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Oxymorphone and Irritability: What Users Say

Irritability: mentioned by 5 users (2.3%)

Based on user experiences from 216 Oxymorphone reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 4.2%
withdrawal 4.2%
constipation 2.8%
drowsiness 2.3%
headaches 2.3%
irritability 2.3%
pain 2.3%
vomiting 2.3%
anxiety 1.9%
depression 1.9%

Reviews for Oxymorphone

Showing 5 reviews tagged with "irritability". Clear filters to view all 216 reviews.
Commonly mentioned side effects
  • Pro...
  • Taken for less than 1 month
  • February 15, 2016

Oxymorphone for Pain "Opana 20 mg doesn't take away all the neck and back pain but does about 90%, so I can function. However, also for the first time in my life, it gives me headaches, hot flashes, warm blooded 4-5 of 7 days a week, and slightly edgy/difficulty with stress/adversity sometimes too."

7 / 10
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23 Report
  • Two...
  • Taken for less than 1 month
  • November 11, 2012

Oxymorphone for Pain "I took one dose of 20 mg of Opana ER. I became dizzy, woozy, lightheaded. I developed a pounding headache! I became extremely agitated and anxious. I became very shaky. My lower back pain increased, not decreased. Seven hours after taking this one dose, I had projectile vomiting."

1 / 10
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52 Report
  • sue...
  • January 3, 2011

Oxymorphone for Pain "Seems to be working okay. The buzz is calming after taking for 2 weeks. I'll not take the morning dose if I have to function during the day. Does help with chronic back/cervical/knee pain. Side effects are easier than morphine. That made me irritable and didn't touch the pain."

9 / 10
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24 Report

Frequently asked questions

  • jus...
  • April 13, 2017

For Pain "I have spinal stenosis, DDD, bone spurs, ruptured discs, double laminectomy at L5-S1, L3-L4 in 2013. I've been on oxycodone for over 4 years. That worked great, but I started at 100 mg a day and even now only at 80 mg a day, so I think it is not out of the ordinary to have a built-up tolerance. Dr. switched from four 20 mg oxycodone to four 10 mg oxymorphone. He said it is equivalent to 25 mg oxycodone. It worked a little better on pain, but the side effects were awful! I was very sedated, moody, irritable, and grumpy. The worst was at night, I had a restless leg syndrome type of pain in my legs, and I could NOT stay asleep, even with sleep meds! I do NOT recommend this medication! I'm looking into this genetic test I keep hearing about!"

1 / 10
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10 Report
  • jus...
  • April 13, 2017

For Pain "I have spinal stenosis, DDD, bone spurs, ruptured discs, double laminectomy at L5-S1, L3-L4 in 2013. I've been on oxycodone for over 4 years. That worked great, but I started at 100 mg a day and even now only at 80 mg a day, so I think it is not out of the ordinary to have a built-up tolerance. Dr. switched from four 20 mg oxycodone to four 10 mg oxymorphone. He said it is equivalent to 25 mg oxycodone. It worked a little better on pain, but the side effects were awful! I was very sedated, moody, irritable, and grumpy. The worst was at night, I had a restless leg syndrome type of pain in my legs, and I could NOT stay asleep, even with sleep meds! I do NOT recommend this medication! I'm looking into this genetic test I keep hearing about!"

1 / 10
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10 Report

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