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Tirzepatide and Loss Of Appetite: What Users Say (Page 3)

Brand names: Mounjaro, Zepbound

Reviews for Tirzepatide

Commonly mentioned side effects
  • Deb...
  • Taken for 6 months to 1 year
  • October 6, 2024

Tirzepatide for Type 2 Diabetes "I am coming up to a year. I've lost almost 40 pounds. Yeah for me! Side effects are loss of appetite along with feeling nauseous to painful arms. Other than that, my A1C when last checked was 5.3. My doctor said I now am normal in both my BMI and A1C. I am now on 7.5. The only bad thing has been the pain in my arms. Sometimes it wakes me up at night. I eat mostly protein and drink lots of water. Some days I do crave junk food, however, when I do, I eat it! Dot's Pretzels is my enemy. I have found that eating fruit after taking my shot helps with the side effects. But what do we do with the used pens? It's been a journey, but so far, doable. Good luck to all who are just starting!"

9 / 10
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  • Anonymous
  • February 22, 2025

For Weight Loss (Obesity/Overweight) "Great drug! Loss of appetite and no hungry feeling! I can eat something, but just a small amount, but no feeling of hunger. Really, an experience some constipation, but taking a laxative every other day, such as MiraLAX, took care of that problem. No side effects whatsoever other than that."

10 / 10
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  • PH5...
  • Taken for 6 months to 1 year
  • August 1, 2024

Tirzepatide for Type 2 Diabetes "I started on Mounjaro low dose in January 2024, which was gradually increased to 12.5 mg, with an A1C of 7.0, and my last A1C was 5.8 in June 2024, and I have lost 19 lbs. On this medication, my appetite has decreased, and I have been able to be more active."

9 / 10
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Frequently asked questions

  • Fat...
  • Taken for 1 to 6 months
  • October 13, 2024

For Type 2 Diabetes "Fantastic weight loss, lower A1C, causes slight nausea and feeling of fullness, and loss of appetite. Overeating causes nausea. Constipation, an additional side effect, easily counteracted by increasing fluid intake above 1.5 liters in 8 hours."

10 / 10
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  • L M...
  • Taken for less than 1 month
  • May 17, 2024

For Weight Loss (Obesity/Overweight) "Took my first dose on 5/10/2024, felt fine but did feel loss of appetite. By 5/14, that all changed. Woke up with terrible cramps, diarrhea, chills, and headache. So bad I had to call in to work. Now I don't know if this is what caused it but I was not watching my fat intake, busy with 2 birthdays and Mother's Day. Talked to the provider and they gave me a prescription for nausea. I felt good enough on 5/16 evening to work with one of my horses but today back at work with a gurgling stomach and belching. Can hardly eat because I'm afraid to. My dose was 2.5, provider wants me to wait a week or so and lower my dosage. I am truly afraid to take it, due to the effects I am having now. I had high hopes it would help me lose 30 lbs but not so sure anymore. Effective but not much fun to feel this terrible. Maybe just need my body to get used to it. Don't know, I may have triggered this by poor eating after the injection."

5 / 10
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  • can...
  • Taken for less than 1 month
  • July 29, 2024

Tirzepatide for Type 2 Diabetes "I started Mounjaro on July 19th, 2024. I started the medication because I was pre-diabetic, my A1C was high, and if I could lose a few pounds, it would be a plus. In my first week, I had the following side effects: nausea, loss of appetite, dry mouth, and some fatigue. I went to my doctor for a follow-up and had lost 5 pounds in my first two weeks. This was good, and I loved the weight loss. My A1C was 5.5, wonderful. Yet, I talked to my doctor about the fatigue. It had worsened to the point where my body didn't want to go up and down stairs. He suggested it was my sleep, however, my sleep habits hadn't changed. I'm planning to take Mounjaro 2.5 to see if the side effects lessen. Updates to come."

6 / 10
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  • gue...
  • Taken for 6 months to 1 year
  • May 31, 2024

Tirzepatide for Type 2 Diabetes "Brain fog, nausea, diarrhea, insomnia. Took 2.5 mg for 1 year, had problems with Kroger accepting savings card, so stopped. Really like having my brain back at full power... lost a lot of executive function while on Mounjaro. Have been off for a month. Blood sugar levels increasing, but not enough to put up with side effects. Appetite decreased after stopping (opposite of advertised effect)."

5 / 10
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More FAQ

  • Har...
  • Taken for 2 to 5 years
  • January 17, 2025

"Does work to lower blood sugar/A1C. Also works to lose weight. Over long-term use, it seems to allow for slight weight increase. Side effects include loss of appetite, fatigue, burps, stomach pain, nausea, and gastroparesis. After about two months of use, I developed an extreme sensitivity to touch. My skin became very painful all over, feeling like a mild sunburn with a horrible sensation of severe chills all the time. I am trying to tolerate the chills, but it is very severe."

8 / 10
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  • pat...
  • Taken for 1 to 6 months
  • May 23, 2024

Tirzepatide for Type 2 Diabetes "I used this for the first month at 2.5mg and did fine. Didn't really notice too much change and minimal impact on my sugar numbers. After 1 month, my doctor increased the dosage to 10mg. From that point, day 1 after my shot, I experience complete loss of appetite, chills, gastric pain. Days 2-4, I just had the loss of appetite and gastric pain, soft stools. Day 5 after my shot, loss of appetite, pain & diarrhea. The 6th day, some appetite back, less pain, no BM at all. Day of next injection was good, was able to eat more, no pain, normal BM. Day after 2nd shot at 10mg, is repeating again. I was losing some weight at the lower dosage but the sugar numbers weren't that much improved. On the higher dosage, I'm no longer losing weight but my sugars are more in line and coming down."

6 / 10
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  • BBr...
  • Taken for 1 to 6 months
  • May 1, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "I have had to stop. Cannot eat, close to vomiting, have lost 30 pounds. Dr. advised to stop, but I had already stopped 2 weeks ago as unable to eat. I was afraid to start the next box I had received. I am so weak I can barely walk. I do use a rollator to help me walk, but in the house I can hold onto furniture to help my balance."

5 / 10
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  • DeN...
  • Taken for 1 to 6 months
  • October 29, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "BMs are diarrhea daily, but only once or twice a day, so it's controllable. Losing weight, truly zero appetite, and when I eat, I feel full very quickly. No headaches or increased heart rate for me."

10 / 10
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  • RHj...
  • Taken for 1 to 6 months
  • October 23, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "Started 2.5 mg for 2 months, now started 5 mg with a significant decrease in appetite and 4.5% weight loss over the past 2 months."

8 / 10
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  • Shi...
  • Taken for 1 to 6 months
  • March 17, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "This is my second month taking Mounjaro. I haven't lost any weight yet. My appetite has decreased."

7 / 10
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  • ZRo...
  • Taken for less than 1 month
  • March 7, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "I just started my first 0.5 ml injection, and I am nauseous, no appetite, and I have upper body aches."

10 / 10
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  • JTJ...
  • Taken for 1 to 6 months
  • December 7, 2024

Tirzepatide for Type 2 Diabetes "Feel lethargic! Could sleep all the time. Not hungry."

9 / 10
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  • Zep...
  • Taken for less than 1 month
  • November 5, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "I have just started. I’m on my 2nd shot, going to the 3rd of 2.5, and my appetite has gone way down. I have lost 6 lbs so far."

10 / 10
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  • Der...
  • July 26, 2024

Tirzepatide for Type 2 Diabetes "Lost 22 pounds in 3 months. A1C went from 6.5 to 6.0 so far. Modest appetite suppression. You have to work with the drug, not against it."

9 / 10
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  • Lis...
  • Taken for 1 to 6 months
  • November 19, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "Very bad muscle stiffness and spasms in my hips and back. It’s like so much I started crying in pain and diarrhea. No appetite. Also can’t sleep."

5 / 10
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  • Nur...
  • Taken for 1 to 6 months
  • October 12, 2024

Tirzepatide for Type 2 Diabetes "2 months in, decreased appetite, constipation. Only plan to take it for three months, because I’m slowly changing what I’m eating so I don’t have to be on this long term."

8 / 10
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  • phi...
  • Taken for 1 to 6 months
  • September 20, 2024

Tirzepatide for Type 2 Diabetes "Definitely decreases appetite. Seems to have exacerbated depression. Very expensive!"

5 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • September 27, 2023

Tirzepatide for Weight Loss (Obesity/Overweight) "Lost 50 lbs. Decreased appetite has been the reason."

9 / 10
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  • lak...
  • Taken for 1 to 6 months
  • May 15, 2023

Tirzepatide for Weight Loss (Obesity/Overweight) "I have had side effects including a loss of appetite, loss of voice, constipation, blurry vision, headache, and tiredness."

7 / 10
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  • mot...
  • Taken for less than 1 month
  • April 11, 2023

Tirzepatide for Type 2 Diabetes "Extreme nausea for two days post-injection. Decreased appetite. On week two (5 mg/week) and have already seen a major improvement in my blood sugar levels, and I have lost 10 lbs."

9 / 10
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  • Fro...
  • Taken for 1 to 6 months
  • April 4, 2023

Tirzepatide for Type 2 Diabetes "On the second day of the increased dose, I started feeling tired, nauseous, burping, terrible taste, and not hungry. Hope this feeling ends soon."

8 / 10
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  • Mar...
  • Taken for less than 1 month
  • January 18, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "Stomach hurts with mild nausea. No appetite. On 2.5 mg subq. Hoping I will feel better after more time. Just started yesterday."

5 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.