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Metoprolol Succinate ER and Tiredness: What Users Say

Tiredness: mentioned by 26 users (27.4%)

Based on user experiences from 95 Metoprolol Succinate ER reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

tiredness 27.4%
shortness of breath 15.8%
fatigue 11.6%
chest pain 9.5%
dizziness 9.5%
weight gain 9.5%
depression 8.4%
anxiety 7.4%
insomnia 7.4%
heart palpitations 6.3%

Reviews for Metoprolol Succinate ER

Commonly mentioned side effects
  • Blu...
  • November 18, 2019

For High Blood Pressure "This is the worst blood pressure medicine I have ever taken. It caused me erectile dysfunction, memory loss, and tiredness. It also gives you blurry vision. Stay away from this bad medicine. When I stopped taking this Metoprolol Succinate, my erection got better, I felt much better and more energetic. This medicine will definitely harm your body."

1 / 10
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353 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • July 2, 2020

For High Blood Pressure "I’ve been on metoprolol for almost a year now. I am only 24 and high blood pressure runs in my family. My mother had a stroke from high blood pressure, and my grandfather passed from it. I had high blood pressure with my daughter, but it went away after I had her, and then I had my son and it never went away. I was on bystolic, and it worked great for me, but was too expensive. So, I was put on metoprolol 25 mg, and it didn’t really help my blood pressure. I was prescribed a higher dosage to 50 mg. I am constantly tired, I’ve gained weight, and I am having night sweats. If I don’t take it, my heart starts hurting, and I hate it. The only good thing about it for me is that it does help with my blood pressure and my chest pain."

4 / 10
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165 Report
  • Bsh...
  • Taken for 6 months to 1 year
  • August 16, 2021

For Supraventricular Tachycardia "I can't believe it took me this long to correlate my symptoms with this pill, and I'm a 25-year-old RN. Forty-six years old and have had SVT since my 20s. A couple of years ago, I had a 24-hour stay to evaluate HR of 165. All testing normal. No treatment. A year later, back in the ER with a pulse of 250. I was given Adenosine to convert me and then given Metoprolol Succinate 25mg daily. I've been on it for a year. I noticed some tiredness but nothing major. Over the next year, my tiredness became debilitating, and I suffered severe depression, insomnia, and panic attacks. I didn't make the connection and blamed it on the pandemic and all the isolation and restrictions everywhere. I thought I was just having a hard time. Then the drenching night and day sweats started. Still, I blamed it on perimenopause. But then came the heat and activity intolerance. Minimal activity caused me to become SOB, shake, and be drenched in sweat. Sleep was non-existent. I began having numbness in legs and feet."

1 / 10
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Frequently asked questions

  • Koa...
  • Taken for 1 to 6 months
  • August 8, 2020

For Supraventricular Tachycardia "I was diagnosed with SVT's and put on metoprolol - which has helped a lot with my palpitations. Instead of multiple times per day I now only get palpitations a few times a week. I first started out on 25 mg. in the a.m., but that didn't do the trick. Then went to 25 mg. twice a day, however, that made me extremely tired. Now I take 12.5 mg. in the a.m., & 25 mg. in the p.m. and this works! My resting heart rate has decreased between 55 - 60 bpm. But... everyone metabolizes meds differently."

10 / 10
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  • Roc...
  • Taken for less than 1 month
  • September 28, 2017

For High Blood Pressure "Went to have foot injury x-rayed at urgent care and spiked a blood pressure of 195/110, maybe due to pain. Was given this by IV in the ER, then pills for 3-4 nights at home. It lowered my blood pressure by like 20 points per day, and I was fine for 2 days, but then had episodes of exhaustion to the point where I had to lie on the couch for hours to recover from simple housework like washing pots. Was also short of breath like I had run 5 miles. Swallowing felt weird. Got disoriented while driving. It's a 9 on effectiveness but can't tolerate the side effects. Am 63/F."

9 / 10
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  • Anonymous
  • May 7, 2010

For Atrial Fibrillation "This medication has made me extremely tired. I also have forgotten to do simple daily routine tasks such as setting up the coffee pot at night. One short store trip, and I am exhausted! I will try something else."

5 / 10
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154 Report
  • Anonymous
  • May 7, 2010

For Atrial Fibrillation "This medication has made me extremely tired. I also have forgotten to do simple daily routine tasks such as setting up the coffee pot at night. One short store trip, and I am exhausted! I will try something else."

5 / 10
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More FAQ

  • Fre...
  • Taken for 1 to 6 months
  • July 8, 2018

For Supraventricular Tachycardia "I was diagnosed with moderate/severe obstructive sleep apnea and supraventricular 'events' 4 months ago. I was put on a ResMed PAP machine and Metoprolol Succinate ER 25 mg. I have gained 10 pounds. I feel: no energy, chest heavy, heart pumping weak, breathing decreased/light, affect flat, tired, constipated, I can't think. My events are rare now, but I don't know if my events were due to the sleep apnea and if the PAP helped decrease them because I started both med and PAP at the same time. I miss being extroverted, energetic, and outgoing. I don't know if there is any other treatment available. Ablation? I don't like this med."

5 / 10
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83 Report
  • ban...
  • Taken for 1 to 6 months
  • June 13, 2018

For High Blood Pressure "My experience with this drug was that I was always tired and had no energy. I was told that I had to take the drug once a day, and I took it when I got home after work. My blood pressure skyrocketed instead of going down. It left me sleeping longer. I was cranky and crabby as well. I ran out of the product. I went back to my doctor 3-4 times, and she prescribed another medicine to help lower my blood pressure. I took that prescription and went to Walmart, got a printout of the medication, and decided not to take it. In February, I changed doctors, took the empty prescription bottle with me, and asked him if I needed to take it further. I ran out of the product and was taking an alternative that had Hawthorne extract, potassium, and other nutritional supplements to lower my blood pressure."

3 / 10
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90 Report
  • ban...
  • Taken for 1 to 6 months
  • June 13, 2018

For High Blood Pressure "My experience with this drug was that I was always tired and had no energy. I was told that I had to take the drug once a day, and I took it when I got home after work. My blood pressure skyrocketed instead of going down. It left me sleeping longer. I was cranky and crabby as well. I ran out of the product. I went back to my doctor 3-4 times, and she prescribed another medicine to help lower my blood pressure. I took that prescription and went to Walmart, got a printout of the medication, and decided not to take it. In February, I changed doctors, took the empty prescription bottle with me, and asked him if I needed to take it further. I ran out of the product and was taking an alternative that had Hawthorne extract, potassium, and other nutritional supplements to lower my blood pressure."

3 / 10
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90 Report
  • Tir...
  • Taken for less than 1 month
  • March 11, 2013

For Atrial Fibrillation "I was prescribed Metoprolol for Atrial Fibrillation and found that I was extremely tired. I began taking it at night, but developed terrible constipation. I have Irritable Bowel Syndrome, so the constipation was not good for me."

1 / 10
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112 Report
  • Hop...
  • February 21, 2017

For High Blood Pressure "I was on 50 mg of Metoprolol twice per day and had a few high readings of 200/80 due to anxiety. Doctor raised me to 100 ER twice per day plus Losartan. I feel like a zombie. It has lowered my BP but I have several side effects listed such as dizziness, tiredness, confused at times, dry mouth, burping, and a few other side effects. I have been on this high dose of ER for 10 days, and I don't think I will be able to take this drug in such a high dose much longer. The doctor wants me to go for heart tests to find out why my pressure went so high. High blood pressure runs in my family, and I could stand to lose 20 pounds which I am trying to do."

2 / 10
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79 Report
  • JR4...
  • Taken for 1 to 2 years
  • November 17, 2015

For Supraventricular Tachycardia "I wanted to add on a couple things to my previous review. Everyone warned me about how tired I was going to be since this medication would literally be slowing my heart down but I've never experienced that. I don't sleep much and have insomnia so that could be why. I also have experienced crazy dreams and I sleepwalk from time to time. I've always had dreams and talked in my sleep but I think the medication makes it a little worse especially if you're taking it closer to bedtime. I do get a little lightheaded if I stand up quickly and bend down but it's not bad. The benefit I get from this medication outweighs any of these insignificant side effects. I would recommend to push through any side effects and let the medication adapt to you!"

9 / 10
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87 Report
  • Che...
  • August 4, 2021

For Supraventricular Tachycardia "I hate this medicine! I was having back-to-back panic attacks for five days straight just to find out it bottomed my blood pressure out. The worst brain fog I have ever experienced. My vision was horrible. The dizziness alone was horrific! I couldn’t understand why I had no energy, and panic set in constantly,"

1 / 10
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40 Report
  • Cou...
  • August 25, 2016

For High Blood Pressure "Taking for blood pressure. White coat hypertension. Usually 180/100 with pulse 104 in doctor's office. My anxiety is down. Blood pressure now usually 114/70 with pulse 70. Taking 50mg. Only side effect is feeling very tired. Hopefully, it will go away."

10 / 10
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80 Report
  • Anonymous
  • February 27, 2011

For Heart Attack "Make sure you review your dosage with the doctor. As the others stated, it will make you tired and lethargic. It also has had an effect on my ability to have a discussion without forgetting a word or two. My doctor gave me a dosage of 100mg/2x daily. I wound up back in the hospital due to my heart rate being a low 32 beats per minute. The hospital treated it as a failure with the original stent and went back in to check the previous operation. That was over a year ago. We tweaked the prescription down to 50 mg once a day, but I never got out of the lethargic state."

5 / 10
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89 Report
  • Anonymous
  • February 27, 2011

For Heart Attack "Make sure you review your dosage with the doctor. As the others stated, it will make you tired and lethargic. It also has had an effect on my ability to have a discussion without forgetting a word or two. My doctor gave me a dosage of 100mg/2x daily. I wound up back in the hospital due to my heart rate being a low 32 beats per minute. The hospital treated it as a failure with the original stent and went back in to check the previous operation. That was over a year ago. We tweaked the prescription down to 50 mg once a day, but I never got out of the lethargic state."

5 / 10
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89 Report
  • Rx2...
  • Taken for less than 1 month
  • December 21, 2022

For High Blood Pressure "I’ve jumped around on different BP meds for 2 years now. Took atenolol with triamterene with no side effects for years and years. Switched to propranolol for essential tremors - 2/3 of my hair fell out in 2 months!!!!! I went back to atenolol and my hair continued falling out but not as badly. Taken off triamterene due to chronic kidney disease that was misdiagnosed for several years. Taken off atenolol at my insistence. Put on losartan, which causes sleepiness, so I take it at night. But BP 150-155/80 became the norm upon awakening. So added this metoprolol succinate ER. It’s been 4 days, and I’m exhausted and keep falling asleep. Dr. stressed to give it 6 weeks. Now BP runs much better, except diastolic less than 70. So hopefully my body will adjust. My BP morning headaches are gone, though, so huge improvement there. History of strokes in both grandmothers, high BP both parents. I’m a senior citizen. I’m rating 5 out of 10 for now."

5 / 10
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16 Report
  • Del...
  • Taken for less than 1 month
  • October 11, 2016

For Supraventricular Tachycardia "My doctor prescribed me Metoprolol Succinate ER 25 mg and advised me to take half the first few days. When I did, I began to have a rush down my body, and severe tremors began. My heart rate jumped to 138, it was pounding. I tried laying down, still. I even had chest pain. I usually get low blood pressure, but I only felt very tired, not dizzy or faint. I called my doctor, and he asked me to go to the ER to make sure everything is okay. I did. They did an X-ray, blood work, and gave me IV to flush it out. Everything was normal. My heart rate kept jumping from 67 to 105 suddenly. I was told to stop taking it. I am bummed out because I was looking forward to this helping me. After everything, my heart rate was 54 resting and 72 active. It did afterwards!"

3 / 10
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  • mko...
  • Taken for less than 1 month
  • April 28, 2022

"Used it in connection with Marfan's syndrome. My dose was 50 mg. My heart rate lowered as intended, and it did help with some anxiety symptoms, which was a nice bonus. However, I became tired all the time, I lost interest in my studies, and it also caused slurred speech. After 2 weeks of usage, the 50 mg dose was not working as effectively in terms of keeping my heart rate down. I did not see any reason to keep going, as raising the dose to 100 mg would have probably destroyed my life. My doctor agreed that the side effects would cause long-term damage, and I'm being put on a different beta-blocker now. The medicine is cheap, and the benefits it had in the beginning were really nice, so I wish that my body didn't react so negatively to Metoprolol."

3 / 10
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6 Report
  • Met...
  • Taken for 6 months to 1 year
  • February 5, 2022

For High Blood Pressure "It got my blood pressure under control with 25 mg metoprolol. I take it with 40 mg propranolol divided 2 times a day. Must say it helped a lot. Had social anxiety, which has been almost gone away. Sure, it takes a few weeks/months to get into it, at the beginning, I felt depressed, tired, erectile dysfunction (which is easily treatable with citrulline/arginine or Viagra) and got low blood sugar. Now, after almost a year, I have mild side effects but are treatable (tiredness). Have tried before: diuretics, ACE inhibitors, calcium channel blockers, and ARBs, and for me, beta blockers are the best since the other medications had far worse side effects. Something I have to add is I might have POTS (self-diagnosed), and maybe it’s why it works so well for me. My pulse gets from 60 to under 100 bpm without these."

9 / 10
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4 Report
  • Met...
  • Taken for 6 months to 1 year
  • February 5, 2022

For High Blood Pressure "It got my blood pressure under control with 25 mg metoprolol. I take it with 40 mg propranolol divided 2 times a day. Must say it helped a lot. Had social anxiety, which has been almost gone away. Sure, it takes a few weeks/months to get into it, at the beginning, I felt depressed, tired, erectile dysfunction (which is easily treatable with citrulline/arginine or Viagra) and got low blood sugar. Now, after almost a year, I have mild side effects but are treatable (tiredness). Have tried before: diuretics, ACE inhibitors, calcium channel blockers, and ARBs, and for me, beta blockers are the best since the other medications had far worse side effects. Something I have to add is I might have POTS (self-diagnosed), and maybe it’s why it works so well for me. My pulse gets from 60 to under 100 bpm without these."

9 / 10
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4 Report
  • Tig...
  • Taken for 6 months to 1 year
  • August 14, 2021

For High Blood Pressure "I was prescribed this when I had an hours-long AFib episode and went to the ER. No meds prior to this. Cardiologist ended up prescribing this (25 mg once a day) with Pradaxa. The metoprolol has kept my blood pressure down and AFib episodes are relatively rare now and only short-lasting. So, no complaints so far. I feel much better than I did, although I get tired in the late afternoon. But, this might be due to always having trouble sleeping."

9 / 10
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  • dau...
  • Taken for less than 1 month
  • August 6, 2013

For High Blood Pressure "Only took for 1 week, made me incredibly tired, could not function."

2 / 10
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173 Report
  • Wyk...
  • March 24, 2017

For Supraventricular Tachycardia "I do not like this medicine. I have gained a lot of weight, runny nose, tired all the time, and very bad and crazy dreams."

3 / 10
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74 Report

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