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Pregabalin for Neuropathic Pain User Reviews (Page 4)

Brand names: Lyrica, Lyrica CR

Pregabalin has an average rating of 5.7 out of 10 from a total of 330 reviews for the treatment of Neuropathic Pain. 44% of reviewers reported a positive experience, while 35% reported a negative experience.

Reviews for Pregabalin

  • Chemo...
  • Taken for 1 to 6 months
  • June 20, 2014

Lyrica (pregabalin) "I too progressed from Gabapentin to Lyrica, 100mg 3x a day. I have chemically-induced neuropathy from 6 months of chemo. My hands and feet are numb, tingling, like they are asleep. Lyrica is supposed to be an advanced form of the Gabapentin, though I have seen little difference. I have increased appetite and some swelling in my hands and ankles. I continue using Lyrica because I need something for the hot shooting pain. This was the last med prescribed for my neuropathy."

6 / 10
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  • Lose-...
  • Taken for 1 to 6 months
  • July 1, 2019

Lyrica (pregabalin) "My mother suffered a stroke in February. She went through rehab and then skilled nursing care where she was prescribed Lyrica for restless leg. She left skilled nursing care with slight movement in her right leg following about seven weeks of therapy. We took her into to see her doctor of 30 years about five weeks ago. Due to his experience, he took her off Lyrica straight away. Almost immediately she stopped crying (would without fail cry every second or third day I visited her). AND, she actually started moving her leg more than she ever has. Both things (crying and leg movement) improved immediately. Her doctor said he's seen psychotic behavior result from taking it. I would absolutely not recommend taking this drug."

1 / 10
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  • neeta...
  • Taken for 1 to 6 months
  • May 20, 2014

Lyrica (pregabalin) "After spinal surgery I was having shock life pain and tingling in my hands and feet all the time. After about a month on Lyrica that pain had calmed down and I was sleeping much better. I do feel somewhat sleepy when I take it but nothing too out of control. I hope I can cut it out in a few months as I hate to be in any medication very long."

9 / 10
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Frequently asked questions

  • fimmy
  • November 7, 2016

Lyrica (pregabalin) "Have been on Lyrica for six months now for lower back pain. At first, 2x25mg per day. With doc's approval moved to 1x25mg per day. Now, 1x75mg, three times per week. The effect has been enormous. Pain gone. Thanks to Australian health system, costs are about $6/month"

10 / 10
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  • RNinp...
  • Taken for 5 to 10 years
  • May 7, 2018

Lyrica (pregabalin) "Lyrica is very effective for the radiculopathy (nerve pain that radiates into the lower extremities) I suffer as a result of multiple back issues. The key to minimizing side effects is to start on the lowest dose possible. I've noticed many doctors start at the max or even higher, even if you're new to the medicine. This is why so many people have so many side effects. I have few if any side effects and it's the only thing that works for my leg pain. I could barely sit without it, the pain was unbelievable. Now it's manageable. If this medicine is something you and your doctor are considering, ask to start at the lowest dose and only increase it if you're not getting relief. Many of the posters I see here with severe side effects are on 300-600mg a day when the max recommended dose is 300mg a day. Of course I don't blame patients for not knowing this. They should be able to trust their doctor. This medication can be so very helpful if used and prescribed correctly."

9 / 10
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Are you taking this medicine?

  • JR 15...
  • October 21, 2015

Lyrica (pregabalin) "I recently had back surgery for spinal stenosis. I was having leg pain and the pain in my leg was worse than before surgery. After surgery I was also experiencing new pain of stabbing, electrical sensations in addition to the pain I previously had. I was prescribed Neurontin and the doctor kept raising the dose with no difference in my pain. I heard of similar experiences and being switched to Lyrica and it made a huge difference. I was in so much pain day after day. I switched to Lyrica and I have had nearly full relief of the pain I was having. I can't even describe how much this medication has helped me. If you find yourself in the same experience there is hope. Keep communicating with your surgeon and try Lyrica."

10 / 10
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  • Tucker
  • Taken for 1 to 6 months
  • August 18, 2018

Lyrica (pregabalin) "I have RA, degenerative disc disease (DDD), fibromyalgia, and terrible body aches for 15 years. Used gabapentin in crazy amounts with little or no relief, I finally got on Pfizers patient assistant program 3 months ago. I have taken Lyrics 75mg twice/day coupled with diclofenac gel 3% and I can say I am in the least amount of pain I have experienced in 20 years. No narcotics either. This is a miracle drug for me. Please ask your Dr. For a sample even if gabapentin did not work for you. You will get your life back like I have.. T"

10 / 10
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More FAQ

  • DjayR
  • Taken for 5 to 10 years
  • May 12, 2017

Lyrica (pregabalin) "I've had 6 spine surgeries in 5 yrs. I suffer from neuropathy and nerve pain to severe levels. With this new trend, by an insensitive Congress, to take away opioids I couldn't imagine being without Lyrica. The only side effect is memory loss, only short term memory. I don't mind. If you suffered my pain you wouldn't either. I've never felt high and taken it for 5 yrs. 75mg x 3 daily. I'm grateful for it. I would suffer so bad w/o it."

8 / 10
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  • Mars
  • Taken for 1 to 6 months
  • January 14, 2016

Lyrica (pregabalin) "I recently stopped taking lyrica after 6 months. I was taking lyrica for nerve pain following a terrible car accident. I wish I had never started taking lyrica. It not only did not help with the pain but only made my condition worse, not to mention the 30 pounds of weight I put on. Also the horrible withdrawal's was worse than I ever could of imagined. I absolutely do not recommend ever starting lyrica"

1 / 10
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  • Mandi_x
  • Taken for less than 1 month
  • July 27, 2017

Lyrica (pregabalin) "I was started on this medication by an Emergency department doctor as I was taken to hospital with numbness down my left side... Turns out a twenty year old fracture in c2 and c3 in my spine cord has fused together and is pinching a nerve... Been sent for a CAT scan will report back... 75mg Lyrics twice daily.. Pain, nausea, gone anxiety moodswings(ptsd) gone... The numbness is still there but bearable.. I love this stuff so far... No side effects what so ever so far 3 days in... Will report back later if anything changes"

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  • Gen
  • May 23, 2013

Lyrica (pregabalin) "I have been on Lyrica for only a few months for neuropathy pains. I also have lupus, arthritis, fibromyalgia, and gastrointestinal issues. Lyrica worked excellent the first few weeks for the neuropathic pains. After a while I noticed I started to have more lupus flares and joint irritations. It is causing me to gain weight which is a plus because my other medicines was causing me to loose weight. I have tried a lot of medication including gabapentin (3600mg daily) and Lyrica worked best overall."

6 / 10
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  • Jennb...
  • Taken for less than 1 month
  • February 19, 2014

Lyrica (pregabalin) "This medicine was my neuropathic calming wonder medicine until my body over the course of several years had progressed to full body pain. I recommend anyone who has new or has out grown their pain medication to talk to your doctor about this."

7 / 10
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  • Jess
  • Taken for 5 to 10 years
  • March 30, 2018

Lyrica (pregabalin) "I guess I'm one of the lucky ones because Lyrica has changed my life - it is a miracle drug. I would recommend it to anybody. I have been on it for 7 years now and it works great for me. I take 300 mg two times a day and I don't even think about my nerve pain anymore. After the first week I started taking it started working for me I wish everybody had the same experience I'm sorry that they don't. I hope that those people something that works out"

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • May 11, 2016

Lyrica (pregabalin) "I took lyrica for long standing neuropathic pain. I took it before bed and woke up the next day completely in a haze, dizzy , uncoordinated and could not function. It made my symptoms worse. The dose was 150 mg. I am just sharing my experience. Unfortunately it is not helpful for me."

1 / 10
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  • mspig...
  • Taken for 1 to 6 months
  • May 27, 2017

Lyrica (pregabalin) "Been taking lyrica for 4 months now for carpel tunnel and neuropathy in hands and feet. It is no good. It has not stopped the pain at all, makes me so dizzy I am afraid to drive my car, legs swell like balloons, and have gained over 30 pounds in 3 months. A clinical research was recently done in Australia on lyrica (for Acute and Chronic Sciatica) and the findings stated it had the same effect as the research subjects getting placebos or sugar pills. The makers have racked in 3 billion dollars on it. I told my doc it isn't working but he still prescribes it to me, finding another doc this week. I just got a months supply, 90 pills 3 times a day, 150 mg at a cost of $1,111.19. Biggest drug ripoff in history."

1 / 10
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  • pain_...
  • Taken for 6 months to 1 year
  • March 27, 2017

Lyrica (pregabalin) "I would not recommend Lyrica to anyone. I had severe neck pain and nerve issues, and prescribed Lyrica, slowly increasing my dosage. I was up to a total of 300mg twice a day and the medicine had an issue with the Zoloft I was taking causing Serotonin Syndrome. I didn't feel a significant change in pain after taking Lyrica for over 3 months. After I had my neck surgery, I started slowly decreasing my Lyrica. It has absolutely been the worst medicine to come off of. Decreasing dosages as small as 25mg impacted my whole life. I couldn't stay awake, was in a cloud, felt nauseous and completely un-motivated. If I ever knew these side effects were a potential I would have never started taking this med. Advise taking with caution!"

1 / 10
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  • Kskin...
  • Taken for 2 to 5 years
  • February 25, 2017

Lyrica (pregabalin) "I have L5/S1 disk herniation and this medication had saved my life, I can walk and stand for long periods of time again thanks to this medication. This had been a life saver. I use the Co pay card from the Lyrica Web site."

10 / 10
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  • James...
  • Taken for 1 to 6 months
  • June 5, 2016

Lyrica (pregabalin) "I have had neuropathy for some time and tried a host of other medications before trying Lyrics. I was on it for slightly over 3 months with my dosage starting at 75 mg twice a day to 300 twice a day. Initially the pain was approximately 7-8 and the Lyrics got it to about a 5 routinely with some days worse. However I suffered from some of the side effects stated by it's manufacturer including dizziness, being off-balance at times, problems with sleep and concentration, and weight gain. (Approximately 20 pounds over 3 mos. and it's resulting effect on increasing my A1c.The) worst part was an increase in anger. After no subsiding of the side effects my Doctor suggested I cease using it. We are looking for alternatives."

4 / 10
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  • Daugh...
  • Taken for less than 1 month
  • October 19, 2018

Lyrica (pregabalin) "My Mother in-law takes Lyrica for Neuropathic foot pain from PAD she is not diabetic. It is very helpful to her. When she doesn't have it she cannot walk and is in a W/C, but with the Lyrica she is able to walk with barely a cane. She said she still can feel a little something on the bottom of her feet but she can tolerate it. Hopefully this will last."

9 / 10
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  • Nomor...
  • November 5, 2015

Lyrica (pregabalin) "Horrible medicine. I had a nerve injury and this medication only made things worse. Mental and emotional side effects were substantial, and I had no history of depression or mood changes before taking Lyrica. Since I stopped taking it, I feel like myself again and feel like I am handling pain better because I am not feeling depressed by my medication. I am so relieved I am not taking Lyrica. I would not recommend it to anyone. The side effects completely outweigh the minimal benefits."

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  • CCBEAR
  • August 24, 2017

Lyrica (pregabalin) "Started having horrific leg stabbing pain, feet numbness and tingling not a pins and needle pain and freezing cold hands and feet! My doctor sent me to neurologist he thought maybe MS! 2 hours of different testing and found that when I stand with eyes closed I guess I sway really bad! EMG came back Peripheral Neuropathy Idiopathic! I'M NOT DIABETIC! PAIN SPECIALIST started me on Lyrica back in 2011 June and I LOVE it! I can walk now without crying! I also have tried tons on pain pills and favorites are Roxidone 15mg take as needed and I Fentynal patches and Norco 10s when needed but after years of trying everything from Morphin, Methadone,Cymbalta, klonopin,ect ect LYRICA is the winner! Only take that 1 pain pills in am now, use to take 5"

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  • Rowena
  • Taken for 1 to 2 years
  • February 27, 2024

"Pregabalin has been fantastic for my pain issues. I am living with several chronic pain conditions: interstitial cystitis, instability of the ankle joints causing frequent sprains and surgery, two bulging discs in my spine, and a peripheral nerve injury (neuroma) with chronic regional pain syndrome. With pregabalin, I am able to manage a lot better than without it. I do get some side effects like some cognitive issues, but it’s definitely worth it. Sometimes I have taken 100 or 150 mg three times a day. I have also tried twice a day, but I get a lot more breakthrough pain doing that so I recommend three times a day as better, in my experience. I find it less helpful for my bladder and orthopedic pains, and most helpful for the neurological pain in my hand and also my back pain. It’s very important to take it on schedule because there are bad withdrawal symptoms, so I also recommend you reduce it very slowly, unless it’s an emergency. Also, I think it’s better than gabapentin!"

10 / 10
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  • P Win...
  • September 21, 2015

Lyrica (pregabalin) "I was prescribed Lyrica for small fiber neuropathy pain. I will say it did offer relief from the pain but the side effects were just too great and at times dangerous. You should not be driving a car on this stuff. I was in an accident because I was slow to reaction in a high stress traffic situation. You will eventually begin to feel quite unlike yourself. Zombie like. You will say to yourself, I don't feel like me anymore I feel like something is controlling me. If you're someone who can stay home all the time and has very little work demands, or family life this may be helpful to you. Understand that the zombie like feeling and slowed reaction time will be an issue. gabapentin was a safer choice in my opinion even with side effects."

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  • Pain...
  • Taken for less than 1 month
  • October 9, 2015

Lyrica (pregabalin) "I rated Lyrica as "one" because IF your prescription plan does not pay for it, it is worth nothing to you UNLESS you are prepared to pay about $350.00 a month out of your own pocket. It's effectiveness for a few of my problems was very good, but since I cannot afford it, it's effectiveness is actually ZERO to me now. Don't take the free sample that will be offered to you (unless you can afford it later). Stopping Lyrica will be the one of the most miserable things you have ever tried in your life! It is a horrible withdrawal. the company is just like a street dealer of drugs. BOTH give you "free samples" to get you dependent on the drug and they charge big money for you to continue taking it."

1 / 10
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  • nana...
  • Taken for less than 1 month
  • June 7, 2015

Lyrica (pregabalin) "Had spinal fusion in Jan 2015. I had severe nerve damage due to spinal stenosis. I had terrible burning pain in my entire right leg. Opiates did nothing for it. I have only been on lyrica for a week and I definitely feel somewhat of an improvement . I am hoping it gets even better in the coming weeks."

7 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.