Semaglutide and Headaches: What Users Say (Page 5)
Brand names: Ozempic, Rybelsus, Wegovy
Reviews for Semaglutide
- Iri...
- Taken for 1 to 6 months
- October 10, 2019
Semaglutide for Type 2 Diabetes "Started Ozempic a month ago. I had a bit of diarrhea with the first two injections. Now it is just the headache and fatigue feeling. I haven't noticed any changes in appetite. I had been losing weight for three months prior to starting Ozempic. I was down 42 pounds, since starting, I'm up six pounds. I haven't noticed any difference in my blood sugar numbers. Not impressed so far."
- And...
- Taken for less than 1 month
- October 18, 2019
Semaglutide for Type 2 Diabetes "I started Ozempic injections 3 weeks ago (by the way, I live in the UK). I also take Metformin and Foxigra. I had a slight headache and nausea, which I seem to get a few days after the injection. I don't find I get any appetite decrease that much, and I've put on weight this week. But sticking with it, so we shall see."
Frequently asked questions
- Ozempic Side Effects to Watch For
- Wegovy vs Ozempic: Which is Right for You?
- Tirzepatide vs semaglutide: How do they compare?
- Which GLP-1 drug is best for weight loss?
- dee...
- Taken for less than 1 month
- April 7, 2023
Semaglutide for Weight Loss (Obesity/Overweight) "Just completing week one at the low dose. I did the research after being given the prescription and expected there would be side effects, so planned for it. I bought antacids and Gravol and waited. The injection site is the thigh, and I got a small bruise. I did not feel the injection at all. I had minor side effects on day one, of a headache and feeling queasy. Since then, only some belching if I overeat. It is like my brain suddenly recognizes I have eaten."
- Wri...
- Taken for 1 to 6 months
- August 21, 2021
Semaglutide for Type 2 Diabetes "I have been taking Ozempic for 10 weeks for both weight loss, which I have struggled with for years, and diabetes. I experienced nausea, constipation, slight dizziness, and headaches, but nothing that I couldn't manage, and only for 1 or 2 weeks of each increased dose. Went from 0.25 to 0.5, and now I'm on week 2 of the highest dose, 1.0, and currently have no side effects. I have also lost 19 lb so far, the doctor advised a 1200-calorie diet, and I couldn't be happier. My blood levels have come down from high 7's to 6.4, and the doctor is considering taking me off my usual diabetic medication, Empagliflozin. Some folks are saying, 'don't take it,' but just because their body didn't take to it doesn't mean you won't! And you could be missing out on what I would say is a game-changing medicine. I would say give it a go. And I wouldn't give up now for anything. My health has significantly improved. (Free to diabetics in the UK)."
- Car...
- Taken for 1 to 6 months
- March 2, 2025
Semaglutide for Type 2 Diabetes "1st week stomach discomfort (not too bad). 2nd week flatulence (sudden, uncontrollable, embarrassing). 3rd week sore throat, lots of phlegm, hard to swallow! 4th week, no appetite at all! Sudden diarrhea, no control, running out of me like water! I’m experiencing back pain in between my shoulders! Headache! 8-9 in pain! 10 excruciating!"
- lil...
- Taken for 1 to 6 months
- January 9, 2020
Semaglutide for Type 2 Diabetes "Thank you all for your comments. I didn't realize the headaches were from the Ozempic. I have not suffered from the runs, but did get the reflux. I have had it before and already take meds for it. It is a relief to see my symptoms are, while not great, fairly normal. I am on week 4 at .25 and will go up to .5 in two more weeks."
More FAQ
- Why am I not losing weight on Ozempic?
- Does Ozempic cause muscle loss and how to prevent it?
- How much does semaglutide cost?
- How does semaglutide work for weight loss?
- Rif...
- Taken for less than 1 month
- February 11, 2025
Semaglutide for Type 2 Diabetes "When I heard about Ozempic, the insulin is being used as weight loss, then I thought it wouldn't work for me as a type 2 patient. With another insulin, I was tired and frustrated. So I asked the specialist to try Ozempic. She agreed. I have just started this 5 days ago, so far, I have had headache, vomiting, but no stomach upset. With 2.5 mil dosage and regular medication, it's working. Hopefully, it will help me in the long run. Thank you."
- Jea...
- Taken for less than 1 month
- June 7, 2023
Semaglutide for Type 2 Diabetes "Nausea, bad acid reflux at night, nightmares, headache every morning, constipation, chills, fatigue. Just started a week ago. Blood sugar levels in the 80s and 90s. Have lost no weight. Zero appetite. Blurry vision."
- hal...
- Taken for less than 1 month
- June 4, 2023
Semaglutide for Type 2 Diabetes "The major side effects are all I got with this med, which includes upset stomach, heartburn, burping, gas, bloating, nausea, vomiting, stomach pain, loss of appetite, stomach flu symptoms, headache, dizziness, and tiredness."
- Anonymous
- Taken for 1 to 6 months
- May 23, 2023
Semaglutide for Type 2 Diabetes "Twelve hours after I was injected with 1 mg Ozempic, I had severe headaches and vomited for almost four days. No matter what I eat, I feel dizzy and have a bad taste in my mouth. I ate soft and nonfat foods, but still, the vomiting continued. I never had constipation or diarrhea."
- Lyn...
- Taken for less than 1 month
- May 10, 2023
Semaglutide for Weight Loss (Obesity/Overweight) "I haven't noticed much weight loss with this medication. I have experienced extreme nausea to almost vomiting. I have also suffered from daily headaches from this medication. I have also noticed my blood pressure fluctuates higher than my normal high. I am only on the 1.0 mg dosage right now, and my doctor will increase it next week. I do have to say the pens are very easy to use, and the needle injections don't hurt."
- Wen...
- Taken for 1 to 6 months
- March 8, 2022
Semaglutide for Type 2 Diabetes "I have been on Ozempic at the lowest dose for 4 weeks. The first week was brutal, with stomach pain, nausea, vomiting, and headache, however, I injected the second week in my thigh and the side effects waned. It appears to be lowering and leveling my A1C. I'm nervous about increasing my dose next week. I can manage a week of discomfort as long as it is short-term. My body does seem to be getting used to it. I'm willing to work with it as long-term benefits for me outweigh the short-term discomfort. I may change my mind as time goes on, as these horror stories have me concerned. So strange that there is such a wide range of patient experiences...both good and bad."
- Huc...
- Taken for 1 to 6 months
- March 13, 2022
Semaglutide for Weight Loss (Obesity/Overweight) "OK, I gained over 40 pounds due to injuries, then COVID. I started at 257 lbs, today I'm at 237, and I'm on the second month of 0.5 ml injection. The side effects are a pure nightmare! But as I got to 0.5 ml, they taper off. I carry Tylenol for the headaches, and my gastroenterologist prescribed Carafate for indigestion, Pepto-Bismol works too. If you can hang in there for the first 2 months, you'll be good."
- Fro...
- Taken for less than 1 month
- December 13, 2021
Semaglutide for Type 2 Diabetes "My doctor prescribed it as a miracle drug, bought a 0.25 mg kit. My doctor gave me instructions, but I found better instructions on YouTube, so the next day I was ready with all that info. I cooked a light soup, no carbs, no fat, etc. I drank water, washed my hands, cleaned my belly, and did the shot. All was okay. After a few hours, abdominal pain, my eyes started to itch, then blurry vision. I went crazy, wondering what happened to me, went to bed, then the nausea came with a headache. The next days I was sick and did not go away, so I phoned my doctor. She said it's all in my mind and I will get used to it. Now I am afraid of the second injection, is it worth it? Why pay for an expensive drug to get sick? The only positive was that it lowered my morning blood sugar from 100-110 to 88. I take 1000 mg of metformin twice a day. For others, do not use it for the first time and go to work, it's good to do it when you do not have work the next day."
- Ann...
- Taken for 1 to 6 months
- October 22, 2021
Semaglutide for Type 2 Diabetes "This is a horrible drug. I thought I was dying, my stomach hurt so bad. I'd be in a ball on the couch. I had headaches, constipation, vomiting, could not eat, lost 20 lbs so fast, my skin sagged. Do not take this medication."
- Anonymous
- Taken for 1 to 6 months
- September 18, 2021
Semaglutide for Type 2 Diabetes "My doctor started me on 0.25 mg about 4 weeks ago for my diabetes. My first week, there were no symptoms, my second week, I started feeling nauseous all the time, dizzy, headache. I’m now sick every day. I try to eat, I get very hungry but am not able to eat more than a few bites without wanting or needing to vomit. I shake all the time from my sugar levels dropping so low. It seems like I’m always hypoglycemic but not able to stop it! Some days I don’t even want to get out of bed, I’m so sick! THIS IS THE WORST MEDICINE I’VE EVER TAKEN!! It seems to be good for some people, but certainly not for me."
- Jul...
- Taken for 1 to 6 months
- March 10, 2022
Semaglutide for Type 2 Diabetes "Newly diagnosed with type 2, started with .25 for 5 weeks. Lots of waves of nausea, headaches, and overall discomfort. Week 5 did get better, the side effects lasted just a day or two after injection. .5 has been a 2-week nightmare. Extremely painful headaches, nausea, and now constipation. I am hoping there's a different med I can try that isn't so hard."
- Jul...
- Taken for 1 to 6 months
- March 10, 2022
Semaglutide for Type 2 Diabetes "Newly diagnosed with type 2, started with .25 for 5 weeks. Lots of waves of nausea, headaches, and overall discomfort. Week 5 did get better, the side effects lasted just a day or two after injection. .5 has been a 2-week nightmare. Extremely painful headaches, nausea, and now constipation. I am hoping there's a different med I can try that isn't so hard."
- Haw...
- Taken for less than 1 month
- May 11, 2023
For Weight Loss (Obesity/Overweight) "Three days ago, I took my third injection of 0.25 mg. I am so, so sick. I have been sick with nausea and burping since I took the first injection, but this week is the worst. Nausea, vomiting, dizziness, headaches. Today was so intensely bad I almost went to the ER. I’m trying to keep going as I desperately want to lose weight. I’m down 10 lbs in 17 days, but I’m so sick I can’t even eat healthy foods. I don’t know if I’ll be able to do the next injection, this has been so horrible. My doctor also prescribed Zofran for the nausea, but it’s not helping. Will the side effects ever stop, or should I just give up?"
- Han...
- Taken for 1 to 6 months
- June 18, 2023
Semaglutide for Weight Loss (Obesity/Overweight) "I need to lose weight. I have lost 25 pounds in three months with this medication. Worst side effects I have experienced are occasional headache, constant tiredness, and I am cold in the afternoons. I’m on the 1.7 mg starting today."
- Bre...
- Taken for 1 to 6 months
- June 14, 2023
Semaglutide for Weight Loss (Obesity/Overweight) "I began using Wegovy injectable semaglutide exactly 8 weeks ago today and have had very few symptoms, until the 7 1/2 week mark. At first, my nose ran continually, but that was somewhat manageable with Robitussin (recommended by the pharmacist) for the cough it caused. At dinnertime, at the 7 1/2 week mark, fatigue hit very hard. We were on a trip, and I could barely walk to get back to the hotel and fall in bed. This continued for 48 hours with no desire for food or drink, except ice water. I slept for 5 or 6 hours and awoke with a headache, which lasted the rest of the night. Strange because I do not get headaches. Thankfully, we were headed home at that point, and I slept in the car most of the day for two days. I am much improved and can function somewhat, but not back to normal yet. I am due to double my dose today, but the medication not available for a while due to high demand. Easy to use and have lost 10 lbs in 8 weeks."
- not...
- Taken for 1 to 6 months
- May 3, 2023
Semaglutide for Type 2 Diabetes "I unfortunately had a very severe reaction to Ozempic. I usually do suffer side effects from most medications, but thought I would give it a try. The first two weeks were headache, general stomach ache, and constipation lasting 2 days after each injection. Weeks 3 and 4 got worse. Stronger reactions, lasting longer. Week 5, I started the double dose, and I was pretty ill for 2 days. Week 6 and 7 was rough, but I thought I could ride it out. Week 8 had me in emergency twice for diarrhea, vomiting, headache, and major dehydration. I was unable to eat or drink anything. I had to get rehydrated and be given anti-nausea meds on both occasions. I guess my body slowed the release of food so much I had a massive buildup to the point even a sip of water made me extremely nauseous. Ozempic is not for me."
- lee...
- Taken for less than 1 month
- June 15, 2023
Semaglutide for Weight Loss (Obesity/Overweight) "This is my second week on Wegovy. During the first week, I felt fine, but this week, I am experiencing extreme fatigue, tachycardia, headache, and craving sweets. I find myself not eating anything other than meat and no sides. I think I might be done with it. I don't like feeling like this. It's just the second week, and I can't imagine what the third week would feel like."
- KEW...
- Taken for 1 to 6 months
- December 29, 2021
Semaglutide for Type 2 Diabetes "I was started on a 30-day trial of Ozempic at the same time I was started on Metformin. Everything went okay for the first couple of weeks, although I did notice a slight headache the day I took my dose of Ozempic. Then, right at the time I stepped up my dose per the trial instructions, I started getting violently ill. They had me stop both medications and start one back at a time, and it was determined I can't tolerate Metformin. After trying Jardiance and only getting small results, they started me back on Ozempic. I was sick within 2 days of my first dose. My stomach would not digest any vegetables, which sort of defeats the purpose of taking it for blood sugar management when all you can tolerate are simple carbs. After the 2nd dose, I decided I was spending too much time trying not to be violently ill after eating and asked to be taken off the medication. Thankfully, since I was only 2 weeks in, I was able to notice a decrease in symptoms within a week of stopping. Not for me."
See also:
More about semaglutide
- semaglutide consumer information
- Check interactions
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- Reviews (2,724)
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- Side effects
- Dosage information
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- Support group
- Drug class: GLP-1 Agonists (Incretin Mimetics)
- Breastfeeding
Semaglutide for Cardiovascular Risk Reduction "I did not like the side effects that I experienced while taking Ozempic. The first day I was on Ozempic, I had severe vomiting. Although I did not continue to vomit, I did feel nauseated and not well the 4 months while on Ozempic. I also started experiencing severe headaches, and my sinuses became very dry and hurt. I then lost my sense of taste and smell. I stopped taking it right away. It has been more than two years since I last took Ozempic and still cannot taste or smell. I would not recommend this drug to anyone."