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Tirzepatide and Loss Of Appetite: What Users Say (Page 2)

Brand names: Mounjaro, Zepbound

Reviews for Tirzepatide

Commonly mentioned side effects
  • Sus...
  • Taken for 6 months to 1 year
  • July 9, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "I used Mounjaro for 8 months. I went from 210 down to 100. It worked very well for me, almost too well. I have not taken it for over a month, and I am told I need to gain 30 pounds. My doctor took me out of work and sent me to a nutritionist and rehab. I am still losing weight even though I have stopped the medicine. My taste buds and appetite are still not back to normal. If you do take this medication, it does work, but be careful of losing too much."

10 / 10
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  • Tub...
  • Taken for less than 1 month
  • November 26, 2023

Tirzepatide for Weight Loss (Obesity/Overweight) "I’ve been taking it for 10 days. First days, severe indigestion, tiredness, and virtually no appetite. Now, no indigestion, appetite returned, but not as much as before. Which is the goal, right? So far, I’ve dropped five to six pounds, most in the first few days. I weigh myself each Wednesday and Saturday. If the last two days’ weight loss turns out to be routine, I figure to drop about 2 lb. a week."

9 / 10
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  • Car...
  • Taken for 1 to 6 months
  • May 31, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "I have been on the medication for five weeks, started on 2.5 mg and just increased yesterday to 5mg. Typical side effects include hardly eating because of no appetite, but I am not losing weight at all. I lost 2 lbs in five weeks. Started at 200 lbs and in five weeks only lost 2 lbs. Any advice please?"

6 / 10
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Frequently asked questions

  • Mar...
  • Taken for 1 to 2 years
  • September 6, 2024

Tirzepatide for Type 2 Diabetes "When I started in June 2023, my BS was 268, after one injection, it went down to 160. I am now on 12.5 mg, and my BS is 120-125. My A1C was 9, 2 months ago, it was 5.9. I have lost 100 pounds. I do feel that the 12.5 mg is not working very well as far as appetite suppression. Easy to use. I have always rotated in the stomach area, last week I did on the top of my thigh. I did not see a difference. No side effects since 5 mg, and then the side effects were not bad. I am not ready to move to 15 mg since that is the end of the line in mg's."

10 / 10
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  • Rwi...
  • Taken for 1 to 6 months
  • March 19, 2023

Tirzepatide for Type 2 Diabetes "My A1C and glucose levels are great. I am not on insulin. Side effects are rotten. Nausea, GERD, constipation/diarrhea, headache, stomach pain, decreased appetite every shot lessens over the week. Had this with Ozempic and Trulicity too, but not as severe. I have seen no weight loss benefit despite a decent diet and moderate exercise 3-5 times per week. Other side effects I’m not sure are related: feeling of lump in throat, slight face rash, occasional blurred vision, tingling in hands."

5 / 10
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  • She...
  • Taken for 1 to 6 months
  • March 17, 2023

Tirzepatide for Type 2 Diabetes "I started on Mounjaro 2.5 mg in January to get my A1C down, which was right at 8. I'm 61, and Metformin was horrible. I haven't had any side effects except for a decreased appetite. I don't overeat, and I really have to be really hungry to eat. I also get thirsty, but I love water, so being thirsty is no problem. At my three-month check, my A1C was 6.8, and all others were also good. Now moving up to 5 mg. I lost 18 pounds in 3 months, and I want to lose 22 more. Overall, so far, I have nothing but good things to say."

10 / 10
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  • Chi...
  • Taken for 6 months to 1 year
  • June 15, 2023

Tirzepatide for Weight Loss (Obesity/Overweight) "I have been on Mounjaro for almost a year. Started at 194 lbs, now averaging 145-150 lbs. In the beginning, I had the usual gastro effects - upset stomach, diarrhea, and no appetite even for water. Despite eating low calories, I lost slowly, about 1 lb a week. I had no energy to work out. If I tried staying on lower doses to minimize side effects, then the appetite would come back. After a few months, the gastro effects mostly went away, and I am left with sulfur burps, fatigue, irritability, and a general meh attitude about everything. I am someone who I would say has an addictive personality, and addiction runs in my family, and this drug works on your reward systems as well, so I’m not surprised it takes away my motivation. Despite the bad, it’s the only thing that has worked for me for weight loss. Currently, I take the injection every 14 days to minimize side effects and also to keep it affordable. Doing this keeps me at the weight I’m at, which I would like to be about 10 pounds less."

7 / 10
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More FAQ

  • Deb...
  • Taken for 6 months to 1 year
  • February 27, 2025

Tirzepatide for Type 2 Diabetes "Mounjaro has given me the best diabetic control in over 40 years. I am taking 7.5 mg, and it has reduced my appetite, meaning I have lost a small amount of weight, about 2 lbs a month. I am currently 3 lbs above the normal weight range for my height. Even with these amazing results, I still have to struggle to get my prescription. I have to email a request every 4 weeks to my surgery, as they refuse to put it on my repeat medication list. Other surgeries in the area give their diabetic patients the medication on repeat, so I am unsure why my surgery makes life so difficult."

10 / 10
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  • nal...
  • Taken for less than 1 month
  • February 24, 2025

Tirzepatide for Type 2 Diabetes "I am on a 2.5 mg injection. It's painless on injection. Just on my first dose, I lost my appetite within 2 days. I had gastric pains, but it was manageable. On day 3, significant reduction in changes on my belly fat was noticed. It is very costly, I paid R970 at Dischem. Medical aid doesn't cover it."

8 / 10
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  • Jot...
  • Taken for 1 to 6 months
  • January 15, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "In 2023, I became concerned when I gained weight, leading to me being 202 pounds. After my first Mounjaro shot, I felt appetite suppression immediately. Two days later, I made the mistake of eating greasy, cheesy pizza, leading to nausea, and I threw it up. Try to eat nutritious and less fried food on it. Also, I experienced severe cramps and diarrhea. It was just my first week, though, and I was notified that nausea and gastrointestinal issues are common for the first 1-2 weeks. It definitely gets better as your body gets used to it. As I have taken long gaps of 10-14 days in between doses, mild gastrointestinal problems still occur, but it’s definitely more manageable than before. Overall, I am very satisfied with this medication. I am much more in control of eating and don’t binge. I also lost 12 pounds in 5 weeks!"

10 / 10
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  • Lis...
  • Taken for 1 to 2 years
  • February 7, 2025

Tirzepatide for Type 2 Diabetes "Using this medication for over a year now, and at first, I experienced nausea and an upset stomach until I found that using different parts of the body to inject into may help with that, and bam, nausea gone. I had constipation, which was resolved with 1000 mg of magnesium. In the beginning, at my max dose, I had little appetite and ate to keep from getting low blood sugars. I lost 15 lbs and gained 20 back, but I didn't originally take the medication for weight loss, it was to control my type 2, which it has, so I can’t complain about that. My A1C is better and my blood glucose most days are normal. Now I just have to lose the weight I put on to feel comfortable again, which when I discussed this with my provider, she confirmed some people lose weight and keep it off, others will hit a plateau and gain some back once they hit their max dose."

7 / 10
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  • Kel...
  • Taken for 1 to 2 years
  • September 12, 2024

Tirzepatide for Type 2 Diabetes "Mounjaro worked well in the beginning. My BGL was lower, and I lost weight. After about 18 months, the control of my BGL was not as consistent. I experienced nausea and loss of appetite from the beginning, but that lessened over time. Recently, I have begun to experience severe diarrhea and belching for several days after taking a shot."

8 / 10
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  • Dav...
  • Taken for 6 months to 1 year
  • January 15, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "Unsure if the dose is too large. Severe decrease in appetite. Concurrent weight loss - 23 lbs so far. Weak. Tired all the time. Blood sugar in really good control, except for needing antibiotics to fight a severe cold and then flu. That has caused blood sugars in the 250 to 315 range. Strange lack of energy. Am on a 15 mg dose currently. Too much?"

8 / 10
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  • Luc...
  • Taken for 1 to 6 months
  • July 11, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "Love this medication and have lost 10kg in 6 weeks with a good diet and exercise. However, the side effects can be pretty intense. 2.5mg - sulfur burps, lethargy, flatulence, weight loss, decreased appetite, nausea. 5mg - sulfur burps, flatulence, abdominal distension, nausea, weight loss, chills, fever, headaches."

8 / 10
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  • Mar...
  • Taken for 1 to 6 months
  • November 19, 2022

Tirzepatide for Type 2 Diabetes "After month two, I’ve gotten a rash at the injection site. I immediately get a headache, much like a migraine, an hour or two after the injection. On day 2, I’m very tired and battle headaches throughout the day. On days 3, 4, and 5, I am nauseated and don’t have much of an appetite. On days 6 and 7, I’m extremely hungry, and then it starts like clockwork again. I don’t notice any weight loss, if so, it’s inches off my waist, but nothing too noticeable. I was on Ozempic 2 mg for 2 years and was switched to 7.5 mg of Mounjaro after the Ozempic shortage began in June 2022. Not sure if I should switch back at this point."

6 / 10
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  • Wai...
  • October 13, 2022

Tirzepatide for Type 2 Diabetes "I started on 2.5 mg and had a terrible time controlling my glucose levels. That dosage caused my A1C to raise from 5.4 to 6.1. Doc increased my dose to 5 mg. So far, no side effects except my blood glucose is still too high. A1C down to 5.9 and no weight loss you all speak of. This week, started 7.5 mg and started back on metformin ER 500 mg at night to control high BG 150 in AM. Immediately, over the last 2 days, I understand what you mean by no appetite. However, now my BG gets too low, 75 in the afternoons if I do not eat lunch. The scale is still not my friend. This balancing act is so frustrating. The good news is my next A1C next week will probably be back to my original 5.4 as long as I stay on the metformin. I doubt my diabetes doc will raise my dosage."

8 / 10
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  • M E...
  • Taken for 1 to 6 months
  • September 18, 2024

Tirzepatide for Type 2 Diabetes "I started Mounjaro 5 ml a month ago and lost about 11 lbs. I don't experience any bad side effects. Suppressed appetite to the point of aversion to food, a few bites, and feel full as if I had eaten a large portion. Looking forward to lowering my A1C and blood sugar levels, looking better (skinnier) is an extra benefit at this point."

9 / 10
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  • las...
  • Taken for less than 1 month
  • November 28, 2022

For Weight Loss (Obesity/Overweight) "I was placed on Mounjaro after a five-month-long (with some small breaks) stint to lose weight. For a reference point, I am in my twenties and weigh 280 lbs. I was constantly at the gym but saw zero lbs drop on the scale. I consulted my doctor and we decided to try this instead. I'm currently working through week 2, and so far, the medicine is working for me. I've lost five lbs simply by combining this medicine and consistent gym visits (4/week). The medicine itself suppresses the appetite, and I find myself fuller for much longer. I also don't have much desire for junky foods."

8 / 10
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  • Tir...
  • Taken for 1 to 6 months
  • May 23, 2024

For Weight Loss (Obesity/Overweight) "Diminished appetite, weight loss. I have been on both Mounjaro & tirzepatide for 6 months. Going slow to increase dosage with monitoring by healthcare is important. During the winter, I had bronchial flu & was prescribed 3 antibiotics & 3 rounds of steroids for 3 months. I regained some of the weight. I have not been able to get Mounjaro due to a shortage, so I found a local health/diet clinic to begin the tirzepatide again. Diet & exercise are key for assisting the tirzepatide to work properly. I wish insurance/medicare assisted in the payment, but it’s worth getting my BMI out of obesity range."

10 / 10
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  • TIN...
  • Taken for less than 1 month
  • June 15, 2023

Tirzepatide for Type 2 Diabetes "I am two injections in, third one tomorrow. I have occasional nausea during sleep, but only if I ate more than I should or if I ate something sugary (still learning the ins and outs), lots of burping, and a decreased appetite. Have lost 7 lbs so far, and my blood sugar has been much easier to control."

10 / 10
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  • Isa...
  • Taken for 1 to 6 months
  • September 18, 2024

For Type 2 Diabetes "Started 2 months ago. First month on a low dose and then increased to 0.6. I do not have any major side effects unless you count no appetite and not wanting to eat a side effect. I have never thrown out so much food because I just do not want to eat, and when I do, it is a small amount. Since I started, I have lost 5 kg, which is a major thing for me as I have been 105-107 kg for the past 3 years. I especially like the fact that I only need to inject once a week. My previous injectable was daily and made me feel nauseous."

10 / 10
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  • Mjg...
  • Taken for 1 to 6 months
  • November 19, 2024

Tirzepatide for Type 2 Diabetes "I have been taking Mounjaro for almost three months, increasing the dosage each month according to my doctor's prescriptions due to my Type 2 diabetes. I have experienced dizziness, constipation, lack of appetite, blurry vision, and nausea after eating a meal. None of the side effects I've experienced have been severe enough to warrant discontinuing Mounjaro. My A1C has dropped from 8.5 to 6.3, and I have lost 30+ pounds since starting Mounjaro. I have not experienced diarrhea, vomiting, or pancreatitis. I am pleased with Mounjaro, which has resulted in weight loss and diminishing A1C levels."

10 / 10
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  • dee...
  • Taken for 1 to 6 months
  • November 30, 2022

Tirzepatide for Type 2 Diabetes "I have been on Mounjaro since Sep 2022. I started off with the 2.5 mg for about a month with no issues. My provider then moved me to 5 mg in October. Once again, no issues, and I started losing weight. 15 lbs in about 6 weeks. I was then moved up to 7.5 mg in November and have been miserable ever since. I have no appetite, severe constipation, major headaches, and vomiting, and I am now having issues with low blood pressure (causing lightheadedness, dizziness, and vision issues), which I believe is being caused by my never wanting to eat or drink anything. I have informed my provider of this, and she is now wanting to send me to a cardiologist to make sure my heart is working properly. She has also decided to lower my dosage back to 5 mg. I am hoping this change helps because so far, my type 2 diabetes is under control, and my sugars have been fantastic!"

7 / 10
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  • Lau...
  • Taken for 1 to 6 months
  • October 5, 2024

Tirzepatide for Type 2 Diabetes "My first shot (2.5) was 7/11/24. Had a 2-week interruption due to availability and doctor/pharmacy miscommunication. After the interruption, I was on the 5 mg and have now been taking it for 14 weeks. After one month, my A1C went down to 6.5, and I can't wait to see what it will be when I get my next blood work in about 3 weeks. My FBS has been consistently below 100! Losing weight is just a bonus to me - started at 203 pounds and I'm now down to 183 pounds. I've had no ill effects (I don't really consider loss of appetite as a bad side effect). I eat when I'm hungry until I'm no longer hungry, and I'm not interested in snack/junk foods. Win/win! I try to eat healthy (minimal processed foods) and exercise every other day on my stationary bike and upper body weights/resistance bands. At 61, I think I'm healthier than I have been in ages."

10 / 10
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  • me5...
  • Taken for 1 to 6 months
  • April 2, 2025

Tirzepatide for Type 2 Diabetes "Had to stop taking after 7 weeks of use. Total loss of appetite, very weak. When I try to eat, cannot do it due to gagging. The smell of foods upsets my stomach. Getting scary now, haven't used Mounjaro for 2 1/2 weeks and no improvement. No energy at all, hard to function."

3 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.