Skip to main content

User Reviews for Perphenazine to treat Psychosis

Perphenazine has an average rating of 5.7 out of 10 from a total of 15 ratings for the treatment of Psychosis. 53% of reviewers reported a positive effect, while 33% reported a negative effect.

Perphenazine Rating Summary

5.7/10 average rating

15 ratings from 16 user reviews.

Compare all 11 medications used in the treatment of Psychosis.

10
13%
9
13%
8
27%
7
0%
6
7%
5
0%
4
7%
3
0%
2
0%
1
33%

Reviews for Perphenazine

Anonymous May 23, 2011

Trilafon (perphenazine): “I had a similar experience. Tremors in hands (not really noticeable to someone watching unless they were looking for it), but relief from the delusions I was experiencing. My problem has been going on for over 16 years so I anticipate it will not magically disappear (and it didn't) but the clarity of thinking I experience with this medicine really helps me.”

9 / 10
Was this helpful?YesNo
Eric8428 · Taken for 2 to 5 years December 21, 2012

“I have been on Trilafon (perphenazine) for about 4 years. I'm on a low does, 4mg x3 times a day. From what I understand this medicine is a lot more gentle than most medicines that would treat bipolar, schizophrenia, and other forms of psychosis. Its not good for elderly as the higher the dosage you get the more at risk you are for tardiv dyskinesia (or tremors of the face, arms, and hands). I am 28 and this medicine worked when Lexapro, Geodon, Haldol, and risperidone wouldn't. I am given it for Pscyhsis. In addition I am on 40 mg Viibryd and 0.5mg of Klonopin. I would recommend this medicine. ”

8 / 10
Was this helpful?YesNo
YelllowWingz · Taken for 6 months to 1 year January 13, 2019

Trilafon (perphenazine): “I was prescribed this in 2014 when I was 13 years old. It gave me permanent side effects. They include, WIDENED WAIST that I cannot shrink, weird movements with my face I have to do patterns in every single part of my body, it made me eyes look opposite ways which now in 2019, is still there but not as bad. It made me gain weight, it made my skin dull and grey like I was dead. I wish I could include a picture. It made me have a permanent tremor, too. It's a horrible drug. My posture now sucks and I can't breathe if I try to fix it. I can no longer tan after I took it. I was tan my whole life now my natural tanning peels off and I am white I was never white”

1 / 10
Was this helpful?YesNo
MomV. December 8, 2015

“My son has been hospitalized 4 times in the past 5 years.The doctors have prescribed a myriad of of concoctions over these years. I've seen my son go from a healthy 160 teenager to a 210 lb unhealthy sluggish overmedicated sad shell of a person. When he was introduced to perphenazine he seemed to come back to life. But,unfortunately as soon as we see real results he quits taking the pills and it all starts all over again. How can I get my son to stick to taking his medication?Any suggestions??”

6 / 10
Was this helpful?YesNo
Disappointed badly November 3, 2016

Trilafon (perphenazine): “I had a very bad experience with perphenazine. I ended up with severe joint pain, difficulty breathing, chest pain, weird spinning sensation in my face on the right side of my nostril, on my forehead and on the right side of my temporal area. I had difficulty urinating and horrible insomnia. It has been well over 6 months since taking up to 12 mg for only a few ( about 2--4 days) and I am still having problems. I started on only 4 mg back in Dec 2013 and took the same dosage up to Mar 2014. I stopped because I could barely urinate. Then, I started have weird movement as stated above in my face, but not as bad as the movement when I took 12mg. The, I was told that I needed to start back on this drug for the movement to disappear.”

1 / 10
Was this helpful?YesNo
brain100 · Taken for 1 to 6 months April 7, 2019

“My sibling was taking this drug, at first it seemed to make her better she would complain of difficulty swallowing and neck stiffness and constipation. After 3 months , she went into delirious state overnight and complained of headache, she was hospitalized in catatonic state, has a MRI and CT scan which revealed fluid build up. All medical tests to find cause of fluid build up came negative. This drug side effect is cerebral edema (fluid buildup) and NMS (neuroleptic malignant syndrome). The fluid build up only becomes clear during CT scan.”

1 / 10
Was this helpful?YesNo
rita · Taken for 1 to 2 years October 26, 2018

“I have been on medicine from 2016-2018, gained 30-40 pounds. Sometimes it is hard do to anything and I can not focus very well. In the last 4 months, I am having to shuffle my feet and feel like I might fall over. Wish to find other medicine doctor can give me.”

4 / 10
Was this helpful?YesNo
trrer · Taken for 6 months to 1 year January 3, 2018

Trilafon (perphenazine): “This really helped my PTSD and major depressive symptoms. Much better than seroquel. Movement side effects when I got up to 12 mg a day. Lowered my dose back down to 8mg a day and the movement side effects went away.”

Was this helpful?YesNo
Ivanisgreat · Taken for 1 to 6 months September 20, 2018

“This medication is very good for anxiety. It worked wonders for my anxiety and paranoia. Helps lower the voice in my head telling me people are out to get me. Zyprexa works well too but I have problems with my memory. It’s hard to deal with and I am wondering how I can deal with the anticholinergic effects from these medications. Any suggestions?”

8 / 10
Was this helpful?YesNo
JabbertheHut888 · Taken for 1 to 6 months October 13, 2016

“It was an OK experience for me! I don't think I hit the full effects of it just yet...but Paxil @40mg seems to work much better for me. Tired of trying meds that don't make me too sleepy as well. Also, my appetite was low so I lost a few extra pounds. If I don't see results in another 4 weeks, I'll ask my doctor to put me on Rexulti.”

8 / 10
Was this helpful?YesNo
Jonny longlegs · Taken for 1 to 6 months February 14, 2017

Trilafon (perphenazine): “I was put on this drug, erroneously I believe as I was only suffering a major depressive episode, in 1974. From that time until I went through menopause in 1997 (23 years) I had the side effect galactorrhea. I was never pregnant or post breastfeeding during that time and took no other medication with that side effect.”

1 / 10
Was this helpful?YesNo
BK October 8, 2020

“I was put on this drug perphenazine when my Psychosis got 'a little' out of hand after other medications failed. I experienced a very rapid recovery while on Peratsin (perphenazine) and did not need a long-term therapy on the drug. I start the drug occasionally when rapid thoughts and feeling of mania/psychosis start to appear, always helping to resolve and stabilize me. It worked wonders for me but I do know the dangers of the drug, like developing tardive dyskinesia which scares me.”

8 / 10
Was this helpful?YesNo
Kelli · Taken for 6 months to 1 year December 5, 2020

“I loved perphenazine except for the movement side effects but Valium helps that. I was recently put on haldol and had a psychotic break so my doc put me back on perphenazine. It helped lower and tame my voices. It’s a wonder med don’t rule out the old meds completely they work. This is someone with schizoaffective disorder.”

10 / 10
Was this helpful?YesNo
GTTDD45634555 · Taken for 1 to 6 months October 18, 2016

Trilafon (perphenazine): “Not bad! I'm taking other meds as well. I recommend everyone gives it a chance before judging to harshly on this site.”

10 / 10
Was this helpful?YesNo
JabberDHUY99909 · Taken for 1 to 6 months October 26, 2016

“Not that bad! Daytime drowsiness.”

9 / 10
Was this helpful?YesNo
Gabs · Taken for 1 to 6 months August 25, 2020

“This drug perphenazine made my psychosis SO much worse. ”

1 / 10
Was this helpful?YesNo

This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.