Lumateperone and Diarrhea: What Users Say

• Dia...
• Taken for less than 1 month
• May 13, 2023

For Bipolar Disorder "I started Caplyta on April 16, 2023, at 10.5 mg. On April 21, I started 21 mg. On April 24, I started 31.5 mg. On April 29, I started 42 mg. I am so severely depressed. Having headaches, coughing, sneezing, a raw nervous stomach, and diarrhea. Don’t know how I am going to continue feeling this way. Suicide ideations are very scary. Is there still hope for me? I can’t decide if I should continue on this medication or not. Not sure how much more misery I can take. I have also considered going back down to 31.5 mg, maybe 42 mg is too much for my system. I just need some relief from this depression. I wake up every day not wanting to do another day. I am Bipolar II depression. I usually feel good for about 15-19 days of feeling normal and then I tank for 28-25 days. I have been deeply depressed since April 14. I am barely surviving right now. Does anyone have any helpful advice for me?"

• smo...
• Taken for less than 1 month
• March 13, 2021

For Schizophrenia "Gave it two weeks, I was hoping the side effects would go away, but they only got worse. Nausea, diarrhea, vomiting, restlessness, fatigue. It made my schizoaffective disorder somehow worse, I know this because my symptoms are usually stable. I started pacing around the house, and my 'paranoid senses' were heightened. Therapy seems to help a lot more along with medicine. Therapists give you the tools and skills to deal with most episodes you will have."

• Giu...
• Taken for 1 to 2 years
• June 10, 2023

For Bipolar Disorder "Caplyta is an amazing medication for me! I have largely treatment-resistant Bipolar II depression for 25 years. Caplyta is the BEST antipsychotic used for bipolar disorder that I have ever been prescribed. Only one side effect (stomach upset and diarrhea) the first 3-4 days. I noticed a difference in myself after about 10 days of taking Caplyta. Negative obsessive thoughts, bleak outlook, listlessness, and motivation/energy were the symptoms helped the most. I am living a fuller life filled with hope and motivation. Again, amazing med!"

• Not...
• Taken for less than 1 month
• December 1, 2022

For Bipolar Disorder "I first took Caplyta last night. Within 30 minutes, my skin was on fire! No hives, but like someone else said, Icy Hot. Then I projectile vomited all over my bathroom: nausea, diarrhea, terrible headache, and body aches. I was chilled to my bones and then had hot flashes. Fever of 102.1 that didn’t go away with ibuprofen. Then at 5 am, I started seeing aliens from the corner of my eyes. I took Benadryl and slept with my light on. I had to call into work, and the kids missed school because there was no way I could drive. My body does NOT like this stuff. One and done forever!"

• Van...
• Taken for 1 to 6 months
• December 22, 2022

For Schizophrenia "I am taking Caplyta for schizoaffective disorder and bipolar. I took the 42 mg daily dose for a month. This drug is designed for no tapering. Reading other reviews, I was prepared for 1 to 3 days of headache initially and a niacin-like flushing that made me feel feverish. I was not prepared for my IBD symptoms to worsen. Food I ate would go through me not fully digested. I had diarrhea constantly. Now that I take Latuda, I am regular and have no diarrhea. As far as ameliorating paranoia, I still felt fearful occasionally."

• Suz...
• Taken for less than 1 month
• July 29, 2024

For Bipolar Disorder "Very, very tired. Slurred speech, diarrhea, dry mouth, headaches."