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Tirzepatide and Vomiting: What Users Say (Page 4)

Brand names: Mounjaro, Zepbound

Reviews for Tirzepatide

Commonly mentioned side effects
  • Me1...
  • Taken for 1 to 6 months
  • March 7, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "I started off with 2.5 mg the first month. Second month is 5 mg. Today I take the 3rd needle from the package. Last night was the first time I was nauseous and vomiting. I don't know if it was from the medication, but that day I had eaten chips and chocolate. I had not since I started. I want to believe eating those led me to being sick. Burping started about 3 weeks ago but only lasts for a day. It has happened 3 times. Been stuck on the same weight for 2 weeks."

7 / 10
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  • SLB...
  • Taken for less than 1 month
  • March 13, 2023

Tirzepatide for Type 2 Diabetes "Had my first dose yesterday, 3/12/23, and today I have intense nausea, and it feels like a rock in my gut. I also have a prescription for an anti-nausea med, which I am not sure is working since I feel like throwing up. It did lower my BGM pretty well. I had previously tried Ozempic with horrible side effects of nausea and vomiting. I lasted the first week, so one dose. I do like the way Mounjaro is administered. I don't think the Ozempic was quite like that."

5 / 10
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  • No1...
  • Taken for 1 to 6 months
  • June 15, 2025

For Weight Loss (Obesity/Overweight) "Zepbound is working for me. I'm down 12 lbs. This is my first month of use. There has been no pain or bruising from the injections. I have to be mindful to eat a small portion. No sugar, I did fine using a little Stevia once. I have slept well. I have energy for pool and Silver Sneakers classes. Some walking. The reprisals are swift and brutal. Later on in the wee hours, I had miserable cramping and diarrhea. Have a receptacle ready because there will be violent vomiting. Vomiting subsides sooner than low abdominal cramping with diarrhea 3 to 5 hours of every few minutes back to the bathroom after being on the toilet for 10 to 20 minutes at a time. Chew your food, don’t eat fast. I do feel full all the time. I will be hungry but for just a little. My stomach is fine otherwise. When the punishment in the restroom is over, it's like it never happened. I’ve noticed I have a strong odor I didn’t have before. Breath, gas, body odor, number 2. It’s manageable."

10 / 10
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Frequently asked questions

  • Ano...
  • Taken for 1 to 2 years
  • May 20, 2025

For Weight Loss (Obesity/Overweight) "When I first started on the 2.5 dose, I had some mild side effects, which included nausea and one episode of vomiting. I slowly increased to 12.5 mg over 3 or 4 months. I had to re-learn what it felt like to actually be full. Zepbound helped me lose 80 pounds in a little over a year and keep it off, but I think the combination of the medication and health coaching helped me to be aware and notice what was happening in my body, which is what is helping me keep the weight off. People say medication is the easy route for weight loss, but that's not true. The medication helped, but I still had to put the work in for myself."

10 / 10
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  • Jax...
  • Taken for 1 to 6 months
  • June 5, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "The only time I've experienced vomiting was after eating greasy food then drinking wine, otherwise, none. I've had a little nausea, but nothing to concern me. I'm steadily losing weight, and in 11 weeks, I'm down 19 lbs with about 10 more to go until I'm at a healthier weight for my height. A couple of people have criticized me for using it, but I was using a calorie deficit and intermittent fasting while exercising every day, but just not losing anything, so I'm happy with my decision to start taking it."

10 / 10
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  • Rut...
  • Taken for 2 to 5 years
  • May 31, 2025

Tirzepatide for Type 2 Diabetes "I’ve been taking Mounjaro for three years. Side effects in the beginning were pretty bad. I had stomach issues that took time and trials to get under control. I also was uncomfortably cold. The stigma of losing weight was a new thing for me. Family thought I had an eating disorder. I vomited a lot in the first year. I lost 70 pounds. I lost a ton of hair and muscle. Today, I am on a maintenance dose of 10. I have put back on 15 pounds, and I’m good with that. My A1C is stable at 5.7. I still crave healthy foods instead of junk. My aversion to fried food and meats is still active. I take 2 stool softeners and 1 tablespoon of MiraLAX daily. Drink plenty of fluids to keep things flowing. I would do it all over even knowing the struggles. The benefits are too much to list."

10 / 10
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  • BBr...
  • Taken for 1 to 6 months
  • May 1, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "I have had to stop. Cannot eat, close to vomiting, have lost 30 pounds. Dr. advised to stop, but I had already stopped 2 weeks ago as unable to eat. I was afraid to start the next box I had received. I am so weak I can barely walk. I do use a rollator to help me walk, but in the house I can hold onto furniture to help my balance."

5 / 10
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More FAQ

  • Ano...
  • Taken for 1 to 6 months
  • April 26, 2025

For Weight Loss (Obesity/Overweight) "Was doing great at 2.5 for 3 weeks, then went up to 5.0 mg for 2 weeks. Made a huge mistake of going up again to 7.5. At this doing, I had lost 6 lbs and thought it was slow results. I was vomiting nonstop for a day and a half. Could not even keep water down. I called my doctor for nausea pills. The third day I was feeling somewhat better, but still burping. I would recommend staying on the lower doses based on my experience. I have lost a total of 11 lbs after emptying my stomach. Be patient."

6 / 10
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  • Flo...
  • Taken for less than 1 month
  • December 22, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "This medicine has made me so sick. I will never take it again. I have not eaten in over five days. I am so weak, I feel like my blood sugar is low. I am not a diabetic, I only wanted to lose a few pounds. I have been sick, nauseous, vomiting, fatigue, diarrhea. Until I got everything out of my belly, my belly felt full, even when I did not eat. Constant belching. My food does not taste good. I am miserable. I’m sure it has great benefits. My other family members took it, as for me, whom is diabetic, extremely curvy, but just wanted to lose excess belly fat. I probably should’ve just gone to the gym, exercised more, or even worn a waist trainer. To me, in my opinion, it’s not worth it."

5 / 10
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  • Den...
  • Taken for less than 1 month
  • July 14, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "Works for weight loss if you can tolerate it. I went to the ER with nausea, vomiting, severe depression, and anxiety. Won't be continuing."

6 / 10
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  • Mys...
  • Taken for 1 to 6 months
  • August 13, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "I am the third 5 mg injection. There have been some nausea, much more than while on 2.5 mg, some vomiting, and a mild sore throat. My weight loss is pretty consistent at 1.5 lbs a week."

9 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • February 14, 2023

Tirzepatide for Type 2 Diabetes "Vomiting and rash, with severe itching. No weight loss."

1 / 10
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  • Kat...
  • Taken for 1 to 6 months
  • June 22, 2023

Tirzepatide for Weight Loss (Obesity/Overweight) "25 lbs in 60 days weight loss. Side effects minimal include vomiting and constipation. 2.4 mg for 30 days, 5 mg for 30 days. SW 175. CW 146. Height 5'0", age 41, female."

8 / 10
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  • Jew...
  • Taken for less than 1 month
  • May 30, 2023

Tirzepatide for Weight Loss (Obesity/Overweight) "It was fine for two days, but then after that, it was awful. I had vomiting, gas so bad I hurt, and weakness, and lost 10 pounds in three days. The doctor said not to take it again."

4 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • February 10, 2025

Tirzepatide for Type 2 Diabetes "Nausea and vomiting the day of and day after injection."

8 / 10
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  • pla...
  • Taken for less than 1 month
  • June 6, 2023

Tirzepatide for Type 2 Diabetes "My doctor had me stop the drug after 4 weeks of projectile vomiting, acid indigestion, heartburn, and acid reflux. I was sad that it didn't work with my body as I lost 15 lbs in 4 weeks."

2 / 10
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  • dow...
  • Taken for 1 to 2 years
  • July 15, 2024

Tirzepatide for Type 2 Diabetes "Every once in a while, I get an acidic stomach and then vomit. This has only happened three times in a year."

9 / 10
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  • Hon...
  • Taken for 1 to 6 months
  • April 6, 2023

Tirzepatide for Type 2 Diabetes "It has made me have projectile vomiting and headaches every day. The doctor said to stay with it, but I don't think I can."

3 / 10
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  • K B...
  • Taken for less than 1 month
  • March 14, 2025

Tirzepatide for Type 2 Diabetes "It does what it says, but it causes major nausea and vomiting."

6 / 10
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  • Del...
  • Taken for 1 to 6 months
  • March 19, 2025

Tirzepatide for Type 2 Diabetes "Did fine until larger dose 7.5, and after a few days, would throw up everything in my stomach. Have lost several pounds due to regulation. Otherwise, so far, so good. My A1c has dropped to 7."

8 / 10
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  • Ben...
  • Taken for 1 to 6 months
  • December 12, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "Hyper skin sensitivity. Sore throat, raised glands in neck, bad headaches, vomiting, acid reflux. Constipation. Lower back pain."

10 / 10
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  • Lin...
  • Taken for less than 1 month
  • May 13, 2025

Tirzepatide for Type 2 Diabetes "2.5 mg 3 weeks after the third dose, vomiting, diarrhea for 12 hours but continuing with diarrhea after any intake of food. Lost 10 lbs."

5 / 10
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  • Suz...
  • Taken for 6 months to 1 year
  • April 14, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "Having great success with weight loss but having trouble with nausea and vomiting."

8 / 10
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  • dav...
  • Taken for 6 months to 1 year
  • March 17, 2025

Tirzepatide for Type 2 Diabetes "Helps greatly with blood sugar control, but at a 10 mg dose, I am getting severe diarrhea and vomiting, usually the second day after the injection."

6 / 10
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  • Ano...
  • Taken for 1 to 2 years
  • May 21, 2025

Tirzepatide for Type 2 Diabetes "Effective, had some nausea/vomiting and stomach pain the first couple of months, but then resolved. Have lost over 40 pounds over 18 months and A1C is 5.3. Very satisfied."

9 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.