Wegovy and Constipation: What Users Say

• Wan...
• Taken for 1 to 6 months
• June 10, 2025

For Weight Loss (Obesity/Overweight) "I've been taking Wegovy since September (2024). I initially did not like the way it made me feel. I was experiencing constipation, headaches, and nausea. My next dose was 0.50, which the pharmacy was out of until this past April 2025. I was determined to see if I could withstand the side effects. My appetite was suppressed immediately. I experienced constipation, which I counteracted with stool softeners every day. I took Zofran for the nausea. I had started riding my stationary bike around the same time that I started Wegovy. On April 17th, 2025, I started walking 30 minutes a day. I am now at a 1.7 dose. Side effects are minimal. I noticed that if I am constipated, I would get nauseous. Stay away from heavy grease. I consume a protein shake every morning and try to eat meat as much as I can as I do not really have a taste for meat or I no longer like alcohol. I am happy that I tried it again. I am 6'1" and was 283. I am 266. I want to be 240. Yay!"

• Ano...
• Taken for 1 to 6 months
• June 8, 2025

For Weight Loss (Obesity/Overweight) "My experience with Wegovy has been typical. I’ve experienced diarrhea and constipation, but all of it was manageable and comes and goes. I'm a believer. The medication is working for me. 45 lbs down in six months without working out due to a knee and back injury. I would 100% recommend it to anyone."

• Ano...
• Taken for 1 to 2 years
• May 21, 2025

For Weight Loss (Obesity/Overweight) "Love this drug. I’ve lost 34 lbs with very little side effects. You do have to watch what you eat, some foods, especially fried foods, make you feel horrible. I’ve been on it for 1 year, which is good because I lost slowly, not all at once. The longer you keep the weight off. You do have to change your eating habits. In the beginning, I had a lot of heartburn, but I took OTC medicine, and eventually, I no longer had this problem. I’m not a big water drinker, so I’m trying to drink more water to help with constipation. You also have to limit your alcohol intake, so 1 glass of wine at dinner, and that’s it."

• Ano...
• Taken for 1 to 6 months
• April 9, 2025

For Weight Loss (Obesity/Overweight) "No adverse side effects. Just took 8th injection and last at 0.5 mg. Next week, dosage goes to 1 mg. Down 16 pounds in 7 weeks. I was already taking Metamucil every morning, so no constipation as some have reported, but I am having less bowel movements now. I imagine I would be constipated without it. Also take Nexium daily, so heartburn really hasn't been an issue more than it already was. Started at 6 ft and 251 pounds. Was 235 today. Goal is between 180 and 200."

• Bit...
• Taken for 6 months to 1 year
• March 23, 2025

For Weight Loss (Obesity/Overweight) "I started Wegovy in April 2024. I was 193 lbs at just between 5’1”-5’2.5. I had tried everything, but food noise and the fact that being so short, the calorie intake had to be so low to lose weight. Anyway, the first thing I noticed was a bit of nausea. That went away after a few days. I have had very minimal side effects. Sometimes a little nausea, constipation, or diarrhea. Nothing to really disrupt my life. For the first time in my life, I actually can tell when I am full. My IBS has been almost non-existent. I’m more awake. I have fewer sweet cravings. The food noise is still there, but my stomach is able to signal my brain that if I eat more, I will feel sick. I have lost to date 4/2024-3/2025, 63 lbs. I am just about to hit my normal weight goal. I knew how to lose the weight. I am someone who has a very difficult time shedding the weight with exercise and diet. I am super grateful for this opportunity to prove that a drug works so well."

• Aid...
• Taken for 6 months to 1 year
• March 7, 2025

For Weight Loss (Obesity/Overweight) "I’ve lost 30 lbs, and I’ve been on it for 7 months now. Currently on a maintenance dose. I experienced nausea, stomach pain, and constipation in the beginning, but no side effects now."

• Loc...
• Taken for 1 to 6 months
• February 17, 2025

For Weight Loss (Obesity/Overweight) "I have been on Wegovy for 10 weeks and have lost 40 pounds. I’m on a 0.25 dose and haven’t had to go up yet. Losing 2-3 pounds per week. The only side effect is constipation and dry mouth right after the injection and only lasts for 10 minutes. No complaints. Love the product! My insurance refuses to cover it. The doctor filed appeals and they still refused to approve. Will continue to use it for a few months to get to my goal weight."

• Hoo...
• Taken for 1 to 6 months
• February 14, 2025

For Cardiovascular Risk Reduction "I wanted to lose about 45 pounds and asked my cardiologist to prescribe Wegovy because I have cardiovascular disease. I'm on a Medicare Advantage insurance, and the med was approved. I have been on it for 2.5 months and am down 25 pounds. I haven't had any noticeable side effects except insane constipation. I already had issues with that, so I take a Linzess every morning, and that does the trick. I started noticing the curbed appetite the day after my first dose. It's not as intense now, but I have zero food noise, and I just can't eat like I used to. I have had migraines for 35+ years, and I haven't had one since starting Wegovy. I don't think it's my weight loss or improved eating habits, I think it's the medication. Before I became disabled, I was a size 4 and ate very healthy, but had 12+ migraine days per month. I inject my dose in the stomach each week and have never had any reaction to the injection. Overall, I am thrilled with Wegovy so far."

• Hoo...
• Taken for 1 to 6 months
• February 13, 2025

For Cardiovascular Risk Reduction "I wanted to lose about 45 pounds and asked my cardiologist to prescribe Wegovy because I have cardiovascular disease. I'm on a Medicare Advantage insurance, and the med was approved. I have been on it for 2.5 months and am down 25 pounds. I haven't had any noticeable side effects except insane constipation. I already had issues with that, so I take a Linzess every morning, and that does the trick. I started noticing the curbed appetite the day after my first dose. It's not as intense now, but I have zero food noise, and I just can't eat like I used to. I have had migraines for 35+ years, and I haven't had one since starting Wegovy. I don't think it's my weight loss or improved eating habits, I think it's the medication. Before I became disabled, I was a size 4 and ate very healthy, but had 12+ migraine days per month. I inject my dose in the stomach each week and have never had any reaction to the injection. Overall, I am thrilled with Wegovy so far."

• Zee...
• Taken for 1 to 2 years
• February 7, 2025

For Weight Loss (Obesity/Overweight) "70 pounds down and maintained for over a year now. Wegovy in conjunction with a high-protein, low-carb food plan does it right. I am convinced that the majority of negative outcomes are due to people just shooting the drug and making no changes to their diet. Stay off the sugar, keep your carb intake to vegetables and limited fruits only. Constipation avoided by adding a magnesium citrate supplement. (I use Calm)."

• Deb...
• Taken for 1 to 6 months
• January 25, 2025

For Weight Loss (Obesity/Overweight) "Amazing, but do suffer constipation. Lost two stone in eight weeks."

• CcA...
• Taken for 1 to 6 months
• December 21, 2024

For Weight Loss (Obesity/Overweight) "I am a 74-year-old male who weighed 250 when I started Wegovy. I am now a week into the 2.4 mg dosage and down to 224 lbs. My appetite has declined, and I no longer crave food. I have only one side effect, and that has been constipation. It started the day I began the medication and still continues. I am taking milk of magnesia, and it helps, but still not regular as I would like. I strongly recommend this drug."

• Dut...
• Taken for 1 to 6 months
• September 6, 2024

For Weight Loss (Obesity/Overweight) "I'm almost 2 meters long, and when I started, I was more than 157 kg. Within 11 weeks, I lost 22 kg. Almost every week, I lost 1.5 kg and more after the big water loss. For me, it's an addition to the bigger plan. Yes, I use Wegovy (now on 1 mg), but I also go to the gym 5 times a week and add some hour-long walks to my day. And yes, I also have a strict timeframe where I have my meals. And yes, they are mostly veggies and some yogurt with some granola for some fiber. I had some side effects like heartburn, burping, constipation, and I'm more tired than before. But I think that's a normal thing to process, especially when you make the transition. If you are seriously overweight, please consider this medicine as a small part of the bigger plan!"

• Weg...
• Taken for 1 to 2 years
• August 4, 2024

For Weight Loss (Obesity/Overweight) "I started on Wegovy on the 1st of June 2023. My weight was 109.7 kg. I started losing 1-2 kg per week at the start. Afterwards, the loss was more between 0.2-0.7 kg. I did not attend the gym or do exercises last year. I have started going to the gym now. My weight now in August 2024 is 73 kg. I have not experienced any side effects besides constipation. The plan is that after the end of August, I will start going down on the dosage and will fully stop taking it at the end of this year. My doctor told me that some of her other patients who have fully stopped it have managed to keep their weight by regularly exercising and by continuing to eat healthy, not overeating."

• Anonymous
• Taken for 1 to 6 months
• June 20, 2024

For Weight Loss (Obesity/Overweight) "I have been on Wegovy for 5 months. I have nothing but good things to say about it. I have lost almost 50 lbs and it has given me my life back. I was overweight and depressed for years after having my last child. The only side effect I have had is some occasional constipation. This medication is amazing!"

• big...
• Taken for 1 to 6 months
• May 27, 2024

For Weight Loss (Obesity/Overweight) "This is the first week at the 1mg dose, I lost 8 pounds last week. Before this, I was too scared to get on the scales, but I can feel I have lost significant weight. I have reduced appetite and cravings for sweet things that started almost immediately upon starting the drug. The only side effects I have had were, around week 3, constipation and trapped wind that caused waves of stomach pain for a few days. In the UK, you are supposed to be able to get this on the NHS if your BMI is over a certain level with associated health issues. However, no funding has been provided, so I am paying around £150-200 per month. This is offset by reduced food costs and alcohol costs that make it almost pay for itself."

• Tko...
• Taken for 1 to 6 months
• May 23, 2023

For Weight Loss (Obesity/Overweight) "I started approx. 3/29 and will begin my third step up to 1 mg this week. I have lost 23 lbs in 8 weeks. Very happy about that. My appetite is reduced. I can sometimes skip dinner because, after a light lunch and breakfast, I am not hungry. I have experienced fatigue, nausea, and constipation. However, if I eat something like an apple with peanut butter, that helps with the constipation. So far, these side effects are not bad enough for me to discontinue. I would like to feel better, but I am hoping it will improve. Fatigue is the worst for me because I also have another autoimmune disease that causes extreme tiredness. I am taking a multivitamin and see my doctor in a week, and I will discuss negative side effects. Right now, the benefits of losing weight are worth it."

• CFT...
• Taken for less than 1 month
• April 22, 2023

For Weight Loss (Obesity/Overweight) "In the fourth week on Wegovy, I lost 4.5 pounds. I have had constipation, but no nausea. It is helpful to drink a liter of water a day."

• Bac...
• Taken for 1 to 6 months
• March 9, 2023

For Weight Loss (Obesity/Overweight) "I started Wegovy 6 weeks ago at 0.25 mg for 4 weeks, and for the last 2 weeks at 1 mg. I started at 211 lbs and am now 197 lbs, so have lost 14 lbs and counting in 6 weeks. Not bad! Symptoms I've experienced include being slightly more tired than usual on the day of the injection, and some constipation at first but I use Miralax if there's an issue and it works fine for me. I haven't had any extreme nausea, but the injection definitely makes me less hungry and there are certain foods that I feel slightly queasy even considering eating-like high-fat foods-so I don't eat them. I eat a lot more fruits and vegetables and get full very quickly. I work out 4-5 days a week, my energy has been good and I feel like I'm getting back to my old self. I'd like to be about 135 lbs eventually. Wegovy has been a lifesaver. I'm 55 years old and had considerable cravings, especially at night. I'm happy to be free of them. I hope to make my new habits permanent."

• usm...
• Taken for 1 to 6 months
• November 29, 2022

For Weight Loss (Obesity/Overweight) "At this time, I’m on my 5th week of the maintenance dose. The only side effect I’ve had is occasional constipation, but as a 25-year medical professional, I know how to deal with it medically and in conjunction with my VA doctor and pharmacist. At times, I would get hypoglycemic, but again I knew how to combat that. At this dose, I find myself somewhat more fatigued but I can deal with that. Cat naps usually do the trick. I started at 393 and 6’3”. I’m 56 years old. I’m down to 349 since I started, which for me is great. I have critical low testosterone and can’t take testosterone due to my history of pulmonary embolisms. So, I don’t mind losing only 2 pounds a week. I can now walk so much better and farther. I’m 95% VA disability rated, and I’ll tell you, I feel and look so much better after starting to use Wegovy. The VA truly cares for us veterans no matter what you hear. Stay blessed and hang in there."

• Fin...
• Taken for 1 to 6 months
• July 5, 2022

For Weight Loss (Obesity/Overweight) "57-year-old on this for 3 1/2 weeks. I'd like to tell you how much I lost (was 4 pounds at 3 weeks), but I am so constipated for 4 days I cannot be sure what my real weight is (it could be 6 pounds now). Get a telemedicine provider to send you a vial of semaglutide (not the pre-loaded syringes) and use an insulin syringe to administer 1/2 the dose on one day with an ODT Zofran, then take the second half of the dose 24 hours later with another ODT Zofran. I administer in my outer thigh, like you would give insulin. The provider will tell you exactly how many 'units' to administer per week, just cut it in half, say Saturday and Sunday. Take a stool softener on Sunday, which I forgot to do this week! I have had zero gastrointestinal issues, no nausea, no vomiting. The Zofran may be causing some of the constipation, and I don't consider this a real issue, just a minor side effect with an easy fix. I am a Nurse Practitioner, so I have been watching everything for real side effects. I'll update."

• Tra...
• Taken for 1 to 6 months
• May 17, 2022

For Weight Loss (Obesity/Overweight) "Started Wegovy in Oct 2021. Down 30 lbs. It definitely curbs your appetite. The first couple of months were getting used to the change in signals from my body. Hunger pains felt different and not so intense. I did experience nausea - the doctor prescribed an anti-nausea medicine that helped greatly. Constipation was also an issue - again, the doctor suggested Milk of Magnesia, which helped with that. This has absolutely been a game changer for me. My struggles before were always being hungry, and I mean always. No matter how I curbed my diet (not a junk food/pop drinker at all) and exercised, I just could not lose weight. I had to stop it last month, not because I wanted to, but because my insurance company refuses to cover it. Even though I completely qualify for coverage, they said because the manufacturer could not keep it in stock, they won't cover it. Now I'm trying to maintain the meal portioning I was used to on Wegovy, but it's harder now that the hunger feelings are back."

• Hop...
• Taken for 1 to 6 months
• April 22, 2022

For Weight Loss (Obesity/Overweight) "I started on Ozempic 12 weeks ago in Jan 2022, which is the same as Wegovy in a lower dosage. I spent 4 weeks on the 0.25 dosage, losing 2 lbs. Moved up to the 0.5 dosage for 4 weeks, losing another 2 lbs, moved up to the 1 dosage for 4 weeks, and lost an additional 3 lbs. I just took my first dose of Wegovy at the 1.7 dosage, and wow can I tell a difference. I won’t lie, I have experienced a few side effects, such as constipation, some abdominal pain, nausea, headache, and diarrhea, but all have been mostly mild and very tolerable. Nothing that can’t be helped with eating a little less. The key to managing all of it is learning how to eat properly with the right portion sizes. Only eat until you are satisfied rather than full. For me, it is well worth dealing with mild side effects in order to achieve a healthy lifestyle!"

• CSB...
• Taken for 1 to 6 months
• April 1, 2022

For Weight Loss (Obesity/Overweight) "I am on my ninth dose, and I’m down thirty pounds. It curbs your appetite but also makes you nauseous. I’ve had constipation too. Stool softeners help. It works well and helps you lose weight."

• Sli...
• Taken for 1 to 6 months
• April 1, 2022

For Weight Loss (Obesity/Overweight) "So I am 5'4" and I found myself at the weight I was when I delivered my children, 145 pounds. For three years plus, I desperately tried to approach my goal weight of 125 pounds, dieting and feeling miserable for 3 years. I told my doctor I was dieting and exercising and could not budge the scale. At 60 years of age, the weight just doesn’t come off like when you are young. I’ve been on Wegovy for 6 weeks and have lost 12 pounds-a miracle! Now at 133 pounds, I’m staying the course to my goal. I will say the nausea is the worst side effect and comes in intermittent waves. I have Zofran (ondansetron) for when I can’t take the nausea. One of the best side effects for me has been totally eradicating my diarrhea. I have irritable bowel on the diarrhea spectrum, and luckily I did not get the diarrhea side effect but more the constipation, which has totally normalized my GI tract! I am so happy about this and assume this is due to slowing gastrointestinal motility."