Lumateperone User Reviews & Ratings (Page 3)

• Jason
• Taken for 6 months to 1 year
• October 11, 2023

Caplyta (lumateperone) for Bipolar Disorder "I was prescribed Caplyta 42mg for Bipolar 1 in a mixed state 10 months ago. The first two weeks involved the side effects of other reviews: POUNDING headaches, nausea, severe confusion, and dry mouth. Within the first three days my depression seemed all but canceled out; it took about a week for the mania to subside. I would say that it definitely does the job effectively. I would like to mention though that no other AP has had such a profoundly weird effect on my psyche. From day 1, it seemed to create an uncanny brain fog so thick that it became very difficult to engage externally, but it enabled CRYSTAL clear internal thinking. This was great for therapy, but also intense rumination! My focus and working memory fell under that 'external' part and became so poor that I'm now tapering away in favor of Latuda. Definitely check in with yourself if you try this one out! Despite the inner turmoil, it made me present normally with limited influence on my affect, so only I could see the issue."

• MomInTN
• Taken for less than 1 month
• May 16, 2021

Caplyta (lumateperone) for Schizophrenia "My 21 yr old son's been on this med for Bipolar 1 with psychosis. He has been on it for 3 weeks now after coming off Vraylar, which was great until it stopped working as well (but did cause weight gain). So far the Caplyta is not doing as well, and he's sleeping or about to fall asleep all day. He looks and acts drugged, with slurred speech at times, like he did when he was on Seroquel. And he's having sleep paralysis more often with increased hallucinations at night. Should say he's also on Depakote, Buspar and Lamictal (generic forms) and Ingrezza for muscle spasms, so I'm not sure if there is some interaction or overdosing going on. We talk to his N.P. this week, and he wants off it, when he's awake enough to think about it."

• Jde
• Taken for less than 1 month
• August 12, 2022

Caplyta (lumateperone) for Bipolar Disorder "This was the worst medicine I’ve ever been on. I took it and one hour later my skin was burning and I was so restless despite taking melatonin. Then I fell asleep and woke up with a massive headache, severe dizziness, and nausea. This lasted all day. I couldn’t make food because of dizziness and not that that mattered because I was so nauseous I had no appetite. As the day progressed it never eased to the point where I had to go to the ER. DO NOT TAKE THIS! Try it for yourself but I’m warning you it’s done it’s damage. I’m now terrified to start new meds."

• Working
• Taken for less than 1 month
• July 30, 2022

Caplyta (lumateperone) for Bipolar Disorder "I started July 13, 2022. First dose I woke up feeling like I was a little drunk, enough that I shouldn't have driven. That has gone away. I have frequent urination but this is also waning. My appetite has decreased and I’ve lost almost 9 pounds, which I’ve needed to lose; I hope I lose more! It’s helped me have really deep sleep, I fall asleep fast. It’s helped my depression immensely, I no longer have suicidal ideation and I want to do more things! I’m laughing again and my wit has returned. I’ve noticed a return in my acid reflux, I don’t know if this is because of the medication. My hair isn’t falling out. I think this a great medication and I’m very glad my doc prescribed it to me. I’m excited to see how I’m doing a month in! I take the standard 42 mg. dosage in the evening."

• Mary...
• Taken for 1 to 6 months
• May 28, 2022

Caplyta (lumateperone) for Bipolar Disorder "I was on lamictal and gabapentin successfully for years then last year started having increased anxiety and panic attacks with routine activities so had to change meds. After a less than satisfactory experience with Vraylar—it kept me from suicide so I continued it but the tardive dyskinesia was very uncomfortable and left me with a persistent repetitive movement problem—I started Caplyta as soon as it was approved for bipolar. My mood is stable now and the anxiety and panic I was having have almost completely gone away. I also don’t have to take lunesta for sleep anymore because the insomnia I had for 10 years is gone. One problem I've had is that I wet myself in my sleep if I become intoxicated. My provider said he thought that the CNS depression is so profound that it caused that when alcohol was added to the mix. Thank goodness I didn’t stop breathing. Needless to say I don’t get intoxicated anymore and it doesn’t happen."

• Oklah...
• Taken for 1 to 6 months
• May 16, 2022

Caplyta (lumateperone) for Bipolar Disorder "I find Caplyta to be ineffective. I’ve become very drowsy and have massively increased appetite. For the prescribed purpose, I see no effects. Feels like I’m taking a placebo. This drug is also massively expensive."

• Diane
• Taken for less than 1 month
• May 13, 2023

Caplyta (lumateperone) for Bipolar Disorder "I started Caplyta on April 16 2023 at 10.5 mg. On April 21 I started 21 mg. On April 24 I started 31.5 mg. On April 29th I started 42 mg. I am so severely depressed. Having headaches, coughing, sneezing, a raw nervous stomach, and diarrhea. Don’t know how I am going to continue feeling this way. Suicide ideations are very scary. Is there still hope for me? I can’t decide if I should continue on this medication or not. Not sure how much more misery I can take. I have also considered going back down to 31.5 mg maybe 42 mg is too much for my system. I just need some relief from this depression. I wake up every day not wanting to do another day. I am Bipolar 2 depression. I usually feel good for about 15-19 days of feeling normal and then I tank for 28-25 days. I have been deeply depressed since April 14. I am barely surviving right now. Does anyone have any helpful advice for me?"

• Liv
• Taken for 1 to 6 months
• September 6, 2021

Caplyta (lumateperone) for Schizophrenia "The main psychotic symptom I experience is paranoia. I have cycled through 9 different antipsychotics until I was finally prescribed Caplyta. Past drugs caused extreme weight gain without overeating (40 lbs), major sedation, restlessness, tongue swelling (allergic reaction), akathisia, tardive dyskinesia, impulsiveness, compulsiveness, and terrifying depersonalization & derealization. On Caplyta I experienced extreme sedation and difficulty being productive in the beginning. After 2 months, the sedation went away then I could get tasks done and wake up early. After 5 months I lost 13 lbs without trying. My paranoia is minimized and manageable. This drug is one simple pill that must be taken once a day with the only minor inconvenience of having to be taken with food."

• Anonymous
• Taken for 1 to 2 years
• June 20, 2023

Caplyta (lumateperone) for Bipolar Disorder "For me it was a miracle drug. Absolutely zero side effects. They told me that it would make me sleepy but I didn’t experience that. It has kept my thoughts clear and I don’t feel drugged up all the time."

• Anonymous
• Taken for 1 to 6 months
• November 17, 2022

Caplyta (lumateperone) for Bipolar Disorder "I started Caplyta because I was sick of the weight gain, flat affect, and sedation that I was getting from other antipsychotics. The first two weeks were physically rough. I was waking up after 5 hours of sleep every night, I was incontinent of stool 3x, and I was incredibly nauseous with no appetite to the point where I'd go 5 days without eating. Then, after 2-2.5 weeks, something changed. All the side effects went away and I was finally able to focus on how it made me feel mentally. It has changed my life. My family says I have a completely different personality - one that is engaged in life, confident, calm, social beyond belief, and genuinely happy. I have had no psychosis, and I feel like Caplyta pulled me out of a depression that I had just unconsciously accepted as my "normal". I'm very happy I found this drug and will continue to use it. FYI, I know it's expensive, but if you don't have insurance GoodRx does a great job providing coverage for this medication."

• raaatz
• Taken for 1 to 6 months
• February 4, 2023

Caplyta (lumateperone) for Bipolar Disorder "This medicine changed my life. I’m diagnosed with bipolar and have been in a depressed mood for 2 years. I have been taking caplyta for a month and I haven’t felt this good since I was a child. I luckily have not experienced any of the bad reactions others have mentioned in reviews. The first night I took it I just felt very vulnerable and reality seemed a little shifted, but it wasn’t bad. Positive effects kicked in within a week and I just keep feeling better and better. I slept more than 12 hours before this medication and had absolutely no energy throughout the day. I now have sustained energy and get a healthy 8 hours of sleep. I have developed a good routine and have stuck to it. After 3 weeks, I realized I was able to feel true joy and I laugh more. I enjoy being around others. I have more depth and more clarity. I am able to take it easy and not stress/focus on the bad. I hope this medication continues to work."

• Hrhmi...
• Taken for less than 1 month
• September 21, 2022

Caplyta (lumateperone) for Bipolar Disorder "This is a VERY specialized medication. It’s changing everything for me personally. I work in healthcare & have been on the med merry-go-round for a minimum of 15 years. Diagnosis of MDD, PTSD, Anxiety/panic attacks, & bipolar II. While, obviously, if you are having any life threatening side effects, I highly suggest sticking it out for at least a week. Yes, I had the extremely dry mouth, felt drunk in the AM, dizzy, severely tired for the first 5 days. Then things picked up significantly, to the point where I was afraid I may be experiencing hypo mania. Immediately spoke with my psychiatrist (knows me well, 6+ years) & after explaining my feelings/actions she said that it doesn’t sound like hypomania at all & that, most likely, I am actually feeling happiness for the first time. I have just hit the 2 week mark & am still all over the place as far as sleepy or not, hungry/mildly nauseous, overall; I’m not depressed. TBD but feeling better"

• tery
• Taken for less than 1 month
• May 26, 2023

Caplyta (lumateperone) for Bipolar Disorder "This is a BIG no for me. I took ONE capsule and literally could barely walk I was so tired. Then I woke up with the biggest headache. I couldn't even fathom having to go through a few days of this let alone possibly weeks."

• Your...
• Taken for 1 to 6 months
• August 27, 2022

Caplyta (lumateperone) for Bipolar Disorder "I have a very severe case of bipolar II, I have been on almost every single mood stabilizer, antidepressant, and antipsychotic known to man.. This one did not help me at all. The first week I was very sick (migraine, nausea, stomach pain, heat regulation) but nothing I couldn't push through. After about day 10 something changed in my brain that sent me into a 20 day long manic episode with minor psychosis. Nearly hospitalized when I came off the medication due to withdrawal effects. Not the worst medication I've taken but it's definitely in the top 3"

• Anony...
• Taken for less than 1 month
• February 21, 2023

Caplyta (lumateperone) "I have only just started this medication but I can already notice a huge difference. I no longer experience the negative thoughts that I have experienced for years now. I have tried so many different medications for the severe depression that I experience and this is by far the the most effective medication to date. I have read a lot about the various side effects that people experience when starting this medication and by no means is it my intention to invalidate them as they do exist but they are very manageable and subside very quickly. The biggest thing I have noticed is the residual drowsiness when waking up in the morning however, this subsides pretty quickly after waking up and getting moving. I highly recommend that anyone experiencing severe depression or similar to at least give this medication a try. It might not work for everyone but if you don't try it then you will never know if it works for you."

• Caplyta
• Taken for 6 months to 1 year
• July 29, 2023

Caplyta (lumateperone) for Bipolar Disorder "I love it! When I was first diagnosed with type II bipolar, they put me on 50mg of Lamictal. This was a devil drug for me. It absolutely did the opposite of what it should have and induced more manic episodes than ever. I was flying off the handle at the slightest inconvenience. When I told my psychiatrist, she upped my dosage to 100mg and I began taking 21mg of Caplyta with it. Not much changed with the increase of Lamictal, so I weaned off of it and started taking 42mg of Caplyta alone. (Also, since I've been off of Lamictal, I've had horrific hand and leg tremors - which is known to be associated with quitting it - that drug is HELL!) But since switching over to Caplyta, I feel absolutely great. I'm finally able to feel like myself again. I'm finally happy for the first time in a really long time. I don't have any side effects either - no weight gain, headaches, moodiness, nothing! It's like a complete 180 and I'm beyond thankful for this medication."

• Phil
• Taken for less than 1 month
• March 15, 2022

Caplyta (lumateperone) for Schizophrenia "My son who has bipolar with some schizophrenic symptoms (schizoaffective) did not do well on this medicine. He was hearing people calling him insulting names 24/7! I took him back to his psychiatrist yesterday. He put him back on his original medication, Risperidone, and so far, the voices have already stopped. Thank God! Caplyta. Did not work for him AT ALL!"

• Saraa...
• Taken for less than 1 month
• January 7, 2023

Caplyta (lumateperone) for Bipolar Disorder "(Prescribed for bipolar II) This was the worst experience I’ve ever had with any prescription ever and I only took one pill. In common with other antipsychotics I’ve taken in the past, it made me so lethargic I practically felt drunk. But what was so concerning I actually called the doctors after hours was that I felt unbelievably chilled to the bone (and I’m usually always hot). I was in bed freezing despite wearing 4 blankets, warm fuzzy socks, slippers, pants, 2 sweatshirts, and a beanie. Before the “drunk” feeling kicked in, I had to drive my son to work up the street and I was blasting my heat in the car at 86 degrees! My skin began to burn badly. I can’t explain better than it being like on the verge of frostbite but was warm to the touch on the outside. My feet were and still are the worse. It’s been 8 hours since I took the meds and I’m not too cold anymore but my feet have felt like they’re on fire so bad I’d love to go stick them bare in the snow."

• Dbond...
• Taken for 1 to 2 years
• April 12, 2024

Caplyta (lumateperone) for Bipolar Disorder "I've been taking Caplyta for almost 1 1/2 years. The first day I had a headache, but I read reviews first so I was prepared for it. It went away, the darkness and the negative thoughts started to disappear within a week! I feel Abilify contributed to the darkness, honestly. I will also say I had issues with my bladder as well (more than a few accidents), but I will say to those of you with similar side effects, the bladder control got better after a while so that's not an issue anymore. I take it at night and I do feel like I sleep better at night (especially in comparison to when I forget to take it). No allergic reactions like burning and freezing, so I'm very fortunate. I initially lost about 6 pounds on it, but I have continued to gain again. I'm only taking Caplyta."

• Dream...
• Taken for 1 to 6 months
• July 31, 2021

Caplyta (lumateperone) for Schizophrenia "I am trying this medication for the second time. I was experiencing being off balance and dropping things a lot! I had a couple embarrassing falls. One in my huge driveway! People actually stopped their cars to check on me. My husband seems to think this med helps me more than hinders me. So I'm back on this med. It needs to help me because I'm at my wits end!!!!"

• Littl...
• Taken for less than 1 month
• December 25, 2020

Caplyta (lumateperone) for Schizophrenia "I have been in Capylta for a week for Schizoaffective Disorder. I have had mild nausea, and so far I have gained 2 pounds in the week I have been on it. Will not tolerate weight gain and so far my psychosis is still happening. May go back on Geodon if my symptoms do not improve"

• Anonymous
• Taken for less than 1 month
• January 16, 2023

Caplyta (lumateperone) for Bipolar Disorder "I had a terrible experience with this drug. I only took it once, but within 15 minutes, I began to have a freezing sensation on one arm, then the other. My nose became stuffed up and I couldn't breathe. I couldn't fall asleep. After an hour, I fell asleep, but the next day I was the sickest I had ever been. I couldn't get out of bed and couldn't eat. The freezing sensation was in different places all over the upper half of my body. By 5 pm I was mostly better but the freezing feeling has never gone away. It's been a year. Sometimes it's in my head so bad I can't drive or work. This has been a terrible experience."

• Anonymous
• Taken for less than 1 month
• August 2, 2022

Caplyta (lumateperone) for Bipolar Disorder "I've been on it for 5 days and it is awful!! My mood isn't better. I can't do anything. I feel like crap! My head hurts, my neck is all tensed up constantly, my stomach feels like it's in knots, I don't want to drink anything I have to force myself to drink, I pee every 5 min & I feel like I have a UTI, I just want to sleep, but I can't sleep soundly. It's the worst feeling! I want to just stop taking it, but I'm afraid of what will happen."

• Lala
• Taken for less than 1 month
• September 18, 2022

Caplyta (lumateperone) for Bipolar Disorder "Took 1 pill (low dose to start) in the evening. I don't remember if I took it with food. 1 hour later, my hands and feet started feeling a burning sensation as if I was putting them under an hot heat lamp. No degree of cold (cold water, ice water, ice) helped with the intensity of the feeling of burning. My hands and feet were red but at a regular temperature to the touch. I was eventually able to go to sleep and the burning sensation stopped by the next morning. With that side effect, I did not take another dose. After reading many other people's reviews, I found only .one person who had a similar reaction. It must be very rare. Most reviews I read were very positive. Wish mine had been too. I also contacted the company that makes Caplyta to inform them of the side effect."

• Allan...
• Taken for less than 1 month
• May 28, 2021

Caplyta (lumateperone) for Schizophrenia "I had double vision, and it was very uneasy and hard to walk or stand up I felt like there was 300lbs on my shoulders my neck muscles were very stiff and hurt my legs felt like rubber and my eyes were blinking constantly really fast."