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Pseudoephedrine / triprolidine and Drowsiness: What Users Say

Brand names: Aprodine, Allerfrin, Hist-PSE, Ed A-Hist PSE, Allerfrim, Allercon, Genac, Allerphed, Aphedrid, A-Phedrin, Actedril, Atridine, Atrofed Atrogen Hista-Tabs Vi-Sudo Actagen Altafed Biofed-PE Histafed Actacin …show all brand names

Drowsiness: mentioned by 4 users (16.0%)

Based on user experiences from 25 Pseudoephedrine / triprolidine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

drowsiness 16.0%
dry mouth 16.0%
sleepy 12.0%

Reviews for Pseudoephedrine / triprolidine

Commonly mentioned side effects
  • LLa...
  • October 20, 2009

Pseudoephedrine / triprolidine for Cold Symptoms "When used for colds, Actifed works well for drying up post-nasal drip that causes near-constant coughing, especially at night. It does cause drowsiness, but not a problem for nighttime use. I can get a nearly full night of rest. However, with subsequent use on following nights, Actifed's effectiveness lasts only half as long."

8 / 10
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14 Report
  • Min...
  • February 9, 2012

Pseudoephedrine / triprolidine for Cold Symptoms "This is my absolute favorite for colds with a runny and partially blocked nose, itchy and watery eyes, and sneezing. This antihistamine does make me drowsy a tiny bit, but I can go to work as normal and don't really see any difference. I tried combining some other antihistamines and phenylephrine, but I keep going back to good old Actifed. The only downside - it really makes my mouth and throat dry, so I guess I might try taking half of the tablet instead."

9 / 10
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9 Report
  • Mat...
  • Taken for less than 1 month
  • January 2, 2018

Pseudoephedrine / triprolidine for Cold Symptoms "Every time I have a cold, this is the only OTC drug that makes going to work possible. Occasionally makes me drowsy, but it dries the cold up really well. Need to drink a lot of water, as you get a slightly dry throat."

9 / 10
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3 Report
  • bln...
  • February 28, 2015

For Cold Symptoms "This product dried up my sinus very well, however, it made me extremely drowsy, so all I wanted to do was sleep. I experienced dizziness as well. I would suggest nighttime use but not during the day. I couldn't drive or work in this condition."

8 / 10
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1 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.