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Metoprolol and Depression: What Users Say (Page 2)

Brand names: Metoprolol Succinate ER, Metoprolol Tartrate, Toprol-XL, Lopressor, Kapspargo Sprinkle

Reviews for Metoprolol

Commonly mentioned side effects
  • jar...
  • Taken for 2 to 5 years
  • January 5, 2021

Metoprolol for High Blood Pressure "I was placed on Lopressor in the early '80s and was on it for about 3 years. After roughly 2 years, I started to tire easily, lost interest in things in general, my personality and outlook changed to being very negative, and I was diagnosed with clinical depression. Counseling and medications didn't help at all, and it wasn't until my wife saw an article in a medical journal that stated some patients who had been on Lopressor for 2-3 years became clinically depressed. We showed the article to my physician, and he changed me to another prescription. It took about 4 weeks for me to get back to normal. I am now on amlodipine/benazepril, which is working very well for me."

2 / 10
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  • Mik...
  • Taken for 5 to 10 years
  • January 17, 2020

For Supraventricular Tachycardia "(To treat tachycardia, the medicine does a great job at lowering heart rate to normal levels. I would rate it a 10.) To rate the medicine due to the side effects causes lack of sex drive, and as it makes anxiety, depression, and causes you to feel tired like there's no tomorrow. Even if you sleep 18 hrs out of the day, it still doesn't feel like enough, I would rate it a 1 at best.) I have been on this medication for going on 7 yrs. I was started out on a low dose, and now I'm up to 100 mg 2x a day. Now the problem with this medication is it makes you want to sleep constantly, and if you have issues like anxiety or depression, it makes it worse with high dosages."

5 / 10
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  • Ezp...
  • April 18, 2016

For Atrial Fibrillation "Hard to know if it works, I've been on it for two years following surgery, aortic valve replacement, VSD repair, maze procedure. Two months ago I had an Afib episode. When my heart felt off, this medicine helps control the symptoms, but overall, with the combination of losartan and warfarin, I feel tired, depressed, I'm sun sensitive, get unexplained rashes, have a low sex drive, diarrhea... considering it didn't help relapsing, all I want to do is stop using it."

3 / 10
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Frequently asked questions

  • mko...
  • Taken for less than 1 month
  • April 28, 2022

Metoprolol "Used it in connection with Marfan's syndrome. My dose was 50 mg. My heart rate lowered as intended, and it did help with some anxiety symptoms, which was a nice bonus. However, I became tired all the time, I lost interest in my studies, and it also caused slurred speech. After 2 weeks of usage, the 50 mg dose was not working as effectively in terms of keeping my heart rate down. I did not see any reason to keep going, as raising the dose to 100 mg would have probably destroyed my life. My doctor agreed that the side effects would cause long-term damage, and I'm being put on a different beta-blocker now. The medicine is cheap, and the benefits it had in the beginning were really nice, so I wish that my body didn't react so negatively to Metoprolol."

3 / 10
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  • Anonymous
  • February 28, 2022

For High Blood Pressure "Oh my, side effects were terrible. Racing heart, sick feeling, anxiety, depression, tingling hands and feet. Dr. said to stop it and put me on nifedipine 60 mg instead. Wow, what a change, blood pressure down, sometimes under 120/80. Feel like I have my life back."

1 / 10
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  • Met...
  • Taken for 6 months to 1 year
  • February 5, 2022

Metoprolol for High Blood Pressure "It got my blood pressure under control with 25 mg metoprolol. I take it with 40 mg propranolol divided 2 times a day. Must say it helped a lot. Had social anxiety, which has been almost gone away. Sure, it takes a few weeks/months to get into it, at the beginning, I felt depressed, tired, erectile dysfunction (which is easily treatable with citrulline/arginine or Viagra) and got low blood sugar. Now, after almost a year, I have mild side effects but are treatable (tiredness). Have tried before: diuretics, ACE inhibitors, calcium channel blockers, and ARBs, and for me, beta blockers are the best since the other medications had far worse side effects. Something I have to add is I might have POTS (self-diagnosed), and maybe it’s why it works so well for me. My pulse gets from 60 to under 100 bpm without these."

9 / 10
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  • TMM...
  • Taken for 1 to 6 months
  • May 1, 2022

For Atrial Fibrillation "This medication lowered my heart rate to 40 to 50 bpm, which feels too low. I am frequently fatigued, feeling very weak, and trying mild exercise to build strength makes my muscles hurt (because a low heart rate doesn’t get enough blood to my muscles?). I am bloated, and my clothes are getting too tight. I have been on metoprolol tartrate, then succinate, at a low dose - 12.5 mg once daily - for 3 months. I am 70 years old, and even at this low dose, I am very uncomfortable with the side effects. My a-fib was very mild and did not warrant taking blood thinners, and it didn’t seem to be any worse now until a pre-surgery test indicated (…maybe) I may have cardiomyopathy. I am seeing my doctor in a few days. I have to stop this medication because these side effects are making me very depressed."

2 / 10
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More FAQ

  • flo...
  • Taken for 1 to 6 months
  • August 13, 2021

For Supraventricular Tachycardia "I am a 22 y/o woman who was diagnosed with SVT after having frequent, long, and intense episodes of a resting heart rate at 170. This medicine cured me of the high heart rate, but I became very depressed and got anxiety out of nowhere. I felt numb and dead inside, honestly. I was taking 25 mg twice daily of the extended-release kind. I am 6’0, 145 lbs. My doctor is letting me try getting off the medicine. So far, I have felt like a new person and finally feel happy and not as out of it and mentally absent. I took 1/2 the pill instead for each dose and then switched to 1/2 at bedtime. Soon, I will try not taking it at all. So far, so good. This medicine made me almost suicidal and extremely uncomfortable in my own mind, body, and life. I hope things will continue to go well being off the medicine. If not, I will not let myself take the original 25 mg/twice daily dose because that made me feel like a depressed, psychotic zombie."

6 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • September 21, 2021

For Atrial Fibrillation "I have been prescribed this medication, and most all side effects are happening: depression, very sleepy and lethargic, ringing in my ears. My stomach hurts, and appetite not good. I really cannot say what good it is doing, but I really snapped at my wife today, telling her I am done taking this medication. Actually, I will taper off it, as there are severe warnings about abruptly stopping. 25 mg once a day I was prescribed, but originally twice a day, and I informed the doctor of side effects and then went to 25 mg once a day, but I have got to get off this stuff."

3 / 10
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  • gra...
  • June 1, 2009

"I have hypertrophic obstructive cardiomyopathy and take metoprolol twice a day to keep my heart rate lowered and blood pressure down. It does the job well, but the side effects are rough to handle sometimes. Such as dizziness, sleepless nights, daytime drowsiness, forgetfulness, and depression, but I'm still coping after about four years, and I guess on for the rest of my life. But if I can manage after three brother suicides, then so can you."

8 / 10
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  • POm...
  • February 8, 2009

Metoprolol "It's hard for a patient to 'rate' a medication. I have an excellent cardiologist whose job that is. However, I know that Toprol comes with a tendency toward depression for many people, and for me, pre-existing depression has been mildly exacerbated. I also take amlodipine since May of last year, and this is a drug also known to cause/increase depression. I take several other antihypertensive drugs, therefore, it is not easy to tell which is causing what. Welcome to life post-cardiac bypass surgery-a life diminished, trust me, but at least-LIFE."

7 / 10
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  • Ann...
  • Taken for 1 to 2 years
  • May 3, 2022

For Heart Attack "Have been on this drug for two years. My side effects are being tired even after sleep. I have panic attacks, depression, can't stand to be around people, my vision is bad. When I talk, I lose my train of thought. I can remember people's names. I'm lightheaded, dizzy, my hair is falling out by handfuls. I have lost all interest in life as I knew it. The dose I take is 50 mg a day. I guess it may be keeping me alive. I was put on this because of a widowmaker heart attack 2 years ago, then a year ago, I had another stent."

6 / 10
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  • Pam...
  • Taken for 1 to 6 months
  • September 24, 2021

Metoprolol for High Blood Pressure "I'm on 400 mg a day. I have vision problems. There's a black half-moon shape in one eye, sometimes bright colors. I have nausea and fatigue every day, and depression. I can't stop, as it's for a previous aortic aneurysm. Just feel miserable and like I've got the flu every day."

3 / 10
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  • meb...
  • February 22, 2009

For High Blood Pressure "This medicine did lower my blood pressure, but the side effects were horrible. It caused hair loss, skin rash, weight gain, insomnia, tiredness, dizziness, and depression."

1 / 10
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  • few...
  • Taken for 1 to 6 months
  • December 28, 2022

Metoprolol for High Blood Pressure "Been on this for 5 months since the heart stent. Worst 5 months of my life. No energy, dizziness, depression, shortness of breath. This rubbish is absolutely awful."

1 / 10
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23 Report
  • Mgb...
  • Taken for 1 to 6 months
  • November 4, 2020

For High Blood Pressure "Been on this medication for 2.5 months, and it makes me feel bad. Memory lacking, headache, and depressed. Only take 12.5 daily. BP and heart rate low. I guess it's working, but makes you feel sick."

4 / 10
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21 Report
  • mar...
  • May 2, 2010

"Listing the side effects I am having with metoprolol: weakness, shortness of breath, chest pressure at times, and depression."

1 / 10
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20 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.