Medroxyprogesterone and Mood Swings: What Users Say (Page 3)

• 49e...
• Taken for 6 months to 1 year
• July 11, 2015

Medroxyprogesterone for Abnormal Uterine Bleeding "I've only had 3 shots from Dec 2014 to my last one May 2015. After the first shot, my periods stopped completely, no pain, nothing. Also took care of my cyst problems. Used to get horribly large cysts that didn't erupt properly or in a timely manner. So that has been really nice, not having to go through that pain for weeks. Second shot, still going strong, no problems, just a little boob soreness at times. Third shot, here we go - weight gain, lots of hair loss, cramps with bad shooting pain, boob soreness/pain when bending over, brown spotting to heavy brown, which I have never in my life had (I'm 30) for weeks now. Headaches, mood swings - very emotional at times. Going to the doctor 7/22/15, I might just get off the shot. #Listen to your body."

• Anonymous
• Taken for 1 to 6 months
• June 24, 2022

Medroxyprogesterone for Birth Control "The absolute worst thing I have EVER tried in my life. It has made my life a living hell for the past 6.5 months, and I still live in hell. I have gotten 2 shots of Depo and refused to go for the 3rd shot, which was due a little over 2 weeks ago. I have gained 20 lbs so far, and it’s gotten even worse since I stopped the shot 2 weeks ago. Depression, acne, and mood swings are horrible, but the worst of all was the constant heavy bleeding for 5 months EVERY SINGLE DAY! I became severely anemic that I could barely walk for 10 minutes due to extreme fatigue and exhaustion. No sex drive and no desire to do anything at all! Just sleeping half of the day and feeling tired without doing anything. This shot has been the worst nightmare for me. I wish I had done my research before getting it. I now regret it 200%."

• Mel...
• Taken for 6 months to 1 year
• October 16, 2019

Medroxyprogesterone for Birth Control "Read a lot of negative stuff about Depo after getting my first shot, made me paranoid as anything. For me, it's been perfectly fine so far, currently coming up to my third shot. No massive hormonal changes or mood swings, no weight gain, everything is working well."

• sil...
• Taken for 6 months to 1 year
• December 25, 2012

Medroxyprogesterone for Birth Control "During the nine months I was on the shot, I had a constant period, sometimes heavy, sometimes light. I was tired all the time and began to have suicidal thoughts, which I've never had before. I had crazy mood swings and would start crying for no reason at all. I switched to NuvaRing, and all my symptoms have gone away. I know the shot works for many people, but clearly, it's not for me!"

• kat...
• Taken for 1 to 2 years
• November 17, 2015

Medroxyprogesterone for Endometriosis "I've been on Depo for almost two years now and have not had a period since I got the injection. I no longer have the debilitating cramps that I would get each month, which is a godsend. After I'm first given the shot, I have about 5-7 days of being a little more emotional than usual, but it's usually due to my hormones being balanced and changing a little, but it just means a bit of crying and basically how I used to be emotionally before a period. I have noticed that some nights I wake up with a really extreme cramp out of nowhere, but I believe that that might be an issue that's more to do with my hormone levels, etc. Either way, Depo has definitely spared me from weeks spent in bed because of the painful cramps!"

• Cas...
• June 4, 2015

Medroxyprogesterone for Abnormal Uterine Bleeding "I got my first shot April 28th, 2015. My period was supposed to come May 10th and didn't. It was a week late, and I've been bleeding and spotting ever since. I have bad mood swings and get mad over absolutely nothing. I get cramps all day, every day, and it's so horrible. It's been almost 3 straight weeks of bleeding, sometimes heavily and other times just spotting. I don't know if it even protects against pregnancy because you can't have sex if you're constantly bleeding! I would NOT recommend this to anyone, ever. I have an appointment with my ob/gyn on Tuesday, so I hope there is some kind of solution since I have to ride this out till the end of next month!"

• Jay...
• Taken for less than 1 month
• June 11, 2019

Medroxyprogesterone for Birth Control "I would never EVER recommend Depo-Provera as a birth control option to ANYONE!! I had my first shot around 3 weeks ago. I’ve had crippling headaches ever since. Constantly feel sick, mood swings, and the onset of depression is QUICK!! I honestly cannot wait for this shit to get out of my body! DO NOT EVER TRY THIS! Condoms are the safest as no hormones put into the body and will save you a lot of hassle!!!"

• Deb...
• April 30, 2017

Medroxyprogesterone for Abnormal Uterine Bleeding "Awful experience on Depo. Only had one shot - never again. Bleeding non-stop for 3+ weeks. Serious mood changes and anxiety. Total loss of libido! Been to the docs twice, but nothing can counteract it, so stuck with it making me feel lousy till it wears off. Do not recommend this contraceptive to other women. I would rather be sterilized than feel the way I do!"

• moo...
• Taken for 1 to 2 years
• September 6, 2022

Medroxyprogesterone for Birth Control "It genuinely ruined my body. I no longer menstruate, I inadvertently gained 40 pounds. My mood has never been the same, with worsening mental health. I wish I never put this stuff into my body. Good chance that I'm infertile now, despite never having problems with my reproductive system-I used to have very regular periods and a healthy sex drive, now, reduced to nothing. Please, please do yourself a favor and stick to a pill."

• rik...
• Taken for 1 to 6 months
• March 21, 2014

Medroxyprogesterone for Birth Control "I took this shot about 2 months ago and was excited for it. I had read many good things about it, and I am quite a forgetful person, so a shot once every three months was great. Little did I know, though, that it would not be great for me. I had my period for 17 days. It finally went away, but now I have my period again, hoping it won't last 17 days again... Just like a previous reviewer stated as well, I was super energetic and lively, and this shot has made me quite withdrawn and quiet. I really hate that. I also feel myself becoming a little more emotional over small matters that I would laugh at before. This wasn't the birth control for me."

• Net...
• Taken for 6 months to 1 year
• November 1, 2015

Medroxyprogesterone for Abnormal Uterine Bleeding "After I had my baby, my doctor suggested that I get on birth control. The depot is easier to take one every three months. So, I decided to go with that birth control method. I got the depot shot on September 6th, 2015. Come October, I get my period, it's an irregular period. I usually bleed for 3 to 4 days. Now I bleed heavier and longer. It's been 8 days and counting. I'm not due on December 6th for another shot. I'm definitely not continuing this depot shot. I've been depressed, very emotional, moody, and my attitude has changed since I've been on this shot. I constantly argue with my boyfriend. This shot has a lot of bad side effects, but I haven't been feeling like my normal self since I've been on this shot. I wouldn't recommend this shot to anyone. Please go with other options."

• Use...
• March 26, 2015

Medroxyprogesterone for Birth Control "I have been on this shot for 5 years, almost 6 now. I had had no serious problems. I gained about 40 pounds, and I am having trouble losing it, but that is it. When I first got on this, I actually lost weight and was the smallest I'd ever been, but I decided to try to switch to the pill (hated it) and then got back on Depo, which is when the weight gain happened. I had major mood swings, but am now on another medication to help control that. It definitely works, and I love not having a period! Just hate the weight gain. This is definitely a birth control I would recommend."

• pat...
• Taken for 1 to 6 months
• May 24, 2015

Medroxyprogesterone for Abnormal Uterine Bleeding "Worst decision ever!! Got the Depo shot after 6 weeks postpartum, thinking it was the most convenient birth control method. Oh, so wrong. Got it 4-17-15, started bleeding 5-1-15, a month after I am still bleeding. Limited sex due to period bleeding, it's not pretty. Terrible mood swings. Increased cravings for sweets and junk food, dizziness, very tired and sleepy. Well, it's a horror story. I am not going back for a 2nd shot, no way. I will never get another shot of this medicine that transformed me into a nonstop bleeding witch."

• Car...
• October 26, 2016

Medroxyprogesterone for Abnormal Uterine Bleeding "I took the 3-month Depo shot in May this year. I have been bleeding nonstop for the last 5 months. I have been to the doctor twice and been given tranexamic acid and taken the entire two boxes to no avail. This week, the bleeding has gotten so heavy that I'm soaking through tampons in less than 3 hours. I'm taking iron tablets and folic acid so that my body doesn't crash. As for sex... that's out of the question, so I don't see a point of this form of birth control. I hate Depo. I hate how I had a normal and very regular cycle, now I'm a mess of mood swings, craving junk food, gaining weight, and I hope this strain doesn't compromise my relationship with my partner. Never use this drug, it will mess you up."

• The...
• Taken for 1 to 6 months
• October 15, 2013

Medroxyprogesterone for Birth Control "I've been on Depo-Provera for about 6 weeks now. As for my period, it's been amazing. I haven't gotten my period once, and I've gotten spotting once, and it lasted around 2 seconds. Unfortunately, about once a week, I get excruciating migraines to the point where I can't see. Also, I am having such bad hair loss, I'm starting to get worried. I'm also finding some foods I love are making me nauseous, and I've become slightly claustrophobic. The worst of all, though, are my constant mood swings. I am constantly mad over nothing at my boyfriend. Almost every other day, I seem to get really mad out of nowhere. It's like I'm not myself. Depression isn't really an issue, but it comes with my mood swings. I also have no sex drive whatsoever."

• Jan...
• August 17, 2017

Medroxyprogesterone for Abnormal Uterine Bleeding "Had only one shot. I was spotting for 3 months every day, experiencing cramps, dizziness, nausea, and mood changes. I never took another shot, yet I am still spotting and I still have abdominal pain, irregular bleeding, and my mood is changing rapidly. I would never recommend this product to anyone. What's more, I think it should be taken off the market immediately."

• Nic...
• Taken for less than 1 month
• December 9, 2019

For Amenorrhea "I started taking Provera because I didn't get my period for 2 months, and I was spotting off and on. My OBGYN prescribed me Provera for 14 days. Two days after finishing this prescription, I started my period, and it has been extremely heavy. I'm now on day 7, and it's still heavy (changing pads every 2 hrs). I haven't ever in my life experienced this, even after childbirth. After reading other reviews on withdrawal bleeding, I guess I will give it a few more days, but honestly, I was thinking about going to the ER. I am also experiencing mood swings. I just wanted this to be over with. Has anyone else had extremely heavy bleeding?"

• Kit...
• Taken for 6 months to 1 year
• August 27, 2020

Medroxyprogesterone for Birth Control "I was on Depo-Provera for about nine months. I would bleed consistently for a month and a half... consistently. The other month and a half would go by fine. Sometimes the bleeding would start at the beginning month and a half, and sometimes it would start at the ending month and a half. This caused me to get so many bacterial infections (my doctor said the bleeding was throwing off my pH). I was cranky and depressed for no reason. Yes, it did prevent me from getting pregnant, but the side effects I could not deal with!"

• Mid...
• October 28, 2019

Medroxyprogesterone for Birth Control "I started Depo Sep 30. Three days after I finished my cycle, it’s been about one month, and my periods completely stopped. I did not gain any weight, but I also eat very healthy and hit the gym six times a week. I do, however, feel the mood swings and sudden spikes in sadness on random days."

• kma...
• Taken for 1 to 2 years
• July 1, 2013

Medroxyprogesterone for Birth Control "Been on this for about a year and a half. I actually do like it because it's convenient, and you only have to get it every three months. I, however, have gained about 25 pounds. It makes you want to eat everything in sight and makes you an emotional being. It did not mess with my libido, which is a good thing. I don't get my period, just usually spotting about two weeks before I'm due for another shot."

• Sic...
• Taken for 6 months to 1 year
• May 30, 2015

Medroxyprogesterone for Abnormal Uterine Bleeding "I loved the idea of taking one shot and not having to deal with pills. The birth control pills never worked for me, they made me sick and did not prevent pregnancy. I've had four shots so far, the first one was great, I had no period for the first month, but then the second month I had heavy bleeding and what my doctor described to me as 'my vaginal wall falling out of my body.' It was horrifying, I will spare you the details, but needless to say, it scared the crap out of me. I continued with my shots, listening to my doctor, she told me that my body just had to get used to the shot. I'm due for a shot next week, and I've decided to go without. The shot has caused me mood swings, bleeding uncontrollably, etc. No more Depo!! It's horrible."

• Tzh...
• Taken for 1 to 6 months
• January 6, 2020

Medroxyprogesterone for Birth Control "I got the Depo shot again after being off birth control for 8 years. The doctor talked me into it, although I warned her I go crazy. By crazy, I mean extreme mood swings, severe depression, and suicidal thinking. I thought, okay, maybe now that I'm in my 30s, birth control would be different. I am the same person I was when I was a teenager. Depo and all hormonal birth control cause severe mental health issues for me, my mother put me on birth control as soon as I hit 15. Soon after, I was diagnosed and put on various psych drugs. It took many years to believe in myself and stop listening to doctors that hormones don't cause issues that severe. Well, they do. And I made the mistake of trying it again. I won't be getting my next shot this month. Do the rhythm method, ladies. Hormones are a disaster for your mental health and your body."

• Dep...
• December 27, 2018

Medroxyprogesterone for Abnormal Uterine Bleeding "Worst thing I've ever done in my life while only trying to do the right and responsible thing. Now I wish I had done more research before I took the shot. I don't understand. I have been bleeding for 8 months straight, not one day off. It is heavier, more than light, the blood clots are huge, and I can't get pregnant because I haven't had sex in 7 months due to the bleeding. The cost of the pads, diapers, plugs, whatever you want to call them, is so ridiculous. I'm now on iron pills and vitamin C, as my iron levels are so low I am borderline for a blood transfusion. A normal count is 12.5, mine is 7.5 - under 7 you need a transfusion. My mood is horrible, and it's affecting my marriage, my job - hell, even strangers. I am not a nice person, and it's killing me, literally. DO NOT get this shot. It's a real-life nightmare that has no end in sight."

• Mad...
• Taken for 1 to 6 months
• March 2, 2019

Medroxyprogesterone for Abnormal Uterine Bleeding "From the day I started the Depo, til this second, I have not stopped bleeding. I’ve been on the Depo for 5 months and not looking to take the 3rd round. It’s affected my mood, it’s affected my sex drive, it’s affected my relationship, and it’s affected the way I feel about myself. It’s always heavy bleeding, and when I finally feel like it’s going to stop, it gets worse. I’ve ruined every pair of underwear I own. I feel so gross and disgusted with my body that I don’t even want to have sex, and my partner’s been understanding, but it’s hard for him as well. As soon as I wake up, I just want to go back to sleep and always wake up in the WORST mood, which affects my relationship with my partner and family. My doctor recommended getting the Depo, but then wouldn’t see me for medication to stop the bleeding, he has the nurses help me when I’m there. I DON'T recommend the Depo at all."

• Vic...
• July 26, 2019

Medroxyprogesterone for Birth Control "I’ve been on the Depo-Provera for 7 months, and I haven’t stopped bleeding since. I’ve actually lost weight rather than gained any. I’m 20 and weigh 109 lbs when I got the shot. Now I’m 21, weighing 93 lbs. I know I’m eating, but my appetite just isn’t as normal as it was before. When I first got the Depo shot, I didn’t bleed for a good bit, it felt like I was backed up, and my tummy felt bloated, and I just felt sluggish. A month after I was supposed to get my period, BAM! I started bleeding and am still bleeding now. I’m experiencing heavy periods and horrible cramps. Besides the long, agonizing period pains and stains, I’ve also dealt with eerie mood swings and depression, I’d really feel so many emotions in one day. I stress so much over things that can be fixable, and I jump the gun a lot too. What I’m saying is I don’t feel like myself at all. The Depo-Provera can affect people in different ways, but for me, I probably won’t go back to get my 3rd shot, which is this August."