Perphenazine for Bipolar Disorder User Reviews

• REd...
• January 17, 2016

"I was very hot-headed with sudden rage or seething anger all of my life until I got on Perphenazine. This is an amazing drug. I NEVER get angry now. I did get angry once at something which I believe is justified, but I didn't feel deep rage inside. It went away. I have been on Perphenazine for a year or so now, and I feel like a totally different person. It did take a little while, maybe a few months (I'm not sure) to take effect. I was psychotic when I first began taking it (delusional). It is an amazing drug. Also, I can think more clearly and think 'better,' which is hard to describe. I can solve problems more easily, analyze situations, and it feels as if my 'engine turned over' (brain) and I am smarter now, much smarter. Amazing!"

• Sam...
• February 23, 2012

"I was on a very high dose (64 mg/day) for two years. At first, it was wonderful. My Dr. told me it was a mood stabilizer, and for me, it did just that. For a while. After a few months, I started taking naps in the day - HIGHLY abnormal to me. Then, after the naps, I started to go to bed earlier and earlier. Then one day, I realized I was sleeping 17 hours out of the day! Since I followed my Dr.'s instruction, and weaned myself off, my days are bright again! No naps, chores are getting done, I am not neglecting my hygiene, picking up forgotten hobbies, living, THRIVING! And absolutely no withdrawal."

• Anonymous
• July 26, 2011

Perphenazine "I have been on Trilafon for 2 years now. Mostly, I liked it at first because it brought me back to earth when I was over-anxious. I have lowered my dosage since then, and I thought it was doing me well, but I have been having neck problems lately and have realized that this is a side effect of Trilafon called extra-pyramidal syndrome that damages my posture area, so no matter how hard I try, I can't regain a good posture."

• bra...
• Taken for 5 to 10 years
• July 25, 2013

"Have been bipolar all my life and have major anger issues. Since my doctor put me on perphenazine (4 mg daily), my issues have dramatically decreased, but still flare up now and then. The only side effect I found is the lethargy after taking it."

• Tra...
• Taken for 1 to 6 months
• March 25, 2018

"I just started this medicine again because I tried to tough it out again with just sleeping pills. I hated Seroquel. I want to be able to move and not gain so much weight. I know now it's impossible. I feel worse or take the consequences. I have bipolar disorder with psychosis, PTSD, and severe depressive disorder with panic attacks, agoraphobia. I act on an impulse, it goes on and on. I'd just like to see if you people had any luck. I'm tired of bad meds. I'm 43 and still praying."

• A...
• November 2, 2021

"When loxapine was discontinued, I was put on perphenazine. I have to say this is a true miracle drug for me. Not only do I have rapid cycling bipolar I, but also generalized anxiety disorder and panic disorder. This drug has greatly helped with all three. I have less anxiety and panic attacks, and my manic episodes are better controlled. Of course, I still have all these things, and it has gotten worse as I get older, this drug helps. The only thing I have noticed is some sexual side effects if my dose is too high and a more pronounced occurrence of my tardive dyskinesia, which I unfortunately have some permanently from taking Haldol for too many years. But there are good meds to control that as well. Try it if you respond better to older meds, especially if you have anxiety too. You won't be disappointed! I take 8 mg a day. A low dose, I realize, but any higher, and I have the above issues. And I have other drugs to control my illnesses as well."

• Kin...
• Taken for 1 to 6 months
• June 24, 2022

"This has been a wonder drug for my bipolar disorder. I’ve been prescribed it many times over the years, and it always evened out my mood, gave clarity to my thinking, and helped me stay motivated and focused, whereas I usually become overwhelmed and disorganized. Various doctors have taken me off it in fear of side effects I’ve never had. I’m now in my 50s and grateful to be back on it at last!"

• fun...
• Taken for 10 years or more
• September 3, 2018

"I was taking perphenazine for about 20 years. When I first started taking it (4 mg), I had good results. I had anger problems that greatly improved. However, I switched doctors, and my dosage was increased to 40 mg. I started getting uncontrolled eye movements. I was given a medication to counteract it. I was on that dosage for many years, spending the majority of my time sleeping. Four years ago, I decided to take a part-time job and slowly stopped taking it. Since then, I have had numerous stomach problems, including gastroparesis. I don't think the long-term side effects were worth it."

• Jud...
• Taken for 6 months to 1 year
• April 24, 2014

Perphenazine "Helped stop hallucinations."

• Anonymous
• April 7, 2011

"This has been helpful with the anxiety and mood swings. Doesn't seem to have as much of an antidepressant effect as Abilify did for me."

• Anonymous
• Taken for 5 to 10 years
• November 12, 2012

"Keeps the crazies at bay (mostly) - the delusions, etc."

• jan...
• Taken for 1 to 6 months
• August 6, 2021

"This med does wonders for my focus and anxiety. All my anxiety has disappeared. It's made me a little drowsy, but I am starting a stimulant med to combat this."

• Wob...
• Taken for 5 to 10 years
• September 20, 2023

"Very good. Only antipsychotic I can take. Not sleepyhead. No side effects. Old faithful, I recommend."