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Misoprostol and Pain: What Users Say (Page 2)

Brand names: Cytotec

Reviews for Misoprostol

Commonly mentioned side effects
  • Mir...
  • May 19, 2020

For Abortion "In the 7th week of my pregnancy, it turned out that the embryo did not have a heartbeat. I was informed about my options: 1) natural miscarriage, 2) pills, 3) operation. I consulted with 3 different doctors, and they all recommended option 2, the pills. I placed 4 pills in my vagina, and after 3 to 4 hours, it started. I had diarrhea, I felt really sick, the pain kicked in without any transition. I wanted to take some pain relievers, but that was too late. When I swallowed them, I started to vomit immediately. I was pooping and vomiting, it felt like my body wanted to reject everything. The pain was non-stop for an hour and very heavy. It must have been similar to delivering a baby. In the second hour, I noticed cycles: 2 minutes of pain, 2 minutes of pause, and after 2 hours of agony, the pain started to be less. After a total of 2.5 hours, it was over, and I guess I was lucky. The blood came only after 2.5 hours, a bit more than usual. I bet if I were waiting for nature to solve it, it would have been less painful."

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  • Anonymous
  • Taken for less than 1 month
  • October 4, 2021

For Cervical Ripening "By far the worst experience of my life. Inserted 4 pills vaginally. About 15 min after, I already felt a little cramping. I thought, OK, I guess this is what happens. Little did I know I was about to go through the most horrific pain ever. As the 'cramping' intensified, I began to feel cold, I was shivering, teeth chattering, and all underneath a blanket. This lasted about over an hour, meanwhile, the cramps were becoming unbearable. I went to the bathroom, had streaming diarrhea, and a while later began projectile vomiting, barely making it to the bathroom in time. The intensity of the cramping was so severe that I cried out for God, hoping this pain would lessen or end. But it didn't. I called the doctor, and they said this happens sometimes and to take the pills out. Unfortunately, I was only able to get two out while urinating. The horrific pain continued as I writhed in agony and torture. 4 days later and still battling severe body aches, weakness, pain on my side, targeted cramping, fevers."

1 / 10
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  • Anonymous
  • August 28, 2021

For Abortion "I just wanted to leave a review here and let you guys all know how my experience went! ….. I am one of the most anxious persons ever! I suffer from anxiety also, so just know I was nervous about the whole process and scared reading some of these reviews. TRUST ME, it’s NOT scary at all. Took the first pill Thursday at 12:30 pm, nothing at all. 2nd pills, which was 4, I did vaginally. 24 hours later, which was 12:30 pm Friday, but I did take ibuprofen 20 minutes before, just 400 mg. About an hour and a half after that, I was bleeding and had blood clots, but no pain at all. I had about 3 clots within 3 hours. Guys, this is not scary at all, and if I made it then you can. We are strong, independent women, so please don’t think that you can’t do it because you can! Sending love to all women that have to go through these tough times."

10 / 10
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Frequently asked questions

  • Meg...
  • January 31, 2020

For Abortion "My experience with abortion pills was quite easy. I took the first tablet at the clinic, second four hours later as I was only 5 weeks pregnant. Started to bleed after one and a half hours slightly, and heavy bleeding started after three hours. It started to become very painful, but the pain has stopped after 2x codeine tablets that the doctor prescribed. I bled through two sanitary pads as well as sitting on a toilet. Heavy bleeding continued for a couple of hours. I woke up the next morning like nothing happened. Would strongly advise taking pain relievers for those who cannot tolerate the pain. Overall, it wasn’t a pleasant experience, and hopefully, I will not have to go through this again."

8 / 10
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  • Dar...
  • Taken for less than 1 month
  • July 10, 2019

For Abortion "I just wanted to write a review from my good experience because I worked myself up silly after reading awful reviews on here as I have a huge phobia of sickness, etc. The first tablet did make me sick, but this tablet was great. I did get cramps, and yes, they are more painful than periods, but that was about it. You will pass pretty big clots and bleed heavily, so stock up on extra thick pads, but from my experience, I am very happy. Don't believe everything you read on the internet, some of it is the placebo effect from working yourself up. Insert vaginally if you want. TRY and avoid the side effects (not saying it will eliminate as everyone is different), but yeah, the bad pains for me didn't last more than 5 hours. It's not pleasant (obviously), but not godawful either. Good luck!"

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  • Jum...
  • Taken for less than 1 month
  • November 17, 2019

For Abortion "I’m 7 weeks pregnant, and I started the second dose at home on Saturday at 12. I immediately started feeling cramps within that hour, and the cramps started heavily kicking in, but it felt like my normal period cramps, but 10x worse. I was given ibuprofen 800 mg every 4 hrs. The pain lasted 'til after midnight. I honestly thought it was supposed to past 4-6 hrs, so I was watching movies to pass time. It was painful but bearable. I bled the first 4-5 hrs, but I didn’t see any tissue come through, it felt like my normal heavy period. I’m honestly a little scared I might have to take it again, but the overall experience was painful but bearable. But like the doctor told me, every woman’s body is different. Just make sure you take pain meds and get rest... watch movies to keep your mind off of it. Go to the follow-up appointments. I didn’t get any of the other symptoms of vomiting or diarrhea. I hope this helps."

8 / 10
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  • Man...
  • Taken for less than 1 month
  • December 31, 2020

For Abortion "I took 1 pill at the clinic, 4 pills the next day. The pain started within seconds once I swallowed the medicine. Worst cramps ever! I did take ibuprofen and anti-nausea medication. But I still suffered pain. I wasn’t able to sleep because the pain was so bad. 8 hours later, blood clots are still coming out, and I’m still getting cramps, but they aren’t as bad as they were in the very beginning. My opinion: if you do not have a good tolerance for pain, do not take these. I was very sad due to the circumstances, but I’m glad I’m almost over this pain already. Good luck, ladies."

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  • Feb...
  • Taken for less than 1 month
  • February 20, 2022

For Abortion "I was around 4-5 weeks pregnant. I was prepared for the worst, but it was not that bad. I was instructed to take all 4 tablets vaginally. Cramping began within 15 minutes, but I didn’t start bleeding for about 5 hours. The pain was about a 5/10 in my opinion. I took the pain reliever dosage I was prescribed, but I did not take the Gravol I was given. I only needed two rounds of pain relievers overall. The real lifesaver was my heating pad. Bleeding was heavy, about twice as heavy as my period on its worst day (I used an overnight maxi pad for the first time in my life). But it subsided the next morning, and currently, I am on day two, and only very light bleeding at this point. I am so relieved this is done with and glad I did the medical route rather than surgery. Just be prepared with any supplies you need (pain relievers, heating pad, maxi pads) and a good TV show, and you will be okay."

10 / 10
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  • Too...
  • Taken for less than 1 month
  • May 27, 2021

For Abortion "It's been a week since I terminated the pregnancy. However, I took the misoprostol vaginally, all 4 pills at one time. About 5 hours later, I passed the pregnancy and lots of clots. Day 4-6 was the worst pain of my life. I'm certain I passed everything, but these cramps were sharp and painful, putting me in tears. Today marks day 7, I'm still bleeding moderately, but not much pain as well as light clots.... I hope bleeding stops for me soon. Besides that, fine."

8 / 10
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  • Mar...
  • November 13, 2019

For Abortion "Everyone is different. Mine cramps felt like regular period cramps, they gave me hydrocodone for pain, and I think it really helped. Take an hour before so it is working before you need it, and don’t be scared by all these other comments because they had me terrified, TBH. It was very easy and quick."

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  • Ano...
  • Taken for less than 1 month
  • November 6, 2023

For Abortion "I was 7 weeks pregnant. In the evening around 6:30, I took ibuprofen and the tramadol for pain that I was given. Then, about 7:15 pm, I put the 4 pills in my cheeks (2 on each side). I was absolutely terrified after reading some of the bad reviews. After waiting the recommended one hour for the pills to dissolve, they had only dissolved about halfway, so I drank some water and swallowed them. Around 9:00, I still didn’t feel anything happening, so I went to use the restroom to pee before laying back down. While sitting on the toilet, some blood came out, and several clots came out, followed by what felt like a few ping pong balls. I laid back down for about an hour and then got up again and passed some more clots and balls of tissue. After this, I slept a few hours, and the bleeding darkened and, by the next day, had slowed down a bit. I’m not sure if the pain meds helped that much or I just got lucky, but I had no cramping at all the entire time. It was similar to an extremely heavy period."

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  • San...
  • Taken for less than 1 month
  • April 28, 2019

For Abortion "I never knew abortion pills existed until I found out I was pregnant at home after a month of no period. I have 2 children already and really was not ready to add any more at this time. I took the first pill in the office and the next 4 at home 24 hours later, which I had to dissolve in my cheeks, two on both sides of my mouth. The pain started 45 mins later. Very intense cramps, I took ibuprofen 2 hours before. 2 hours later, I passed 5 huge clots the size of lemons, as I was told. I cried a lot. After that, the pain eased and I started to bleed like a heavy period, I used a heat pad the whole time. I laid on my couch. Overall, this was an okay experience, but I would have rather had a nurse around. I would recommend it to someone, but have someone around to help and support you."

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  • Nen...
  • December 13, 2019

For Abortion "I have taken misoprostol, 4 tablets. As soon as I got home, I took them orally with water, and pain, diarrhea kicked in so quick. I was on the floor of my bathroom with hot flashes and felt like I was about to die. For me, it was the worst thing in my life. I had the most intense pain. I had to rush to the ER after 5 hours of pain and no relief. I had morphine to calm the pain down. Now I wish I would have gone there much earlier. I had already passed 2 clots only in my house but still yet have no clue if I have expelled everything. I hope everything has come out so I don't have to take these nasty pills. Literally, if I knew it was this painful, I would have just done a DNC. That's how horrible this experience was for me. I was literally in the worst pain on my bathroom floor."

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  • Ano...
  • January 9, 2021

For Abortion "I was so scared after reading these reviews, I didn’t sleep for days, but here’s what happened to me. Took 800 mg of ibuprofen and the codeine the doc gave me at 9:40, then 4 misoprostol at 10:40 am. Nothing happened until 2 pm! At that point, I’d just taken my second round of pain relievers. Pain was bad, like your worst ever period x 10, I’d say. Awful but bearable. Hot water bottle/heat pad is your BEST FRIEND. Helps so much, and keep on top of pain relief. Passing clots is the worst part for me. It feels weird, and your imagination kind of runs wild while it’s happening. Pain relief, hot water bottle, and someone there to help you through, and you’ll be absolutely fine, and I’m a WIMP, so that’s a lot coming from me."

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  • 324...
  • January 30, 2024

For Abortion "Ok, so I took the first pill at 6 pm. The next day, I took the next pill at 8 am. I couldn’t wait 24 hours because I was nervous. I laid in my bed, and around 11 am, I ran to the bathroom and sat on the toilet. That’s when I started bleeding. The pain was a 6 out of 10. It lasted until 1 pm. I laid back down and went to work at 10 pm the same night. Ladies, you got this. You will get through this. After that, I said never again and got scheduled an appointment to get my tubes tied next month! OUR BODIES, OUR CHOICE!! Be safe, ladies, you got this."

7 / 10
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  • SJ6...
  • Taken for less than 1 month
  • November 16, 2022

For Cervical Ripening "Just prior to having my hysterectomy, resection of endometrial polyp (Myosure) and Mirena insertion under general anesthetic, my surgeon came back into the room and gave me 2 tablets to insert into my vagina, saying they would help open my cervix. After approximately 30 minutes, I started having strong cramps similar to very bad period pain. This was shortly followed by diarrhea and sickness. Thank God the hand basin was next to the toilet so I could rest my head against it during the spontaneous diarrhea and sickness. The cramping pain continued, and I broke out in a cold sweat. After my 4th or 5th journey to the toilet, I asked the nurse for some painkillers. I told her what was happening, and she told me that this was not unusual after being given misoprostol suppositories. The surgeon had not mentioned any possible side effects to me. I ended up throwing up the paracetamol. Shortly after, I was taken down for surgery. I woke up in the same pain, and my blood pressure was through the roof."

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  • Jan...
  • November 28, 2019

For Abortion "Took the second pill 34 hours later (I was 6 weeks). Took it by myself and asked a friend to come stay over. It took an hour to feel proper cramping after swallowing the pills. Make sure you take the pain meds 1 hour before, as that helped me. The second hour, I started bleeding like a slightly heavy period. In hour 3/4, that’s when I felt 8/10 pain. I vomited and was dripping in sweat from the cramps, got into the shower and put on warm water and sat on the floor for 15 minutes, which helped. This pain lasted 30 minutes. My friend helped towel me down, and I had a heat pack on my stomach and fell asleep for an hour. It’s now the next morning, and I feel back to normal, just feels like I did ab exercises last night. I just have light to normal bleeding. But if I can do it (my pain threshold is just below average), then you can too. I just would have preferred a quick thing instead of it dragging. But so happy to wake up normal-ish that it’s almost worth it."

7 / 10
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  • Cou...
  • October 23, 2019

For Abortion "This was the most painful experience of my life. I was told it would cause mild cramping. It is hard to describe the pain I felt 2.5 hours after having this inserted. The cramping started and was so aggressive it made me decide to never have natural birth. I was groaning so loudly in the prep room they had to expedite my DNC process. I could not breathe properly because of the pain, I was sweating through my clothes so much so that they had to give me fluids through IV. I pleaded with my nurses and doctor to give me more pain relief and begged God to make the pain go away. I prepped with 1000 mg ibuprofen, and this did nothing. I lost all feeling in my arms, hands, and fingers and went into a trance-like state. I honestly wish I had passed out because the pain was so intense. To anyone who deals with regular period cramps, just prepare for this to be the most agonizing pain you’ll ever experience. I felt like I was literally dying from childbirth."

7 / 10
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  • Cca...
  • Taken for less than 1 month
  • December 15, 2020

For Abortion "I was 7 weeks and 1 day. First, I took the mifepristone in the office and got a little nauseated, but that’s all. The doctor then told me to insert 8 misoprostol vaginally by the time I went to bed that evening. I ate, and I took Tylenol with codeine 30 minutes before I inserted them. An hour went by, and I was in pain, but definitely tolerable, but it intensified along with shivering really bad, so I got in the bath. I then threw up all the food I ate, but felt tons better, but was still shivering and started to bleed. I finally went to lay down, and my boyfriend got me a heating pad and helped me a lot. I fell asleep due to medication, then woke up an hour later with pretty bad cramping. Passed some clots and tissue and felt much better. It’ll be okay, ladies, promise."

10 / 10
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  • Tin...
  • Taken for less than 1 month
  • June 7, 2024

For Abortion "24 hours later at 3 pm the next day, I put the 4 pills in my cheeks. I took anti-nausea medicine 30 minutes before and diclofenac 100mg. I also had my hot water bottle with me. I was ready, bracing myself for the worst while hoping for the best. 30 minutes later, I chugged down what was left of the medication in my mouth with water. I had already started cramping at this point. 5 minutes later, it started getting worse. 10 minutes later, it was really painful. I was rolling around in bed. Another 10 minutes later, I was kind of screaming and also on the toilet. After 5 minutes of sitting there, I was throwing up and having diarrhea simultaneously. I was shaking and sweating because of the pain. Everything was unbelievably painful. 1 hour later, I was still not bleeding. That was worrisome to me because I was already exhausted. I eventually bled a lot, with lots of blood clots and spent lots of time sitting on the toilet. I threw up twice. Pain level: 100."

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  • Tfd...
  • Taken for 1 to 6 months
  • December 18, 2024

For Abortion "I was five weeks and going when I found out. Purchased the drugs on Friday, got it by Monday. Was literally in the review page for days because I was so scared of side effects or if something could go wrong. Took the first pill, Mifepristone, by 9 in the morning the next day. Just felt a slight pinch in my stomach here and there, nothing serious at all. Twenty-four hours came by and I took the last pills, misoprostol, let it dissolve under my tongue for 30 minutes, and then took water to wash the remaining down. Others said it took a couple of hours, but mine took up to ten minutes. I began to feel cramps and was in pain. It was like that for 30 minutes, I began to bleed, and then while at it, I passed out a clot. The pain was much because I didn’t have ibuprofen. I started bleeding heavily and it was like that for about five days. In total, I bled for 8 days. I had headaches, diarrhea, cold, a bit of back pain, and running temperature while in the process. Good luck to you ladies."

8 / 10
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  • Can...
  • January 21, 2021

For Abortion "I’m posting this to try and help/reassure anyone who was in my position. I was 6.5 weeks along, took the first medication in the doctor's office at 1 pm on Friday. Took the 2 misoprostol tablets by dissolving in mouth at 5 pm the day after at home. I was so terrified, but honestly, it was an easier process than I expected. Just keep on top of your pain medication! The doctor had given me 600 mg ibuprofen and codeine tablets, which I took an hour beforehand (4 pm) and again 4-5 hours later. Bleeding started around 6:30/7 pm and continued quite heavily for about 3-4 hours. The pain was intense (stronger than period cramps), but a hot water bottle and walking around slowly helped a lot. The pain was gone completely about 6-7 hours after taking the second medication. The bleeding continued for about 2 weeks afterward, with cramping for a few days, but got lighter as the days went on. I’d advise anyone doing this to take 1-2 days after to rest at home and recover. You can do this! x"

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  • Ano...
  • Taken for less than 1 month
  • October 16, 2021

For Cervical Ripening "I inserted two 200 mg tablets vaginally 8 hrs before surgical hysteroscopy for an endometrial polyp. This turned into one of the most traumatic experiences of my life. Pain started abruptly within 45 minutes, and it was agony. I tried taking pain meds but vomited them up almost immediately and then vomited continuously for 4 hours (mostly dry heaving as I was empty). Badly dehydrated. Severe shivering/chills. When I arrived at the surgical center, I collapsed on the floor of the lobby. It took a LOT of preoperative medication to get my pain/symptoms under control enough to do the surgery, and they had to switch from sedation to general anesthesia. When I woke up, the same terrible pain was still there, and I was maxed on narcotics before I was stable enough for discharge. Now, 12 hours later, the pain is manageable but not gone, and I’m incapacitated by pain, meds, exhaustion. The good news is the surgery was a success (a previous attempt w/out failed and created a false passage)."

3 / 10
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  • Dsi...
  • November 9, 2021

For Cervical Ripening "Horrible. Pain started within minutes of taking it. Took at 10 pm and was unable to sleep. Spent the night feeling sick, tossing and turning. Upon arriving at my appointment after 2 attempts to do the procedure, the doctor was unable to continue. My cervix was still tight despite the pain. Now I have been scheduled for the procedure at a hospital. This was on Thursday night to Friday morning. It is now Monday, and my body just feels off. My body aches, breasts hurt, and I have a horrible migraine. I just feel weird, as if my body has gone through something. Not the best experience."

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  • Emi...
  • October 16, 2019

For Abortion "I am a college student, and when I found out I was pregnant, I instantly knew I wasn’t ready for that, so the decision was pretty clear for me. I went to the doctor and was told I was 6 weeks 3 days. I was given the first pill by the doctor and took it there, and then went home and took one nausea pill and one Tylenol with codeine. 30 minutes later, I inserted the 4 misoprostol pills into my vagina and waited. About two hours later, cramping started but I hadn’t started bleeding yet. An hour or so after that, the pain became unbearable (and I have a very high pain tolerance), so I sat on the toilet while clots came out and then took a steaming hot bath. I was rocking back and forth, taking deep breaths. I took another Tylenol and then went to sleep. I woke up this morning and had bled through my maxi pad, but no cramps anymore, and pregnancy symptoms have started to go away! Worked well, but for me, the pain was definitely 10 times worse than “bad period cramps.”"

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