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depo-subQ provera 104 and Mood Swings: What Users Say

Mood swings: mentioned by 4 users (11.4%)

Based on user experiences from 35 depo-subQ provera 104 reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

bleeding 31.4%
weight gain 31.4%
spotting 20.0%
cramps 11.4%
mood swings 11.4%
sexual dysfunction 11.4%
irregular periods 8.6%

Reviews for depo-subQ provera 104

Commonly mentioned side effects
  • Meg...
  • April 5, 2015

For Endometriosis "I started my first injection over a month ago for my severe endometriosis. The day after, I started noticing terrible mood swings, as did my family. I would get angry and freak out at the tiniest things. Usually cry over nothing. It lasted for about 4 weeks, and my moods have simmered down, but not as much as they should. He said to consider Zoloft because my hormone levels aren't normal, and I have anxiety. I have been spotting every day for the whole month and still notice some pain, but not as bad as it was before I started the injections. My ob-gyn said this was normal and assured me after the third injection this would go away. Hopefully, it does. I can now say I'm not living in hell 12 times a year."

7 / 10
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  • Ano...
  • April 17, 2014

For Birth Control "Just recently have gotten Depo subQ Provera for the first time-(at the same time my best friend has gotten the regular Depo-Provera shot)-I haven't had any side effects: no mood swings, no weight gain, nothing. While she's had some mood swings going on. I don't know if it's because it's a different Depo or just because I'm a different person, but I'd recommend this to people. Plus, it's a much smaller needle that goes in your stomach instead of your arm."

10 / 10
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4 Report
  • Kim...
  • Taken for 1 to 6 months
  • March 21, 2019

For Birth Control "I will never take this depo-Provera again. I had mood swings, major depression, crying, and nausea. I have finally gotten my period back, it took about 2 months and 4 days after the injection for my period to finish. I do not recommend taking this drug."

1 / 10
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0 Report

Frequently asked questions

  • Emm...
  • January 18, 2018

For Birth Control "I loved it. I was on it a little over 2 years and have just stopped at the suggestion of the doctor due to the bone loss. I am struggling to find another birth control that could ever be as good for me personally as this one. I didn't have a period unless I was in my window for another shot (every 3 months). There were times where there was light spotting, but nothing bothersome. No cramps, mood swings, and no weight gain that I can tie to it. I hope I can find another that works so well with my body."

10 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.