretty mild and typically only happen the day after taking my weekly shot, and then it gets better except for 1. I am always very nauseous the day after the shot when changing doses, but once I've been on a dose for a couple weeks, the nausea lessens quite a bit. But something that just randomly started happening about halfway into all of this, I started having major skin irritation with the injection spot, which freaked me out only because I had been taking it for months before it started happening just out of nowhere, and it wasn't when I changed a dose or done anything differently, and it's continued to happen every time!"

• Anonymous
• Taken for 6 months to 1 year
• March 4, 2025

For Weight Loss (Obesity/Overweight) "It was rough in the beginning, with diarrhea, then constipation and heavy belching. The diarrhea ended after about a month, but constipation has continued. In addition to those symptoms, I experienced an undercurrent of nausea for several months, with it being more pronounced just after eating. After about eight months, the nausea abated for the most part. I started on the 2.5 and moved up in dosage every 2 months or so. I am entering month 10 and am on the 12.5 dosage. For the first 6-7 months, I lost approximately 1.5 lbs/wk, and over the last 2-3 months that has slowed down a little. I have lost a total of 50 lbs. The other side effect I've experienced is I sometimes have low blood sugar in the mornings, so I will have juice or something to help take care of it. It is easy to use, and despite the rough start, I am pleased with the results."

• hel...
• Taken for 6 months to 1 year
• November 20, 2024

For Weight Loss (Obesity/Overweight) "I started taking this in March 2024. I've had some weight loss (about 30 pounds), but not as much as I anticipated. I occasionally experience nausea and stomach pain, but it's usually after a very fatty meal (avoiding those types of foods minimizes this symptom for me). When I reached the 10 ml dose, I began having an itchy, raised red area surrounding the injection site that dissipates by the end of the week. I had one shot that didn't dispense the needle until I held it up to inspect it. I am happy I started this medication because I did lose weight (and hopefully will continue to) and was able to stop taking metformin! The worst thing about taking this medication is trying to get the prescription filled. I have had more issues trying to get my refills for Zepbound than any prescriptions for opioid pain medication (which I have taken in the past post-surgery due to an allergy to acetaminophen). At first, it was supply issues. Now it's preauths and difficulty staying at a certain dose."

• Pro...
• Taken for 6 months to 1 year
• February 25, 2025

For Weight Loss (Obesity/Overweight) "I’ve been on Zepbound since 8/1/24 (305 lbs, 5’6). So far, I lost 65 lbs, I’m 45 lbs away from my goal. My current dose is 10 mg. I experience side effects within 24 hours of injection administration, ranging from nausea, vomiting, belching, diarrhea, abdominal pain, fatigue, and dizziness. The side effects last about 24-36 hours. The medication definitely decreases my appetite and cravings. My doctor stopped my BP medication as I continue losing weight and my BP readings are good. My husband has noticed that I stopped snoring, lol. My plan is to reach my weight goal and stop the medication. I have changed my relationship with food. I look at food more as fuel for my body instead of indulging and overeating. I also introduced portion control and exercise, mostly walking and swimming. My insurance covers the medication."

• Suz...
• Taken for 6 months to 1 year
• February 26, 2025

For Weight Loss (Obesity/Overweight) "I began my weight loss journey in late January 2024. Over the next 12 months, I lost 40 pounds. However, I've hit a plateau for the past four months, since the end of November 2024, and it's now February 25, 2025. I still need to lose at least another 40 pounds. Zepbound has been a significant help in my journey. My clothes fit much better, and I've gone from a size XXL to a medium. In addition to Zepbound, I also strength train, maintain a healthy diet, and track my calorie intake. The only side effects I've experienced with Zepbound are occasional acid reflux, mild nausea, and some constipation. Currently, I am on 12.5 mg, but my doctor has decided to update my dosage to the 15 mg to see how I do on that dosage. Hopefully, it will kick me over the plateau and I will end up losing the next 40 pounds that I need to. Other than that, I love Zepbound. I think it’s great."

• Dee...
• Taken for 1 to 6 months
• November 4, 2024

For Weight Loss (Obesity/Overweight) "Started on Zepbound 8/16/24. Have concentrated on protein and vegetables, fruit, and occasional treat. Have lost 31 lbs as of 11/2/24. Side effects have been constipation, which was remedied with OTC collagen and senna. Occasional nausea, especially in the beginning of tx. No longer get hungry and, most importantly, no longer get the cravings for unhealthy food. Recently started walking as it is much easier now with 30+ pounds down. Signed up for 2 exercise classes: yoga and weights. Dilkind has been a game changer for me. Presently on 2.5 injections. Easy to use."

• Mec...
• Taken for 1 to 6 months
• July 28, 2024

For Weight Loss (Obesity/Overweight) "Made my anxiety more intense, bad nausea, lightheaded, dizzy, not feeling like myself, not interested in anything, depressed. The only good thing was I was losing weight, very slowly but was losing. I decided to stop Zepbound because I needed to feel like me again and not a nervous, anxious zombie."

• Hai...
• Taken for 1 to 6 months
• December 6, 2024

For Weight Loss (Obesity/Overweight) "The first couple of weeks, I was nauseous throughout the day. I had a hard time eating more than a couple of bites and didn't want to drink anything. Then I made myself eat a very light breakfast, protein drinks for lunch, a small portion of food for supper. Drinking a bottle of water with each meal and an extra one in the evening. Now on my 11th weekend, all's well. Oh, and I had to give up caffeinated coffee, it was contributing to my nausea in the first two weeks. Started at 239 lbs, 5'9'', 69 yrs. old. Now at 210.4 lbs."

• 215...
• Taken for 1 to 6 months
• November 11, 2024

For Weight Loss (Obesity/Overweight) "First things first. I'm a 40-year-old woman. My height is 5'9", and my starting weight was 214. During my first month on Zepbound 2.5 mg, I experienced fatigue, dry mouth, and slight constipation. I'm on my second month dosage of 5 mg now, and I'm experiencing nausea and migraines. This is my sixth injection, and the weight fell off during the first month, and now I'm at a standstill. I'm weighing in at 195 for the last 2 weeks. During my first month, I had no carbs at all. I made sure I had at least 120 g of protein a day, and I weight trained four times a week, getting my goal of 10,000 steps a day. I haven't kept that same training routine these past two weeks, which is why I probably haven't lost any weight. I'd say the medicine really works. I'm not looking to stay on long-term. Since I hit 40, I've struggled with weight, perimenopause, etc. This has been a game changer."

• Use...
• Taken for 6 months to 1 year
• March 5, 2025

For Weight Loss (Obesity/Overweight) "I have been using weekly Zepbound shots since July 23rd, 2025…6-7 months. I have lost 47 lbs., which is 23% of my body weight. I have had occasional waves of nausea, but not so bad that it made me want to quit. My sleep has been disrupted some nights when I can’t go back to sleep after waking up. I’m currently up to 7.5 mg. And I’ve started taking the shots every 10 days instead of 7 days so I can gradually wean myself off of it. I have about 5 lbs. to go to meet my personal goal and about 10 lbs. to be off of the “overweight” BMI chart. I have been seeing my doctor every 3 months for bloodwork and check-ups. I am happy that I decided to try Z, and I’m also pleased that my insurance company paid for all of it except for $25 a month. Totally worth it."

• Mk6...
• Taken for 1 to 6 months
• March 10, 2025

For Weight Loss (Obesity/Overweight) "I started in January 2025 with the 2.5 dose. For the first two weeks, I experienced nausea and diarrhea off and on. For the last two weeks, I was fine. I am on my second week of 5 mg. The first week, I was so sick - I take the shot late Friday afternoon - I was in bed most of the day on Saturday with nausea and fatigue. I did vomit once. Sunday was the same. The rest of the week, I felt fine. Second shot last Friday - I was okay on Saturday - able to function but very nauseous. Woke up on Sunday and spent most of the day in bed due to nausea and fatigue. The anti-nausea medicine helps but not so much for me. Today I am functioning with some nausea. The benefits of this drug are obvious. I don't eat as much as I did before the medicine. I've lost 16 lbs so far. The nausea bothers me. I should be able to function and not get sick every weekend after a shot. I no longer have diarrhea - I am constipated instead. When I take Miralax, I cannot think about it or I get sick."

• Sus...
• Taken for 1 to 6 months
• April 7, 2024

For Weight Loss (Obesity/Overweight) "Nausea and constipation. I started on 2/22/2024 at 207 pounds, and now on 4/7/2024, I weigh 180 pounds."

• Suz...
• Taken for 1 to 6 months
• January 23, 2025

For Weight Loss (Obesity/Overweight) "Encounter burping, nausea, and can’t fall asleep easily."

• Cry...
• Taken for 6 months to 1 year
• February 21, 2025

For Weight Loss (Obesity/Overweight) "I've lost 67 lbs in 10 months. Only side effects have been some constipation and slight nausea. This has been a life changer for sure!"

• Vio...
• Taken for 1 to 6 months
• November 24, 2024

For Weight Loss (Obesity/Overweight) "For the most part, my biggest side effect has been burping and nausea. Even before using this medication, I had bouts of reflux."

• Den...
• Taken for less than 1 month
• July 14, 2024

For Weight Loss (Obesity/Overweight) "Works for weight loss if you can tolerate it. I went to the ER with nausea, vomiting, severe depression, and anxiety. Won't be continuing."

• Suz...
• Taken for 6 months to 1 year
• April 14, 2025

For Weight Loss (Obesity/Overweight) "Having great success with weight loss but having trouble with nausea and vomiting."

• San...
• Taken for 1 to 6 months
• July 2, 2024

For Weight Loss (Obesity/Overweight) "Had just a little nausea. Love the ease of the shot. Weight loss is great."