Sitagliptin and Vomiting: What Users Say

• Anonymous
• February 6, 2017

For Type 2 Diabetes "I have been on Januvia for about a year and a half. My A1C went down from 9.0 to 8.0. However, I have developed nausea, dizziness, vomiting which I never know when it will hit. Had colonoscopy and they found nothing. In the last six months, developed numbness in my right arm and hand, reflux which keeps me up at night, constant urination about every 45 minutes, and fatigue (this has added three more pills to my daily intake for those symptoms). Told my doctor, and he said to keep taking Januvia and that I was not getting any younger. However, I read here that others have similar side effects once on Januvia."

• XYD...
• July 28, 2016

For Type 2 Diabetes "The side effects of 50 mg Januvia with Metformin ER were horrendous. Painful finger joints. Swelling fingers. Stuffy ears. Unbelievable dizziness, which caused nausea and dry heaves. The diarrhea has been so awful that I can't leave home. I stopped the Januvia 4 days ago. The dizziness stopped first. Then my hands settled down. The diarrhea has not stopped. My doctor believes that I have parasites because Januvia, in conjunction with Metformin ER, doesn't cause diarrhea like this. Getting tested tomorrow, and I have to go back on Januvia. Not looking forward to this at all. What a mess."

• Ins...
• Taken for 6 months to 1 year
• November 17, 2019

For Type 2 Diabetes "I was diagnosed with diabetes a few years ago and was given Metformin. Immediately, I had severe stomach pains, nausea, and vomiting. I was switched to Amaryl (dropped my blood sugar constantly), then to Oseni (which worked miracles with the right diet). Then there was a shortage, so I was prescribed Januvia! Januvia doesn't drop my blood sugar if I haven't eaten in a while, and I don't have to be as strict with my dieting (no pasta with Amaryl and Oseni vs. pasta with Januvia). With Januvia, my A1C was at a 6.5, and I didn't have any nasty side effects. Januvia is the only medicine I'm on right now for my diabetes, and I'm actually glad my doctor fought to get me the medicine."

• Har...
• Taken for less than 1 month
• April 22, 2018

For Type 2 Diabetes "Terrible drug worked okay the first few weeks, then I began developing the most severe diarrhea and dysentery. I would spend 3 or 4 days glued to the toilet, going through 20 to 30 pairs of underwear (diapers). I was pooping in my sleep in bed. The dysentery went away when I discontinued the pills but came back immediately when I resumed taking them. Became dehydrated, shortness of breath, sweating, dizzy, vomiting, dry heaves, and felt weak. Severe stomach cramps ended up in the ER room with an IV drip of morphine to stop the pain. I almost died."

• Har...
• Taken for less than 1 month
• April 22, 2018

For Type 2 Diabetes "Terrible drug worked okay the first few weeks, then I began developing the most severe diarrhea and dysentery. I would spend 3 or 4 days glued to the toilet, going through 20 to 30 pairs of underwear (diapers). I was pooping in my sleep in bed. The dysentery went away when I discontinued the pills but came back immediately when I resumed taking them. Became dehydrated, shortness of breath, sweating, dizzy, vomiting, dry heaves, and felt weak. Severe stomach cramps ended up in the ER room with an IV drip of morphine to stop the pain. I almost died."

• Hol...
• Taken for less than 1 month
• March 29, 2022

For Type 2 Diabetes "I'm 75, weigh 138, 5'10', A1C 6.2 - 6.7 with 2 mg Glimepiride + 2000 mg Metformin. Dr. switched me to Januvia 100 mg + 2000 mg Metformin. Blood sugar went out of control from day 1. Over 200 daily average (I test 7 times/day). Morning fasting went from 115 to 226. Nine hours of vomiting and diarrhea on the second day. Nauseous every day for two weeks. Lost 5 lbs in two weeks--I need to gain weight. Stopped after day 14. Very bad drug for me. Dr. now wants me to try another miracle drug: Farxiga. Don't think so as I will need a loan just to buy it."

• Anonymous
• Taken for 6 months to 1 year
• May 27, 2023

For Type 2 Diabetes "When used with Metformin, I had stomach pain, diarrhea, vomiting, nausea. Without Metformin, I now have a constant backache, leg swelling, increased appetite. I was losing weight before, now I am gaining it back while sticking to my diet. My dosage is 100 mg, once daily, and my blood sugar is still not under control."

• dia...
• Taken for less than 1 month
• May 23, 2023

For Type 2 Diabetes "Just started taking Januvia, and I am feeling nauseous and having dry heaves."