User Reviews for Ibrance to treat Breast Cancer, Metastatic
Ibrance has an average rating of 6.6 out of 10 from a total of 49 ratings for the treatment of Breast Cancer, Metastatic. 61% of reviewers reported a positive effect, while 31% reported a negative effect.
“Found out I had metastasized breast cancer in September 2018. Started my Ibrance treatment along with tamoxifen October 2018. I had a tumor in my right breast 2cm. With the cancer spreading to my Right (armpit four small tumor ) and a pea size tumor in my throat area. I just had my PET scan this month April 2019. The tumor in my right breast is almost gone. I only have one area under my armpit showing signs of cancer not four. And the one that is in my throat is only half the size it was before. The medication is working!!!!! Praise god. When I first started taking it food tasted weird but now everything is fine. You may be a little tired but you will get energy eventually stay busy stay focus. Please stay positive ”
“I was Diagnosed 9/2017 Stage 4 Metastatic Invasive Ductal Carcinoma E+/P+ HER2- (spread to my adrenal glands, lymph nodes and Bones:spine, tailbone, sciatica, sacrum, ankles, wrists, & neck) Did 10 rounds radiation and lots of Chemo. Radiation made my port go septic and gave me radiation pneumonitis putting me in the hospital for 17 days...I thought this was it, I was going down. The Chemo is really hard to go through. All us warriors know that. Tons of effects. Then I went on IBRANCE...Had to adjust my dosage from 125mg to 100mg because of going neutropenia. The 100mg seems to be working. I am so thankful! I had PET SCANS before treatment and just did another after a year and one month of Radiation, Chemo, and now Ibrance taken with letrozole I am in Remission!”
“Diagnosed Stage 4 breast cancer invasive ductal hormone receptor positive HER2 negative metastatic to bone in 2016. After mastectomy/ lymphodectomy was treated with radiation and hormone treatment. Tamoxifen, letrozole had side effects did very well on anastrazole until scan in spring 2019 suggested more cancer in lymphatic system. Started Ibrance 21 day on 7 off and fulvestrant monthly. No obvious cancer after 6 months and now a year!! No cancer!!! Some side effects but definitely mild.”
“I began taking Ibrance, Faslodex and Zometa in Febraury 2019. Since then I have had three CT Scans. The CT Scans have shown marked reduction. I have had few side effects if any. This drug was designed to give cancer patients like me more time. I am privately insured. The Pfizer program pays for my out of pocket cost each month.”
“I was diagnosed in 1991 with Inflammatory Beast Cancer with the tumor the size of a grapefruit. Chemo, Radiation, Chemo; told I would soon die. Miraculously survived. 26 years later I was diagnosed with 13 breast cancer tumors in spine, uterus, chest, by skull. Radiation, Ibrance. 2 months ago my PET scan showed all 13 have disappeared. No side effects (that I know of) from Ibrance except for an awful taste in my mouth. Just awful. Thankful to be alive but wish I could taste just one thing normally again. I'm frustrated. Only thing that tastes "not bad" is ice cream.”
“Diagnosed breast cancer 1/28/16 metastatic, spine and ilia crest, 3/14/16. Started Ibrance/Letrozole in April. After 24 cycles I am NEAD and original tumor is not showing on PET scans. Recently talked to a woman that was starting cycle 37 so I am extremely optimistic for the future. Side effects are manageable. Wish everyone was this lucky.”
“I was prompted to write this after reading some of the negative reviews. God how I wish this would work for everyone. I have only been on it for around 7 months but my first scan was promising (I have bone metastasis and there were no new spots and previous lesions appeared smaller). I go for my next scan in a few weeks. I'm so fortunate in that I've had no side effects. Your neutrophils will dip and yes, I'm tired at times but what else is new. I know that some are experiencing terrible side effects but I wanted to chime in and say that not everyone experiences them. I do take spirulina pills and they seem to help get my neutrophils where they should be (above 1.0). If you are a candidate for ibrance, count yourself lucky and try it!”
Frequently asked questions
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“I'm on Faslodex and Ibrance. My cancer was in my lymph nodes near my clavicle, on T10, T11, T12, L5, on my Sacrum and spread around my pelvis in a lot of little spots, plus it was in my hip joint. My organs were spared, but it was scary since it was in my lymph nodes. I've been on Faslodex since August 2016 and I started Ibrance in September 2016. In just two months, all of my lesions have shrunk and there's no new metabolic activity surrounding what remains. I take my Ibrance at night and don't feel dizzy or nauseous. I don't feel too great if I eat too much, but as long as I eat light meals, my energy is good and I feel normal. I do feel fatigued from time to time, but a quick nap leaves me feeling refreshed.”
“I was originally diagnosed in the fall of 2003 with Stage 4 Metastatic Breast cancer (hormone receptive) that was also evident in my liver. My new "Doc" prescribed chemo & radiation after which I was prescribed Arimidex which lasted for 11 years (I elected to not have surgery to remove the culprit breast). Then, a small suspicious lesion appeared on said breast that, when biopsied, was diagnosed as positive non hormone receptive & my Doc recommended removal. Shortly after surgery, my Doc retired. Results were not good afterwards but, after finding a new Doc quite some time later, he prescribed Exemestane &, later, Ibrance. Over a year after adding Ibrance, I feel great with minimal side affects & good numbers. Just wish I could qualify for financial assistance (self employed & all assistance I've found so far only considers gross income, not net, :-( , totally not fair).”
“I had breast cancer 24 years ago. Was treated with chemo and radiation. Earlier this year Doctors discovered that I had metastatic cancer. A nine inch cancer between the lung and rib cage. Side effects of Ibrance were a little rough at first but eased up as time went by. Stomach problems, headaches, weakness but they eased up as time went by. I learned that I had to drink lots of water. It is now 8 months later and My cancer is in remission.”
“Diagnosed MBC February 2014! In breast and sacrum. Started femara only, no progression till October 2015! Spread to two ribs and spine. Started ibrance with femara and scans got better and better until 2 months ago, scan showed no hot spots!! As far as I'm concerned, in remission!!! Side effects, hair loss, no taste, tired all the time, severe hot flashes, shortness of breath, joint pain, but I can live will it all!! Thank you pfizer and everyone involved in the studies who lived and died so I may live longer!”
“My mom has been on ibrance for over a year now. She had breast cancer in 2004, came back in 2010, then came back last year at the beginning of 2016 and had spread to her bones and skull. The medication has been wonderful. Definitely side effects but that is expected. Overall there has been little, if any, growth of the cancer. We had no idea how long it would be effective but we are going on 15 months now and she just got head MRI results today and still looks good. She will get pet scan in June or July to assess full body but we are so fortunate. This medication truly has bought us so much extra time with her. I pray everyone has positive effects with the medication. Stay strong and hopeful. There are always new treatments on the horizon.”
“I have been taking ibrance/letrozole since 2017 for breast cancer mets, with great results. No new growth! Recently the ibrance capsules were changed to a tablet. The new tablet comes in 3 cards of blister packs per month. The tablet is easy to swallow, as was the capsule. However, the blister packs that it comes in are very difficult to open, especially for those of us with arthritis or who are weak. I was told not to open the packs early to load my pill case due to the stability of the tablet. We have enough problems without having to struggle to get a pill out of a pack every day. Perhaps the company could change back to the capsules in a bottle or reinvent the tablet so it can be in a bottle. Thank you”
“My mom had breast cancer which had spread to her bones, chest lymph nodes, lung, and liver (7x6cm), and we tried every drug in the market for the last year. Nothing worked for us, and the tumor kept growing out of control. We were so desperate for any slim of hope until she started Ibrance with Fulvestrant. Her first blood draw after being on the medication for two weeks showed that her neutrophils counts were to low so she stopped for 2 weeks. She restated at a lower dose and had a CT scan (because she has new symptoms so her Doctor ordered a scan). The results were extremely promising as there's been no new development and all tumors were shrunk by at least 50%. I am hoping it will continue to work for her.”
“I am dying. Ibrance worked for about 12 months. All my good blood cells have died and left my immune system defenceless. I wanted to live longer. In the end this harsh drug has rendered me defenceless.”
“I have hormones receptor positive and HER2 gene negative stage 4 breast cancer and started ibrance February 2020. So far, I really like how it is working for me. When I first started my WBC dropped very low but then my oncologist switched me to the lower dose and my WBC does a lot better. At my last appointment in June 2020 my cancer markers have dropped a lot since February and my breast cancer has even shrunk quit a bit. I am very happy with this medication. I also take fulvestrant once a month.”
“I went on it for one cycle with letrozole. Immediately I felt so awful like I had been poisoned. All my lab work became really horrible. I was so weak and sick I could barely move. I had to skip many doses because I was so sick. And then found out the cancer progressed crazy fast in the less than three weeks on it. It took me many months to recover. I feel like I have PTSD from being on that drug. And with the side effects being so horrendous I stopped the letrozole during the first week because the hormonal side effects on top of the toxic poisoned feelings on Ibrance weren't helping things at all. So far I've done about a dozen metastatic breast cancer treatments since diagnosis in 2011, and that was the scariest and most dangerous treatment ever. We need some real treatments that aren't destroying people. My mom's friend died during her first cycle of Ibrance from organ failure. They're still trying to figure out what happened.”
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“My oncologist put me on Ibrance since last week of October 2015. My treatment also includes Faslodex and Lupron. My cancer metastasized on the lining of my lungs and also the pelvis area, right breast, and ovaries. Lungs collapsed. Was prescribed oxygen on exertion. First few weeks on Ibrance, I was getting worst but by 2nd week of December, cancer damage started reversing. tumor disappeared, lung fluid decreased, SPO2 got normal. In April 2016, PetScan says that cancer is no longer detectable... latest PetScan in July says the same plus no more pleural effusion. I didn't have any side effects at all. I am still on this treatment: Ibrance + Lupron (every 3 months) + Faslodex (every month). I am ER-, Her2-, and PR+.”
“The wife is battling from Stage 4 Metastic Breast cancer. Doc put her on Ibrance and Faslodex after chemo was no longer effective August of 2017. It made things worse so that by September she was bed ridden and she passed away 11/29/17. Now I have read articles that this miracle drug from Pfizer was no more effective than a placebo after a year on the market. Shame on you Pfizer for putting a drug out there under false pretences and makes one wonder if your highly touted controlled testing was not factual to sell an over priced underperforming drug.”
“I was diagnosed with stage IV breast cancer in February 2015. Ten lymph nodes tested positive and it had matastized to my bones. I started taking Ibrance and Lotrozole in April 2015. I have no notable side effects other then after being on it for 14 months it started destroying my hair and my blood counts is always low. My scans have all been good. Up until last week I still worked full time, but now that I am 65 I think it is time to go part time. I guess the fact that it isn't curable and the unknown is my worst fear. Good luck to all.”
“Diagnose with Mets to lung and bones. Aggressive chemo worked for eight months and then I was moved to Femara and Ibrance. Had to pay for the drug out of pocket because I'm not insured and cost us a king's ransom. This money could and should have been better spent. Ibrance wiped out my immune system and spread my cancer. After two months I complained about breathlessness but my oncologist assumed that we should give it some more time to work because of the promotional reviews and propaganda by Pfizer. I hate how pharma industry is devouring our savings. They should not overrate their products and misguide oncologists. I don't know how they report results. I doubt that I will ever be counted among the failed cases. Very angry & disappointed.”
“I was diagnosed with Stage 2 Breast Cancer in 2010. Then Stage 4 in December 2015. Mets to spine, T-1 at first then & L-1 recently. Taking Ibrance, Faslodex & Xgeva. Overall feeling pretty good & side effects are not bad. PET scans are good & blood work is good as well. Feeling lucky so far but the unknown is very scary! Pzifer has a 10.00 copay plan on their website for anyone taking this drug.”
“I am still in treatment, but my initial impression of Ibrance is positive. My doctor is extremely supportive of it's uses and anticipated outcomes. (I have a fantastic doctor) I've had ease of access, when I mention Ibrance to medical professionals and the like their response is positive according to what they're hearing. My side effects have been few and not severe. The only major reaction I experienced was during the course of undergoing radiation treatments and taking Ibrance & Femara in combination. I became neutropenic (sp?) w/mild diarrhea, weakness, dehydration and throat and esophagus challenges. My challenges were a bit overwhelming. The newness of Ibrance concerns me. Just hoping it does the job! Thank you.”
“The first time I tried this my tumor shrunk by half in 3 months. I had to stop due to the extreme side effects. Just restarted at a lower dose and there are still some wicked side effects. However with the results I've had I'll tough it out and keep hoping for the best.”
“I was diagnosed with Stage 1A Breast Cancer in July 2019. I started on Tamoxifen in October 2019. In April 2020 my tumor marker shot up so Bone and CT scan were done, results not good so a biopsy was done on lower spine and May 5, 2020 found out that the cancer had metastasized to my bones. June 2020 started Faslodex Injections, July 2020 started Ibrance capsules and Xgeva injections. PET scan in September and December 2020 showed no progression or activity and CT in April 2021 shows no progression or activity. I am thankful that this treatment regimen is working. I get fatigued easily and my bones hurt (but that is from the Xgeva) but no other problems being on the medications.”
This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.
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