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Wegovy and Vomiting: What Users Say (Page 2)

Reviews for Wegovy

Commonly mentioned side effects
  • Big...
  • Taken for less than 1 month
  • April 11, 2022

For Weight Loss (Obesity/Overweight) "Took my injection .25 mg Friday afternoon and had a very hard time eating dinner. By noon Saturday, I was violently ill with diarrhea, vomiting, and a fever. The symptoms subsided by Sunday, and I was left very achy and fatigued. On the upside, I guess I did go from 335 lbs to 318 lbs over the course of the weekend. This medication is not for the faint of heart. It is very depressing to see a full-course meal in front of you and only be able to eat a few bites. If you are serious about losing weight, this medication will get you there, but I wonder if it’ll work or if the side effects will at least subside with longer-term use. The nausea is horrible, but you do also have some beautiful dreams while taking it."

6 / 10
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  • Fay...
  • Taken for 6 months to 1 year
  • July 7, 2025

For Weight Loss (Obesity/Overweight) "I have been on Wegovy for 6 months. I am on the highest dosage now. It has not been a pleasant journey. I feel sick probably half the time. The worst side effect for me is constipation. I poop every 4th or 5th day. I get horrible cramps. I have only vomited 3 or 4 times. I’m waiting for the side effects to go away. I am going to stay on it for a year and re-evaluate if the side effects are worth it. I have never had chemotherapy, but I think this has similar side effects. I have lost 1 pound a week, so about 28 lbs."

5 / 10
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  • Deb...
  • Taken for less than 1 month
  • December 12, 2024

For Weight Loss (Obesity/Overweight) "The first four days have been really rough. I’ve experienced nausea, vomiting, severe heartburn, and stomach pain. I really want this to work, so I’ll continue. The doctors have had to prescribe nausea and vomiting medicine. It helps. I’m taking Alka-Seltzer for the heartburn. I’m really hoping the side effects will stop."

5 / 10
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Frequently asked questions

  • Sid...
  • Taken for less than 1 month
  • June 22, 2023

For Weight Loss (Obesity/Overweight) "Administered my first (and last) shot Tuesday, 6/20. Starting about 9 hours later that day, it's been vomiting and diarrhea nonstop. Can't keep ginger ale down, can't keep dry toast down. Can't keep plain crackers down. I have no clue where the stuff coming out of me is coming from. I wasn't a big eater prior to the injection, just with my age, I can't seem to drop pounds. With what I've been going through the last 48 hours (and still am), I will not be taking any further injections. Hope it works for all of you, but not for me."

5 / 10
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  • Jen...
  • Taken for 1 to 6 months
  • April 7, 2023

For Weight Loss (Obesity/Overweight) "I have been on Wegovy for 8 weeks now (0.5 mg dose). I had occasional nausea, but this week I had diarrhea, vomiting, gas, nausea, and stomach pain. Thank goodness I was able to work from home, otherwise, I would have had to call out. I thought I had the stomach flu, but now I wonder if it's the medication. I am supposed to move up to the 1 mg in two days, but I am scared to. I took Ozempic for two months, and the only side effect I had was horrible heartburn, but it was very difficult to get, so I had to switch. I am contemplating not taking this anymore. I can handle some nausea, but to be so sick you can't function is a whole other thing. And I have not lost any weight."

5 / 10
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  • CCM...
  • Taken for 1 to 6 months
  • April 28, 2022

For Weight Loss (Obesity/Overweight) "Started Wegovy at the end of March 2022 on 0.25, and it definitely worked at suppressing my appetite. I had slight nausea the first two days after injection, but not too bad. I just started the .5 dose on week 5, and I’ve gotten terribly sick. I was up all night with diarrhea and vomiting, similar to food poisoning. I don’t think I will continue after this experience. Very unfortunate because it does work if you can handle the side effects."

5 / 10
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  • Ano...
  • Taken for less than 1 month
  • June 18, 2025

For Weight Loss (Obesity/Overweight) "Lost 10 lbs in 3.5 weeks, but the side effects mean I will be stopping. Diarrhea, vomiting, stomach cramps, headaches, bloating. Felt ill most of the time. Working and traveling problematic due to having to be close to a toilet!"

4 / 10
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More FAQ

  • All...
  • Taken for 1 to 6 months
  • March 15, 2023

For Weight Loss (Obesity/Overweight) "I took 4 shots of .25 Wegovy. The first shot had no side effects and no problems. The second shot was a little different. Mild upset stomach starting about 24 hours afterward with some stomach pain. This subsided within the third day. My appetite was suppressed, felt fuller for longer. In the third shot, I had no appetite with stomach pain that lasted two days, and also felt as if I were going to pass out. I drank orange juice and ate saltine crackers with peanut butter, which helped. The last .25 shot of Wegovy… I had lost 12 pounds by this shot. But within a day, I was projectile vomiting, upset stomach, extreme pain in my abdomen, chills, and dizziness. I was taken to the emergency room. I was diagnosed with colitis that had gone to sepsis. The doctor explained a side effect from Wegovy may cause gastrointestinal problems. Wegovy attacked my colon and in turn, sepsis formed. I will not continue this shot. So many side effects go with it. It does curve your appetite, but I would be very cautious."

4 / 10
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  • Not...
  • Taken for 1 to 6 months
  • July 24, 2025

For Weight Loss (Obesity/Overweight) "I started this medication about 4 months ago and have lost almost 40 lbs on it. That was great until my last dosage increase that sent me to the hospital for almost a week with little to no motility in my entire gut and pain like I have never experienced. I couldn’t keep any food down or liquids and had to be on an IV for five days straight. This medication started out working great for me with the occasional vomiting and upset stomach. I think this medication truthfully should be taken off the market for how much damage it can create, but like I said it is not for everyone, and is certainly not for me. Best advice I can give is to listen to your body!!"

3 / 10
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  • Joe...
  • Taken for 1 to 6 months
  • May 30, 2023

For Weight Loss (Obesity/Overweight) "Side effects of nausea and vomiting. 0.5 mg doses are on serious back order, so went to 1 mg dose. No longer taking due to side effects."

3 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • May 24, 2023

For Weight Loss (Obesity/Overweight) "Easy to administer, but during the first few weeks, had zero weight loss. Dose was increased. Woke in the middle of the night after the last dose with severe heartburn. Vomited every four hours for two days. Missed a day of work. Not able to keep anything down, including water. Put on anti-nausea medication. Have to sleep in a sitting position and take antacids and prescription meds to control heartburn enough to sleep. Cannot wait for the medication to get out of my system so I can function without vomiting or constant heartburn."

3 / 10
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  • Dee...
  • Taken for 1 to 6 months
  • April 10, 2023

For Weight Loss (Obesity/Overweight) "I wish I did more research before starting this. I started on Saxenda and worked up to 3.0 mg, the max dose. I had a few bouts of severe diarrhea and vomiting. I lost a total of 15 pounds and then started getting ravenous. Then I got switched to Wegovy 2.0 mg and then moved up to 2.4 mg. I only had a couple of incidents of terrible nausea, usually when I ate greasy, heavy, or fried foods. But generally, I feel like crap every day. Once on the Wegovy, the weight literally fell off. Mostly because I just didn't think about eating anything, or my appetite would be satisfied with a very small portion of food. The biggest side effect is skin irritation; like a constant sunburn. Clothes touching my skin bother me. Or riding in a car and bouncing. It became intolerable. And chills make my skin ache. I easily surpassed my goal weight and now trying to decide if I want to quit it altogether or reduce the dosage and hope the skin irritation goes away."

3 / 10
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  • Mic...
  • Taken for less than 1 month
  • November 11, 2022

For Weight Loss (Obesity/Overweight) "Horrible! Spent 24 hours in the ER with severe nausea and vomiting! Needless to say, I have 3 doses left if anyone needs!"

3 / 10
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  • Car...
  • Taken for less than 1 month
  • July 25, 2022

For Weight Loss (Obesity/Overweight) "I am on my second week. First week (day after shot) I got severe nausea and dry heaving. I was so exhausted and zero energy. My depression got way worse. Second week the same. I don’t think I will continue, but I signed a contract, and I was told I can cancel at any time, but it looks like this is going to be a problem. This has been a wake-up call, and the nausea has taught me a lesson to never eat bad foods again and really focus on portion control. The side effects aren’t worth any weight loss in my opinion!"

3 / 10
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  • Kar...
  • Taken for 1 to 6 months
  • February 2, 2022

For Weight Loss (Obesity/Overweight) "It works amazingly well, but the actual and physical cost was too much for me to continue. Been on it since August, and I've lost 40 pounds. That's really easy to do when you're starving due to constant nausea and vomiting. Though I'm terrified of gaining the weight back, as others described, I had to stop taking it as I was so sick every day and exhausted. I'm fighting it, but my appetite has already returned with a vengeance. That's not surprising, considering I've been malnourished for months."

3 / 10
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  • Ang...
  • Taken for 1 to 6 months
  • July 22, 2024

For Weight Loss (Obesity/Overweight) "I started on 0.25 Wegovy. The injections are painless and easy to administer. For the 4 weeks, I took this dose, I felt fine with little side effects. I lost 3 lbs. I then moved onto 0.5 dose. I took the dose on a Friday and woke in the middle of the night with terrible sudden reflux and vomiting. This happened for 3 nights. I took my next 0.5 dose the following Friday and the same happened, along with dizziness, constant nausea, and very low mood. I have decided not to take the last 2 injections I have left as I just feel so poorly."

2 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • June 21, 2023

For Weight Loss (Obesity/Overweight) "I have lost 37 lbs in 3.5 months, but should be more due to the horrific side effects. Burping, belching, vomiting, diarrhea, chest pain, nausea, blurry vision, basically every side effect imaginable. I never had side effects from any medications before. I continued to increase the dose up to 1.7 mg and hope for the best with no success. I have three more weeks of misery, but due to the cost of $586, I refuse to trash this medication."

2 / 10
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  • Hel...
  • March 17, 2022

For Weight Loss (Obesity/Overweight) "I can’t figure out how to live with this drug without feeling sick or vomiting. Zofran helps, as does not eating. Then I try to eat what seems like a small amount of food, and I’m sick. This sucks, but my last resort!"

2 / 10
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  • Sks...
  • Taken for less than 1 month
  • May 25, 2023

For Weight Loss (Obesity/Overweight) "I never leave reviews and rarely have side effects from medication. However, after one injection on the lowest dose, I am so beyond sick. Two days after my injection, I got a migraine followed by extreme vomiting for 4 days, chills, nausea, and a trip to the ER. This medication made me so unbelievably sick, it is like I've been poisoned. I have missed 4 days of work and am so weak. Living on Pedialyte and numerous nausea medications. Please be so careful. I was so hopeful and had no idea this would happen to me."

1 / 10
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  • 188...
  • Taken for 1 to 6 months
  • May 17, 2023

For Weight Loss (Obesity/Overweight) "Started Wegovy 3 months ago using the gradual phase-up method. From 0.25 mg dose for 4 weeks to 0.50 mg dose for 4 weeks, then 1.0 mg dose for 4 weeks. During the initial phase, I experienced mild nausea and some stomach irritation. With each increase, the symptoms got worse until finally, at the full 1.0 mg dose, I was so sick I thought I had stomach flu for 2 weeks continuously. The belching was horrible. The nausea caused uncontrollable vomiting, and I had frequent diarrhea. After 3 months, I lost 12 pounds and felt horrible every day. I've now reduced the dose to 0.5 mg but still suffer from nausea and stomach upset. I might cut back again, but I'm thinking I will quit. The way I feel all the time is horrible! I'm thinking I lost weight because of all the vomiting. Not recommended."

1 / 10
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  • Jac...
  • Taken for less than 1 month
  • March 12, 2023

For Weight Loss (Obesity/Overweight) "Worst medication ever. On the lowest dose, I became deathly ill. I couldn't stop vomiting for a week. I could not walk because of extreme dizziness, and I could barely see from blurry vision. It also gave me the worst migraine of my life and suicidal thoughts and depression. I only lost weight because I could not eat at all and couldn't keep liquids down, so I was severely dehydrated. The side effects and long-term effects are so severe that the minor weight loss you would have from this medication is not worth it."

1 / 10
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141 Report
  • Jan...
  • Taken for less than 1 month
  • January 9, 2023

For Weight Loss (Obesity/Overweight) "Took my first 0.25 mg Wegovy dose yesterday. I felt nauseous about an hour later, but within 2 hours, I started vomiting. For the next 16 hours, I dry heaved throughout the day and night. I couldn't even keep water down. It hasn’t been a full 24 hours yet since I took the shot and feel horrible, hoping that these side effects will stop soon. There is no way I’m taking another shot next week."

1 / 10
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  • Jan...
  • Taken for less than 1 month
  • January 9, 2023

For Weight Loss (Obesity/Overweight) "Took my first 0.25 mg Wegovy dose yesterday. I felt nauseous about an hour later, but within 2 hours, I started vomiting. For the next 16 hours, I dry heaved throughout the day and night. I couldn't even keep water down. It hasn’t been a full 24 hours yet since I took the shot and feel horrible, hoping that these side effects will stop soon. There is no way I’m taking another shot next week."

1 / 10
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  • MM...
  • Taken for 1 to 6 months
  • December 22, 2022

For Weight Loss (Obesity/Overweight) "Wegovy has agonizing side effects. I had to quit after 2 months. Constant, uncontrollable vomiting, I vomited at work and while driving (which was horrific and dangerous). I essentially became bulimic and afraid to eat. I lost 20 pounds but put half of it back right away. Not worth the agony."

1 / 10
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56 Report
  • MM...
  • Taken for 1 to 6 months
  • December 22, 2022

For Weight Loss (Obesity/Overweight) "Wegovy has agonizing side effects. I had to quit after 2 months. Constant, uncontrollable vomiting, I vomited at work and while driving (which was horrific and dangerous). I essentially became bulimic and afraid to eat. I lost 20 pounds but put half of it back right away. Not worth the agony."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.