Tirzepatide and Stomach Pain: What Users Say (Page 3)

• pat...
• Taken for 1 to 6 months
• May 23, 2024

Tirzepatide for Type 2 Diabetes "I used this for the first month at 2.5mg and did fine. Didn't really notice too much change and minimal impact on my sugar numbers. After 1 month, my doctor increased the dosage to 10mg. From that point, day 1 after my shot, I experience complete loss of appetite, chills, gastric pain. Days 2-4, I just had the loss of appetite and gastric pain, soft stools. Day 5 after my shot, loss of appetite, pain & diarrhea. The 6th day, some appetite back, less pain, no BM at all. Day of next injection was good, was able to eat more, no pain, normal BM. Day after 2nd shot at 10mg, is repeating again. I was losing some weight at the lower dosage but the sugar numbers weren't that much improved. On the higher dosage, I'm no longer losing weight but my sugars are more in line and coming down."

• Jam...
• Taken for less than 1 month
• April 30, 2025

Tirzepatide for Type 2 Diabetes "I only took 3 doses at 2.5 mg. By the time I took the 2nd shot, I was having trouble with my stomach hurting and starting to itch. After the 3rd shot, I broke out with a rash on my back, arms, and stomach. I decided not to take the 4th shot and contacted my doctor. During my visit, they decided for me to come off of Mounjaro. I was given a steroid shot, oral medication, and an ointment for the rash. My stomach still bothers me some but seems to be getting better. This has been 4 weeks today, and the rash hasn’t gone away completely yet. When in direct sunlight, it seems to aggravate or excite the rash. I don’t know if Mounjaro has any effects on moodiness, but while I was taking it, I was in a really good mood. I would have moments of intense bliss. After I stopped using Mounjaro, I’ve had moments of moodiness. This is getting better, but I thought it’s worth mentioning."

• Jea...
• Taken for 6 months to 1 year
• May 6, 2025

Tirzepatide for Type 2 Diabetes "Have been on the 2.5 mg for almost a year. Do not want to increase dosage. Doctor is fine with that as well. I have lost about 70 lbs. since beginning this medication. My A1C is absolutely fantastic! Better than it has ever been. My weight is the lowest it's ever been. I was actually getting concerned with the weight loss and/or possible bad nutrition. However, my last labs were all fine! I've always concentrated on protein intake. I had gastric bypass back in 2006. Weighed 312 back then, am currently at 115. But do not look sickly or undernourished. I did have a recent ER visit for severe stomach pain. No other symptoms at all. They advised that I had ileus. So have several questions for the doctor at the follow-up visit this week. Have been type 2 for many, many years. Overall happy with the Mounjaro. Do have stomach pain at times, but it is manageable."

• Ano...
• Taken for 1 to 6 months
• June 22, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "I started taking Zepbound five weeks ago. I started with 2.5. My first couple of weeks were fine, but by my third week after that shot, I could not eat for 3 days. I tried even sipping on water and couldn't because of the nausea. My throat kind of burnt all the way down to my stomach, it felt like someone was squeezing the top of my throat. I just took my first shot of the 5.0 3 days ago, and I still haven't been able to eat because I'm so nauseous, and again my stomach's hurting. I tried yesterday to take some Rolaids, but that made me throw up. I haven't told my doctor, and I'm still going to continue taking it, but if this keeps up, it's not worth it. But I will continue to try maybe one or two more weeks, but if it just keeps up and is this miserable, I'm going to stop taking it. Hopefully, no one else has this feeling. But I didn't lose 19 lb in one month. I hope everyone does better on it than I am."

• Tip...
• Taken for 1 to 6 months
• December 8, 2024

Tirzepatide for Type 2 Diabetes "Try taking Benadryl 45 min before injection, and take/inject at night. I do this and don’t get the stomach pain or nausea."

• Ros...
• Taken for 1 to 6 months
• June 28, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "Raised red swollen area around injection site. Itchy stomach pain."

• Ano...
• Taken for less than 1 month
• May 27, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "Just got started, currently in my 3rd week. Moderate to severe diarrhea started after the 3rd shot. No nausea at this point. Some stomach pain."

• Ano...
• Taken for 1 to 6 months
• May 10, 2025

For Weight Loss (Obesity/Overweight) "Started slowly and now on 5 mg. Nausea and stomach pain, but tolerated."

• Orl...
• Taken for 1 to 6 months
• September 9, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "Lost 60 pounds in 4 months. Stomach pain and alternating diarrhea and constipation."

• Jea...
• Taken for 1 to 6 months
• April 9, 2023

Tirzepatide for Weight Loss (Obesity/Overweight) "I have had some mild stomach pain and mild constipation. I am not eating as much. I have some blurred vision, but not sure if it is related to the medication."

• Joh...
• December 12, 2024

Tirzepatide for Type 2 Diabetes "I am having severe stomach pain, and last week I had two swollen lymph nodes on my neck, but they have dissipated over the course of a week. I am on the highest dose of Mounjaro."

• Lin...
• Taken for 1 to 6 months
• November 24, 2024

Tirzepatide for Type 2 Diabetes "Better than Ozempic, which caused severe stomach pain even in low doses, and so far not the same side effects with Mounjaro."

• Rod...
• Taken for 1 to 6 months
• May 11, 2025

Tirzepatide for Type 2 Diabetes "Too many side effects when first taken, stomach pain, awful burps, fatigue, and body aches last 2-3 days. Need to be careful to eat small plain meals to survive."

• Tja...
• August 4, 2025

Tirzepatide "Severe stomach cramps and diarrhea lasting for several days. Over-the-counter diarrhea medication did not reduce the frequency or intensity of the diarrhea attacks."

• Dan...
• Taken for 1 to 6 months
• April 27, 2023

Tirzepatide for Type 2 Diabetes "I am experiencing stomach pain and constipation. I have had a weight loss of 10 lbs in 6 months. Insurance suddenly decided to not pay for it when I needed the next 2.5 mg increase in dosage."

• Ano...
• Taken for 1 to 6 months
• June 16, 2025

Tirzepatide for Type 2 Diabetes "Stomach pain and diarrhea. Severe indigestion, lots of burping and gas. My mouth stays dry."

• Jan...
• Taken for 1 to 6 months
• September 28, 2024

For Weight Loss (Obesity/Overweight) "Occasional stomach pain, diarrhea, or constipation. Never hungry."

• Ano...
• Taken for 1 to 2 years
• May 21, 2025

Tirzepatide for Type 2 Diabetes "Effective, had some nausea/vomiting and stomach pain the first couple of months, but then resolved. Have lost over 40 pounds over 18 months and A1C is 5.3. Very satisfied."

• Tri...
• Taken for 1 to 6 months
• December 9, 2024

For Weight Loss (Obesity/Overweight) "Was doing fine using a 2.5, raised me to five and then seven. Now, deathly sick. I felt like I was dying yesterday, stomach pain, fever, edgy sweats, was terrible."