Mirtazapine User Reviews & Ratings (Page 5)
Brand names: Remeron, Remeron SolTab
Mirtazapine has an average rating of 6.8 out of 10 from a total of 2,085 reviews on Drugs.com. 56% of reviewers reported a positive experience, while 21% reported a negative experience.
Reviews for Mirtazapine
- Mir...
- Taken for 2 to 5 years
- November 21, 2013
For Insomnia "This pill gives me an appetite, helps my depression, helps my anxiety, and helps me sleep. I love it. I don't know what I would do without it, to be honest, and if I need to be on one medication for the rest of my life, this would be it. I have been on many pills, and I'm normally really picky about side effects, but this one is just great for me."
- she...
- Taken for less than 1 month
- July 13, 2023
For Anxiety "I wasn't sure whether to take this. Fluoxetine and propranolol put me in the hospital, but I decided to give it a try. The first week was amazing, I felt so much better. I'm currently in menopause and experiencing menopause anxiety, which I've never had before. I'm now on week 3 and have had a few bad days, but I understand it can take up to 6 weeks to work. All I can say is that if you've tried everything else and it hasn't worked, this antidepressant does. As for the weight gain and hunger, it only lasted the first week and I don't feel like that anymore. Compared to how I felt weeks ago, when I didn't want to be here, this medication has saved my life. I highly recommend it and don't plan on stopping it anytime soon."
Frequently asked questions
- Nev...
- May 14, 2020
Mirtazapine for Depression "I literally split a 15mg down to into 8ths because my body is so sensitive. Wow... I have been out of it for DAYS. I cannot stop sleeping. Put me in a horrible weird state like I don't know what's going on or like I'm truly awake. Just feel 'out of it'... Off of a sliver! I have read contradictory things about dosing. I would indeed say and agree with that the lower doses are VERY sedating. Very weirdly vivid (not nightmarish) dreams... I had a gene test done and this medication was on my 'lower doses maybe be required'. I can't even imagine what a high dose would do! This is completely staying on my 'NO!' list! Be careful of this medication because it is POWERFUL. I feel like I've just been high for days. Like I've just been smoking the most dank weed and I've just been stuck in this high. When I wake up, I feel like I'm manic, like I just have a huge rush of anxiety. I wanted to try this because I am experiencing 'heartburn' like chest pain that isn't acid-related at all."
- lor...
- Taken for 10 years or more
- October 22, 2023
For Insomnia "I have always had a problem with sleeping, even as a 7-year-old. When I turned 40, the problem got so much worse, and the anxiety from not sleeping caused me not to sleep for months. My doctor prescribed mirtazapine, and I agree with a lot of comments on here that say it saved my life. I was ready to end it all... I take 15 mg per day at night and sleep like a baby. I am now 74, so I have taken this for 34 years. Every once in a while, I tell my husband that I don't need it anymore, and maybe I should quit taking it. He says let me know when you stop so I have a chance to move out!!! This is a wonder drug. My new doctor decided that I should go off this medication for whatever the reason. I was a total basket case after 3 weeks... I don't know what I'd do if they ever took this drug off the market!!"
Are you taking this medicine?
Your review helps others make informed decisions.- Hap...
- August 2, 2015
For Insomnia "Have suffered insomnia and anxiety for 15 years. Slept 6 to 12 hours per week. SSRIs ineffective. Would visit Dr. every 2 to 3 months and beg for 4 sleeping tablets (I'm a Brit) because I was dizzy and almost crying with exhaustion. A new GP prescribed Mirtazapine, and I have slept a minimum of 6 hours each night from the start. Feel fantastic. Colleagues notice a difference, house is clean, bags of energy. P.S. no more horrible dreams either."
- sat...
- July 10, 2008
Mirtazapine for Anxiety "I had been taking Remeron for about 4 years for severe anxiety and insomnia. It works great and gets you back on a normal sleep pattern right away. Yes, the side effects do get less and less after a few weeks. I have stopped using it now."
- Joh...
- Taken for 1 to 6 months
- January 4, 2014
For Anxiety "I started taking 15 mg at night about 6 weeks ago for anxiety/insomnia and mood problems. I started to feel some relief after just a few weeks and have begun to feel a lot better as time goes on. My doctor advised me to increase my dosage to 30 mg (1 pill) after 2 weeks, but I found it was too much for me and I got quite overwhelmed by the way I felt while at work one day, which was not a pleasant experience! However, since going back down to half a tablet each night, things have really leveled out for me. My anxiety is much lower and I don't feel depressed at all. At present, the best part for me is being able to sleep well most nights, as lack of sleep was becoming a real problem. I do have to watch my food and alcohol intake, but that's a good thing!"
- Anx...
- Taken for 1 to 6 months
- February 27, 2025
For Anxiety "I had anxiety and panic attacks for about 20 years before seeking help. I started therapy and was prescribed an SSRI. It made me sick every time I ate. I kept losing weight. After several attempts at different SSRI medications, I was prescribed 15 mg of Mirtazapine. When I started Mirtazapine, I had lost 12 pounds in about one month from the previous SSRI. Day one of Mirtazapine, I had an appetite. I slept calmly the entire night. Within a week, I was able to try new things out in public, like going to restaurants by myself and signing up with a volunteer organization in which I did not know anyone. I felt like myself for the first time in 20+ years. However, within two weeks, my weight gain was more than what I had lost originally, so I was prescribed a 7.5 mg. Even with the lowest dosage, I gained 40 pounds in one month. I was told to stop taking it. I haven't had a medication that's helped since I stopped taking this in 2023. It was an amazing medication for me except for the weight gain."
- ste...
- Taken for 2 to 5 years
- July 20, 2014
Mirtazapine for Major Depressive Disorder "I was on Remeron for about 2 years before. Helped very much with my depression. But although I often felt very sleepy near the beginning of the treatment, the massive fatigue eventually subsided to an acceptable level. 20 mins after taking it, I'm ready for bed. I can't keep my eyes open no matter what. I just restarted Remeron two days ago after more than a year being on it. As I type this, I feel fogged over, sort of sleepy, and immensely 'munchie'. As before when I took it, I'd find myself waking up several times a night going to raid the fridge and cabinets for munchie or sweet foods (and meats! definitely craved meat all the time). So again, on Remeron: eating again, sleeping some, more relaxed, less sad."
- vic...
- Taken for 1 to 6 months
- July 3, 2024
For Insomnia "I started taking mirtazapine 4 months after having a baby as my anxiety was so bad. I was literally only getting 0-2 hours of sleep a night. I broke down due to having no energy from lack of sleep, so I went on mirtazipine as a last resort. The first 2 weeks were tough. I experienced blurred vision and felt drunk most of the time, but since then the side effects have worn off and I'm sleeping 6-7 hours a night now and feel much calmer. Please give these a go if you are struggling with insomnia. They honestly saved my life."
- TRE...
- July 14, 2019
For Insomnia "I have suffered from insomnia for decades to the point of job loss, self-medicating with alcohol, and then sleeping days at a time once I reached the point of exhaustion. On just 7.5mg of mirtazapine, I am a new human! I truly believe a very low dose is the way to go for insomnia. I suffer from depression, and I suspect PTSD. Melatonin, Nyquil, codeine, nytol, prescription sleep aids, even pain medications like Tramacet had zero effect on my sleep. I could be so exhausted I was impaired and still not sleep. It has only been 7 days, but on 7.5mg, I have NEVER slept like this in my life. I fall asleep in minutes, I only wake a couple of times a night, and my energy level is at a place it has not been for 20 years. I am a new human. And oddly, I have adversely experienced a decrease in my appetite. I was a major stress overeater and this has completely balanced me."
- Luc...
- Taken for 1 to 6 months
- June 16, 2014
For Anxiety "I have been on many medications, and this seems to be working the best. So far, so good and only getting better. I have never really been depressed, but I did feel weird and used to worry all the time and couldn't work out why (ANXIETY). I have been misdiagnosed with ADHD and Bipolar. All those medications made me worse (Zyprexa, Lovan, Lithium, Carbamazapine, Effexor). I now take 15mg of mirtazapine before bed and have accomplished more in 6 weeks than I have in years because I don't have that weird feeling hovering around me anymore. I think it would be wise for parents with 'ADHD' kids to get another opinion because it could just be anxiety causing concentration problems."
- Mlr...
- Taken for less than 1 month
- June 18, 2025
For Anxiety "I started taking mirtazapine 7.5 mg a few weeks ago to help with persistent anxiety around sleep. I’d developed a pattern of worrying about whether I’d sleep, which only made things worse. From the very first night, mirtazapine helped me fall asleep faster and stay asleep longer, something I hadn’t experienced in months. The sedation is noticeable (in a good way) at this low dose, and it feels natural — not like being knocked out, but more like your body finally gets permission to rest. Best of all, it significantly reduced the anticipatory anxiety I used to feel every evening. Knowing I’ll get sleep has helped reset my entire mindset around bedtime. I do wake up a bit groggy sometimes, especially on day 1, but that fades quickly and is a small trade-off for how much better I feel. I feel super relaxed now as if I can fall asleep anytime. Overall, 7.5 mg has been a game-changer for both my sleep and mental health. I’m incredibly grateful I gave this medication a try."
- Pre...
- Taken for 5 to 10 years
- March 24, 2023
Mirtazapine for Major Depressive Disorder "I read about Remeron somewhere online and asked my doctor for it. I take 30 mg daily. It helps with depression and helps me sleep. Take it right before you go to sleep. If you take it earlier, you might get hungry. Because this medicine makes food indescribably delicious. Get this drug. It will help you immensely. Good luck!"
- Cat...
- Taken for 6 months to 1 year
- February 10, 2015
For Insomnia "It used to take me a good 3-4 hours to fall asleep at night, now it takes me around 20-30 minutes. I feel much more energized during the day and actually enjoy sleeping again. It has also helped decrease the amount of nightmares I used to have."
- JCN...
- August 12, 2021
For Insomnia "It's irresponsible for people to scream in all caps, 'DON'T TAKE THIS DRUG!!!' especially after one night. ALL research supports low-dose (7.5mg) for insomnia. Anything higher is activating (there are always exceptions) on norepinephrine. Not everyone gains weight. Diet and exercise will keep the weight off if you do gain weight, just as it will without taking it. And this discussion board is for insomnia, not anxiety or depression. Low-dose for insomnia/per peer-reviewed science!"
- Atr...
- June 27, 2023
For Insomnia "I am a senior and expected to be calmed by this drug. It did the opposite. The 7.5mg dose made me more alert, gave me severe dry mouth, made it harder to urinate, and never gave me a really relaxing and calm moment. Even after 12 after taking the drug, I was unsteady on my feet. The problem with these sleeping medications is that they have such varied effects on people. The doctors have no idea if these medications are going to help or going to hurt the patient. Too often it is trial and error. It's like going to a witch doctor. Maybe the sleep medicine will work or maybe not. Of course, the doctors want to help, but the reality is that they actually don't any more than the collective intelligence of the posters on this thread."
- Dop...
- Taken for 1 to 6 months
- January 4, 2016
For Insomnia "I have experienced sleep problems for 10 years, lost both parents, have a very busy life, house to run, full-time physical job. I was a complete wreck, worn out physically, to the point I couldn't function or speak even to people. I dreaded going to bed and sat up all night trying everything to get to sleep. I had to be up for work at 5.30, driving on motorways felt like a zombie. These tablets are my lifesaver. I've got my spark back, no side effects, only aches in my joints, but that's nothing to me. I feel human again, no weight gain which is fantastic. I was scared of the weight gain, but I have been fine. Don't be scared of trying them, they're a savior."
- Anonymous
- Taken for 2 to 5 years
- June 1, 2019
Mirtazapine for Depression "I've been on Remeron for several years now. Primarily for insomnia but also for anxiety and depression. This medication helps me tremendously like no others I've tried. No side effects besides hunger and weight gain. Highly recommend"
- han...
- Taken for 1 to 2 years
- April 19, 2023
For Obsessive Compulsive Disorder "I was prescribed mirtazapine when I was in a severe anxiety episode. I felt extremely anxious all the time for several weeks and could hardly function, eat, or sleep. I also have been diagnosed with OCD. It's been a miracle drug for me! I started on 7.5 mg, and literally the first night after taking it, I was able to sleep, after not having been able to sleep without Ambien for weeks, and I woke up with an appetite, which I hadn't had in weeks. Its effectiveness increased for the next week until my anxiety was only about a quarter of what it had been before. I ended up increasing it to 22.5 mg daily, and I've been on that dose for about 1.5 years now and will likely be on it for the rest of my life, or until it stops working for me. It's been a lifesaver for me! Everyone is different, but I just wanted to share my positive review as I know this kind of review can skew negative."
- Anonymous
- Taken for 1 to 6 months
- August 23, 2024
For Insomnia "Honestly, thank God for mirtazapine. I usually don't review drugs, but this one really, really helped me. I took the full dose, and it knocked me out. I also slept for 13 hours, but it made me a zombie for the first day and I had extreme difficulty staying awake. It also lasted about 3 days where I was pretty out of it. I cut the dose into fourths, and I still fell asleep within 15 minutes of taking it and slept through the night. I woke up, and I was still groggy, but the benefits far outweighed a little fogginess. It led to me getting 7-9 hours of consistent sleep, whereas it had been taking me between 3-5 hours in bed before I fell asleep. I had been waking up multiple times in the night, and I was only sleeping between 4-6 hours. I've been taking it for about a month since then, and some days are better than others, but it has been pretty consistent and helpful for me, in particular with the sleep onset time."
- BLE...
- Taken for 1 to 2 years
- March 12, 2024
For Insomnia "For me, very low doses of 1-2 mg work best. I cut up pills into very small particles for this purpose. I sleep well and do not have the morning drowsiness that I experienced with higher doses (3-4 mg)."
- Mar...
- Taken for 2 to 5 years
- August 4, 2024
For Insomnia "This medication was a godsend for me. Started on 7.5 mg for the first week, then went up to 15 mg for the next 3.5 years - have been sleeping 9.5 hrs a night. Just last month I started waking up early at around 5 am - not sure why. Only drawback is that it gives me the munchies. So I don’t know why I now wake up early. Maybe I didn’t thank Jesus enough? Maybe I should increase the dose by 7.5 mg? Will try."
- Ano...
- Taken for 1 to 6 months
- August 12, 2019
Mirtazapine for Depression "I was started on 7.5 mg of Remeron when I was having anxiety and panic attacks. Within a few days, I started feeling significantly better. A few months later, and I have had only a few minor episodes of panic. It has greatly improved my life with no major side effects."
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Mirtazapine for Major Depressive Disorder "I love Remeron! Even though it doesn't work sometimes, it definitely helps with mood, sleep, and your appetite when it does. I guess because I've taken it for so long, my body thinks it's a Skittle. But skipping a week or just taking it when needed has better results for me. Without it, I tend to lose weight every day from the effects of not eating when I'm busy. This helps me to keep my appetite and energy up until the next dosage. I hope this post and the medicine helps someone else as well. Just do not forget about the symptoms, be prepared for them, and enjoy your life on Remeron!"