Compazine and Nausea: What Users Say (Page 2)
Reviews for Compazine
- mig...
- Taken for less than 1 month
- August 1, 2022
For Anxiety "I had a severe migraine for 2 days. I was in so much pain I had blurred vision and nausea. Tried to take my prescribed PRN migraine medicine, but I threw up. The ER nurse gave me pain meds and fluids in my IV, as well as steroids. She came back and said the doctor had ordered Benadryl and Compazine for me. I asked what it was, I have always been given Zofran. She stated it would help with the nausea. She added the syringe of Compazine to my 1000 ml bag of saline. But she did not mix it, the bag was already hanging. I do believe I got a much larger amount administered at one time because of how she added it to the hanging bag. Within 5-10 minutes, I was panicking, couldn't sit still, but I was too dizzy to stand. I tried ripping the IV out, crying at my husband that we needed to leave. I couldn't explain why I was upset or answer his questions other than I needed to go/get out. The IV needed out. The nurse came and stopped the IV. Took 30 minutes for the panic, terror, and confusion to pass."
- RTa...
- Taken for less than 1 month
- August 8, 2019
For Nausea/Vomiting "I took half a pill, and it made my whole face go numb. This is the worst drug I've ever taken. It made my stomach so sick I thought I would be throwing up for days. Run, don't walk from this medication."
Frequently asked questions
- Mig...
- Taken for less than 1 month
- March 30, 2023
For Nausea/Vomiting "I've had Compazine a few times due to suffering from severe migraines. It's never pleasant, but I was trying to make it to a shift at work, so I asked if I could have the migraine cocktail without whatever makes you so tired (Benadryl). I quickly learned this was a huge mistake. After they put this in my IV, I started shaking uncontrollably and could barely stay in bed. The shaking and spasms quickly became painful, and it did not help with the nausea at all because I threw up a few minutes after receiving it. I had pressed the call nurse button before the vomiting and asked for literally anything to stop whatever was happening. They gave me some Benadryl through the IV, which did help somewhat, however, I'm sure it was just because they gave me enough to knock me out. My review doesn't even come close to describing how God awful this medication actually is. If you're ever offered this for nausea, ask for something else or just throw up, I promise it's better than taking this."
- Moo...
- July 11, 2021
For Nausea/Vomiting "I went to the ED July 10, 2021, for feeling dizzy and nauseous (come to find out I had fluid behind my left ear). Anywho, they gave me Compazine and Benadryl. Let me just say I felt worse leaving the hospital than going in. My dizziness and nausea went away, but I left the hospital feeling like a psych person. My body couldn't stop moving, but at the same time, I was extremely tired. I couldn't even drive home. This drug should definitely be off the market. It took a little over 14 hours to get out of my system."
Are you taking this medicine?
Your review helps others make informed decisions.- LAV...
- Taken for 10 years or more
- March 24, 2021
For Nausea/Vomiting "It was 1975 when I was 15. I had the flu for several days, vomiting every 15 minutes or so. The doctor prescribed Compazine. I only took one or two pills when my head turned uncontrollably to the left and then to the right (similar to having a stiff neck), but I was no longer nauseated. Later that evening, my eyes started rolling back in my head, and my head snapped back so that I was basically looking behind myself. I panicked and started taking off my clothes and running around the house. My mom took me to the ER. I had to find the drug in the PDR so they knew what I had taken. It was bad and scary."
- Me4...
- Taken for less than 1 month
- April 22, 2021
For Nausea/Vomiting "I was prescribed this medication after vomiting for days on end and becoming dehydrated. (It was later found that I had a bad case of reflux which was being aggravated by my birth control.) After an IV of fluids to hydrate me, the ER doctor sent me home with Compazine. It helped with the nausea, and a couple of days later, I was able to get back to my daily activities. However, that second day, I began to feel like I was having a hard time getting a full breath in. Luckily, someone was home with me and my 2-month-old infant because my tongue felt like it was swelling, then my teeth began to grind, the muscles in my neck clenched, and I couldn’t make any of it stop to even be able to use the phone. My family rushed me to the ER where I was given a shot of steroids to stop the anaphylaxis I was suffering from. This drug is now on my allergy list. Worst experience with a prescribed drug!"
- Han...
- Taken for less than 1 month
- July 3, 2021
For Nausea/Vomiting "Goodness me, I went for extreme abdominal pain and nausea with vomiting and was given this since Zofran did not work at home prior to my arrival. I was already somewhat concerned as my partner had been given Compazine as part of a migraine cocktail and had the worst panic attack of their life. They administered it to them right into the arm; however, mine was being put through the IV saline bag as a slow drip, so I wasn't that worried; I figured it would infuse slow enough it wouldn't bother me. Boy, was I wrong. About 5-10 minutes later, I was so warm and overheated, my hands went numb as I began to panic for what seemed like no reason. I was full-on shaking and hyperventilating, as well as feeling trapped and somehow more nauseated than before. The initial panic lasted maybe 15 minutes, but I felt on edge for the rest of the day and like I was still fighting off a panic attack."
- ALg...
- October 10, 2021
For Nausea/Vomiting "While on vacation, I went to the ER with dehydration and nausea, was given IV Compazine, and discharged. On the way home, with my husband driving, I began having thoughts of jumping out of the moving car! Once back at our rental house, I began pacing, couldn't sit still for more than a few minutes, felt my heart beating wildly in my chest, had an astronomical BP (which I only have problems with when I am anxious, but I do monitor on a daily basis), and considered jumping off the two-story deck more than once. I've never considered jumping out of a car or hurting myself in any way until receiving this medication. I literally felt as if I was going to come out of my skin due to extreme agitation. Finally, after about 6 hours of this nightmare, the effects began to wear off, and I've been okay since. I have no allergies to anything else, but I consider this incident the result of some sort of allergic reaction and now list it as such in my medical history everywhere I go. Proceed with caution!"
- Jos...
- Taken for less than 1 month
- February 9, 2022
For Nausea/Vomiting "I went to the ER for a severe migraine with nausea and stomach pain. I was given an IV cocktail of Toradol, Benadryl, and Compazine. Within 3 minutes of injection, the room went completely black, I thought I was going to faint, a wave of heat overcame my entire body, and my heart rate skyrocketed. I thought I was dying. I had an extreme urge to leave the hospital, I felt that I was not safe. I hit the call button over and over, begging for someone to help me. I was extremely restless, my jaw was chattering, I couldn’t stop moving my legs, I felt like I was crawling out of my skin. The nurses had to perform an EKG on my heart as I started having abnormal heart rhythms. After 20 - 30 minutes, I was able to calm myself down, however, I kept jerking awake with every sound, movement, or voice. I was admitted for observation overnight and hooked up to a heart monitor until I was released. Nurses said these are common side effects after the fact. I will never take Compazine again!"
- Min...
- Taken for less than 1 month
- October 9, 2023
For Nausea/Vomiting "I was in the hospital for diabetes, sugar level being increased. Well, on day 3 of me being there, the nurse asked me if I was nauseous, and I stated yes. However, I should have said no because it wasn't to where I needed medicine. He came back with a medicine and put it in my IV. Five minutes later, I jumped out of the bed on both feet. My heart was racing, I was burning up, I couldn't calm down, I ran to the nurse's station to get the nurse. He ran in the room to message the doctor to order a medicine. While he was typing, he stated, 'I bet it's the medicine I just gave you.' I asked why, have you seen people act this way afterward? He says, 'Yes.' So, why in the hell are you all not pre-warning people about this medicine? Now that I have discharged over a month ago, I have been having panic attacks randomly. At this time, it has been at least 5 over the last 30 days. My primary care sent me to a therapist. She said she thinks this is an isolated event and do not want to diagnose me with anxiety."
- Gri...
- Taken for less than 1 month
- May 8, 2022
For Nausea/Vomiting "I had a migraine, had this through an IV with Benadryl, Toradol, and obviously Compazine. Within 5 minutes, I had nausea. I had a panic attack and could barely breathe. I tried to take the BP cuff off. I had anxiety and felt like I couldn't fall asleep. I fell asleep in the hospital bed after 15 minutes of pure torture and slept for 45 minutes. I woke up, barely able to breathe. I got discharged and went back home. The headache was gone, but I felt like I could barely breathe. Some depression was triggered, I wanted to die. I couldn't even take a nap, even after 45 minutes. I couldn't do anything, reading a book was awful, browsing the internet was awful. Side effects wore off after 48 hours. I had the exact same experience next time I had horrible migraines. I wish I just had the migraines."
- Alm...
- Taken for less than 1 month
- October 1, 2021
For Nausea/Vomiting "I was prescribed this junk after having my gallbladder removed. Long story short, I had a severe allergic reaction that caused lockjaw, nausea, and my throat to close. I was on my deathbed two nights in a row. Literally sucking in as much air as I could as my throat was closing. ER saved my life. Worst meds ever!"
- Com...
- August 15, 2021
For Nausea/Vomiting "Scariest medicine in the world. Was given Compazine yesterday night when I was admitted to the hospital. Doc gave it to me for nausea and anxiety. Made it worse! I had suicidal thoughts, wanted to check myself out of the hospital but couldn’t because I was losing so much blood. My legs and arms are restless even a day after. I’m so mad I was given this drug after seeing all these reviews and all the same side effects. So sad."
- Anonymous
- Taken for less than 1 month
- November 5, 2019
For Nausea/Vomiting "I agree with the review about how all these other reviews have identical symptoms. I too question if they are for real. I had a migraine and severe nausea, and a simple 5 mg over an hour's time worked for me."
- Pri...
- August 29, 2022
For Nausea/Vomiting "Went to the ER with horrible migraines that I haven't had in many years. Also was nauseated from the migraine. The nurse came in, took blood, then gave me the medication. This medication made me feel amazing. I read all the reviews, and being on medication for many mental illnesses since the age of 16, I know this for a fact: the ones who had the crazy side effects were having that reaction because they definitely don't have anxiety. Anytime my doctor would say try this medication, and I would get bad side effects, I would look up what the medication was for. If it wasn't the right medication for what I was suffering from, I would have horrible side effects. It was meant for a different illness. Most medications say they work for a certain complaint, but if you aren't suffering from that illness, you will have crazy side effects."
Are you taking this medicine?
Your review helps others make informed decisions.More about Compazine (prochlorperazine)
- Compazine consumer information
- Check interactions
- Compare alternatives
- Reviews (298)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Support group
- Drug class: phenothiazine antiemetics
- Breastfeeding
For Nausea/Vomiting "Uh... No, just no. I was given this through an IV at the ER for nausea because of issues with my gallbladder. Seconds after getting this, I felt extremely hot. I was so agitated my leg was moving like crazy, and my lip and teeth were gripping together so badly that I thought I was going to break my teeth. I was asking the doctor to let me leave. They had to give me Ativan to help me relax, and thank God that worked. I never in my life want to be on that medicine again."