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Sitagliptin and Insomnia: What Users Say

Brand names: Januvia, Zituvio, Brynovin

Insomnia: mentioned by 7 users (4.5%)

Based on user experiences from 154 Sitagliptin reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

diarrhea 11.7%
joint pain 9.1%
nausea 7.1%
upset stomach 5.8%
shortness of breath 5.2%
swelling 5.2%
vomiting 5.2%
back pain 4.5%
constipation 4.5%
insomnia 4.5%

Reviews for Sitagliptin

Commonly mentioned side effects
  • Anonymous
  • December 1, 2008

Sitagliptin for Type 2 Diabetes "While I was on Januvia it felt like I was on a high-power diet pill. I did not go to the bathroom but once in 5 days, had bloating and stomach problems, and it felt like my hormones were out of whack. I could not sleep. This is my second day off Januvia, and I can't wait to go home and sleep tonight. All of the not sleeping is finally catching up with me. I hope when someone else tells their doctor about this, you don't get the look like I got. Hope this helps someone."

2 / 10
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  • Ozz...
  • Taken for 1 to 2 years
  • January 6, 2013

Sitagliptin for Type 2 Diabetes "If I would be more compliant with my diet and exercise regimen, Januvia would help me stay under 6. No noticeable side effects, although after reading other reviews, possibly the lack of sleep might be attributed to it. I had some joint pain but I take CoQ10 and that made it go away. Not sure if that was from Januvia or the statins. Overall, I like it. Can't wait until, with better compliance, I can come off these costly medicines."

9 / 10
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85 Report
  • wra...
  • November 6, 2016

Sitagliptin for Type 2 Diabetes "Januvia caused me severe muscle cramps, bad enough that I should have gone to the hospital because of the pain. I also got where I could not sleep at night while on Januvia. It was also not effective for me. I was placed on Invokana in addition. I am still having side effects after stopping both of these. My doctor did not even bother to return my call when I took myself off of Januvia. Because the spasms are in my neck-shoulder area, it has caused me to drop 40 pounds off of my weight lifting workout. This is not good. I would encourage anyone considering Januvia or Invokana to do research on the side effects because my side effects were not common, but the drug company lied to doctors about all of the side effects."

2 / 10
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53 Report

Frequently asked questions

  • bul...
  • August 8, 2009

Sitagliptin for Type 2 Diabetes "I'm taking Metformin and Glipizide. That was not getting the numbers under 7, so the doctor added Actos. I gained 20 lbs in 3.5 months. The doctor has switched me to Januvia instead of Actos. Only second week, but side effects have been minimal (some sleep issues). The big thing is no longer feeling hungry all the time. We'll see how the numbers turn out in 2 months."

6 / 10
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49 Report
  • Anonymous
  • July 13, 2010

Sitagliptin for Type 2 Diabetes "I have been on Januvia 100 mg for about 1 year, 1 pill per day. My blood sugars ran from 124 to 138. The past 4 weeks my doctor increased it to 3 times a day because my blood sugar started to go up to 152-240. I wish I knew what happened. My diet is the same, and at first, I lost weight, and now am at a standstill. Maybe I should change. I have trouble sleeping and take something for that. Hope it will change soon."

5 / 10
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50 Report

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  • Aun...
  • January 16, 2018

Sitagliptin for Type 2 Diabetes "Keeps control of sugar, but having headaches, ear problem, insomnia, joint aches/pains, upper left side stomach sharp pains, gasping for breath... Not sure if from Januvia... How can I be sure w/o going to Dr.?"

7 / 10
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23 Report
  • SJH...
  • Taken for 1 to 2 years
  • March 15, 2023

For Type 2 Diabetes "The prescription was not really necessary as I had been informed that my HbA1c reading at my age was not a cause for concern. I took a dose of 25 mg daily. The side effects were dreadful - as follows: severe diarrhea for four days, which caused utter exhaustion and lack of sleep; complete loss of appetite, extreme lethargy, distortion of sense of taste, and it took almost three months for it to recover completely after I had ceased to take the tablet. There were also some minor effects, which I took to be more side effects."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.