Ozempic and Nausea: What Users Say

• Oze...
• Taken for less than 1 month
• May 14, 2023

For Weight Loss (Obesity/Overweight) "With just one 0.25 mg dose, I became very ill. Relentless nausea, vomiting, and explosive diarrhea, as well as unbearable stomach cramps. Needed to go to the ER for fluids and to check for pancreatitis. It’s now been 9 days since my first dose, and I still have relentless diarrhea, nausea, and disabling fatigue. I don’t want to eat. I didn’t want to take it in the first place but was ambushed by my kidney doctor. She told me that using Ozempic was a no-brainer and that I would just have a bit of nausea. If you have any gastrointestinal symptoms when taking any medicine, I would think three times about it before using it. I have read it can take up to a month for it to be flushed out of your body, but I am hoping and praying that these horrible side effects stop real soon."

• KCF...
• Taken for 1 to 6 months
• March 25, 2025

For Chronic Kidney Disease "I have been on Ozempic for the past 1 1/2 months. Gradually increased from 0.25 mg for 4 weeks, then 0.5 mg since then. After reading other reviews, the best tip I found was injecting into my thigh instead of the abdomen. Mild nausea, backache, and constipation the first 2 weeks, and nothing now but the feeling of fullness soon after eating, about 75% as much as usual. I have less interest in sugary or fried foods and have lost 12 pounds, about 2 pounds a week. At 74, my Type 2 diabetes is diet-controlled with good A1C's, so my primary use is for weight loss and preserving kidney functioning. The tiny 27 gauge needle is painless, just wish I had discovered Ozempic sooner!"

• Los...
• November 10, 2019

For Type 2 Diabetes "I am a 70-year-old type 2 diabetic and was taking one Metformin 500 ER for the past year or so. My A1C was 11, and it dropped to 5.6 by changing my diet and taking the Metformin. My doctor wanted me to try Ozempic to help me lose weight and possibly eliminate the Metformin. The side effects were terrible right from the start. Nausea and diarrhea, no vomiting, just nausea. I started at 0.25 and am now up to 1.0. My appetite is gone completely. I have no desire to eat at all. When I do eat, I get full almost immediately. I have gone from 228 lb down to 202 lb in the six weeks I have been taking Ozempic. I'm thrilled with the weight loss, and the nausea and diarrhea have improved. However, I have almost stopped peeing. I go in the morning, then go all day into the evening without going. Since I suffer from incontinence, it's good, but I am worried that it might be damaging my kidneys. I hope I don't have to stop taking it, at least till I lose another 50 pounds or so."

• Nao...
• Taken for 1 to 2 years
• April 9, 2025

For Type 2 Diabetes "My A1C had gone up as high as 8.0, and my doctor kept adding medications to my arsenal of drugs to control my diabetes. I was taking so many drugs but was getting terrible side effects, including kidney stones, liver enzymes over 600, diarrhea, nausea, and finally, I was hospitalized and taken off all my drugs, but then my diabetes was out of control. Finally, my GI specialist recommended starting with Ozempic .5, and that's when everything started to change. At first, I didn't see much change in my weight loss, so my doctor raised it to 1mm. It was then that I saw my A1C go down to 7.2, and I had lost 10 pounds without trying. Now I have been taking Ozempic for over a year, and my A1C is down to 6.7, and I dropped 20 pounds. I don't have any side effects unless I overeat, which I avoid. If I overeat, I get an uncomfortable feeling in my stomach, but within a short period, it subsides. I wish my mother would have had the ability to get Ozempic 10 years ago, maybe she'd be alive today."

• Sus...
• Taken for 1 to 6 months
• April 24, 2021

For Type 2 Diabetes "Well, so far, my experience with Ozempic has not been great. I started out using the 0.25 mg and never had any nausea at all, no lethargy...nothing. My doctor then suggested I increase my dosage to 1 mg, and that, for me, was a HUGE mistake. I have kidney issues, and I began noticing that I was having to urinate less and less frequently, not to mention the constant nausea and extreme lethargy. I felt awful and decided not to do this medication any longer. Since quitting, I feel 100% better, my energy has come back with regular trips to the bathroom now. I would rather have my sugar be a little elevated than wind up on dialysis. For everyone that is on this medication, I wish you the best of luck, and I hope this helps your sugar levels, it just wasn't meant for me."

• Anonymous
• Taken for less than 1 month
• March 25, 2022

For Type 2 Diabetes "After 2 injections of .25, I started having watery diarrhea. On day 3, I woke up and the diarrhea had leaked out and was in my underwear. I started violently vomiting that same evening. This was day 4 of diarrhea, now with vomiting. My blood sugar levels kept crashing. I rushed to the ER, I had an X-ray, every lab work/panel you can think of, and a CT scan - nothing. Ozempic is the only culprit. I am texting this review from my hospital bed. I was admitted and put on fluids and a liquid diet. They are trying to keep the nausea under control and stop these symptoms before it affects my kidneys from being dehydrated. The Ozempic has been thrown in the garbage, but I don't know how long the nightmare from that so-called medicine will last."

• SAL...
• Taken for 1 to 6 months
• June 26, 2019

For Type 2 Diabetes "Been on Ozempic since March 2019, started off with 0.25, then 0.50, then to 1 mg. Side effects: nauseous, constipated, with fever. One month into taking Ozempic, started to have blood in my urine, no infection, CT, blood clots, bladder scope, bladder okay. CT with contrast upcoming to check kidneys, and my urine tests are concerning the PA. When giving the shot, medicine would make a bubble under the skin, then welt up 1 inch wide, 3 inches in length, and at least a .5 inch depth, 36 hours later with high fever, diarrhea, stomach cramps, large amounts of blood clots in urine, 3 times. Called Ozempic, which requested the medication back and sent a voucher for a new script. I have been taking this for 4 months, note I am not a doctor, just concerned, so I believe this could be a drug that has not been fully evaluated and may not have full understanding, or it's an odd situation for myself. However, these symptoms did not show up until on Ozempic. So for my own health, I have opted not to continue this drug."

• Sue...
• Taken for 1 to 6 months
• June 9, 2023

For Type 2 Diabetes "Within 3 days of the initial 0.25 mg dosage, my glucose was at 148. My glucose was at 260 fasting previously for months. After three months, presently at a 0.5 mg dosage, my A1c has gone from 8.2 to 6.0. I have lost 16 pounds in three months but have greatly decreased my caloric intake, so I do not credit Ozempic solely with the weight loss. I still have an appetite. Many other people who I know that are taking it say they do not even want to look at food, but that has not been my experience. I have been nauseated since day one on this drug, but I’ll tolerate the nausea for the impact on my glucose. This effect is solely due to Ozempic and diet. No other diabetic drugs are being taken. It is very convenient to use, as you only inject once a week. I am very concerned about the effect of thyroid issues/cancer in animal testing, but I guess it’s better than blindness, kidney disease, etc., that I will most certainly have if I don’t get my diabetes type 2 under control."

• Cap...
• Taken for 1 to 6 months
• May 12, 2021

For Type 2 Diabetes "I took Ozempic last October, but I had to come off it - I was so ill. I'm type 2 diabetic and Hashimoto's thyroiditis autoimmune disease. I'm 57 years old and post-menopause. The doctor decided I should try again, I started 5 weeks ago and had my 5th injection. I have been sick since I restarted. I have nausea, vomiting, diarrhea, brain fog, anxiety, burning in my stomach, headaches, and I'm so tired and weak. I tried to stick with it, I'm on the 3rd day since my 5th injection. I am so ill, I still have all the above symptoms, but worse. My kidneys are sore and my lungs. I have pain in my stomach and back. I feel like my body is poisoned, and I have to wait for 5 weeks for it to clear out of my system. I will never take this again."

• Jea...
• Taken for 1 to 6 months
• January 17, 2025

"I have been using Ozempic for 6 weeks at a dose of 0.5 mg. I am losing just over 1 kg per week. I am happy because this weight loss places less burden on my kidneys. I am focused on drinking plenty of water with Ozempic in my condition. Initially, I felt very nauseous, but now that has worn off (perhaps because I inject into my thigh rather than my abdomen?). I do not overeat anymore and am free to make healthier choices. I am not diabetic. My eGFR or kidney function is stable. My resting heart rate has increased. My doctor says Ozempic may help prevent heart issues or delay further kidney decline once I reach the dose of 1 mg per week. I am over 50 years old and have had a shingles outbreak. Not sure if Ozempic is affecting my immune system? Overall, I'm happy with Ozempic and its ease of use."

• Dee...
• Taken for 1 to 6 months
• March 18, 2021

For Type 2 Diabetes "Ozempic lowered my A1C, and I lost weight due to the constant nausea and diarrhea. When I was on the 0.25 dose, the stomach issues were there but not as severe. Once I went up to the 0.5 dose, the diarrhea was constant. I lost over 22 lbs in 4 weeks. I was unable to eat most foods because I lost my taste or the food made my stomach turn. I became severely dehydrated and ended up in the hospital for 3 days because my potassium and magnesium were at dangerously low levels, as well as my kidneys were not working properly. Needless to say, I will never use this medication again."

• fem...
• Taken for 6 months to 1 year
• September 23, 2023

For Type 2 Diabetes "Serious stomach issues, cramping, bloating, severe constipation, nausea, no appetite, rashes, pain in the upper and lower bowel, gas. Loss of too much weight, no taste for food. Have had previous trouble with colitis and diverticulitis but still prescribed this medication. Only have 1 kidney and now afraid it may be damaged. I have been on this drug for approximately 7-9 months. Now worried, but the doctor is not concerned enough to take me off this medication."

• Nev...
• Taken for less than 1 month
• April 28, 2021

For Type 2 Diabetes "I started this drug at 6 pm on Sunday, and by 9 pm, I was feeling nauseous, so I went to bed early, hoping to feel better when I woke up. At 3 am, choking on my own vomit. After puking my guts out, my right kidney felt like it had been punched about a dozen times and my stomach pumped. Felt lightheaded. Talked to my doctor on Monday, and he gave me instructions for rehydrating, so I followed instructions hoping to feel better the next day. No way, instead my symptoms worsened to include diarrhea, and I almost went to the ER but could barely walk, let alone drive. It’s been 72 hours since I’ve had any food at all. The doctor said today that I should feel better tomorrow...he said that yesterday, too. Hopefully, he’s right. This medication is the worst! I do not recommend and will not take anymore."

• Ore...
• January 17, 2020

For Type 2 Diabetes "I was on Ozempic for 8 months. Nausea and vomiting and kidney stones. Kidney stones every month I was on it. Had to have surgery twice. Went off Ozempic, no more kidney stones."

• Oze...
• Taken for less than 1 month
• September 12, 2022

For Type 2 Diabetes "Major nausea and vomiting. Hope it leaves soon and only second day. Also, kidneys are sore and stomach aches."