NP Thyroid and Depression: What Users Say

• Eli...
• Taken for 6 months to 1 year
• November 6, 2019

For Underactive Thyroid "Do not take this medicine! Started in July. He gave me samples first. Those were good. Did blood work again, doubled dosage and got script in August. My hair dried out and started falling out. Then insomnia, anxiety, panic attacks, depression, crying for no reason, menstrual cycle irregular, throat burning, stomach hurt, headaches, very greasy, complete brain fog, itchy with bumps, could barely talk, bad back shoulder and neck pain. Barely functioning day to day, I felt empty inside, like I was losing it. I couldn't talk right. I was waking up at 12 am wide awake, couldn't relax, completely amped and exhausted at the same time. I didn't understand what was happening. I stopped taking it. Every day my brain got clearer and felt more like me, my personality came back. I have always been healthy and didn't look at the side effects. I feel stupid for not, lesson learned. This isn't ok! I'm so glad I found this site and it all makes sense now. Please report this! I am!"

• Anonymous
• October 28, 2019

For Underactive Thyroid "I have been taking NP Thyroid for about one year now since NatureThroid became unavailable in 0.5 grain. It's been okay but the last two months I have begun feeling horrible. I have no energy, feel very tired, digestive problems, bloated painful stomach, headaches, brain fog, leg cramps, anxiety/panic attacks, depressed, complete loss of libido, fat gain around the middle, and more. In early September, I noticed my NP Thyroid refill smelled horrible. I contacted my pharmacist and he told me batches vary - it's normal. So I continued to take it, feeling worse over time. I stopped taking it for 3 days as a trial this week and felt somewhat better. I since found a few websites and blogs that discuss the issues. I am not alone. Will contact Naturopath tomorrow to see what my options are. I too, like others, feel poisoned. It seems like my reaction is more than just hypothyroid symptoms. I did not feel this badly before starting thyroid hormones."

• Jas...
• Taken for 6 months to 1 year
• April 11, 2020

For Underactive Thyroid "I've been on Armour Thyroid for years and felt fairly good. My doctor switched me to NP Thyroid recently because Armour is no longer covered by insurance. NP Thyroid is awful. Not only did it cause some thyroid symptoms to return (trouble waking up in the mornings, extreme fatigue, depression, weight gain, and irritability to name a few), but it also caused new symptoms. My stomach hurt a lot with acid reflux symptoms, and I had constant mucus in my throat, which created a chronic cough, to the point where I had to clear my throat every 15 minutes. After being back on Armour for a couple of weeks now, all of the symptoms/side effects have disappeared, and I feel good again."

• Sel...
• Taken for 1 to 2 years
• December 20, 2019

For Hashimoto's disease "This medication has done wonders for me, good and bad. My energy level went up, and I lost a ton of weight. I’m actually underweight now. But over the past month, my mental health has suffered greatly. I’m so depressed and anxiety-ridden. I blow up over everything and just feel utterly hopeless. It’s scary how much I don’t care about anything anymore. Is there anyone else that feels this way? I honestly don’t know if it’s my regular life stress or this medication."

• PM ...
• Taken for 1 to 6 months
• December 1, 2019

For Hashimoto's disease "If I could list -1 as a rating, I would. Proceed with caution with this medication. I did not know what was happening to me until I spoke with two mutual friends over the holiday weekend. The confusion, depression, exhaustion, unable to sleep, and rapid heartbeat are the short list. I started NP Thyroid in May of 2019 and reached out to my doctor to switch me back to my RX in October. I've been on my old script for less than a month, but my symptoms are still present. Gained 15 lbs quickly, and joint pains are overwhelming. My life has been affected! Be careful... please!"

• Lym...
• Taken for less than 1 month
• October 20, 2020

For Underactive Thyroid "Started taking NP Thyroid about 3 weeks ago. I was taking WP Thyroid due to recall, no longer available. I have chronic Lyme and co-infections. I've been feeling a lot better lately. About 2 weeks ago, I started feeling very anxious, heart palpitations, extreme fatigue, severely depressed, brain fog, muscle pain/aches, and the list is endless. I really thought it was one of my co-infections coming back. Paid $580 to get tested for it, and I was negative. Couldn't figure out what was causing all of this until I Googled NP Thyroid, it smells like cat pee. I will no longer be taking it. I don't know what to change it to, I see my doc on Monday, I hope to get it sorted. Please don't touch this stuff."

• Ame...
• December 4, 2018

For Hypothyroidism, After Thyroid Removal "Like most with the WP/Naturethroid shortage, was switched to this drug back in 2017. On it 4 months; 120 mg/2 grains in the am, and 30 mg/a half grain in the afternoon. Managed to get back on Naturethroid right when it became available again in early 2018, not the greatest as they reformulated it and my levels were low, but at least no side effects. When my prescription for it ran out recently, I had no insurance to see my doctor again yet, and so had no choice but to take something I already had on hand. This time, after 6 hours of taking the first dose of NP, I experienced the most profound sadness/deep depression, complete with crying spells. It lasted for hours; I was in bed crying my eyes out for no apparent reason. Not like me! And that’s not all. Headache, dizziness, anxiety, heart pounding, feeling like I was going to pass out, diarrhea, vision problems, confusion/disorientation/brain fog, no appetite, “wired but tired” feeling, shortness of breath...what a list, good grief!"

• Ame...
• December 4, 2018

For Hypothyroidism, After Thyroid Removal "Like most with the WP/Naturethroid shortage, was switched to this drug back in 2017. On it 4 months; 120 mg/2 grains in the am, and 30 mg/a half grain in the afternoon. Managed to get back on Naturethroid right when it became available again in early 2018, not the greatest as they reformulated it and my levels were low, but at least no side effects. When my prescription for it ran out recently, I had no insurance to see my doctor again yet, and so had no choice but to take something I already had on hand. This time, after 6 hours of taking the first dose of NP, I experienced the most profound sadness/deep depression, complete with crying spells. It lasted for hours; I was in bed crying my eyes out for no apparent reason. Not like me! And that’s not all. Headache, dizziness, anxiety, heart pounding, feeling like I was going to pass out, diarrhea, vision problems, confusion/disorientation/brain fog, no appetite, “wired but tired” feeling, shortness of breath...what a list, good grief!"

• Peg...
• Taken for 2 to 5 years
• January 15, 2020

For Underactive Thyroid "I cannot take Synthroid, so years ago, my doctor switched me to Armour, and it worked great! Then, for a year, they stopped making it. I started on what is called just Thyroid in Canada, made by Erfa. It worked beautifully. Then, after about 3 years, it went south on me. Tried Armour again, and it was not good for me anymore. I have been on NP for 3 years, and this fall, I was depressed, anxious, I’d get angry. I couldn’t figure out what happened. Never thought of it being NP until 2 weeks ago. I found out they no longer manufacture the pill in Georgia, but it is now manufactured in Europe, but no one knows where. I stopped the pill for 3 days and felt so calm and actually really good. Then, I started on a half dosage for 4 days and felt good. Today, I took a full dosage, and I feel a little weird, but not like before. My doctor wants me to see an Endo ASAP, which I will after giving this a few more days. If they change any filler, then that’s what we get the symptoms from."

• Anonymous
• Taken for 6 months to 1 year
• February 19, 2021

For Underactive Thyroid "I have been on Nature Throid for years and have felt great. My doctor switched me to NP after Nature Throid was recalled. I felt okay at first, and now symptoms are popping up: sore arms, depression, constipation, brain fog, weight gain, puffy skin, and fatigue. This medicine isn't consistent, and not to mention, it smells and tastes like pee. Stop recalling medicine that works for people for pharmaceutical benefit. It's wrong. This stuff is junk."

• Anonymous
• August 16, 2018

For Hypothyroidism, After Thyroid Removal "I never write reviews, but want to share my experience with NP Thyroid by Acella. I have many of the same problems listed here already. I have taken thyroid replacement for 20 years. I had been on Armour for years; my dosage is closely monitored as my blood levels fluctuate a lot. My doctor switched my dosage, and the pharmacy filled it with the generic NP Thyroid instead of Armour. We have new health insurance. I decided to try it; maybe it would help keep my levels more steady. Three weeks in, and this is the worst I have ever felt mentally. I have never been so depressed in my life. I have dealt with anxiety, but this is different: hopeless, weepy, with a dark depression. I have gained over 10 pounds, and all I want to do is sleep. The confusion and brain fog are almost scary; I can't remember or figure out simple things I do every day. Maybe if I could give it more time, my body would 'adjust,' but I had to call my doctor to go back to Armour. There is no way I could take the NP another day."

• Ann...
• September 22, 2019

For Underactive Thyroid "NP Thyroid was prescribed for me for the first time, so I have no other meds to compare to. The first 4 days, energy, positive weight loss. 2 weeks, my hair feeling dry & breaking. Shortly after this, hair is falling out from the root in GREAT amounts! I have fine hair and really cannot lose anymore. My doctor said to cut my 30mg dose in half. This didn’t help, my hair continued falling out. Finally, she said to go off completely. I was on this for one month, 5 days. After going off, I got weepy, depressed, and felt worse than before I started. It’s been 15 days since stopping the NP, and my hair isn’t falling out as much. I’m not feeling as weepy anymore. I have some weird dry bumps on my scalp that just started since this med, and I have a dermatology appointment for that next. The pills smell like urine. I thought that was normal as well. I am going to be very apprehensive about trying another medication. But for now, still dealing with the aftereffects of this horrible medication."

• TDB...
• Taken for 1 to 6 months
• April 4, 2023

"Horrible medication. I experienced pelvic pain, water weight gain, severe joint pain in my knees, depression, mania, puffy face, profuse sweating, headaches, and bloating. I also had abdominal pain and major chills. I went back on Armour…willing to pay more money. This drug is horrible, the worst experience of my life!"

• Dor...
• Taken for 1 to 6 months
• February 8, 2019

For Hypothyroidism, After Thyroid Removal "Walmart pharmacy substituted NP for Armour thyroid. It makes me very depressed, sleepless, and fatigued. It makes me angry because they did this without my permission after I told them before that I didn’t want NP because of the same issues before. I would avoid NP!!!!"

• Tin...
• Taken for 6 months to 1 year
• September 4, 2018

For Underactive Thyroid "NP Thyroid med makes me feel very depressed. Very emotional, dizzy, feel like I'm dying. I can't sleep. Always hurting all over my body. Urinary tract infection out of nowhere. I'm going to the doctor ASAP to tell him to get me off these meds."

• Kri...
• Taken for 6 months to 1 year
• August 2, 2019

For Underactive Thyroid "I have low T3 syndrome. NP Thyroid is the only thyroid medicine that works for me and my family. I'm not sure what is causing our T3 to tank out, but so far this is the only thyroid medicine that works, and it's like a night and day difference for us. I have energy, I sleep, joint and chest pain have stopped, and depression symptoms have lifted. I would recommend anyone searching for thyroid medicine to try one until their symptoms change. My numbers became 'normal' with other thyroid medicines, but this is the only one that fixed my actual symptoms."

• EBa...
• December 29, 2020

For Underactive Thyroid "Armour Thyroid for many years with no issues. Armour became difficult to get, and a couple of years ago my doc switched me to Nature Throid. I had no issues. About a year ago, my prescription was filled with NP Thyroid. Since then, I've had horrible body aches, brain fog, depression, and bad anxiety. I literally thought I was going crazy! I've always been happy and outgoing. After many, many days of researching, I found comments and reviews that stated people on NP Thyroid feeling the same way I was. I've now been off all thyroid medication for over a month, and while tired, constipated, and other normal hypothyroid symptoms, I feel better. No longer crazy, anxious, and depressed. My body hurts some, but nothing like when taking this stuff. My doctor has now prescribed Nature Throid again, and I will start it tomorrow. I'm looking forward to getting my life back, laughing again, and being able to think and function. Stay away from NP Thyroid!!!!"

• Lor...
• Taken for 1 to 6 months
• July 22, 2022

For Underactive Thyroid "I started taking NP Thyroid in June. For the first week, I felt great, but then I started to notice some of the pills had a terrible odor, and the taste was worse. I have cats, and they smelled like cat urine, as well as my urine. Not every pill had the odor, but the ones that did, that I took, caused me terrible stomach cramps. Then, as time went on, my hair loss was terrible, constipation was 5 days, anxiety, depression, severe fatigue, it all came back as well as hot flashes. I let my doctor know, and he wanted me to have blood work before he made any changes, so after 5 weeks, I had blood work. I got it back, and my T3 was high, TSH low, and T4 was good. Before the blood work, I had blood work done, and the levels I just mentioned were all in range. I stopped it immediately. Unfortunately, my doctor is on vacation, so I can't get any meds like LDN, which worked wonders for me in the past. I am so exhausted I can barely function. I would not recommend this medication to anyone."

• Ang...
• Taken for 1 to 6 months
• April 17, 2021

For Underactive Thyroid "Been taking this for two months. It's been a nightmare. Tired all the time. Massive weight gain. Lack of motivation. Aching legs. I've tried almost every thyroid med available. The only worse was Synthroid."

• Lan...
• Taken for less than 1 month
• March 10, 2021

For Underactive Thyroid "I could only last 10 days on NP Thyroid. I became so much more exhausted I couldn’t get myself out of bed. Increased brain fog. Increased headaches. Increased depression. Increased water retention. Stomach became bloated and developed constipation. I’ve been off of it for 5 days and still feeling off. I’m very sensitive to drugs, but this has never happened to me with other thyroid medications."

• GST...
• Taken for 1 to 6 months
• October 28, 2022

For Hashimoto's disease "Terrible med. Unbeknownst to me, the pharmacy gave it to me in the place of Armour, which I have been taking for years and works great. I took NP Acella for about a month and a half, and all of my symptoms came back with a vengeance. I gained weight, became fatigued and depressed, started losing hair, couldn't sleep at night, had brain fog, etc. Went back to Armour and was fine again. If I could, I would give NP Thyroid Acella a 0. Also, I wish pharmacists warned us when they replace a prescription."

• Lin...
• Taken for less than 1 month
• August 29, 2018

For Hashimoto's disease "I just discovered that the pharmacy substituted my Armour with NP. I have been feeling depressed and having brain fog shortly after switching, and now I know why. This stuff is garbage!"