Latuda and Nausea: What Users Say (Page 2)

• Ano...
• July 30, 2017

For Bipolar Disorder "I used to take it at bedtime, but was getting nauseated. I switched to taking it with dinner, and the nausea has subsided quite a bit. I've gained weight according to the scale, but that's due to constipation the last couple of weeks. My stomach is sticking out more, but I've actually lost a couple inches everywhere else since being on the meds. Constipation was already an issue for me, so I don't blame the meds for it. Overall, it's been great. I'm not angry all the time anymore, no more yelling or crying, no binge eating, etc. I'm a lot happier and more motivated to do anything and everything."

• bur...
• January 14, 2012

For Bipolar Disorder "I've been on Latuda for several months, recently increased to 60 mg. At first, I thought it was pretty good, subtle improvements. Now it's hard to say. I have intense intrusive thoughts every day, suicidal, and I've begun hearing music in the distance (like tinnitus, but music instead of ringing). The former two existed to some degree before I started Latuda, the latter is brand new. Most noted side effect: EXTREMELY sedating for 2-3 hours abruptly followed by intense restlessness, need to move. Haven't figured out a good time of day to take it for this reason. Take it in the morning, I'm fighting drowsiness half the day. Take it in the evening, I'm wide awake until 2 AM. Also, nausea. Other medicines I take: Lamictal, Prozac, Cardizem, Ativan."

• Tan...
• Taken for less than 1 month
• September 25, 2015

For Bipolar Disorder "I have been battling bipolar for the majority of my life. At one point, I was on 8 different medications: Lamictal, Depakote, Seroquel, Elavil, Neurontin, Propranolol, and a couple I can't think of. My most recent doctor got me down to 3, the main one being Lithium. I began Latuda on 20 mg for a week, and now I'm on my 4th day at 40 mg. Today is my second day with adverse side effects... extreme nausea, loss of appetite, and diarrhea. I trust this will pass as it did the first few weeks with Lithium. I have to say that I'm loving the med otherwise. I'm quicker to smile and slower to anger... I nearly feel in control. Make sure you take it with food and expect to be less than 100% for a couple of weeks."

• Win...
• May 3, 2019

For Bipolar Disorder "Because of Latuda, I now have side effects of constant restlessness. I'm always sleepy, I have uncontrollable facial movements, teeth grinding, blinking excessively at times, very dizzy a lot of the time and lightheaded, lots of nausea and vomiting, major loss of appetite. I lost 40 lbs, inability to keep still most of the time, agitation, blurred vision, no sex drive, confused, dry skin, stiff neck, I can't turn all the way, twitching uncontrollably of my eyes, mouth, tongue, face, arms, legs, lips. My back is always sore, my anxiety attacks are worse. I'm hyperactive, I feel manic all the time, always feel nervous. I have tightening of my jaw and snapping, and I even chipped a tooth. Constant headaches, back lower skull always tense, trouble collecting my words, weird jerking movements from my fingers, toes, arms, legs, face, lips, mouth, tongue, and eyes. Unsure of what to do next, restless, confused, looking for something to do constantly. I always feel weak, sweating of my hands and feet. And it won't go away!!"

• Jil...
• Taken for 1 to 6 months
• February 17, 2019

For Bipolar Disorder "I started on Latuda 4-5 months ago for bipolar depression. I feel so much happier now. I used to get up, go to work, and then go to bed. I would stay in bed on my days off. After Latuda, I was able to get up and clean my house; I started going out with my friends again. It has been the only light at the end of the tunnel since 2012. The downsides include horrible, daily, all-day nausea. It is not controlled by Zofran. In the beginning, I would throw up unexpectedly-that has stopped. I do clench my jaw terribly and have very slight weird tongue movements. The tongue movements are pretty much controlled by taking Benadryl at night with the Latuda. Initially, I took Latuda in the morning, but it made me very, very tired to the point I was missing work. All in all, for me, the good outweighs the bad with this drug."

• Rea...
• Taken for 6 months to 1 year
• October 29, 2012

For Schizoaffective Disorder "There are a lot of nausea experiences out there with Latuda. I am trying to post my findings everywhere. I have run a controlled experiment over the course of 4 months to see what I could do about the nausea. Ever read the entire black label sheet that comes with this? I have. It's incredibly intense. One thing to keep in mind is what sorts of foods and drinks (and herbs) interact with the CYP3A4 enzyme that processes the medicine. If you are eating things that do, you could be in for the spins, or insomnia, or worse. Another thing is that you must eat 350 calories with Latuda. Take the dose no earlier than 30 minutes after you eat, and you will feel much better for it."

• Anonymous
• September 6, 2012

For Bipolar Disorder "Some nausea, severe vomiting when I first began... better now. It knocks me out pretty quick, so I take it at night along with 300 mg of Lamictal and 150 mg of Trazodone. The worst side effect I've noticed is extreme fatigue. I can't seem to get enough sleep. Otherwise, it's definitely a step in the right direction. Two weeks and counting - if the fatigue thing doesn't let up, I'll probably have to stop it and move on to something else (it's that bad). Also, curbs my appetite considerably."

• Ann...
• April 18, 2015

For Schizophrenia "I have suffered for 8 years, been hospitalized and tried many different meds, with side effects varying and different levels of therapeutic results for my schizophrenia/bipolar disorders. A few months ago, I had a severe schizophrenic episode, was hospitalized, and went from a high dose of Seroquel to a high dose of Abilify. Once home, I experienced severe muscle spasms, insane restlessness, and weight gain. I knew I could not tolerate the medication, but I wasn't stable enough or even completely to a good baseline despite the high dose. My doc introduced me to Latuda, and it was a miracle pill almost immediately. My weight continued to creep up on it, but that is my only complaint. I take 20 mg with no nausea or side effects."

• The...
• Taken for 2 to 5 years
• July 16, 2024

For Bipolar Disorder "I will be honest. Starting this medication sucked. I always felt sick and nauseous. I never wanted to eat, I got dizzy to the point of almost falling over. I was also taking buspirone 3 times a day with it. I went from 250 lbs all the way down to 160 lbs in the span of 6 months. I could barely carry a grocery basket, I was so weak. But then my mania stopped, my depressive episodes stopped, and I stopped overthinking. My moods were stabilized, I stopped being angry and irritated all the time. Then my stomach issues cleared up, and I could eat again. I ate, I mean I ate. I went from 160 to 280 in a span of a year, I am not even being sarcastic. I really don't know if it's because I no longer feel excessive worry about what I eat. I'm on my way to losing weight now. I'm now losing weight again at 255 lbs and 6 ft 1. Still heavy but not so bad. I guess what I'm trying to say is it took time, it was hard but I stayed consistent. I improved! (Take with food before bed so you don't get sick! With 350 kcal)"

• rda...
• Taken for 1 to 6 months
• December 16, 2019

For Bipolar Disorder "This medication Latuda is the ONLY thing that has worked for my depressive episodes in bipolar disorder. I thought I was treatment-resistant because I'd had terrible luck with psych meds, and nothing else had had any effect on my mood or thinking (aside from anticonvulsants having a horrific cognitive dulling effect on me), but this lifted me out of depression at 40 mg instantly (20 mg had no effect). Decided to stop taking it after about 3 months due to nausea and restlessness caused by it (not severe enough to call it akathisia though), but I will not be afraid to return to it if I ever need to get out of a depressive episode quickly."

• LaL...
• September 19, 2015

For Bipolar Disorder "Do not take this medicine without food! I cannot stress this enough! I forgot to take my meds with dinner tonight and remembered several hours later but forgot that I had to eat while taking it. Less than 5 minutes after taking it, I became extremely nauseous and had to force myself to not throw up. It causes nausea anyway, but this was awful. So always eat something with this medicine."

• Anonymous
• May 21, 2012

For Bipolar Disorder "I started Latuda after being on risperidone for a couple of months. Latuda has gotten better and better. Much less anxiety, more focused, less drowsy. I exercise a lot now too, which I think helps a lot, though. The only thing is it makes me a little nauseated right after I take it, which is before bedtime."

• ReR...
• September 11, 2019

For Bipolar Disorder "I switched from 800 mg Seroquel to 40 mg Latuda. At first, it was okay, but Latuda does NOT sit well with me. Once I finished the taper of Seroquel, the Latuda side effects came out. 1: extreme insomnia: trouble getting to sleep and staying asleep. 2: restless leg syndrome, my legs hurt ALL the time. 3: nausea to the point where it would wake me up in the morning. 4: just general restlessness, it felt like my mind was always running, and I couldn't rest at all. Tapering down off it was also AWFUL. Going from 40 mg to 20 mg, my body felt like it was shutting down. I had to take time off because I could barely walk, I was so nauseous, I was exhausted but couldn't sleep, my vision was swimming, and I felt like I was going to pass out any second. This went on for 2 days of torture and then became survivable enough for me to go back to work. Still suffering through the nausea and exhaustion and hoping that it will go away soon so I can finish off the taper."

• Har...
• Taken for 2 to 5 years
• June 22, 2023

For Bipolar Disorder "The withdrawal is horrific if you already have akathisia. One of the biggest side effects is akathisia, and no one talks about it. I had akathisia from coming off meds cold turkey. Before being put on Latuda, I was rapidly tapered off all my meds and given no time to adjust. The guy started Latuda along with another cocktail. I’ve been diagnosed as bipolar with depressive episodes. I’ve never been psychotic or had mania or even hypomania. The doctor tapered me too fast off Latuda, and now I have all kinds of issues. New symptoms include grinding of teeth, jaw clenching, cracking jaw, flu-like symptoms, nausea, vomiting, muscle aches, muscle twitches and spasms, itching, headaches/migraines, diarrhea, irritability, fatigue, chills/sweats, brain fog, and more. My symptoms of akathisia and insomnia are unbearable now after being tapered too fast."

• Anonymous
• Taken for 1 to 6 months
• March 24, 2022

For Bipolar Disorder "I've been on Latuda for 3 months now. I take it at nighttime and usually I can't sleep! In the morning when I wake up, I have such little energy, and my blood pressure is so low. I still get nauseous. I feel extremely restless. I don't feel like myself at all."

• Joh...
• August 18, 2018

For Bipolar Disorder "Great medication, should be noted that all of those who are suffering side effects such as nausea or akathisia are suffering needlessly, as there are multiple medications that resolve those effects quickly and are not very taxing on the body. Zofran 30 minutes before taking medication for nausea, cheap and effective, just ask your doc for a script. Plenty of people who take Latuda use Zofran in conjunction and do just fine. For akathisia, either Cogentin or Propranolol will resolve it quickly and effectively with little side effects. I have used Latuda for over 3 years now, and there is no better, highly recommend this med, as nothing else has worked even close to as well. Most importantly, for those complaining about weight gain, they must watch what they eat or workout, as I have LOST tons of weight since the switch from Geodon to Latuda years ago and have kept it off."

• nes...
• Taken for 1 to 2 years
• November 8, 2015

For Bipolar Disorder "I take 20 mg of Latuda in the AM with 450 mg of Wellbutrin, and at night I take 60 mg of Latuda with 150 mg of Trazodone, 60 mg of Inderal, and 1 mg of Clonidine per day as needed. Latuda has changed my life-no more racing thoughts. No more bugging out in public or on people. Just have to eat with food because it does make me nauseous. I recommend this for young adults who are manic or have a personality disorder."

• Wen...
• November 20, 2015

For Bipolar Disorder "I have been dealing with mental health issues since I was about 19 years old and am 45 now. I have been on numerous medications, too many to count, and I started taking Latuda about 3 weeks ago. I also take Trileptal, Lamictal, lithium, Prozac, and Vyvanse, and I can't begin to tell you how much better I feel. It just amazes me. I haven't snapped at anyone in a couple of weeks, my mood is the most stable it's been in 20 years. I actually like to be around people again. I'm not full of hate and anger. I have dealt with some serious nausea, vomiting, and headaches, so it is very important to eat at least the recommended amount of calories, and it's much better if I take it at night. I am very grateful I was willing to try Latuda. Thank you."

• Cou...
• Taken for 1 to 6 months
• July 18, 2017

For Bipolar Disorder "I was on Seroquel for quite some time and really liked it, but I didn't appreciate the small weight gain or my lack of desire to wake up in the morning. However, it stabilized my mood and gave me the best sleep of my life. My doctor suggested Latuda, which I've been taking for about 5 months now at 60 mg. Latuda is also great at stabilizing my mood and no weight gain, but it makes me terribly sick. I'm very nauseous even when I have food in my stomach-sometimes to the point I'm sure I'm going to vomit. It even makes my teeth hurt initially. I want to love this medication as it is truly helpful in mood stabilization, but the induced sickness every time I take it is getting old."

• Kat...
• Taken for 1 to 6 months
• August 25, 2015

For Bipolar Disorder "I've been on this medicine for 2 months now. They upped my dosage every week as follows: 20 mg, 40 mg, 60 mg. I went to my check-up, and I still felt very irritable and mean, so she bumped me to 80 mg and said that should work. No! I hated it! I felt like I was jumping out of my skin, I couldn't sit still and felt so antsy that I couldn't sleep. I had to drink a beer or take a Xanax to fall asleep. I decided to take matters into my own hands and dropped myself back down to 40 mg, and I feel great now. I have no depression, and I feel alive again. My anxiety is still here, but I will be back on my Klonopin soon to help. I have to take this with dinner, or I feel nauseous."

• Mcd...
• July 22, 2017

For Bipolar Disorder "Glad works for some. I had nausea, vomiting taking it with food. Panic attacks with racing heart rate, which I've never had before. Muscle dyskinesia of jaw. What made it worse was because it wasn't helping my depression, my psych kept upping the dose 'to see' if that worked. Worst drug I've ever been on & hope your caretakers pay attention to your side effects."

• All...
• Taken for 1 to 2 years
• October 1, 2018

For Schizophrenia "I hate Latuda medication. I've been on this drug for about a year now. I started getting nauseous when I first started, now I'm getting vomiting and diarrhea every day, getting worse. I've been and had blood tests and an ultrasound on my stomach, nothing physically wrong with me. I advise anyone considering taking Latuda should think twice about side effects like mine. This experience is so serious I can't believe they invented a medication that mucks up your physical health. Cheers."

• jus...
• July 5, 2012

For Bipolar Disorder "I am honestly not sure how to rate this medication, but I can relate my experience so far. I have had no nausea, it does help me sleep better. I was given the medication for bipolar. I have been emotionally shut down for a long time, and after 3 days, it has opened up my emotions, and I am not sure if that is a good thing or a bad thing. In February, my husband died of an accidental cocaine overdose. The only emotion I have felt since he died is anger. Now I feel overwhelmed with grief, and I am just not sure how to deal with that."

• Fil...
• Taken for 6 months to 1 year
• January 25, 2017

For Bipolar Disorder "Latuda is the first antipsychotic I've taken, and I have to say it works. Yeah, nausea sets in if you don't eat with it, but it's been pretty fine. Started with 20 mg for the past 6 months, and auditory hallucinations diminished at least 90%. Anxiety about 60%, which is why I'm looking to up my dosage to 40 mg along with upping my Zoloft dosage to 100 mg. But with any medicine, there are side effects, and diarrhea is an issue with this medication. So, with my uptake in dosage, hopefully, I'll be all the way me again."

• JML...
• Taken for 1 to 6 months
• August 30, 2016

For Bipolar Disorder "Bipolar 2 cyclic. Started with Seroquel, Lamictal, and Vyvanse. Seroquel worked but horrible side effects: urine retention, daily headache, all-day-long nausea, weight gain 22#. Despite watching diet and daily swim. Started Latuda. Took 40 mg at dinner (8 pm) for 4 weeks. What a great mood stabilizer for me, but still having periodic days of mania and depression. Increased to 80 mg. Doing great. Within 3 weeks of starting Latuda, lost 20 lbs (almost like my metabolism kicked into overdrive) after being on Seroquel. Side effects: my stomach is super sensitive, so of course nausea. I must take 1 hour after dinner, letting food digest, no alcohol. Otherwise, vomiting within 2 hours after taking. I take RX Haldol 0.5 mg BID and Zofran ODT for breakthrough nausea."