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Pregabalin for Fibromyalgia User Reviews (Page 5)

Brand names: Lyrica, Lyrica CR

Pregabalin has an average rating of 6.4 out of 10 from a total of 362 reviews for the treatment of Fibromyalgia. 53% of reviewers reported a positive experience, while 27% reported a negative experience.

Reviews for Pregabalin

  • Khano
  • Taken for less than 1 month
  • February 2, 2019

Lyrica (pregabalin) "I’m a mess I have several issues medically CRPS (Chronic regional pain syndrome) in my left limbs my arm wrist & fingers are non functional due to a carpal tunnel procedure it went untreated so it spread to my leg & foot ,Fibro as well as deg disc disease. My mobility is 200ft is the furthest I can walk. I have a new PCP I’m on Fentanyl trans patch 25 mcg last 4 yrs I just started lyrica. My issue is gaining weight it’s already a struggle to walk & i can’t carry extra weight else I won’t be able to walk. I’m prescribed 50mg 3x a day I just wanted to know about weight gain I appreciate any feedback"

10 / 10
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  • Monkey
  • December 31, 2016

Lyrica (pregabalin) "I wanted to share my experience in combining Lyrica and Neurontin for neuropathy symptoms; I've had fibromyalgia for 25 yrs. Neurontin was effective, but only at 1800 mg./day, which left me drowsy (fell asleep anytime I wasn't moving). My MD switched me to Lyrica (75 mg), but when I got to 3 per day, I rapidly gained weight - 10 lbs. in 2 wks! As a med student, I knew the two meds worked in a similar way and were metabolized similarly. I decreased the Lyrica to 1/ day, which stopped the weight gain, but didn't control the nerve pain, so I added back in one 300 mg. Neurontin per day (both at bedtime, to minimize drowsiness) - still not enough pain control. I added another Neurontin, and that was optimal for me. I take it all at bedtime."

10 / 10
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  • Lital...
  • Taken for 1 to 6 months
  • August 12, 2016

Lyrica (pregabalin) "I was just diagnosed with fibromyalgia earlier this year. My old doctor prescribed me Cymbalta and it didn't work. I was off from work for 2 months because of the pain. All I did was layed in bed suffering. Seemed like I would never have my normal life back. I went to another doctor and he prescribed me Lyrica it lessened the pain within a day or two. Now I have some of my life back. I still have a little pain but Lyrica has helped me and changed my life."

9 / 10
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49 Report

Frequently asked questions

  • Sandymc
  • May 22, 2017

Lyrica (pregabalin) "I have suffered from headaches for years with relief with Excedrin. However, I was taking up to 8 at the onset to keep it from becoming a migraine. I'm really surprised that the Drs didn't tell my about "Excedrin abuse" since I told all that I was taking that much. However, when prescribed Lyrica for fibro pain, my headaches were gone to maybe 3 a week. So I highly recommend this for serious headache problems. Does help with Fibro pain. But, weight gain and dry mouth are my biggest side effect and is to the extent that I almost want to go back to 8 Excedrin a day. Hope this helps someone!"

7 / 10
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  • Alice...
  • Taken for 1 to 2 years
  • January 5, 2014

Lyrica (pregabalin) "I found this to be very effective in treating the after effects of double fusion of cervical vertebrae. Then I found I was having less difficulty with fibromyalgia. I was on 3 a day and only side effect was weight gain."

10 / 10
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Are you taking this medicine?

  • the...
  • Taken for 1 to 6 months
  • July 25, 2015

Lyrica (pregabalin) "I've had fibromyalgia for about 30yrs - I am 43. Endometriosis from ages 13-36, (a hysterectomy 'fixed' that;) clinical depression from abt 16, (break down at 28;) anxiety disorder; insomnia &/or severely disturbed sleep cycles for15-20yrs. AND I've needed a cane to walk for the last 2-3 yrs. FMS & depression compete for the title of "most debilitating." I've tried almst everything, (Cymbalta was useless.) The last 2 months I've been taking slowly increased doses of Lyrica. Currently on 150mg a day, (2× 75mg,) with a view to 300-400mg. I've had zero relief from pain, BUT nasty side fx. Almost no sleep. Worsened depression & anxiety. Terrible FMS type 'fog.' Flatulance! Cannot see this contiuing or improving. (Available on PBS in Australia.)"

1 / 10
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  • Diana...
  • February 2, 2013

Lyrica (pregabalin) "I have been on Lyrica for a week now, 150 mg only at night and have not felt this good in three years. I am move active. I have not gain any weight yet, but hopefully be as active as I am now I will lose weight."

9 / 10
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64 Report

More FAQ

  • krism...
  • April 11, 2013

Lyrica (pregabalin) "This medicine worked pretty well for me. I didn't realize how well it worked until I went off of it before getting pregnant. The thing I didn't like about it though was that it always made me feel like I was in a cloud. My thinking wasn't clear. I would get dizzy. I didn't notice too much of a weight gain, but there was some. In the end, I chose to try a different med (Savella) after my daughter was born and have been happier with that. Still works and fewer side effects."

6 / 10
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  • Living
  • March 31, 2008

Lyrica (pregabalin) "I have had FM for 20yrs, been on morphine,anti depressants, Fentanyl patches - you name it I have tried it, but thank the lord for Lyrica which I started in March 2008. It has made my life worth getting up for in the morning. I can do things I was not able to do for so long. "

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • April 23, 2019

Lyrica (pregabalin) "I was prescribed 50 mg Lyrica twice daily and it helped slightly for a few days and then did absolutely nothing for my nerve pain/ fibromyalgia. I'm sure it works great for some people but for me the only thing it did was give me panic attacks, make me extremely depressed and altered my sense of taste. When I wanted to get off of it I got a new script for a wean and I had to phone lyrica to try to get to their patient assistance department since it is so expensive, even with the savings card and I should qualify for assistance. However I never got thru because their customer service insisted on interviewing me about my wean before they would put me thru to patient assistance. I shouldn't have to go thru 3 people to answer a yes or no question about assistance especially when I don't feel comfortable giving them my health records over the phone."

2 / 10
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  • Big...
  • May 16, 2017

Lyrica (pregabalin) "My doctor prescribed Lyrica for fibromyalgia, this was the worst medication I have ever taken! Within a few days, my anxiety levels were through the roof . I had other side effects too but I can't recall what they were now - it's been a horrendous year."

1 / 10
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  • LWSou...
  • April 27, 2017

Lyrica (pregabalin) "My doctor prescribed Lyrica for fibromyalgia. As I am very sensitive to medication, I was prescribed 75 mg at bedtime each night. The first month, I did feel better taking Lyrica. However, after about 4 months I began experiencing strange symptoms. I could not remember things. My brain was foggy. I wasn't myself and my pain returned. It was a no brainer, so I informed my doctor that I wanted off of this medication. I've been off Lyrica now for two months and my brain is back to normal. It was very scary to even think how little I was taking and what an impact it made on me. I am taking apple cider vinegar with honey every morning, exercising a little day, even if I don't want to, and resting when my body needs it."

1 / 10
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  • Summe...
  • October 20, 2016

Lyrica (pregabalin) "Works pretty well for the pain, but having severe side effects (involuntary musclular movement involving jerking of legs and difficulty speaking, urinary retention and inability to urinate, dramatic weight gain of 30 pounds so far)"

6 / 10
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  • Jll
  • Taken for less than 1 month
  • October 4, 2018

Lyrica (pregabalin) "I have Rheumatoid Arthritis and Fibromyalgia. I have only been taking Lyrica, 75mg twice a day, for a week. The first 4 days I felt "spacey", but that is going away. I immediately felt better. I have been on hydrocodone, then oxycodone. They were not helping much. My pain Dr did a cheek swab gene-drug reaction test. There were only two opiates that were compatible with my DNA. I've been on Nucynta, regular and ER for maybe 5 months. Still taking it and EC naproxen, Plaquinel. It was helpful for some of the pain, but not the nerve and muscle pain. I don't have any side effects so far from Lyrica. I will update if anything changes. All I need to say is I feel 85% better. I also feel better mentally and feel like doing things I haven't been able to til now. I'm taking a free trial, it hasn't been submitted through insurance yet. There is a discount card on website for $35 instead of insurance."

8 / 10
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  • Anonymous
  • March 7, 2008

Lyrica (pregabalin) "I have had fibromyalgia for 12 years and have been on high doses of morphine,durogesic patches, methadone, and many other narcotics. I am now on 225mg of lyrice twice a day and low doses of opana. I feel like a new person, never though it would every happen. I feel like a did years ago and I am 63 now but am able to do most of the things I was able to to before the fibro hit me. I can"t work my old job as an RN but I can do most things. Some days are better than others but this is a great drug."

10 / 10
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  • Murr
  • June 14, 2017

Lyrica (pregabalin) "I started taking lyrica 25mg 2 weeks ago. I was sleepy day 1, took nap. Next day 25mg felt well and energetic. I'm combining low dose which a massage every 2 weeks. I'm interested in what others have to say about long term use at a low dose."

8 / 10
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  • Alicat
  • January 10, 2016

Lyrica (pregabalin) "I started taking Lyrica about 8 months ago. In about 3 days I had felt a significant change. It was working great for my Fibro, but I also have spinal arthritis. It did nothing for that or my sciatica. Finally I was bumped up to high dose, but do to other things in life I had to stop because of financial difficulties. I couldn't even afford copays. So I'm on gabapentin and it barely works. If I could, I would get back on Lyrica! Thank you all for sharing your experiences!"

6 / 10
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  • Great...
  • Taken for 1 to 6 months
  • November 3, 2016

Lyrica (pregabalin) "Two attempts at treatment for fibromyalgia with Lyrica. Both had similar outcomes, in that the "cure" was worse than the illness. Side effects were overwhelming from the onset: increased fatigue, terrifying anxiety, tremors. In addition, this drug's efficacy was zero. I received no positive effects from Lyrica and discontinued use. Side note: I need to learn about illnesses that affect me and medications that I take or are offered to me. Doctors may mean well, but I need to know how they affect ME, not just what is printed in a package insert. And if a doc is not right for me, it's time to find her replacement."

1 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • July 10, 2012

Lyrica (pregabalin) "I have only been diagnosed for about a year now. I have completely lost my life due to fibromyalgia pain. My doctor started me on Cymbalta, which worked for awhile but then stopped, then put me on Lyrica without weaning me off Cymbalta....WITHDRAWALS hello. Had to start again and wean off while also taking Lyrica. The Lyrica seemed to help at first too, then wham just like everything else, stopped working....EXCEPT on weight gain and brain fog. I was a zombie. So now I'm worsening day by day even though I try to stay active have cut all caffeine, etc. because my doctors just don't believe pain medicines help and say there isn't much else they can do for me. Glad for the people it has helped."

1 / 10
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  • Rosie
  • Taken for 6 months to 1 year
  • February 5, 2020

"I was on the pfizer Lyrica it helped control fibromyalgia CFS/ME pain and kept seizures under control as well. Around spring of 2019 I was switched to generic pregabalin by Amneal Pharma ITS GARBAGE! It doesn’t work and since starting it I can add severe kidney pain to the list. I'd encourage readers to complain directly to them thru their website or email them"

1 / 10
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  • TMarie
  • June 4, 2016

Lyrica (pregabalin) "Lyrica has done a great job on my Fibro pain, but I am trying to get off it primarily due to side effects. It has caused mymetabolism to slow down so I can't lose weight, chronic constipation, and terrible gas. I can't go around anymore farting everywhere I go. I'll live with the Fibro pain."

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  • emily
  • Taken for 6 months to 1 year
  • August 20, 2015

Lyrica (pregabalin) "Lyrica did not work particularly well for me. I had previously taken Cymbalta 60mg for 7/8 years and was feeling that it was no longer as effective so my doctor prescribed Lyrica. I noticed a large amount of weight gain (which I would not have minded if helped the pain!) about 50 pounds over 6 months before it stabilized. After some time of taking the medication (9 months or a year I forget) I was always complaining to my doctor about pain and fatigue being bad so he switched me to Savella. I noticed a huge difference and I lost the weight!"

2 / 10
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  • cat_b...
  • Taken for 1 to 2 years
  • January 26, 2013

Lyrica (pregabalin) "I started taking this at 150mg twice a day with some relief of pain, no side effects. I've recently increased to 225mg twice a day, which is the maximum dosage. I'm experiencing vertigo, sleepiness, and weight gain, but virtually no pain. My doctor feels the results out-weigh the side-effects and I agree."

9 / 10
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  • fibro...
  • Taken for 2 to 5 years
  • September 7, 2012

Lyrica (pregabalin) "Can't live without this! Lyrica is amazing. Had one doctor add in gabapentin to my cocktail and it helped some, so he put me solely on gabapentin and off the lyrica. It didn't take long before my pain levels started to spike. Now I am back on Lyrica 100mg 2xday and I am so much better!"

10 / 10
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  • Sherry...
  • April 18, 2017

Lyrica (pregabalin) "Been on this Lyrica 200mg for @ least 2 yrs I still have a lot of pain from having the disease of Fibromyalgia & Chronic pain along with arthritis they raised it up to the highest dose & still hurt very much & I agree with the lady above u do gain weight trying to hang in there! Hope they find something better for me & every one else Blessings to all "

5 / 10
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39 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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