Lisdexamfetamine for Depression User Reviews (Page 2)

• Bar...
• Taken for 1 to 6 months
• March 7, 2025

"As a person with treatment-resistant depression, all antidepressant classes I’ve tried have either had a negative or nonexistent effect on my mental health. I found myself slipping deeper and deeper with every prescription I tried. When I realized the symptoms that caused my depression (low motivation, anhedonia, and poor executive functioning in spite of my intellect) are all things that stimulant medication has been proven to be extremely effective at helping with, I tried to fake an ADHD diagnosis, as I knew trying to ask for them would be seen as drug-seeking behavior. I never got diagnosed with it, but eventually, after my 5th antidepressant didn’t work, my psychiatrist gave it a shot. Let me tell you, this drug saved me, let me connect with friends and family, allowed me to function and complete work and school. This drug is life-changing regardless of the well-deserved stigma around its abuse."

• jm2...
• Taken for 5 to 10 years
• April 30, 2024

"Lisdexamfetamine is the only thing I know that helps my depression. It has to do with it being a prodrug that doesn't release the amphetamine until the body metabolizes it and how that affects the dopamine and norepinephrine. During this 'shortage' of stimulant medications, there are times I haven't been able to get it in time. When it runs out, I am essentially immobilized by my depression. I also get very irritable, so my family suffers. I have taken all the other medications, currently Effexor - never, ever get on this, it is literally impossible for me to get off due to the withdrawal symptoms and am stuck with the minimum dose and side effects for the rest of my life - lamotrigine, and trazodone. Again, lisdexamfetamine is the only thing I know for sure helps me."

• Jon...
• Taken for less than 1 month
• April 6, 2024

"I’ve suffered with treatment-resistant depression since I was 30. I'm now 67... Years of trying at least 10 antidepressants, mixed with Abilify and lamotrigine. I was really struggling with getting out of bed, bathing, feeling like a loser because I thought I was lazy. Worried about losing my marriage because I had little to give. I spent most days in my bedroom sleeping. My new doctor of 3 years has been patient with trying different therapies and combinations. He prescribed lisdexamfetamine along with Prozac and lamotrigine. It has helped so much. It doesn’t make me feel crazy, but it gets me out of bed to complete a few tasks a day, even run errands and make scheduled appointments. I'm feeling like I’m actually participating in life. I sleep fine at night. But there is a BIG problem... my insurance is denying coverage for this drug or generic Adderall. It’s expensive on a fixed income. Adderall is cheaper, but I crash at about 2 pm on it. Lisdexamfetamine is smooth."

• Anonymous
• Taken for less than 1 month
• November 19, 2012

Lisdexamfetamine "I am on my third day of taking this now. First day: mild headache that got worse as the day went on, mild upset stomach, sleeping normal, itchy at night. Second day: bouts of nausea, strange uncomfortable feeling, hot and cold flashes, not a good sleep, itchy at night (worse). Third day: feel really moody, negative, and I have a strange feeling, also exhausted. It clearly isn't for me. I don't feel like 'myself' in three days? Kind of scary."

• Dep...
• Taken for 6 months to 1 year
• March 17, 2017

"Taking Vyvanse for treatment-resistant depression, started to notice half-life extending from 11 hours to 15 hours. Very unusual. The only other med I've taken that has this half-life is Modavigil, does anyone have similar experiences?"

• Mr ...
• Taken for less than 1 month
• June 19, 2019

"I'm a 39-year-old male who suffers from major depressive disorder and chronic fatigue. Things have gotten so bad that I'm on disability and sleep 12-16 hours a day. My doctor prescribed me this in hopes of it boosting my energy. I took my first 30 mg dose this morning. For 3 or 4 hours, my heart was beating out of my chest, and then I crashed. Not a pleasant experience on day 1, I probably won't take this tomorrow."

• All...
• Taken for 5 to 10 years
• May 25, 2017

"Good drug for my condition - drug-resistant depression. Dry mouth is about the only side effect. Hassle to get in KY."

• Ed2...
• December 8, 2015

"I feel great after taking Vyvanse! It's like a miracle! I feel absolutely normal!"

• bre...
• Taken for 6 months to 1 year
• February 14, 2023

"Vyvanse is the only medication that treats my treatment-resistant depression. No side effects."