Latuda and Irritability: What Users Say (Page 2)

• Cha...
• June 27, 2013

For Bipolar Disorder "I've been taking Latuda 40 mg once a day in the evening for 1 month for bipolar. I had been on various meds throughout my life for depression, which started when I had postpartum with both my children. I am 45 now, and my children are 17 and 14. I was on Lexapro for depression for quite some time, that seems to have run its course with me. Oh, I was diagnosed with MS in 1992, so add that piece to the puzzle. As far as Latuda, I have mixed feelings. It seems to help me with focus and cognitive deficiencies, which could be MS related. Depression is there, but not as it was, I still cry and, at times, stay in my head too long. I seem to be more agitated with my children. Ativan helps with anxiety when needed. I will be seeing my psych tomorrow to discuss."

• sri...
• Taken for 1 to 6 months
• January 20, 2016

For Bipolar Disorder "I was looking forward to trying Latuda, however, in the month that I took it, the side effects were too much for me. I could not sleep, I was restless, irritable, argumentative - basically not pleasant to be around. And it made my muscles ache so badly I could hardly walk. It wasn't for me. Good luck!"

• Anonymous
• Taken for 1 to 6 months
• July 26, 2015

For Bipolar Disorder "I have taken this med twice in the past few years. Because of ECT, I couldn't remember my prior experience, but for some reason, I was taken off it. I remember now. I experience crippling nausea and irritability. It makes me mean. Also, within 15 minutes of taking it, I'm so sick I have to lie down. I'm going to ask my psychiatrist to take me off it. I just can't function with so much nausea. :("

• Com...
• January 30, 2019

For Bipolar Disorder "I was recently put on Latuda while an inpatient at a clinic to complement my Lamotrigine/Seroquel mix, as apparently it has good evidence they work well together. I lasted just one week. I know Latuda can work wonders for some people, so don't let me turn you off trying it. Although for me, it was terrible. No physical side effects, only terrible emotional effects. I had extreme anxiety, restlessness, irritability, and intense anger... also increased suicidal ideation. I was completely out of character while on it and even felt 'loopy.' It took a week to realize it was the Latuda causing it. As soon as I went off it, within two days of stopping, the emotional side effects had subsided, and I am back to normality with my Lamotrigine/Seroquel combo."

• I...
• June 19, 2016

For Schizophrenia "I have been taking this medication for 2 years now. The first year, it worked like a wonder pill. Minimal side effects such as nausea and drowsiness after ingesting it. Sometimes I would have a feeling of impending doom, like if my life was going to end after I took the pill. Later, this medicine turned out horrible. I don't know what a night's sleep is. It causes me severe insomnia. I feel always tired, even after sleeping 15 hours. I'm suffering from severe depression from this medicine. It makes me irritable and angry. It drains me of motivation. The only thing I can say good about this medicine is that it has caused me no weight gain whatsoever. This medication drains me from being able to live life."

• BiP...
• Taken for 1 to 6 months
• December 10, 2016

For Bipolar Disorder "I started Latuda after being on Abilify since 2004. I was taken off Abilify because I began vomiting every day and had severe rashes after being on the drug for about twelve years. Latuda is horrible! Mind you, I haven't actually had a serious psychiatrist sit down and actually understand my symptoms or who I am in about five years... seems as if that is nonexistent in my region or something now? I developed severe migraines on Latuda and have had more frequent seizures on this medication. The doctor I have seen one time this entire year doesn't want to work with me even though he even noticed I am extremely agitated and annoyed all the time on this medication. I used to be very calm and easygoing; however, now everything irritates me."

• spr...
• April 23, 2013

For Bipolar Disorder "I have been taking Latuda 80 mg for 8 months and am on no other medications for medication-induced bipolar disorder, which was caused by antidepressants prescribed for anxiety. Latuda should be taken with 350 calories, but when I took the medicine with food, I was completely engulfed in anxiety within an hour. Now I take it at night with no food. I sleep for 12 hours at night and feel pretty good but am easily irritated. I had the genetic testing, which indicated that I may be a rapid metabolizer of this medicine, so I'm not sure if I am not getting enough of the medicine (because I am not taking it with food) and that is the cause of my irritability or if 80 mg is causing irritability."

• Wil...
• December 29, 2015

For Bipolar Disorder "I've been taking Latuda 40 mg for almost 2 weeks. I was feeling less depressed, my mood had stabilized, but I felt a lot of anxiety, more than before I started the medicine. Looking back and thinking about where I am today: irritable, angry, and feeling confused. I may be having a manic episode that the medicine may have induced."

• mz ...
• June 14, 2015

For Bipolar Disorder "40 mg Latuda makes my arms hurt. Makes me feel high, like a zombie. Take it at night only. I've been getting a little snappy towards people. I take Trazodone 150 mg at night to sleep. I also take hydroxyzine 25 mg as needed for anxiety. Bipolar I diagnosis. I hate meds..."

• Tor...
• Taken for 1 to 2 years
• August 22, 2019

For Bipolar Disorder "Absolute life changer. Was on 600 mg of Seroquel, 200 mg of Lamotrigine, and Valdoxan. Since cutting down the Seroquel to 100 mg immediate release and adding in 40 mg of Latuda, I'm honestly a new person. No anxiety. Irritability of Seroquel has gone. Anger problems diminished. Honestly, the happiest and most stable I've ever been in my life. Costs a lot (Australia), but worth every cent. 80 mg of Latuda made me too edgy. Been on it for a year and wouldn't change a thing."

• Tor...
• Taken for 1 to 2 years
• August 22, 2019

For Bipolar Disorder "Absolute life changer. Was on 600 mg of Seroquel, 200 mg of Lamotrigine, and Valdoxan. Since cutting down the Seroquel to 100 mg immediate release and adding in 40 mg of Latuda, I'm honestly a new person. No anxiety. Irritability of Seroquel has gone. Anger problems diminished. Honestly, the happiest and most stable I've ever been in my life. Costs a lot (Australia), but worth every cent. 80 mg of Latuda made me too edgy. Been on it for a year and wouldn't change a thing."

• Rat...
• Taken for less than 1 month
• April 21, 2017

For Bipolar Disorder "Horrible drug! My doctor tried it as augmentation therapy for my depression, to take with my Trintellix. The starting baby dose of 20 mg flew me over the edge in two weeks. I became angry, agitated, and very aggressive. A neighbor made me so angry coming out of our condo parking garage the wrong way that I later slashed tires on his car. Not at all like me! Thank God he accepted payment for new tires and didn't press charges. Perhaps the nastiest med I have ever taken. And VERY expensive without good insurance."

• tda...
• Taken for 1 to 6 months
• July 13, 2017

For Bipolar Disorder "My experience with Latuda is mostly negative. I have been on it for 5 months and will be tapering off in a couple of weeks, thankfully. The only good thing about it is it stabilized me in a severe mixed mania with a psychosis episode, but other than that, the side effects are horrible. It has done nothing for my depression the past two months, and I have had anxiety and major irritability on it. The nausea and vomiting are miserable. I was prescribed Zofran to offset the nausea, but that is not so helpful either since the Zofran causes constipation. The 350 calorie requirement is a pain because you can't take it with dinner or you fall asleep instantly, so I take it with a late-night meal to last a few more hours, hence more weight gain."

• Fer...
• Taken for 1 to 6 months
• June 26, 2021

For Bipolar Disorder "I started taking this medication 2 months ago, and it's been a lifesaver. I have bipolar depression terribly, and since taking this medication, I haven't been crying every day or at all for that matter. I don't have random mood swings where I want to go jump off a bridge. The only downside is it's made me more irritable, so my doctor put me on Lamictal 50mg to help with that. Overall, if your insurance will pay for it or you're eligible for the manufacturer coupon, I'd try it. I've been on many other things for my bipolar depression, in and out of hospitals, and this is the only thing that has worked for me."

• Yet...
• Taken for less than 1 month
• April 27, 2017

For Bipolar Disorder "I was put on Latuda recently after switching from Zyprexa because Zyprexa made me extremely fatigued. Latuda doesn't make me as tired except for when I'm driving, when I feel like I'm about to fall asleep at the wheel and sometimes do close my eyes. In addition, I'm hungrier than normal, and even though I'm only eating 1,000 calories or less a day and am exercising at least 4 times a week, I am not losing weight. I feel like I am suffering pointlessly for this. It hasn't helped my depression either. I am irritable a lot of the time and am still having mood swings. I think it may be time for me to quit meds for good. They haven't worked for anyone else in my family, so why should they work for me? I need to get off of them."

• ran...
• Taken for less than 1 month
• September 28, 2017

For Schizophrenia "This is the worst drug I ever took prescribed for schizotypal personality disorder and major depression by one of my past psychiatrists. I don't even understand how this helps other people at all. The psychiatrist thought it might help me, according to her, it was because I mentioned 'anger,' which was very black and white of her. Um, hello...I have severe depression, yet she goes ahead and prescribes me an antipsychotic that shouldn't have been prescribed to someone with depression like me. So, I go on a very low dose, after three days of walking like a zombie, barely able to keep my eyes open, agitated, worse depression, I developed convulsions when trying to sleep on the third night, screaming, crying in pain, barely able to breathe and was rushed to the hospital, given Ativan to calm me down, stopped Latuda entirely."

• Liv...
• Taken for 1 to 2 years
• January 8, 2023

For Bipolar Disorder "I’ve been taking Latuda for 10 months @ 20 mg. I also take mirtazapine at 15 mg. I can’t eat. When I do eat, I feel grossed out by the food. I can’t get myself to take another bite, I have to literally put down the food. And this will be after a while, 16 hours of not eating. This has been going on for about 6 months now. I really like this medicine, and I do feel it is a great fit for me. I don’t mind dealing with this side effect. However, I do notice I am more prone to irritability. I hope I can continue taking these meds while getting my appetite back. I'm not sure if this is common, but if it is, please let me know!"

• th3...
• December 29, 2017

For Bipolar Disorder "I was put on this after Lamictal alone wasn’t cutting it for my mixed depression and hypomania episodes. I’m bipolar type 2. I got up to 60 mg and couldn’t handle the side effects: blurry vision, restless legs, dry mouth, irritability. So I’m now back at 40 mg, and that seems like the perfect dose for me; all side effects have subsided, and I feel more stable."

• CJa...
• Taken for 1 to 6 months
• February 6, 2021

For Bipolar Disorder "I have been taking Latuda 20 mg now for a few months. Prior to Latuda, I was on no medication. I was a great sleeper, going to bed early and waking up late. Now, I am unable to stay asleep. I toss and turn what seems like all night. I used to never recall my dreams, yet now I'm having vivid nightmares of burning bodies and people being chased by unseen entities. I had a vivid dream where I could literally feel myself trying to scream, however, I couldn't get it out. I felt my mouth moving as if I was awake, but I was in fact asleep. It is time for a change. I wake up irritable, angry, and have even begun to have suicidal thoughts, typically soon after waking up in the morning. I cannot stay on this medication. This is so bad for me."

• dop...
• Taken for 1 to 6 months
• June 30, 2018

For Bipolar Disorder "Have been taking Latuda for about a month with two increases, now at 60 mg for the past 4 days. While it has been effective at pulling me out of my most recent depressive episode, and seems to have decreased my chronic anxiety, I am now irritable and having trouble falling asleep at night. Also experienced 2 days of twitching eyelid. But last night, I experienced the worst RLS episode of my life, don’t know if it qualifies as akinesia, but it was severe and disturbing. Plan to decrease back down to 40 mg."

• Bri...
• Taken for less than 1 month
• August 19, 2021

For Bipolar Disorder "I struggle with bipolar depression too, where I don't leave my bed for days. When I started Latuda, I felt amazing. I was awake, laughing... It was like a miracle. That was extremely short-lived. Within 48 hrs, I started to become irrational, angry, irritable, unpredictable. I then wasn't able to sleep for days. In less than 10 days, this medication put me into a full manic attack. I was a completely different person, and not in a good way. I'm now slowly recovering from the manic episode it sent me into."

• Dra...
• Taken for less than 1 month
• June 2, 2017

"I've been on this Latuda 20 mg for about a month for 'depression.' The doctor didn't diagnose me with bipolar or schizophrenia, but she wants me on a mood stabilizer since no antidepressant has ever worked for me. I feel moodier and more irritable. WTF."

• Sam...
• June 9, 2014

For Bipolar Disorder "I've had a horrible experience on this medicine. It makes me really irritable, even more depressed and anxious."

• Anonymous
• August 18, 2011

For Bipolar Disorder "Irritable, agitated, impatient, anxious, and increased anger."

• Anonymous
• August 18, 2011

For Bipolar Disorder "Irritable, agitated, impatient, anxious, and increased anger."