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Mirtazapine for Depression User Reviews (Page 4)

Brand names: Remeron, Remeron SolTab

Reviews for Mirtazapine

Commonly mentioned side effects
  • hel...
  • Taken for 1 to 2 years
  • May 13, 2021

"This medication has helped me tremendously. Though I had to find out the hard way from the previous medication, which I tried for at least 4+ weeks to give it a chance, but got extremely worse quite quickly. Very bad thoughts that I wasn't experiencing before made everything I was trying to fix worse and more. I know people on the other med that swear by it, so it just proves how hard it is to find the right one for each individual. This is definitely the right one for me and also helps with sleep."

10 / 10
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  • mqu...
  • Taken for 2 to 5 years
  • December 19, 2012

Mirtazapine "Mirtazapine has helped me on more than one occasion. I've cycled through the gamut of antidepressants including but not limited to Prozac, Zoloft, Paxil, etc., but nothing really worked until Remeron. Thought I was okay to stop all medicines a year ago and did fine for a while but now feeling awful again; depressed and underweight. Renewed my script today and taking my first dose of Remeron tonight. Bring on the munchies! I just love a donut."

9 / 10
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  • Mal...
  • Taken for 5 to 10 years
  • August 31, 2015

"After years of chronic depression and a significant suicide attempt, I was institutionalized. During this time, the supervising psychiatrist prescribed mirtazapine. This drug saved my life. I am on a high dose, 60 mg before bed, but I have noticed no side effects other than a more restful night's sleep (I was an insomniac). My mood is entirely stable now, with any depressive episode being minor and totally manageable. There has been no noticeable stupefying effect, and I am not in any way sedated. In fact, my career has taken off since I commenced taking this drug. I understand that it is not for everyone, but I am one of its success stories."

10 / 10
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Frequently asked questions

  • Anonymous
  • Taken for 1 to 6 months
  • May 30, 2023

"I was prescribed 15 mg/day for depression with insomnia. While my sleep improved, I became very irritable and quick to anger. I had no patience. In addition, in only 4 weeks on this drug at what I was told was a low dose, I gained 10 pounds. I had terrible cravings, particularly for sweet foods, which is not typical for me. Even with regular exercise, I could not avoid the extra pounds. I am coming off the mirtazapine."

1 / 10
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  • HER...
  • Taken for 1 to 6 months
  • October 7, 2020

Mirtazapine "REMERON/MIRTAZAPINE was wonderful the first two weeks, particularly because I felt dismal for 50 years, then mirtazapine came about. But after two weeks of a new life of positivity, things changed to a life of pain, nausea, apathy, crying, worrying, close to zero motivation, even to use the restroom. I can go on and on, basically now I wonder why people live for 100% negativity, literally even when you list all things. I wish I never experienced the good from this drug because now mental torture and horrible chronic pains would best describe my life!!!"

1 / 10
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  • Ann...
  • Taken for 1 to 6 months
  • October 16, 2013

Mirtazapine "No effect on mood or anxiety, did help with sleep though. Gained 22 lbs over 3 or 4 months, which really made me depressed! Slowly tapered off on my own, am now losing the weight and just started Celexa. Can already feel a difference in anxiety level, am amazed."

7 / 10
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  • Anonymous
  • August 2, 2012

Mirtazapine "Great, SSRIs do next to nothing for me but this has helped a TON. I tried Zoloft, Paxil, Prozac, etc., and they did very little for me but the week I started on Remeron 30mg, I felt so much better, almost like myself again."

10 / 10
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  • bum...
  • June 16, 2016

Mirtazapine "At first, I took Remeron and I was knocked out for a full day. I was underweight and had panic anxiety. This really helped me. After the first day, my body seemed to adjust to Remeron and by the 3rd day, I didn't have any tired feeling at all. It definitely helped me with sleep. I am now on 30 x 2 tabs a day and have been on this for years. I am actually afraid to get off of it. It has helped me through very difficult times."

7 / 10
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  • Dal...
  • September 22, 2009

Mirtazapine "I have been on Remeron (now Mirtazapine generic) for about 9 years now. It works great and I have NO sexual side effects, in that I can easily have an orgasm, which other SSRIs that I tried would not allow."

10 / 10
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  • Mir...
  • January 27, 2013

"So far I haven't seen anyone on here that's been on Remeron/Mirtazapine 45mg at night for more than 6 years. I've been on it for 11 years. I was put on this medicine in 2002 after my daughter was born. To save all the details my physical and mental health went out to rest somewhere leaving me in a body and mind that didn't belong to me. They tried me on every medicine available and nothing worked. The negative long term of this has been: weight gain, dizzy sometimes, dehydration and laziness. The positive is it gave me my life back. I, like others here, have found it's notorious for appetite. I could eat sugar right out of the bowl. I have had to make myself be more disciplined in my eating and exercise. I combat dehydration by keeping a cup of water with ice in it filled and drink on it all during the day. I am also moving into menopause so have to be very careful. I've heard some talk about the nightmares. Yep, have them too but only if I eat sugar before bed. Lay off the food 4 hours before you go to bed and it will get rid of those monsters under your bed. I have post-traumatic stress disorder and that causes most of my nightmares. Still, my sleep is awesome. I still have some anxiety from time to time but use Klonopin 0.5 to cut the edge off only when needed. I tried going off about 5 years ago and after about 3 days I couldn't sleep, think, or operate at any type of normalcy. I will have to add I also gained a concentration level I never had before. I went from a school drop-out that couldn't learn to a 3.9 GPA (40-year-old) who loves to read and learn! Compared to all the other stuff out there (and their side effects) I would have to say Remeron has proven to be the very best antidepressant I've ever taken."

9 / 10
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  • kml...
  • Taken for 6 months to 1 year
  • February 1, 2014

Mirtazapine "I have been on Remeron since last April. Wonderful!! Nothing else worked...tried everything in the past 4 years. Gained 20 pounds but was so happy to feel better until my blood work showed a high increase in my cholesterol which is stated in info so check yours out. I am now trying Paxil but if does not work will have to go back on Remeron and a Cholesterol pill which I am not happy about but the good outweighs the bad. Anyone else have this problem..."

9 / 10
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  • edd...
  • Taken for 2 to 5 years
  • August 29, 2013

Mirtazapine "They gave me Remeron in the hospital. I took it for two and a half years. It worked wonders for me. I have had no luck at all with SSRIs. My doctor told me that usually people who have no luck with SSRIs usually have good luck with tetracyclic antidepressants. The only drawback is I gained 85 lbs, which, needless to say, did not help my self-image. I'm considering Ludiomil (maprotiline)."

9 / 10
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  • pet...
  • Taken for 1 to 6 months
  • September 27, 2024

"Hands down the best and most effective antidepressant I’ve tried. I’m on 45 mg, and it has been a lifesaver, no exaggeration. I sleep through the night (with help from 300 mg of quetiapine), I wake up feeling rested, ready, and motivated to start a new day. This AD is one that doesn’t make me sweat, most of them caused hyperhidrosis for me. I have no side effects, no weight gain, no appetite changes, which surprised me. I finally have the energy to keep my day going. I can finally say that my depression and anxiety are in remission."

10 / 10
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  • Spe...
  • Taken for less than 1 month
  • July 14, 2019

Mirtazapine "After taking this one week, I have to say I am totally sedated. If we had an earthquake (CA), I wouldn’t be able to get off the bed. I am quitting now. I am a fall risk, new widow, and anxious. I feel like this drug is changing my heart rate and I have a horrible headache. Almost ER time. Please tell me someone, how long is this in my system? I am worried I’ll be in bed all day. Literally can’t stand up, and this is after 12 hours of sleep."

1 / 10
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  • nia...
  • Taken for 1 to 6 months
  • October 2, 2020

"I’m on mirtazapine 15 mg. It works for me, but I’m asking my doctor to up the dosage soon, as I’m still not 100%. I experienced severe side effects on SSRIs (Prozac), so this is a good alternative (as it’s a NASSA). The side effects I experienced were quite bad lethargy and tiredness for the first 5 days or so, but after more than 2 months on it now, it doesn’t make me tired at all. I’ve also experienced weight gain, but that outweighs the benefits of this drug, so I’m happy to stay on mirtazapine despite that. Overall, I would definitely recommend this drug, especially to those who can’t be on SSRIs or SNRIs. (Also, I’m in the UK, so the insurance questions don’t really apply to me, but I pay the standard £9.50 or so for my prescription.)"

9 / 10
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  • Anonymous
  • Taken for 10 years or more
  • April 18, 2024

"I’ve had a tough life from birth on. At 17, I finally found out what had been holding me back. Diagnosed with Klinefelter's Syndrome. Was suicidal from the age of 8 on. It got much worse after the diagnosis. Life just sucked! Depressed, high anxiety, social phobia, severe insomnia, and had a death wish until my shrink prescribed Mirtazapine. I’ve been taking it for 25 plus years with no major side effects. I sleep soundly for 8 hours, zero anxiety, and life is worth living. It saved me from suicide. Now I only use it for sleep. It is difficult to wean off of, but if you are like me, there isn’t a need to wean down. If it works, let it work. I take 45mg at night. It does have a more sedating effect on lower doses, but my happy place is at the max dose of 45mg. Most drugs stop working after a period of time. Mirtazapine never fails at what it was made to do!"

10 / 10
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  • Anonymous
  • April 15, 2012

Mirtazapine "I've been on Remeron for nearly two weeks now, and I can feel my mood elevating and depression decreasing already. Also, I'm now getting full nights of sleep, which is also an amazing feeling. The only downsides I've seen so far are some grogginess in the morning (though that has been less and less noticeable) and ravenous hunger (this has not gotten less). Luckily, because now I'm starting to actually want to leave the house and do stuff, I've been able to work out pretty consistently this past week, and hopefully that will counteract the effects of me eating the weight of a horse every day. I've tried more antidepressants than I can count on one hand, and this is the first time in a long time I've started to feel better."

9 / 10
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  • Ayd...
  • February 25, 2016

"This medication worked within 2 or 3 days and now I am back to my normal, happy self. My depression journey: Depression started to show itself during year 9 of high school, and continued to get worse until I finally reached 20 years old and decided it was time to get help. I started seeing a doctor who prescribed SSRI sertraline, then went on to see a psychologist, and finally a psychiatrist. During this time, I went through ZOLOFT 200mg, Celexa, Cymbalta, and while Zoloft 'helped' a little, it wasn't until I tried Mirtazapine (Avanza, Remeron) 15mg that I finally had a restful sleep, my appetite came back, and my smile returned, my self-esteem improved, and I suddenly realized I was back to normal. And my libido returned! Keep going, never give up!"

10 / 10
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  • Ash...
  • Taken for 1 to 6 months
  • February 14, 2020

"This drug really worked for my depression and insomnia. It really helped me, but... I just could not control my appetite. As soon as I woke up, my first thought was eating, and after eating, I was thinking what to have next. My hunger was so out of control that I would eat until I was sick. I ended up gaining 25 lbs in 2 months. I had munchies from dawn to dusk. It was horrible. I don’t know if anyone else had this happen, but I had to get off of them, and since have lost 20 lbs of the 25 I gained. I would recommend if you can control your hunger, because I sure couldn’t."

8 / 10
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  • itg...
  • Taken for 1 to 6 months
  • July 27, 2017

"I suffered from insomnia, anxiety, and depression. Over the course of 2 years, I have tried citalopram and sertraline. None of these have been as effective as mirtazapine, to the point where friends, family, and colleagues noticed huge positive changes in my personality. I started on 15 mg, which instantly cured my insomnia (WOW!) and a lift in mood (after a week). After 2 weeks, I requested my GP to put me on a standard dosage of 30 mg. I have been on this for 2 months (best effects after week 4) and I FEEL GREAT! I am happy, outgoing, eating and sleeping properly again, and finally feel the old fun, strong me is coming back. There are odd bad days, but now it is easier to SNAP OUT OF IT and get back on track. THANK YOU, MIRTAZAPINE, FOR GIVING ME BACK MY JOIE DE VIVRE!"

10 / 10
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  • Yip...
  • September 12, 2017

Mirtazapine "I take Remeron SolTab (Mirtazapine) half an hour before bed for insomnia and depression, and it has completely removed all my symptoms. Highly recommend for anyone with insomnia, depression, or anxiety. It is also superbly effective for allergies and takes care of my runny and stuffed nose. It may be the strongest yet safest antihistamine for rhinitis. Sleep is good and refreshing. Not taking anything else, not needing anything else. Took me out of a really dangerous time in my life."

10 / 10
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  • jme...
  • Taken for 1 to 6 months
  • March 23, 2021

"I envy so much all you people who have had benefit from this medication. The only thing it helped me with was pretty much instantly I was sleeping again (6-8) hrs per night compared to the 3 hours leading up to taking this medication. Despite constant exercise, within 2 weeks, I'd put on 6 kgs around my midsection. I was told it can take up to a month to work properly. It's now been just over a month that I've been on 30 mg, and I can completely understand why people commit suicide. Constant despair and crying over things that aren't relevant. Zero motivation or energy to do anything. I see nothing but despair and pain in my future. I will take my chances with no medication at all."

1 / 10
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  • ED...
  • Taken for less than 1 month
  • April 2, 2013

"In reading through these reviews, I really was very skeptical. But... After close to 1 month, I actually have the feeling as described 'the veil has lifted'. I really feel better! The increased hunger has subsided. I coped with that by eating lots of oranges and apples (very filling)! I sleep well and wake up feeling rested. So, please do not give up. It does work. Concentrate on the good, not the side effects."

9 / 10
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90 Report
  • mfs...
  • Taken for 6 months to 1 year
  • December 30, 2014

"This has seriously been my miracle. After trying 5 different SSRIs with horrible side effects, Remeron literally saved my life. I was given it during a hospital stay (I was suicidal). The only side effects I've experienced were sleepiness (in the first few weeks) and increased appetite (ongoing). Personally, my depression caused me to have no appetite at all, so the increased appetite was a welcome effect, although it may not be for others. I can sleep, I can eat, and - most importantly - I can live. I can get out of bed in the morning and live my life. I am on 45 mg once a day (at night). With this medication, in combination with CBT and mindfulness meditation, my depression is almost completely gone."

10 / 10
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  • FLG...
  • Taken for 1 to 6 months
  • March 24, 2017

Mirtazapine "This medication was the magic bullet for me, anxiety-wise and depression-wise. I slept extremely well, and my anxiety plummeted. I would have definitely stayed on it if it weren't for the atrocious weight gain! I am normally 110 lbs or so, and within 1.5 months, I was up to 130 lbs! During this time, I wasn't eating much more than normal, and I was skateboarding, canoeing, and running, yet still putting on weight. I was the happiest, yet the fattest I had EVER been on this drug, so it was a love/hate relationship. I decided to go off of it because I couldn't tolerate the weight. It was a shame since it was extremely effective for me otherwise. Oh well."

9 / 10
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71 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.