Wegovy and Nausea: What Users Say (Page 4)
Reviews for Wegovy
- Gab...
- Taken for 1 to 6 months
- July 9, 2022
For Weight Loss (Obesity/Overweight) "Horrible, I had smelly sulfur burps and nausea at 1.7 mg. After the 2.4 mg limit, I became violently ill for two days. It was projectile from both ends. Very embarrassing. After that, just constant diarrhea for days. Throw it in the garbage."
- Mam...
- Taken for less than 1 month
- February 11, 2025
For Weight Loss (Obesity/Overweight) "I have been on Wegovy for 5 weeks, and I have already seen a decrease in my caloric intake (food record tracking) and a decrease in my appetite, which is helping with food intake. The only problematic side effects I have experienced are some indigestion and nausea in the 2nd - 3rd week of treatment, but this has resolved. I have just bumped up to .5 mL dosage with no issues. I am excited to be on this enhanced weight loss journey and look forward to positive results over the next months!"
Frequently asked questions
- 6 Wegovy side effects you need to be aware of
- Ozempic Mounjaro Wegovy & Zepbound: Weight Loss Compared
- Wegovy vs Ozempic: Which is Right for You?
- How long to see weight loss results with Wegovy?
- Wor...
- Taken for 1 to 6 months
- January 28, 2022
For Weight Loss (Obesity/Overweight) "First, I am disabled with Lyme disease and severe fibromyalgia. I gained 20 pounds because I couldn't move for 2 years. I went on Wegovy. I was okay with the side effects (no appetite, a little bit of nausea) until I got to the 1.7 dose. I tried for 6 weeks on that dose. I was the sickest after the dose day for the majority of the week. I could barely eat. I did lose weight: 18 pounds in 4 months. I did no exercise whatsoever. In fact, I'm mostly bedridden. But feeling that ill on top of my constant pain was too much for me. I went down to the 1 mg, and we will see if I can do that. I also take pain meds and a fibro drug (also causes nausea). I have a nausea med called Zofran. You might want to ask for this. The nausea is awful, but really not bad for me UNTIL I started the 1.7 dose. Just couldn't stay on that. Definitely takes off weight. At one point, I ate 800 calories in 4 combined days, it was that bad. You might want to titrate slowly."
- blh...
- Taken for less than 1 month
- May 31, 2024
For Weight Loss (Obesity/Overweight) "First dose 0.25mg, had slight stomach pain/discomfort. Later that same night, my appetite disappeared. Just seeing a fast-food commercial on TV made me feel nauseous. I thought if that's the worst of the side effects that affect me, then I'll be very happy with that. By the next day, stomach pain and nausea increased. By 4:00 am, BAM! Diarrhea, severe stomach pain, projectile vomiting, headache, chest pain, severe itching mainly on the palms of my hands and arms. I truly thought 'this must be what it feels like to be poisoned!' I was scared. It is now the next day and I feel fine. A little tired from lack of sleep from feeling so sick. I think I will do my second dose next week...but I'm quite nervous of a repeat of feeling like I was dying from the stomach pains and vomiting. Will I continue with this drug?...jury is still out! On the positive side, I've already lost 5 pounds; but of course, I can't & don't want to eat, too much nausea and vomiting."
- A H...
- Taken for 1 to 6 months
- May 14, 2024
For Weight Loss (Obesity/Overweight) "First few weeks, appetite started to fall away. Lost 6 lb, then the sickness started - nausea, bloating, and stomach pain. Certain foods make this worse, and the nausea is daily now. On week 6 and down 9 lb, going to keep going unless this gets worse. It's like being pregnant again!"
- WmB...
- Taken for less than 1 month
- June 13, 2023
For Weight Loss (Obesity/Overweight) "Wegovy hasn't resulted in any weight loss. At times, I'm nauseous, full, and constipated regularly. Also, the injection device failed to work, no clicks or moving yellow bar. The product failed to go in and leaked all over, thereby causing me to get no shot/dosage."
More FAQ
- Do Ozempic, Wegovy, Mounjaro & Zepbound cause hair loss?
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- Ano...
- Taken for 1 to 6 months
- April 7, 2025
For Weight Loss (Obesity/Overweight) "I started taking Wegovy 5 weeks ago. My starting weight was 74 kg, and I'm 67.9 kg. I've experienced great results, with limited side effects - mostly feeling nauseous, but it fades fairly quickly after the injection. I'll take it until I'm at my premenopausal weight, 62 kg. I highly recommend this drug for anyone 40 plus who's struggling to lose the belly fat. I'm currently on a 0.05 dose and don't feel the need to increase any further. My advice: start on a low dose, 0.25, and go from there. See a female doctor who specializes in women's health."
- Ano...
- Taken for 1 to 6 months
- April 8, 2025
For Weight Loss (Obesity/Overweight) "I am in week 10/injection 2 of 1 mg and taking Wegovy for weight loss. I started at 142 kg and am down to 132 kg, which is wonderful. My goal weight is 115 kg as I'm tall and solid build. The side effects, nausea, fatigue, headaches, and some bowel upsets tend to dissipate 3 days after the injection. Avoid big meals and heavy/fatty foods in particular to minimize side effects. Not enjoying food and the social side can be a bit tough, but the results far outweigh any downsides. You actually save money overall due to eating less. I intend to stay the course and highly recommend this life-changing experience."
- Sli...
- Taken for 1 to 6 months
- April 1, 2022
For Weight Loss (Obesity/Overweight) "So I am 5'4" and I found myself at the weight I was when I delivered my children, 145 pounds. For three years plus, I desperately tried to approach my goal weight of 125 pounds, dieting and feeling miserable for 3 years. I told my doctor I was dieting and exercising and could not budge the scale. At 60 years of age, the weight just doesn’t come off like when you are young. I’ve been on Wegovy for 6 weeks and have lost 12 pounds-a miracle! Now at 133 pounds, I’m staying the course to my goal. I will say the nausea is the worst side effect and comes in intermittent waves. I have Zofran (ondansetron) for when I can’t take the nausea. One of the best side effects for me has been totally eradicating my diarrhea. I have irritable bowel on the diarrhea spectrum, and luckily I did not get the diarrhea side effect but more the constipation, which has totally normalized my GI tract! I am so happy about this and assume this is due to slowing gastrointestinal motility."
- Dee...
- Taken for 1 to 6 months
- April 10, 2023
For Weight Loss (Obesity/Overweight) "I wish I did more research before starting this. I started on Saxenda and worked up to 3.0 mg, the max dose. I had a few bouts of severe diarrhea and vomiting. I lost a total of 15 pounds and then started getting ravenous. Then I got switched to Wegovy 2.0 mg and then moved up to 2.4 mg. I only had a couple of incidents of terrible nausea, usually when I ate greasy, heavy, or fried foods. But generally, I feel like crap every day. Once on the Wegovy, the weight literally fell off. Mostly because I just didn't think about eating anything, or my appetite would be satisfied with a very small portion of food. The biggest side effect is skin irritation; like a constant sunburn. Clothes touching my skin bother me. Or riding in a car and bouncing. It became intolerable. And chills make my skin ache. I easily surpassed my goal weight and now trying to decide if I want to quit it altogether or reduce the dosage and hope the skin irritation goes away."
- Hel...
- Taken for 1 to 6 months
- July 2, 2024
For Weight Loss (Obesity/Overweight) "Started with 0.25mg, very easy, full instructions, separate pens for each dose increment, so foolproof. The nausea started within a couple of hours of the first injection, over the first month the nausea was pretty constant all day but eased off after around 5 days so 2 days with minimum nausea, however within 1 hour of 0.5mg dose nausea was worse and no let up, was actually sick on 1 day and felt like I would be sick in the second week. After 2 weeks on 0.5mg decided I could not continue to feel unwell ongoing. Weight loss was minimal, less than 1lb per week with 'careful' eating choices although not fully dieting but think you have to be very determined to tolerate the nausea."
- Anonymous
- Taken for 1 to 6 months
- June 21, 2023
For Weight Loss (Obesity/Overweight) "I have lost 37 lbs in 3.5 months, but should be more due to the horrific side effects. Burping, belching, vomiting, diarrhea, chest pain, nausea, blurry vision, basically every side effect imaginable. I never had side effects from any medications before. I continued to increase the dose up to 1.7 mg and hope for the best with no success. I have three more weeks of misery, but due to the cost of $586, I refuse to trash this medication."
- Mic...
- Taken for 1 to 6 months
- June 3, 2023
For Weight Loss (Obesity/Overweight) "Started on 03/27/23 - 50/F, 5’6”, 238 lbs. On 0.25 mg, I lost 6 lbs, on 0.50 mg, I lost 10 lbs. Currently, I am on my third dosage of 1.0 mg and have lost 6 lbs. Works great, given, and is so easy to inject. This is just what I needed to boost my weight loss after gaining weight after MVA! Some SEs. No issues with 0.25 mg and slight nausea with the first dosage of 0.50 mg, but only lasted the first night. Also, after 6 months of no cycle, I got it when I started the first dosage of 0.50 mg and 1.0 mg with painful cramps, but only lasted two days. Obviously, eating less because I have a minimal desire to eat, but I am making better choices when eating (lots of protein). Also, walking more within my physical limitations. Very grateful for this medication and insurance coverage! So far, so great!!!"
- soc...
- Taken for 1 to 6 months
- May 22, 2023
For Weight Loss (Obesity/Overweight) "This is my 4th week on the injection. I don't have a scale yet, but my pants don't feel tight. I do feel nauseated, but have not thrown up. I do get full before I am finished with my plate. So far, I like it."
- San...
- Taken for 6 months to 1 year
- July 10, 2022
For Weight Loss (Obesity/Overweight) "I am about 6 months in, and at 2.4 per week, I have lost 17 lbs. It does work to curb your appetite, but I always feel sick. I have noticed I have developed severe migraines after week two, but kept going. I am currently on migraine medication, Ajovy, and it is not helping. Sometimes, it comes with blurred vision, which gets a bit better once it gets closer to taking it again. I have gone to the ER three times over 6 months with severe headaches, but nothing helps. It has really impacted my way of life, and I do feel like a worse wife and mother because I am always sick and have a constant headache that never, ever goes away. I gave it a go, but at this point, the cons outweigh the pros for me. I did stop Wegovy two weeks ago and noticed an improvement in my headaches and my menstrual cycle. Headaches basically gone, why didn't I stop sooner?"
- KB6...
- Taken for 1 to 6 months
- January 28, 2022
For Weight Loss (Obesity/Overweight) "Have been on the drug for four months and have lost 14 lbs. Now on 1.7 mg dose and have had intense nausea off and on for the last 3 weeks. Prior to this, on lower doses, nausea was milder, but heartburn and reflux were worse. If this kind of nausea persists, I don’t think I can stay on the drug much longer. It’s just too brutal to be so nauseated and tired for so much of the day."
- Tin...
- Taken for 1 to 6 months
- March 8, 2023
For Weight Loss (Obesity/Overweight) "Been on Wegovy 0.25 mg for 6 weeks now and have lost 15 pounds. I have had side effects of nausea after injection for about 24 hours and constipation, which is resolved with laxatives. Wegovy curbs your appetite and has changed the taste of certain foods for me. I am increasing the dosage to 0.50 mg to see if weight loss is quicker."
- Tam...
- Taken for 1 to 6 months
- November 27, 2024
For Weight Loss (Obesity/Overweight) "Experienced nausea and acid reflux with first four doses. The second box, the first pen did not work properly, the needle did not go all the way in. The medicine caused a bubble under the skin, was burning and hurting more than just the original needle stick. Called the drug company, they said because I did not watch the yellow tab, I would not be reimbursed. Not to mention that the medicine had no place to go until I pulled it out, and it sprayed all over my hand. The drug company is not good about standing behind their faulty product. If you have a problem, make sure to say you were watching the yellow bar, and you may have a chance at getting it replaced. Not good customer service."
- Big...
- Taken for less than 1 month
- April 11, 2022
For Weight Loss (Obesity/Overweight) "Took my injection .25 mg Friday afternoon and had a very hard time eating dinner. By noon Saturday, I was violently ill with diarrhea, vomiting, and a fever. The symptoms subsided by Sunday, and I was left very achy and fatigued. On the upside, I guess I did go from 335 lbs to 318 lbs over the course of the weekend. This medication is not for the faint of heart. It is very depressing to see a full-course meal in front of you and only be able to eat a few bites. If you are serious about losing weight, this medication will get you there, but I wonder if it’ll work or if the side effects will at least subside with longer-term use. The nausea is horrible, but you do also have some beautiful dreams while taking it."
- Sar...
- Taken for less than 1 month
- April 10, 2022
For Weight Loss (Obesity/Overweight) "Made me terribly sick. Took only 0.25 dosage one time, had terrible diarrhea, extreme exhaustion, and some nausea. Definitely not taking the second dose. Not worth the pain. Did not lose any weight either. It stops you from eating because it makes you feel so bad if you do. I also think this drug is meant for someone who doesn’t live an active lifestyle. I work out all the time, I eat healthy, and really just wanted to drop 15 lbs. This drug was very disappointing."
- Fay...
- Taken for 6 months to 1 year
- May 15, 2025
For Weight Loss (Obesity/Overweight) "I have been experiencing nausea at least once a week. I’m finding it hard to eat as I have been turned off most foods. I used to love chocolate, but I can only manage to eat the odd piece. I used to like sweet things, but now sweets are far too sweet!"
- Car...
- Taken for less than 1 month
- July 25, 2022
For Weight Loss (Obesity/Overweight) "I am on my second week. First week (day after shot) I got severe nausea and dry heaving. I was so exhausted and zero energy. My depression got way worse. Second week the same. I don’t think I will continue, but I signed a contract, and I was told I can cancel at any time, but it looks like this is going to be a problem. This has been a wake-up call, and the nausea has taught me a lesson to never eat bad foods again and really focus on portion control. The side effects aren’t worth any weight loss in my opinion!"
- lol...
- Taken for 1 to 6 months
- May 13, 2025
For Cardiovascular Risk Reduction "I have lost 20 lbs, but the nausea and constipation never went away. It did help my BP, but if you want to see the effects on your face, go outside with a mirror, and you will see the effects it has on your skin. I have always had good skin, but now I have crow's feet and wrinkles around my mouth that are much deeper than I didn’t have before. What people called Ozempic face is the same thing you get with Wegovy. The fast weight loss will leave you with loose skin also if you are older."
- Roe...
- Taken for 1 to 6 months
- April 16, 2024
For Weight Loss (Obesity/Overweight) "I have been on Wegovy for 2 months. No weight loss. Still hungry. I have been nauseated at times, and it’s been depressing because I haven’t lost any weight. Need to increase my water intake, though, and I’m about to start a higher dosage, so I’ll definitely keep you all posted."
See also:
More about Wegovy (semaglutide)
- Wegovy consumer information
- Check interactions
- Compare alternatives
- Reviews (516)
- Drug images
- Latest FDA alerts (4)
- Side effects
- Dosage information
- During pregnancy
- Support group
- FDA approval history
- Drug class: GLP-1 Agonists (Incretin Mimetics)
- Breastfeeding
For Weight Loss (Obesity/Overweight) "I am 58, have IBS-D, no gallbladder, GERD, and am 60 lbs overweight. This is my second attempt at taking Wegovy. The first attempt was disastrous! I didn't make it through the first week before I was hit with diarrhea, nausea, acid reflux, dizziness, cramps, and had headaches. I missed four days of work and went to ER twice. The doctor did tell me to stop taking this, but I honestly did not think it was the Wegovy (I had not done any research on side effects). Once I got back to my normal state of digestive issues, I became proactive. I started back on Wegovy (.25 lowest dose) 6 weeks ago, but now I take a dose of Pepto-Bismol daily (twice a day the day of and day after the shot) and I take an OTC daily antacid. I still get mild side effects (nausea, headache, and fatigue) the day after the shot or if I overeat. I have not lost any weight at this dose so I am going up to the .5 dose next week. As others have said - everyone will react to this med differently."