User Reviews for Durolane to treat Osteoarthritis

"I had an injection of Durolane on Sept. 2, 2020 and it is Nov. 8, 2020 now. (2 months, 6 days) I am in horrible pain and can not stand the pain when I stand up, cannot rest at night because of so much pain. I have taken low dosages of Prednisone and taking Tylenol and get hardly any relief. I cannot take any pain medicine other than Tylenol. Will this pain go away eventually? What has others found that caused this to happen and what have they done to get help. I have seen an orthopedic and he does not seem to know what to do and does not understand what has happened. Please anyone, can you give me any encouragement? I am desperate..."

"This year my insurance changed and decided I no longer needed the synvisc-one injections that I had been getting for the past 3 years. They would only approve Durolane. I had never tried it and and assumed it was an equivalent to the other. Boy was I wrong!! I wish I had done my research before getting it. I received the injection in my right knee and immediately was overcome by excruciating pain that radiated throughout my whole leg. I was in so much pain and it would NOT stop. My knee instantly swelled and ceased up. After an hour of sitting in the Dr.'s office, I had to get my husband to come pick me up from the appointment. I couldn't even get my clothes back on. I could not put weight on that knee for a week. The pain is worse now than before the injection. I do NOT recommend this drug."

"Got the injection in my left knee (has Patellar Chondromalacia) yesterday around 11:00, was fine until the Lidocaine wore off. I haven’t been able to walk since yesterday at around 3pm. Really wish I had researched and seen these reviews, I would’ve NEVER gotten the injection. I’m also an Emergency Department nurse, I don’t know how I’m going to work when I can’t even walk! I’ve been icing, elevating and taking Motrin....miserable!"

"I would not recommend this drug to my worst enemy. I had slight pain and periodically had the Hyaluronic doses administered in 3 separate doses. Although I request this again, they said it was better to get the Durolane which s one quick dose. As a result of getting this injection, they pain from it was excruciating. It never left, waking me every night with severe pain. My mobility is worse now. I cannot say anything positive about this drug! I would rate it as a 0 on a scale of 1-10 with the 10 being the most effective."

"If only I had seen the reviews for Durolane, I would never have agreed to its injection into my right knee. Despite my hopes for relief, I am still waiting for it to take effect, even though it has been two months since the procedure was done on January 22, 2023. The pain is excruciating at night and debilitating during the day. I have found some temporary relief by massaging the area with Arnica cream, but I am still hopeful that the medication will eventually kick in and relieve the pain. Additionally, I have used KT Tape, which has allowed me to walk a bit more comfortably."

"It’s one week out since my Durolane shot in my knee. At the time of injection it was a little more uncomfortable than a steroid shot. I was ok for two days afterward, then the terrible pain started and has not stopped. I can hardly walk or stand for very long. Very disappointed and discouraged by this injection and upset I wasn’t warned by my physician. I’ve been icing it and sitting a lot, and it’s more painful at night, so sleeping has not been easy. I would never get this injection EVER again. This has been my honest experience and just wished I had read the warnings from these reviews first."

"Stay away! Had an injection in my hip in Oct 2020 and it’s been a literal nightmare ever since. Going on month 6 and I still have a ton of pain and struggle to walk more than 10 mins without pain. My hip is 100% worse than before the injection. I have deep deep regret that I chose to take the injection. I’m 48 and was in very good shape prior to this (I have a slight labral tear) and have not been able to train since. Completely depressing. My doc sent me for an MRI that ended up showing nothing of consequence. This really really affected and continues to affect me very negatively. I would give a negative rating if possible."

"I had a Durolane injection in my knee that was injected using Ultrasound guidance so it went straight into the capsule of my knee and I must admit it feels amazing! I was a bit put off by these reviews but from what I can understand is that the Durolane will hurt if it isn't injected in the right place as it is so thick. This is why I would recommend it being injected using Ultrasound guidance!"

"I have received Monovisc and Gel One injections having extremely positive results with the Monovisc. Duralane was injected in my knee I thought it was Monovisc and I have been in unrelenting pain ever since! This drug seriously needs to be discontinued. DO NOT LET ANYONE INJECT YOU WITH DURALANE! I am crippled now. Before I have reasonable mobility. This is a disaster."

"In my opinion this stuff should be outlawed. I would rate it a MINUS-5 after 7 days. After getting Durolane in both knees I could hardly make it to the car. The first 2 days I could barely make it to the bathroom using a walker. The next 5 days I am getting around with way more pain than before the injections. I have had over 40 Synvisc injections in both knees and they all had positive effects."

"I had both knees done and I have had THE WORST pain ever I can hardly walk. My doctor suggested it would take a few weeks for it to work. It has been two weeks no change except more pain. When will the pain stop?"

"Had this injection a month ago ....absolutely useless. Did nothing for my right knee, still in acute pain. $500.00 down the drain. Really think about this, wish I had, but pain was so bad, would try anything for relief. It might work for you, but certainly not for me."

"I had the Durolane + steroids injection 5 days ago injected into both knees. I felt relief immediately and had no problems. I have been without pain since then, I can walk, stand and sleep much better and I feel amazing. I am very happy with the results of this injection and hope they last long."

"Had Durolane injections 2 weeks ago. I have experienced the worst pain I’ve ever had. Could not walk into the house on my own. Pain is especially bad at night. Feels like I have hot coals in both knees. Would never recommend these injections."

"I had Durolane injection in both knees yesterday. I have a headache so bad. I feel sick to my stomach, my left knee is larger and hard from the top of my knee and down, he drained it yesterday as well. I don’t know what to I wish I didn’t get it. This is the worst feeling. If I feel the same tomorrow I will call the Drs office again. My right knee is very sore. They feel like someone is hitting me in the knees with a hammer, not stopping? I hope it’s not a blood clot. Idk . I can hardly walk. For me day 2 it’s terrible, thank you for letting me tell my experience"

"Please do NOT use Durolane. I had moderate pain in right knee and was recommended durolane and had the first injection in January 202. Now , end of March the pain is worse than ever. You would be better off just burning your $500 in the fire place. YES this company should be sued for the agony it has caused so many people. I wish I had the reviews first. BEWARE"

"Day three after my first Durolane shots in both knees. Right knee, no problem. Left knee, pain with some swelling for two days. Now feeling great! I am excited to see how the next few months go. Word of advice...ice, elevate and Aleve. Rest for 48 hours...it’s worth it! Good luck"

"I had both knees injected on Feb 7. I have had synvisc injections 3X's over the past 5 years. The doctor suggested durolane. She said, it would be one injection instead of 3 like the synvisc. The synvisc had worked great for me. Since she said it would work the same, I agreed to do it. The pain was unbearable!!!!!! When I left the office, I could barely walk. I had to keep my hand on the wall to maintain my balance. When I got home, it was very difficult to walk up and down the stairs. I can't believe they allow this injection to be used. It's been almost 5 months and I'm still having difficulty walking. I have a tingling feeling above the knee and in my foot. I'm sure there is going to be some lawsuits over durolane. This should never be used on anybody!!!!"

"Upon reading all of the negative reviews, I chose not to have the injection. The following day I thought.... this is my only chance at having a better life! Well thank GOD I manned up!! I just had the shot a couple hours ago. The injection was OK 2/3 through but at the final 1/3 it did get a little uncomfortable but I knew things could only get better after this ! I say GO FOR IT! Better off giving it a shot Lol. Than to wonder if it would have...."

"I had one injection in each knee. The first 48 hrs I rested and limited movements. No pain nor swelling from injections. My left knee had been really painful 5-6months before treatment. Both knees are bone on bone. The pain from the stress on the left knee is subsiding daily now. I'm having to learn to walk normal again but I am so happy I had the injections. I will be having knee replacements sometime next year but this will give me time to loose weight and get my legs back in shape."

"Got the Durolane injection in my right knee then 5 days later I’m in the Er with an infection and now have to be on infusion antibiotics 3 times a day via a pic line for the next three weeks. I Would NOT recommend This drug!"

"Supposedly Durolane is artificial hyaluronic acid used for those of us who are allergic to eggs. Had a shot and could not walk our of the doctor's office. The pain was the worst I have ever had and I have severe OA in both knees, which in itself is a lot of unending pain. That knee now has a whole lot more excruciating pain. Can't recommend it because I think it harmed my condition."

"It's been 8 months to the day that I had both knees injected with Durolane. Walking and going up and down stairs is still very difficult. This has weaken my knees and leg muscles. My leg gives out now and then. My balance is off. I can't run. Who ever approved this should be sued and jailed!! My quality of life has dropped drastically. I'm 71 and can't play with my grand kids like I use to. It's like I'm 10 years older. I don't know what to do about this now!!!!! I'm giving this a 1 because I can't give a negative#"

"Today is Day 5 after my injection. I really regretted the decision on days 1-4. Yesterday was particularly bad with one of my knees buckling every few steps. Today I have no pain and I am greatly relieved. Apparently, the internal swelling caused the nerve pain. Swelling is gone and pain subsided. Yeah!!!"

"I got the Durolane injection on Tuesday of April 14,2020 and when I was walking out of office after shot it felt good, but by time I got home it hurt some. Everyday I get up ok but by lunch it hurts some by evening it gets worse and then last night April 16,2020 was the the worst ever. I tried ice it and heat, and finally a Toradol pain reliever. I was able to wake up ok but it has been bad all day today . It says give it two weeks to fully feel the effects. Am bone on bone and a lot of arthritis in my knees . I pray this works"