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Metoprolol and Tiredness: What Users Say

Brand names: Metoprolol Succinate ER, Metoprolol Tartrate, Toprol-XL, Lopressor, Kapspargo Sprinkle

Tiredness: mentioned by 104 users (15.9%)

Based on user experiences from 653 Metoprolol reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

tiredness 15.9%
dizziness 11.8%
fatigue 9.3%
shortness of breath 8.9%
anxiety 8.7%
heart palpitations 7.5%
insomnia 7.4%
depression 6.4%
weight gain 6.1%
headaches 5.5%

Reviews for Metoprolol

Commonly mentioned side effects
  • Blu...
  • November 18, 2019

Metoprolol for High Blood Pressure "This is the worst blood pressure medicine I have ever taken. It caused me erectile dysfunction, memory loss, and tiredness. It also gives you blurry vision. Stay away from this bad medicine. When I stopped taking this Metoprolol Succinate, my erection got better, I felt much better and more energetic. This medicine will definitely harm your body."

1 / 10
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  • Lil...
  • Taken for 1 to 6 months
  • February 20, 2017

For High Blood Pressure "Stay away from this drug. Real bad side effects. Tired all day. Anxiety, panic attacks. Can't breathe. Short of breath. Feels like your organs are shutting down slowly. They should lock the doctors up for prescribing this poison medicine. Wow. I thought I was dying. And I think I came close. It messes with your eyesight and all. If you die and take this medicine, it's the reason. They will say you died from natural causes to stop a lawsuit. But this medicine is dangerous. I was only taking half of 25mg, dang near killed me."

1 / 10
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292 Report
  • Anonymous
  • Taken for 1 to 6 months
  • June 14, 2023

For High Blood Pressure "This drug has terrible side effects: 50 mg. I had bad chest pressure, shortness of breath, dizziness, swollen legs, ankles, and feet, depression, extreme tiredness, on and on. It did not lower my pressure, it actually increased my readings to over 200."

1 / 10
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Frequently asked questions

  • Anonymous
  • Taken for 6 months to 1 year
  • July 2, 2020

Metoprolol for High Blood Pressure "I’ve been on metoprolol for almost a year now. I am only 24 and high blood pressure runs in my family. My mother had a stroke from high blood pressure, and my grandfather passed from it. I had high blood pressure with my daughter, but it went away after I had her, and then I had my son and it never went away. I was on bystolic, and it worked great for me, but was too expensive. So, I was put on metoprolol 25 mg, and it didn’t really help my blood pressure. I was prescribed a higher dosage to 50 mg. I am constantly tired, I’ve gained weight, and I am having night sweats. If I don’t take it, my heart starts hurting, and I hate it. The only good thing about it for me is that it does help with my blood pressure and my chest pain."

4 / 10
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165 Report
  • Lyn...
  • Taken for 5 to 10 years
  • September 18, 2020

For High Blood Pressure "I had extreme high blood pressure and arrhythmia. My ears were ringing, and I had blackouts. I was told my insurance will only cover the metoprolol XL 200 mg. I only take a half every day, so 100 mg, and I'm always tired and have to drink Red Bull to drive, so it's defeating the purpose. I am a 30-year-old woman and have gained around 40 pounds on this medication. I was never told this would happen, and when I go to the doctor, they just say exercise, well, I do. It's the medicine, not me. I have swollen ankles and, worse, a giant water belly, it's high up and awkward and has ruined my life. It made me buy plus-size clothes and wrap it up like a wound. It's big and swollen. I'm quitting this rubbish today."

2 / 10
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  • Bsh...
  • Taken for 6 months to 1 year
  • August 16, 2021

Metoprolol for Supraventricular Tachycardia "I can't believe it took me this long to correlate my symptoms with this pill, and I'm a 25-year-old RN. Forty-six years old and have had SVT since my 20s. A couple of years ago, I had a 24-hour stay to evaluate HR of 165. All testing normal. No treatment. A year later, back in the ER with a pulse of 250. I was given Adenosine to convert me and then given Metoprolol Succinate 25mg daily. I've been on it for a year. I noticed some tiredness but nothing major. Over the next year, my tiredness became debilitating, and I suffered severe depression, insomnia, and panic attacks. I didn't make the connection and blamed it on the pandemic and all the isolation and restrictions everywhere. I thought I was just having a hard time. Then the drenching night and day sweats started. Still, I blamed it on perimenopause. But then came the heat and activity intolerance. Minimal activity caused me to become SOB, shake, and be drenched in sweat. Sleep was non-existent. I began having numbness in legs and feet."

1 / 10
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  • Mar...
  • Taken for 6 months to 1 year
  • June 13, 2022

Metoprolol for High Blood Pressure "Heart rate goes to the 30s. Gives me shortness of breath, feel sick. I have no energy. Taking 50 mg Metoprolol Tartrate three times a day per doctors' orders, but I feel like I'm overdosing. I believe this medication is poison. Slowly cutting back and getting off this medication. Have to go to doctors, and they just tell me to ignore side effects. I will not ignore them, and I'm getting to where I don’t trust doctors."

1 / 10
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More FAQ

  • Ebj...
  • October 12, 2019

For High Blood Pressure "I am 25 years old and my BP is normal all the time. My cardiologist, Dr. [corrected_text] told me I have a weak heartbeat, so he prescribed this pill, metoprolol succinate 25mg ER. In the first week of taking this pill, I felt nothing. By the second week of taking it, my skin felt itchy, and I felt like I've been bitten by an ant all over my body. I also felt severe tiredness when I took it in the morning. I can't fight it and end up falling asleep. I also feel pain when I press my head or put pressure on it. I also wake in the middle of the night with horrible dreams and feel like my heart beats faster. My cardiologist told me to take it at night, and so I did. It works okay, but I want to stop taking it before my body gets used to it. I am healthy, do not have any illnesses, do not drink or smoke, and I am active. Due to a diagnosis of a weak heartbeat after giving birth, I have this pill. I hope I can read a review from someone who has stopped taking it."

2 / 10
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130 Report
  • gre...
  • Taken for less than 1 month
  • October 18, 2022

For Atrial Fibrillation "About 2 months ago, I started having issues with my heart beating fast and many more symptoms. 2 weeks ago, my new heart doctor (never had to go to one before) put me on 100 mg metoprolol right off the bat. The first day I literally passed out. I called my doctor, and he bumped me down to 50 mg. I've only been taking 25 mg. Every day I take it around noon, and within 2 or 2 1/2 hours, I can feel when it kicks in fully. My side effects I've experienced so far are: extremely fatigued, heart feels like it's beating out of my chest, nightmares, intimacy issues, vertigo, constantly feeling sick like I'm going to pass out, weak, tired, feet are freezing, and I have trouble sleeping. I go to the doctor in 3 days, and I'm going to inform him (even more than I already have) that I want off this medicine. I'm hoping to figure out the cause of my original problem and how to fix it, since instead of one issue, I now have about 12 issues daily. I would never suggest this medicine to anyone, it is absolutely horrible."

1 / 10
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70 Report
  • Ter...
  • April 2, 2014

For High Blood Pressure "I have been on Metoprolol ER 25mg for 10 months. It has worked great for my blood pressure and I have had no migraines or headaches. I do get really tired in the afternoon, which I never used to. The worst part is I have gained 22 lbs. and nothing I do reduces the weight. I work out 4 times a week, really watch what I eat, and nothing helps."

7 / 10
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183 Report
  • Rob...
  • July 28, 2014

Metoprolol for Heart Attack "I'm a 52-year-old male in fairly good shape. I started taking Metoprolol, 50mg twice a day after suffering a cardiac arrest earlier this year, in April. It has been very effective in controlling my blood pressure and keeping my heart rate low. The side effects are becoming unbearable now, though. I'm tired and have a lot of trouble focusing on my work during the day. I have a lot of restless nights of tossing and turning, and have now developed a rash under my arms. I think it also contributes to erectile dysfunction. I spoke to my cardiologist about all this today, and he's cutting my dose in half. I'm hoping some of these side effects will diminish when I cut down to 25mg twice a day."

8 / 10
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159 Report
  • sca...
  • Taken for 1 to 6 months
  • March 6, 2013

For High Blood Pressure "After taking this medicine for a week or two, I experienced numbness (lack of blood flow) to my fingers, usually in one or two fingers. This also happens with my toes. I have really high blood pressure, and it does lower it, but the numbness, which usually lasts about 30 minutes but returns throughout the day, is scary. It also gives me terrible nightmares, very violent. I wake up wondering how I could even have such terrible dreams. It also makes me tired. I've stopped it several times, and each time the bad symptoms go away completely in about 2 days. I'm going to have to stop taking it for good, the nightmares are just too terrible."

1 / 10
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  • Koa...
  • Taken for 1 to 6 months
  • August 8, 2020

Metoprolol for Supraventricular Tachycardia "I was diagnosed with SVT's and put on metoprolol - which has helped a lot with my palpitations. Instead of multiple times per day I now only get palpitations a few times a week. I first started out on 25 mg. in the a.m., but that didn't do the trick. Then went to 25 mg. twice a day, however, that made me extremely tired. Now I take 12.5 mg. in the a.m., & 25 mg. in the p.m. and this works! My resting heart rate has decreased between 55 - 60 bpm. But... everyone metabolizes meds differently."

10 / 10
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  • Str...
  • Taken for less than 1 month
  • January 7, 2021

For Premature Ventricular Depolarizations "No prior history of cardiac issues or anxiety, 30-year-old female, been working through COVID as a nurse, unsure if I ever had COVID. Was recently diagnosed with “stress-induced” PVC/PACs, symptomatic and pretty frequent but not enough to require any immediate treatment when I went to the ER. Thought it was anxiety, then it persisted every couple of minutes, a swift kick to my chest, losing my breath, so I gave in after almost a day of relaxation techniques. The ER doctor started me on metoprolol. Awful. They helped the symptoms, but I felt like rubbish. Dizzy, tired, my vitals were fine, but just that 10-15 point drop in my blood pressure was giving me headaches and dizziness affecting me! My resting heart rate was in the 50s, which was concerning at first, but I was asymptomatic, so no issue, it gave me anxiety though and made me restless at night. I started on 50 mg, was only taking 25 mg by the end of it after 2 weeks and was switched to propranolol. Much better after a couple of days on that medication, way fewer symptoms."

4 / 10
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  • JJ ...
  • Taken for 5 to 10 years
  • July 24, 2013

Metoprolol for High Blood Pressure "I have been taking Toprol-XL for about 8 years now. I started at 10mg, then 50mg, and now at 100mg. It has brought my blood pressure under control - was 150/80, now at 130/70. Also brought down my heart rate, which was 88 resting to 60 resting. I am a light smoker who has asthma/mild COPD. Metoprolol has shown no effect on these conditions as my PF and FEV1 have not changed. PROS: Reduced blood pressure to normal, reduced anxiety levels. CONS: Tired (mild), weight gain (mild), erectile dysfunction (mild), heart skipping a beat (occasional only and mild)."

9 / 10
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  • gar...
  • Taken for 5 to 10 years
  • July 2, 2016

Metoprolol for High Blood Pressure "I can only take 1/4 of a 25 mg tablet a day, and I still get extremely tired. Any more and it makes my blood pressure go up. 1/4 tablet keeps my blood pressure pretty normal on systolic, but heart rate and diastolic are too low. I have trouble breathing."

4 / 10
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115 Report
  • Roc...
  • Taken for less than 1 month
  • September 28, 2017

Metoprolol for High Blood Pressure "Went to have foot injury x-rayed at urgent care and spiked a blood pressure of 195/110, maybe due to pain. Was given this by IV in the ER, then pills for 3-4 nights at home. It lowered my blood pressure by like 20 points per day, and I was fine for 2 days, but then had episodes of exhaustion to the point where I had to lie on the couch for hours to recover from simple housework like washing pots. Was also short of breath like I had run 5 miles. Swallowing felt weird. Got disoriented while driving. It's a 9 on effectiveness but can't tolerate the side effects. Am 63/F."

9 / 10
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93 Report
  • Anonymous
  • May 7, 2010

Metoprolol for Atrial Fibrillation "This medication has made me extremely tired. I also have forgotten to do simple daily routine tasks such as setting up the coffee pot at night. One short store trip, and I am exhausted! I will try something else."

5 / 10
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154 Report
  • Anonymous
  • May 7, 2010

Metoprolol for Atrial Fibrillation "This medication has made me extremely tired. I also have forgotten to do simple daily routine tasks such as setting up the coffee pot at night. One short store trip, and I am exhausted! I will try something else."

5 / 10
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  • Tre...
  • August 12, 2019

For Premature Ventricular Depolarizations "Was on metoprolol for 4 weeks. I had nausea, headache, no energy, stayed in bed for 3 days straight. It also dropped my blood pressure to 90/55 & stayed in that range. After that, Dr. took me off, no taper - just cold turkey. On day 3 of no metoprolol, I ended up in the ER with rebound PVC's. I was in a constant panic attack for the first 4 days of withdrawal. It is day 7 & the panic is gone, but still have anxiety, still have a bad headache & rebound PVC's. Dr. said it could take up to 3 weeks until normal. Never would have taken if I had known."

1 / 10
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  • Fre...
  • Taken for 1 to 6 months
  • July 8, 2018

Metoprolol for Supraventricular Tachycardia "I was diagnosed with moderate/severe obstructive sleep apnea and supraventricular 'events' 4 months ago. I was put on a ResMed PAP machine and Metoprolol Succinate ER 25 mg. I have gained 10 pounds. I feel: no energy, chest heavy, heart pumping weak, breathing decreased/light, affect flat, tired, constipated, I can't think. My events are rare now, but I don't know if my events were due to the sleep apnea and if the PAP helped decrease them because I started both med and PAP at the same time. I miss being extroverted, energetic, and outgoing. I don't know if there is any other treatment available. Ablation? I don't like this med."

5 / 10
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  • Con...
  • Taken for 6 months to 1 year
  • March 19, 2019

For High Blood Pressure "My husband has always been happy, driven, and energetic. He had bypass surgery and was prescribed metoprolol. He's recovered to a point but is depressed, lacks drive, and is tired all the time. He's also developed a cough that won't go away. After reading these comments, I'm going to get him off of this terrible medication."

1 / 10
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68 Report
  • ban...
  • Taken for 1 to 6 months
  • June 13, 2018

Metoprolol for High Blood Pressure "My experience with this drug was that I was always tired and had no energy. I was told that I had to take the drug once a day, and I took it when I got home after work. My blood pressure skyrocketed instead of going down. It left me sleeping longer. I was cranky and crabby as well. I ran out of the product. I went back to my doctor 3-4 times, and she prescribed another medicine to help lower my blood pressure. I took that prescription and went to Walmart, got a printout of the medication, and decided not to take it. In February, I changed doctors, took the empty prescription bottle with me, and asked him if I needed to take it further. I ran out of the product and was taking an alternative that had Hawthorne extract, potassium, and other nutritional supplements to lower my blood pressure."

3 / 10
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90 Report
  • ban...
  • Taken for 1 to 6 months
  • June 13, 2018

Metoprolol for High Blood Pressure "My experience with this drug was that I was always tired and had no energy. I was told that I had to take the drug once a day, and I took it when I got home after work. My blood pressure skyrocketed instead of going down. It left me sleeping longer. I was cranky and crabby as well. I ran out of the product. I went back to my doctor 3-4 times, and she prescribed another medicine to help lower my blood pressure. I took that prescription and went to Walmart, got a printout of the medication, and decided not to take it. In February, I changed doctors, took the empty prescription bottle with me, and asked him if I needed to take it further. I ran out of the product and was taking an alternative that had Hawthorne extract, potassium, and other nutritional supplements to lower my blood pressure."

3 / 10
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90 Report
  • Anonymous
  • July 23, 2010

Metoprolol for Supraventricular Tachycardia "I love this medicine! It has quite literally saved my life, and has made my life much more livable. Whenever I would do anything physical, my heart would beat so fast that I would frequently faint. I went to my cardiologist, and she gave me a holter monitor. She saw what I was talking about and gave me 50mg of Toprol-XL every day. That was over 3 years ago, still on the same dosage, and it is wonderful. For the first few months, I was a little overtired, but that side effect quickly went away."

10 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.