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User Reviews for Mesalamine to treat Ulcerative Colitis, Active

Also known as: Apriso, Lialda, Pentasa, Asacol, Canasa, Delzicol, Asacol HD, Rowasa, Canasa Pac Zaldyon Rowasa Sulfite Free …show all brand names

Mesalamine has an average rating of 6.8 out of 10 from a total of 98 ratings for the treatment of Ulcerative Colitis, Active. 56% of users who reviewed this medication reported a positive effect, while 22% reported a negative effect.

Mesalamine Rating Summary

6.8/10 average rating

98 ratings from 107 user reviews.

Compare all 36 medications used in the treatment of Ulcerative Colitis, Active.

10
24%
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17%
8
14%
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10%
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6%
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3%
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2%
3
3%
2
4%
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15%

Reviews for Mesalamine

Char · Taken for 10 years or more May 2, 2019

Rowasa (mesalamine): “I have had Ulcerative Colitis for 30 plus years, and I have been on multiple meds. Prednisone working the best. But you can't stay on prednisone forever, nasty side affects. Rowasa, Enemas are great for me, I have no mess, no problems at all. They take away the urge to go, and the spasms in my lower rectum. They are a dream medicine. I can actually feel the medicine coating my colon and it feels so much better, when I use these enemas. But you have to be diligent. Stay on your left side all night for the best results so it stays in the correct place. Don't worry about being ashamed to use these, your significant other will understand. Good luck to all.”

10 / 10
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QuisUtDeus · Taken for 5 to 10 years November 4, 2017

Lialda (mesalamine): “I was diagnosed with moderate to severe ulcerative colitis in 2008. I’ve been on all kinds of medication including asacol, 6mp, remicade, humira, prednisone, amitriptyline, Lialada and others. I also had surgery to remove my gallbladder due to stones - which I regret now since I don’t think made any difference with the BMs and bleeding. I finally had good results with Lialda. I used to take 4 pills a day but managed to ween down to 2. I also realized that part of the healing process came from Spiritual healing and mental attitude. The stress from a job played a major role in my flare ups. Prayer helped me spiritually which in turn helped me with my mind, which then helped with my gut alongside Lialda and a less stressful job.”

10 / 10
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Chad11990 September 9, 2014

Lialda (mesalamine): “My doctor switched me from Acacol HD to Lialda after I lost my insurance and needed a less expensive substitute. I was worried because I had grown accustomed to Asacol and did very well on that medicine. After a few days of adjusting to Lialda, with no real problems or side effects (just a little gas during the first 48 hours), I feel fantastic on Lialda. I've been on Lialda for about 5 months now, and feel as good, if not better than I did on Asacol. I have fewer headaches that I did on Asacol and feel great less stomach cramps. Best of all, for me or anyone who is on the go during the day, I now take one Lialda tablet, twice daily (once in the morning, once at night). This is compared to two Asacol tablets THREE times daily.”

8 / 10
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mymyasky1 · Taken for 1 to 6 months September 12, 2014

Lialda (mesalamine): “Starting taking Lialda about a month and a half ago and it took a couple of weeks to start working. As soon as it started working I felt great no more stomach pain, no more blood, no more diarrhea oh finally something that help take the pain away I was shocked at how good it worked. But then I should have known it was to good to be true about four weeks into it. My beautiful hair started falling out in clumps every time I washed it or even brushed it. I mean it was a lot every time I would cry. Also the muscle aches were the worst. I would sit for maybe 10 minutes and go to get up and almost fall over because my legs almost gave out. Other then that it works great for the pain but I can't take the side effects so I'm going to be switching medicines.”

7 / 10
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JenniferL444 · Taken for 1 to 6 months October 14, 2013

Lialda (mesalamine): “I take two Lialda pills every morning..(1.2gm), Lialda helped my stomach pains and bleeding tremendously! I recommend to everyone! It took a good 2 months to really show a big difference but I am so happy I finally found something that helps. It has taken me years to finally find something. Also, Contact your doctor or Lialda because it%u2019s really expensive but you can get their coupon card and only pay $10 a month.”

10 / 10
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PC · Taken for less than 1 month January 16, 2020

Lialda (mesalamine): “In 2009 I developed pneumonitis, pericarditis, pancreatitis, and ARDS after 3 weeks on Lialda. My GI doc told me and the other docs on my case that I probably had swine flu, and refused to consider Lialda as a possible culprit. The early-onset signs that you're reacting to this drug are that your colitis doesn't improve or gets worse. Having 0 experience (this was a first-line treatment upon my UC diagnosis), I trusted things would improve eventually, as the doctor told me to give it a month. But before that month was up, I was in ICU on full ventilation for 2 weeks & had a cup of bloody fluid drained off of my heart. A pulmonologist noted that my lungs looked like I’d "inhaled pure lye" (which I hadn't). Another doctor on my case eventually intervened and gave me a megadose of steroids, which was the only thing that reversed my condition and imminent death. It was a very long, physically painful, and emotionally devastating recovery, something I never should have had to experience.”

1 / 10
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Derew82 · Taken for 1 to 6 months August 11, 2019

“I've encountered ulcerative colitis (UC) at the age of 36. I had symptoms of a bad gallbladder "so the docs thought" did the surgery and 12 hrs later BOOM! The same symptoms occurred. Explosive, painful, bloody diarrhea. Then put on antibiotics for c-dif. Again no progress. So far into 4.5 weeks of my life that were by far the worst. Lost 30+ lbs and couldn't leave my bathroom or couch, my family and I thought I had cancer/dying. Finally after 4.5 weeks and 4 doctors, 3 ER visits and surgery, I finally got a colonoscopy. Loe and behold I've got severe UC, the worst case the doc has ever seen. The whole colon and some look like alien si-fi stuff. Well put on Mesalamine and budesonide and within 7 days my stool is normal 7 out of 10 times, 1 to 2 bowel movements each day and so far no major cramps. I'm going on 5 weeks since I started these and no side effects. So goes to show works for some and not for others”

8 / 10
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hotboxdp · Taken for 1 to 6 months September 1, 2017

Lialda (mesalamine): “Developed UC after I stopped smoking about 10 years ago. Have tried everything including Lialda and Canasa. The only thing that works for me is smoking cigarettes. I've also tried nicotine gum and patch and even E-cigs. Only real cigarettes work. I have to smoke about 5 per day. Symptoms go away after 1-2 weeks. Then I stop smoking. Sometimes the symptoms will come back after a month, sometimes 6. Hate smoking but what's the alternative?”

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Gear July 19, 2018

“Been on this for two months now, absolutely no more. Its terrible. Makes my symptoms worse. I keep being told not to stop taking it, the effects will eventually stop, they don't. Abdominal pain, in areas I've never felt before now not just my lower left side but all the way up under ribs. Terrible swelling, nausea, headaches, dizziness, fatigue, general sick feeling, constipation, bloating, pain every time i eat. I'm stopping this now. It's not helping and even if it did, side effects outweigh the benefit. I was better before starting this rubbish.”

1 / 10
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KeenKitty · Taken for 1 to 6 months March 20, 2015

Lialda (mesalamine): “I have fairly severe Ulcerative Colitis & after 4 months of feeling horrible, tired, bloody diarrhea with the constant urge to go & fear of eating & setting it off again I was finally diagnosed & put on Lialda - 4 pills once a day. At first it caused horrible gas & bloating & took about a week or so to help the symptoms at all but after a few weeks the symptoms were completely gone & the side effects went away as my body got used to the medication. Then about 1 month into taking it I developed horrible cystic acne all over my face, neck, chest, even in my nostrils & ears! My Dr cut the dose in half to 2 pills once a day & within a few days my skin started to clear & heal. I have been on the lower dose for about a month with NO PROBLEMS!!”

9 / 10
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kbbaby March 22, 2016

Lialda (mesalamine): “This drug almost killed me. I started during a flare up in my 2nd trimester. My hair would fall out and kept reporting unexplained protein in my urine at every doc appointment...I lost 15 lbs during pregnancy and was determine high risk. 6 months post term, I started to get severe chills to fever, couldn't eat, had full colitis symptoms...was hospitalized with cardiac distress, severe anemia and dehydration and stage 4 kidney failure caused by Lialda...mayo clinic detected that the protein in my urine was in fact a side effect from the lialda. I was immediately taken off and my creatin and iron levels began to stabilize and my hair stopped falling out.”

1 / 10
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Cassidy · Taken for 2 to 5 years May 5, 2020

“I’m on mesalamine for colitis just wanted to mention the company that makes it will help with the cost I called them directly sent in an application for patient assist I now get it at no cost I work they have different income levels if you are over a certain amount but under a certain amount you pay $50 a month”

7 / 10
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Natural_first · Taken for less than 1 month January 17, 2017

Lialda (mesalamine): “I was prescribed this med for mild UC. I discussed concerns with my doctor on starting a medication while nursing and without trying natural approach to curing the symptoms first. He share some patience had success using turmeric supplement to address inflammation of the sigmoid colon (lower intestine and bowel). After 2 weeks on the Turmeric my symptoms of urgency, cramping and excessive frequency to 'go' subsided. After 3 weeks, I've been having normal bowel movements and no cramping. I am happy with the progress I've made on this natural remedy.”

1 / 10
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sick of ulcerative colitis · Taken for 1 to 2 years September 8, 2017

Lialda (mesalamine): “I was on asacol for 10 years with no flare ups and leading a normal life. Then 2 years ago my insurance (BCBS) stopped covering it. My Doctor changed me to Lialda and I have had a nothing short of continuous colitis hell flare up for 2 years straight. 20 diarrheas a day. Stomach cramps, weight loss, explosive uncontrolled bm. My Doctor refused to write a letter of medical necessity to my insurance company so I could get back on asacol. So I was on continuous steroids which caused diabetes. Finally to the point of starting humira which caused e coli, c diff, nor ovirus. Recent hospitalization which I was able to get back on asacol while in the hospital. Now discharged and unable to get asacol approved for use outside of hospitalization. ”

1 / 10
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no more systoms in Iowa · Taken for 1 to 2 years November 19, 2015

Lialda (mesalamine): “Glad to say , I am no longer taking this product that really never worked anyway. Have no symptoms for 5 years, everyone said I would be taking prescription medication for life. I just change my eating and drinking habits and you to can win the battle. Good Luck.”

1 / 10
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ddive February 6, 2011

Lialda (mesalamine): “I had been in remission for 20 years and then had a flair up like never before. I refuse to take any steroid based medicines due to the side effects and advised my Doctor of that. He started me on 4 pills of Lialda a day and within 1 week all of my symptoms where gone. I am now taking 2 pills a day and remain symptom free with absolutely no side effects. ”

10 / 10
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Sal · Taken for less than 1 month September 25, 2020

Rowasa (mesalamine): “I've had ulcerative colitis for nearly 15 years. I'm on quite a few meds for it and have to do intermittent steroid rounds due to active flares. I've had a few flares this year that have been challenging to get under control... with the usual frequency/urgency, blood in stool, pain/discomfort. I have used canasa suppositories in the past with little improvement. It had been years since I'd used Rowasa - but my doc suggested we try them again ... I couldn't be more thankful. Within days, my pain/discomfort/frequency have already been reduced, with an almost immediate decrease in pain/discomfort. ONE THING TO NOTE: before administering this med, make sure to gently shake the bottle THEN SQUEEZE UNTIL THE AIR IS OUT OF THE BOTTLE. Otherwise it can cause additional gas/pain.”

8 / 10
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Scotlad · Taken for 1 to 6 months February 18, 2021

“After months of gut pain with bouts of severe watery diarrhoea then cramping, I was scoped and found to have widespread moderate UC. Had previous scopes over years for removal of polyps but no signs of anything else in the past, (family history of bowel cancer) Started on Mesalamine 1.2 g daily September 2020- after first month symptoms and pain/ frequency settled felt great apart from occasional bouts of nausea, retching, dizziness and sweating lasting 15 minutes. Since January 2021 having solid motions two to three times daily-no blood but regular lower abdominal cramps and urgency feeling starting to inhibit my lifestyle again. Tried taking Mebeverine but felt worse. Trying to control pain with codeine/ paracetamol in order to go out to work but am semi retired and can organize the hours I do work. Don't know that Mesalamine 1.2 is working as well for me but equally scared to stop taking the medicine and finding myself back at square one.”

6 / 10
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Mercatkitten July 28, 2019

“45 yr female finally diagnosed with UC after months of misdiagnosis told bout of gastroenteritis put on cipro, flagyl, etc. White blood cell count of 24,000 before hospitalized and still misdiagnosed. Had to yes beg for colonoscopy to get correct Dx. Took 50 mg prednisone step down ended 5 weeks ago only on mesalamine now 4 pills 1 x per day. No blood, but still loose/wet small stool "baby snakes", never a clean wipe, severe headaches all day, fatigue, flu symptoms, sore throat, eye inflammation, muscle pain and unbearable teeth pain/pressure. Need blood labs to check kidney and a follow up with GI. May drop to 3 pills see if help with awful side effects especially the crushing headaches the worst as only can take tylenol does nothing. Not sure side effects worth it hope reduced mg helps. PS taking tumeric & slippery elm at night still never solid stool. Always carry wipes but only going 1- 2 X per day so have to pick symptoms tolerate. Don't want to be put on biologics humira or stelara willing to try lower dose first.”

5 / 10
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In God We Trust July 12, 2013

Lialda (mesalamine): “I have Ulcerative Colitis and have been on Lialda for a few years, 4 pills per day. I am in remission. My biggest problem is Urgency and if I can conquer this problem I would be so much better. I have no pain. I eat most foods but stay away from gassy foods such as beans. I found that when I eat popcorn, I have problems. ”

7 / 10
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Michelle · Taken for 1 to 6 months March 18, 2019

“Prescribed mesalamine for ulcerative colitis in Jan this year after two weeks had severe tummy cramps, bloody diarrhea, headaches, fevers, nausea and rashes. Was then put on pentasa after a week and symptoms got worse. Went back to specialist and stopped it all 7 days ago and put on a course of steroids until I go back for my 2 scope in three weeks and third in 10 months. Symptoms have subsided but still experiencing severe tummy pains, extremes diarrhea (especially once the steroids wear off, I'm up all night constantly on the toilet 15 + times) and loss of appetite and nausea. I can't find any information on how long this takes to leave my system and I regret ever starting this medication. Its made my life awful for the last 2 months. :(”

1 / 10
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Anonymous in PA June 25, 2015

Lialda (mesalamine): “I was diagnosed with left-sided UC in May of 2015. My GI prescribed 4.8 grams (4 pills in the am) of Lialda, plus 1 Canasa suppository (1 gram) at night. The suppository was for 3 weeks only. Within 2 weeks, the bleeding stopped, and I no longer saw the remnants of the colon tissue erosions when I had a bowl movement. I stopped taking the Canasa after a week and a half, because I think it was leading me towards diarrhea, and I felt slight rectal pain. There was no noticeable negative effect to me stopping the Canasa dose at that point. I continued to take the regular dosage of Lialda. I had some dizziness the first week or two, but that had since abated. I also noticed acne that I haven't had in many years. No issues with hair thinning.”

8 / 10
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Anonymous September 17, 2011

Lialda (mesalamine): “What a remarkable medicine. I had battled with ulcerative colitis for quite a few years before I decided to FINALLY go to a G.I doctor. I am so glad I did because after my diagnoses I began Lialda and it has been heaven sent. I can now live a normal life, not "fearful" of foods and how they may affect me later. I had quite a few other symptoms (cramping, moderate bleeding, etc) and sure enough they have all been relieved. I take 2 tablets twice a day and have had no side effects :) Or at least not any that I have noticed. I am relieved to know that my future looks brighter, because being in my younger 20's and dealing with this health issue wasn't exactly the most pleasant thing.”

10 / 10
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Jay1983 March 11, 2016

Lialda (mesalamine): “I have been on this medication for the last three weeks and have not noticed any improvement. My symptoms the last 6 days have been at its worse (going to bathroom almost every 2) hours. My doctor told me to keep taking the medication and is putting me on UCERIS. Just took that pill yesterday. Hopefully that pill works cause this disease sucks right, I am so afraid to go out anywhere because I am waiting on when I will have to go to the Bathroom... I'll keep an update of UCERIS is effective”

2 / 10
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BostonBowelBoy · Taken for 6 months to 1 year August 9, 2015

Lialda (mesalamine): “I take Lialda 3.6g each morning which cleared up my diarrhea and bloody stool but I have had neurological side effects of headaches, fatigue, and slow-thinking, and abdominal pain, gas, and bloating as well. I'm too scared to switch to other meds despite an asacol prescription given the risk of flare ups when meds change, but I don't want the mental haziness for the rest of my life.”

6 / 10
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This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.